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This paper introduced the origin, development, operation procedure and mechanism of mindfulness-based stress reduction therapy, and reviewed studies on its application effect in patients with depressive disorders. The related influencing factors of practice, existing problems and future prospects of mindfulness-based stress reduction therapy were analyzed, and suggestions were provided for the future research and clinical application of mindfulness-based stress reduction therapy. (本文综述正念减压疗法的起源及发展、操作过程、作用机制, 以及在抑郁障碍患者中的应用及效果, 分析相关影响因素, 提出现存问题及未来展望, 旨在为今后正念减压疗法应用于更多心理障碍人群提供参考。)

With changes in lifestyle, the incidence of cervical spondylosis is developing at an increasing rate year by year, with the highest incidence being neurogenic cervical spondylosis, which has a great impact on patients' physical, psychological and quality of life. Traditional Chinese Medicine (TCM) nursing techniques have unique advantages over basic nursing operations, such as fewer side effects and higher comfort, and are therefore widely used in the treatment of neurogenic cervical spondylosis, which is the focus of current research and a hot spot. This article reviews the basic concept of neurogenic cervical spondylosis and the clinical practice and research progress of TCM nursing for it. It outlines the current clinical TCM nursing practices applicable to neurogenic cervical spondylosis, their application methods, scope of application and limitations, and aims to provide reference for the formulation and implementation of effective TCM nursing care for patients with neurogenic cervical spondylosis. (神经根型颈椎病严重影响患者的身体、心理和生活质量。中医护理操作具有操作简便、不良反应少、舒适度高等优势, 广泛应用于治疗神经根型颈椎病。本研究就神经根型颈椎病的基础概念及中医护理干预及研究进展进行综述, 概括目前临床适用于神经根型颈椎病的中医护理操作及其应用方法、适用范围及局限性, 旨在为神经根型颈椎病患者制定并实施有效的中医护理提供参考。)

摘要： 探讨血管介入模拟器在临床医学实习生脑血管病教学中的应用效果。 方法 选取2020年7月—2021年12月在解放军总医院第八医学中心神经内科实习的61名临床医学本科生为研究对象，其中33名试验组学员采用血管介入模拟器+传统教学模式进行培训，28名对照组学员采用传统教学模式进行培训。实习结束时通过出科理论知识、实践操作考核成绩以及问卷调查评价两种脑血管病带教模式的效果。 结果 试验组学员出科时理论知识[（88.61±4.05）分 vs.（83.43±4.21）分，P＜0.001]、实践操作[（89.73±3.32）分 vs.（85.54±3.17）分，P＜0.001]考核成绩均高于对照组。问卷调查结果显示：试验组学员对神经内科产生兴趣的程度、对脑血管病认识的程度、自学能力、文献阅读水平均优于对照组，差异有统计学意义（均P＜0.05）。 结论 血管介入模拟器应用于脑血管病临床实习带教中提高了实习生对神经内科的兴趣，培养了实习生的学习主动性，提高了脑血管病临床实习的教学效果。 Abstract: Objective To explore the efficacy of vascular interventional simulator in the clinical teaching of cerebrovascular disease for interns. Methods This study included 61 clinical interns in neurology from the Eighth Medical Center of Chinese PLA General Hospital between July 2020 and December 2021, selecting 33 interns as study group and 28 as control group. The study group received training with vascular interventional simulator combined with traditional teaching method, and the control group received traditional teaching method. The efficacy of two teaching methods were evaluated by questionnaire survey, theoretical knowledge examination, clinical operation examination. Results The scores of theoretical knowledge [ (88.61±4.05) vs. (83.43±4.21), P

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Osteoporosis is an emerging threat characterized by systemic damage to bone mass and microarchitecture leading to fragility fractures. Exosomes are nanosized vesicular particles secreted by cells into the extracellular compartment with biological activities similar to those of their cell of origin and play an important role in intercellular communication processes. Exosomes from multiple cell sources are involved in the regulation of bone-related cell proliferation and differentiation during bone metabolism, and have the advantages of high stability, non-immunogenicity and strong targeting ability, which make up for the shortcomings of traditional drug and stem cell therapies. Exosomes secreted from bone marrow mesenchymal stem cells (MSCs) can promote bone regeneration and improve morphology, biomechanics and histological damage, and exosomes derived from bone marrow mesenchymal stem cells (BMSCs) in the mechanical microenvironment are more effective in inducing osteogenesis, significantly enhancing the osteogenic effect of BMSCs and promoting bone regeneration. Therefore, this article provides a review on the mechano-sensitivity of MSCs, mechanical responsive functionalized exosomes of MSCs, and explores their potential role in the treatment of osteoporosis. [ABSTRACT FROM AUTHOR]

