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旨在为Lipozyme TL IM在鱼油脂质改性及相关功能性产品的研发和应用提供参考，以金枪鱼油为原料，采用固定化脂肪酶Lipozyme TL IM对其进行水解，并分离改性水解甘油酯。采用单因素试验研究了pH、水油比（质量比）、水解温度和水解时间对金枪鱼油水解度的影响，确定了适宜的水解工艺参数，并分析了不同水解度下（20%~50%）改性水解甘油酯的脂肪酸组成、结构、热稳定性和氧化稳定性。结果表明：Lipozyme TL IM水解金枪鱼油的适宜工艺参数为pH 6.0、水油比 3∶ 1、水解温度40 ℃、酶添加量5%（以鱼油质量计），在此条件下水解30、60、80、120 min可分别得到水解度为20%、30%、40%和50%的改性水解甘油酯；随着水解度的增加，所得改性水解甘油酯的多不饱和脂肪酸含量增多，饱和脂肪酸含量减少，结构改变，热稳定性和氧化稳定性变差。综上，可采用Lipozyme TL IM对金枪鱼油进行水解以富集多不饱和脂肪酸，为后续产品开发提供特异性底物。In order to provide a reference for the research and application of Lipozyme TL IM in the modification of fish oil and related functional products, tuna oil was used as raw material, and the immobilized lipase Lipozyme TL IM was used for hydrolysis, and the modified hydrolyzed glycerides were separated. The effects of pH, water-oil ratio (mass ratio), hydrolysis temperature and hydrolysis time on the degree of hydrolysis were studied by single factor experiments, and the appropriate hydrolysis process parameters were determined. In addition, the fatty acid composition, structure, thermal stability and oxidation stability of the modified hydrolyzed glycerides under different degrees of hydrolysis (20%-50%) were analyzed. The results showed that the suitable process parameters for hydrolysis of tuna oil by Lipozyme TL IM was pH 6.0, water-oil ratio 3∶ 1, hydrolysis temperature 40 ℃ and lipase dosage 5% (based on mass of tuna oil). Under these conditions, after hydrolysis for 30, 60, 80 min and 120 min, the modified hydrolyzed glycerides with hydrolysis degrees of 20%, 30%, 40% and 50% were obtained, respectively. With the increase of the hydrolysis degree, the polyunsaturated fatty acid content of modified hydrolyzed glycerides increased, the saturated fatty acid content decreased, the structure changed, and the thermal stability and oxidation stability deteriorated. In conclusion, Lipozyme TL IM can be used to hydrolyze tuna oil to enrich polyunsaturated fatty acids, and provide specific substrates for subsequent product development.

Copyright of Sichuan Mental Health is the property of Sichuan Mental Health Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Research of Soil & Water Conservation is the property of Institute of Soil & Water Conservation, Chinese Academy of Sciences & Ministry of Water Resources and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Southwest China Journal of Agricultural Sciences is the property of Editorial Department of Southwest China Journal of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To explore the correlation between the blood flow parameters of four-dimensional power Doppler ultrasound and the disease stage in patients with cervical cancer. Methods: 80 patients with cervical cancer who were treated in our hospital from August 2019 to July 2022 were selected as the study group, another 50 patients with cervical intraepithelial neoplasia who were admitted to the hospital during the same period were selected as the CIN group, and 50 patients with benign lesions of the uterus at the same period were selected as the control group. Four-dimensional power Doppler ultrasound was performed on them respectively to compare the differences of ultrasound parameters between the three groups, The patients in the study group were divided into different disease stages (stage I 23, stage II 34, stage III 23) according to the FIGO standard, and the differences of ultrasound parameters in different stages of cervical cancer were compared, and the differential value of ultrasound parameters in different stages of cervical cancer was evaluated by drawing the subject curve (ROC). Results: There were significant differences in ultrasound blood flow parameters PSV and RI between the study group, CIN group and the control group, and the difference between the two groups was statistically significant (P<0.05); There were significant differences in ultrasound blood flow parameters among patients with different stages of cervical cancer. PSV of FIGO III was the highest and RI was the lowest. The same difference was statistically significant between the two groups (P<0.05); The AUC of PSV was 0.6829 (95% CI=0.5333-0.8324, P=0.0200) for FIGO I to FIGO II, 0.7698 (95% CI=0.6402-0.8995, P=0.0006) for FIGO II to FIGO III, and 0.7505 (95% CI=0.6072-0.8937, P=0.0036) for FIGO I to FIGO III; The AUC of RI was 0.9309 (95% CI=0.8662-0.9957, P<0.001) for FIGO I to FIGO II, 0.7148 (95% CI=0.5804-0.8493, P=0.0063) for FIGO II to FIGO III, and 0.9811 (95% CI=0.9504-1.000, P<0.001) for FIGO I to FIGO III. Conclusion: The blood flow parameters of four-dimensional power Doppler ultrasound in patients with cervical cancer have a certain correlation with their disease stages. The application of PSV and RI index in the differentiation of cervical cancer stages has good application value and has the significance of popularization and application. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Jilin University (Medicine Edition) is the property of Jilin University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Research of Soil & Water Conservation is the property of Institute of Soil & Water Conservation, Chinese Academy of Sciences & Ministry of Water Resources and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Ordnance Industry Automation is the property of Editorial Board for Ordnance Industry Automation and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Advances in Earth Science (1001-8166) is the property of Advances in Earth Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Engineering for Thermal Energy & Power / Reneng Dongli Gongcheng is the property of Journal of Engineering for Thermal Energy & Power and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

