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This paper reviewed current research status of pain catastrophizing in patients with lung cancer after surgery, and summarized the concept, theoretical basis, assessment tools, epidemiological characteristics, influencing factors and management strategies of pain catastrophizing, in order to provide theoretical support for medical personnel to develop targeted and effective pain management strategies. (综述肺癌术后患者疼痛灾难化的研究现状, 归纳疼痛灾难化的概念、理论基础、评估工具、流行病学特征、影响因素及管理策略, 旨在为医务人员制定针对性、有效性的疼痛管理策略提供理论支持。)

Objective: To investigate the effects of different doses of dexmedetomidine anesthesia for postoperative cognitive function of lung cancer radical resection patients. Methods: 60 cases of patients with lung cancer radical surgery were selected in our hospital, according to the different doses of dexmedetomidine were divided into A group(High Dose of dexmedetomidine group), group B(High Dose of dexmedetomidine group) and group C(without dexmedetomidine). SOD, MDA, recovery time, extubation time and cognitive function were compared before and 1d, 3 d, 5 d after operation. Results: There was no significant difference between the baseline data and operation situation of three groups of patients, P > 0.05. The level of SOD was initially decreased, and then increased after the operation, while the level of MDA was opposite. SOD value in group A on 3rd day was higher than other group, MDA was was significantly lower in group A on day 1 and 3 than the other two groups, P<0.05. The cognitive function after operation was higher in group A than the other two groups, and the recovery time and extubation time in group A was superior to the other two groups, P<0.05. Conclusions: Dexmedetomidine anesthesia can reduce oxidative stress injury, cognitive function in patients withlung cancer after radical operation, shorten the recovery time, drawing tube time. [ABSTRACT FROM AUTHOR]