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With the aging of the population, the incidence of osteoporotic fractures has risen, and the financial expenditure on health care has increased. More and more studies have concluded that rehabilitation is an indispensable part of osteoporosis treatment, but for a long time clinicians have had an insufficient degree of awareness of the rehabilitation treatment of osteoporotic fracture, and therapists have lacked standardized criteria in the process of clinical treatment. Therefore, this paper focuses on the rehabilitation treatment of osteoporotic fracture as the central theme, combing the current research status, this paper describes that the standardization of the degree of preoperative rehabilitation should be improved, the analysis of changes in visual analogue scale (VAS) scores should be strengthened in the assessment, the reasonable use of rehabilitation equipment, the application of shock wave and hydrotherapy in osteoporotic fracture should be strengthened, the application of osteoporotic fracture should be strengthened, and the treatment of osteoporotic fracture should be improved., adopt the comprehensive analysis of osteoporotic fracture and other points of view to provide reference and help for subsequent research. [ABSTRACT FROM AUTHOR]

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Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to explore the effects of acid treatment (acid concentration, time and temperature), enzyme preparations (cellulase, xylanase, β-glucanase) on Pleurotus eryngii fungus residue. The experiment used the mushroom residue of Pleurotus eryngii collected in Hebei Province as the raw material, total reducing sugar content as the research index, the factors affecting the acid treatment of P.eryngii residue were analyzed by principal component analysis. At the same time, the effects of enzyme preparation on the reduction of neutral detergent cellulose and acid detergent cellulose were analyzed by orthogonal test. At 40 °C, 2% and 3% acid concentrations would degrade the content of reducing sugar with time. At 60 °C, the increase of acid concentration could slow down the degradation of total reducing sugar. At 80°C, 1% and 2% acid concentrations could promote the degradation of polysaccharides and increase the content of total reducing sugar. According to the principal component analysis, temperature was the most important factor affecting the content of reducing sugar of P.eryngii slag. The orthogonal test results showed that the degradation of xylanase and cellulase were the main factors affecting the reduced amount of neutral detergent cellulose and acid detergent cellulose respectively. The optimal enzymolysis formula was cellulase 85 U/mL, xylanase 220 U/mL and glucanase 40 U/mL.. These results indicated that the bacterial residue after acid and enzyme treatment has nutritional value as a ruminant feed. [ABSTRACT FROM AUTHOR]

ATM: To explore the impact of Yunvjian on palmitic acid （PA）-induced injury of intestinal L cells. METHODS: （ 1） Various concentrations（ 1. 5, 3 and 6 g/L） of Yunvjian solution and 1, 1-diphenyl-2-picrylhydrazyl （DPPH·） solution （100 mg/L） were incubated in darkness for 30 min. A full-wavelength microplate reader was employed to measure the absorbance, thereby assessing the scavenging effect of Yunvjian on DPPH·. （2） Mouse intestinal endocrine cell line GLUTag was divided into control group, PA group, PA+Yunvjian（ 1. 5 g/L） group, PA+Yunvjian（ 3 g/L） group, and PA+Yunvjian （6 g/L） group. The influence of Yunvjian on PA-induced apoptosis was ascertained through Hoechst 33342 nuclear staining and MTT assay. （3） The GLUTag cells were divided into control group, PA group, and PA+Yunvjian （6 g/L） group. The expression of glucagon-like peptide-1 （GLP-1） was quantified by immunofluorescence staining. The level of reactive oxygen species （ROS） was determined using 2', 7'-dichlorofluorescein diacetate （DCFHDA） fluorescent probe, and superoxide dismutase 1 （SOD1） protein level was analyzed by Western blot. RESULTS: （1） Yunvjian exhibited significant DPPH· scavenging activity in vitro（ P<0. 01）.（ 2） Compared with PA group, Yunvjian markedly attenuated PA-induced decrease in GLUTag cell viability in a concentration-dependent manner, with the most pronounced effect observed at 6 g/L （P<0. 01）. （3） Compared with PA group, 6 g/L Yunvjian significantly enhanced the expression of GLP-1 （P<0. 05） and SOD1 （P<0. 01）, but reduced ROS level （P<0. 01） in GLUTag cells. CONCLUSION: Yunvjian potentially mitigates PA-induced injury in GLUTag cells by diminishing intracellular oxidative stress. [ABSTRACT FROM AUTHOR]

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