研究益生菌对消化系统牛奶蛋白过敏表现婴儿的体重影响效果。方法 选取2019年1 月至2020年7月该院儿保门诊诊治的85例4~6月龄患儿作为研究对象,受试患儿均有消化系统牛奶蛋白过 敏表现,经开放式牛奶激发试验确诊后,采用深度水解蛋白配方奶喂养。按是否服用了益生菌,将患儿分为益 生菌组45例和对照组40例,比较2组患儿的临床特点、生长发育及体重增长情况。另选取正常足月无牛奶蛋 白过敏表现的人工喂养婴儿41例纳入正常组。结果 连续口服益生菌1、2个月后,益生菌组与对照组患儿呕 吐减少、拒奶减少、腹泻减少、肠鸣大于15次/分的例数比较,差异均无统计学意义(P >0.05);连续口服益生菌 3个月后,2组患儿比较差异有统计学意义(P <0.05)。连续口服益生菌1、2个月后,益生菌组与对照组患儿的 年龄别体重比较,差异均无统计学意义(P >0.05);连续口服益生菌3个月后,2组患儿比较差异有统计学意义 (P <0.05)。连续口服益生菌1、2个月后,益生菌组与正常组婴儿的年龄别体重比较,差异均有统计学意义 (P <0.05);连续口服益生菌3个月后,2组婴儿比较差异无统计学意义(P >0.05)。连续口服益生菌1、2、3个 月后,对照组与正常组婴儿的年龄别体重比较,差异均有统计学意义(P <0.05)。连续口服益生菌1、2、3个月 后,3组婴儿的年龄别身高比较,差异均无统计学意义(P <0.05)。结论 牛奶蛋白过敏表现在消化系统反应 方面,会降低婴儿体重增长速率。但在深度水解蛋白配方奶喂养基础上,辅以益生菌口服连续治疗3个月,则 可以改善婴儿的营养状况,促进体重增长。 [ABSTRACT FROM AUTHOR]

