Objective: To explore the effect of warm acupuncture combined with lumbar core muscle strength training on rehabilitation, quality of life and serum inflammatory factors in patients with lumbar disc herniation (LDH). Methods: 117 patients with LDH who were admitted to our hospital from March 2017 to March 2019 were selected, they were divided into control group (n=58) and study group (n=59) according to the method of random number table. Patients in the control group were given routine rehabilitation training, while those in the study group were given warm needle moxibustion combined with waist core muscle strength training on the basis of the control group. The curative effect, rehabilitation effect and quality of life of the two groups were compared and the changes of serum inflammatory factors. Results: After 4 weeks of treatment, the total clinical effective rate of the study group was higher than that of the control group (P<0.05). The serum levels of interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor -琢 (TNF-琢) in the two groups decreased after 4 weeks of treatment, and the level in the study group was lower than that in the control group (P<0.05). 4 weeks after treatment, Visual pain simulation score (VAS), fairbankjc score of the two groups decreased, and the study group was lower than that of the control group (P<0.05). Japanese Orthopaedic Association assessment of treatment scores (JOA) increased, and the study group was higher than that of the control group(P<0.05). 4 weeks after treatment, the scores of physical role(RP), emotional role(RE), physical function (PF), social function (SF), overall health (GH), physical pain (BP), vitality (VT) and mental health (MH) in the two groups were all increased, and the scores in the study group were higher than those in the control group (P<0.05). Conclusion: Warm acupuncture combined with waist core muscle strength training can improve the rehabilitation effect and quality of life of LDH patients, but also reduce the level of inflammatory factors, the effect is significant. [ABSTRACT FROM AUTHOR]