Objective: To explore the diagnostic values of fetal heart ultrasound combined with chromosome detection for fetal cardiovascular malformations. Methods: From June 2017 to December 2020, 117 cases of high-risk pregnant women who were diagnosed and treated in this hospital were selected as the research subjects. All pregnant women were given fetal heart ultrasound and amniocentesis chromosome examination, and were to determine the fetal cardiovascular abnormalities. Results: There were 37 cases of fetal cardiovascular malformations were detected by fetal heart ultrasound in the 117 cases of high-risk pregnant women, accounted for 31.6%.The top three were mainly ventricular septal defect, left superior vena cava, and right subclavian artery. Amniocentesis detected 32 cases of fetuses with chromosomal abnormalities, accounted for 27.4% that 30 cases of abnormal chromosome number and 2 cases of abnormal chromosome structure. The top three were 21-trisomy, 13-trisomy, and 18-trisomy. In the 37 cases of fetal cardiovascular malformations under fetal heart ultrasound examination, there were 30 cases of chromosomal abnormalities. In the 80 cases of fetal cardiovascular abnormalities under fetal heart ultrasound examination, there were 2 cases had chromosomal abnormalities that compared the difference were statistically significant（P<0.05）. There were 39 cases of fetal cardiovascular malformations were jointly diagnosed and 40 cases were diagnosed as fetal cardiovascular malformations after followed-up. The sensitivity and specificity of fetal heart ultrasound combined with chromosome detection for fetal cardiovascular malformations were 100.0%（39/39） and 98.7%（77/78）. Conclusion: Fetal heart ultrasound combined with chromosome detection has high sensitivity and specificity in the diagnosis of fetal cardiovascular malformations.It can increase the detection rate of birth defects as much as possible, and has very good application value. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food & Machinery is the property of Food & Machinery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Reasonable evaluation of the potentiality of three-dimensional land use can promote the fine management of land use, thus it is of great significance to scientific land management and sustainable urban development. Based on four factors, i.e., social and economic status, land use status, comprehensive development opportunity and eco-environmental restriction, an evaluation system with 13 elements was established and indices were calculated with improved polygon area method to evaluate the potentiality of three-dimensional land use. Multiple-source data, such as statistical yearbook data, census data, land use survey data and building survey data, were used to support the analysis. The method was conducted in Shenzhen to validate the effectiveness of the evaluation. For a more accurate evaluation, Delphi method was used in each of the 11 city clusters to determine the relative importance of different factors on the three-dimensional land use in each region, since the dominant functions of different regions were different. The result showed that: the improved polygon area method could reflect the incomplete substitution relation and emphasize synergistic effect between different factors very well. It could be more pertinent to evaluate the potentiality in a region by using a weight matrix adjusted by the regional difference instead of using a uniform weight. From the perspective of single dimension, regions with the best social and economic status gathered in the central urban area of Shenzhen; regions with high score of land use status were disperse; Qianhai- Houhai area and Longgang Center area were regions with greater comprehensive development opportunity; the eco-environmental restriction of urban built-up area near the basic ecological control line could be more strict and less suitable for three-dimensional land use. Overall, the potentiality of three-dimensional land use in Shenzhen decreased from south to north and from west to east. High potentiality areas accounted for 26.46% of build- up areas (extremely high potentiality areas accounted for 8.65%) and showed overall pattern of dispersion with local clusters. Low potentiality areas accounted for 32.21% of build-up areas and mainly located at the periphery part of urban build-up areas. The central urban area and Qianhai-Houhai area were detected as the highest potential areas. In addition, Longhua- Bantian- Buji area, Longgang Center area, Sha Tau Kok and Baoan Airport New Town were regions with higher potentiality of threedimensional land use. In a word, the improved polygon area method can estimate the potentiality of three- dimensional land use in Shenzhen very well. Moreover, it can make the practice of three-dimensional land use more scientific and systematic. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Henan Agricultural Sciences is the property of Editorial Board of Journal of Henan Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective • To identify broad-spectrum bacteriophages against extensively drug-resistant Klebsiella pneumonia and analyze their characteristics by biological and genomic methods. Methods. Multi-drug resistant Klebsiella pneumonia strains collected from a hospital were used as host bacteria to isolate and purify broad-spectrum phages in the wastewater at the same hospital area. The size and shape of phages were observed by transmission electron microscope. Titer, host range, pH stability and thermal stability were measured. Moreover, the DNA extracted from the phage SH-Kp 152234 was sequenced and analyzed. Results • One strain of bacteriophage against Klebsiella pneumonia was isolated and named as SH-Kp 152234. The electron microscope revealed it belongs to Podoviridae family. Moreover, genome of SH-Kp 152234 showed to be a linear double-stranded DNA of 40 578 bp with the GC content of 52.85%. It was predicted to have 49 open reading frames with related known functions. Conclusion • SH-Kp152234, with a broad host range and a short latent period, which could exert its activity in a wide range of temperature and pH, is a promising candidate to be exploited in the treatment of multiple drug-resistant Klebsiella pneumonia. [ABSTRACT FROM AUTHOR]

Copyright of Nanning Zhiye Jishu Xueyuan Xuebao is the property of Nanning College for Vocational Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

中职护理教育是我国医学教育的重要组成部分，担负着为我国医疗卫生事业输送护理人才的重要职责。随着我国人口老龄化程度的快速发展及国家“二胎”政策的全面开放，社会对护理专业人才的需求越来越多，要求越来越高。为了适应时代发展的需要，给社会输送合格的中职护理专业人才，必须结合当前的发展形式重新定位中职护理人才培养目标、课程设置、加强教学内容的整合，通过调整专业教学计划、加强教学研究、改进教学方法等，不断加强内涵建设，提高人才培养质量。 [ABSTRACT FROM AUTHOR]