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Copyright of Fudan University Journal of Medical Sciences is the property of Fudan University Journal of Medical Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

研究了冷压初榨椰子油对四氯化碳（CCl4）诱导昆明小鼠急性肝损伤的保护作用。将72只昆明小鼠随机分成6组，包括正常组、四氯化碳肝损伤模型组、联苯双酯组（150 mg/kg）、椰子油低剂量组（5 mL/kg）、椰子油中剂量组（10 mL/kg）、椰子油高剂量组（20 mL/kg），通过测定小鼠血清中丙氨酸转氨酶（ALT）、天冬氨酸转氨酶（AST）、乳酸脱氢酶（LDH）、甘油三酯（TG）和总胆固醇（TC）指标，肝组织中超氧化物歧化酶（SOD）活力、谷胱甘肽过氧化物酶（GSH-Px）活力及丙二醛（MDA）含量，采用HE染色切片对小鼠肝脏组织进行病理学检查，考察冷压初榨椰子油对四氯化碳致小鼠急性肝损伤的保护作用。结果表明：与模型组相比，不同剂量组的冷压初榨椰子油（5、10 mL/kg和20 mL/kg）可以不同程度地降低小鼠血清中ALT、AST、LDH、TG、TC水平以及肝组织中MDA含量，提高肝组织中SOD活力与GSH-Px活力；同时，肝脏组织病理学观察与生化指标检测结果一致。其中，高剂量的冷压初榨椰子油(20 mL/kg)作用效果优于阳性对照联苯双酯。研究表明冷压初榨椰子油对肝脏具有较好的保护作用，作用机制可能与其含有较多的抗氧化物质以及功能性物质有关。The hepatoprotective effects of virgin cold-pressed coconut oil (VCPCO) against carbon tetrachloride (CCl4) induced acute liver injury in Kunming (KM) mice were studied. A total of 72 Kunming mice were randomly divided into 6 groups, including normal group, CCl4 liver injury model group, bifendate group (150 mg/kg), coconut oil low dosage group (5 mL/kg), coconut oil medium dosage group (10 mL/kg) and coconut oil high dosage group (20 mL/kg). The levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), triglyceride (TG), total cholesterol (TC) in serum, and superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and malondialdehyde (MDA) in liver were determined. The liver tissue was examined pathologically by HE staining section. The results showed that VCPCO with dosages of 5, 10 mL/kg and 20 mL/kg could decrease the levels of ALT, AST, LDH, TG, TC in serum and MDA in liver, and increase the levels of SOD and GSH-Px in liver. Meanwhile, the results of liver histopathology were consistent with those of biochemical markers. Among them, the effect of high dosage of VCPCO (20 mL/kg) was better than the positive control bifendate. Results indicated that VCPCO had a good protective effect on liver, and the mechanism might be related to its high content of antioxidative and functional compounds.

Greenhouse gases refer to gases that can absorb long-wave radiation in the earth's atmosphere and cause atmospheric temperature to rise, among which carbon dioxide, methane, nitrous oxide and fluorine are the gases that have the most prominent impact on climate change. Greenhouse gas emissions from animal husbandry account for a large proportion of the total global emissions. Therefore, in order to reduce the impact of animal husbandry on climate change, it is particularly important to control greenhouse gas emissions from cowshed. At present, there are two main ways to control greenhouse gas emissions from cowshed: Improving the production mode and management mode of animal husbandry to reduce greenhouse gas generation, control greenhouse gas emissions through technical means. This paper explains the toxic effect of greenhouse gases emitted by cattle in cowshed, emphatically analyzes the related factors affecting greenhouse gas emissions and its control methods, discusses various greenhouse gas emission reduction control measures from the perspectives of feed composition and additive regulation, adsorbent placement in the cowshed environment, and environmental optimization outside of the cowshed, and analyzes the advantages and existing problems of the existing technologies, to provide references for promoting environmentally friendly, sustainable scientific livestock and poultry farming practices. [ABSTRACT FROM AUTHOR]

Copyright of Tianjin Medical Journal is the property of Tianjin Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Molecular Science is the property of Journal of Molecular Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to solve the problem that the rolling bearing working environment was more complex and the fault characteristic signal was easily affected by noise and difficult to be discriminated, a fault feature extraction method of bearing outer ring based on whale optimization algorithm (WOA) of variational modal decomposition (VMD) combined with multipoint optimal minimum entropy deconvolution adjusted (MOMEDA) was proposed. First of all, the simulated signal was decomposed using VMD, and the optimal number of decomposition layers and the sample entropy of each component was determined using WOA. Then the optimal component containing the fault signal was obtained with the minimum value of sample entropy as the target search. The best component obtained was reconstructed by MOMEDA, and the fault characteristic frequency of the simulated signal and its multiplier frequency were obtained from the envelope spectrum of the reconstructed signal. Finally, In order to verify the effectiveness of WOA-VMD combined with MOMEDA, data were collected on the experimental platform, and the characteristics of outer ring fault signals of rolling bearings were extracted. The experimental results show that the method can be used to efficiently decompose the signal seeking, and can more accurately obtain the fault frequency of 100 Hz of the simulated signal and the approximate fault frequency of 87.5 Hz of the extracted signal of the experimental bench using the method, which verifies the effectiveness of the method. The research results show that WOA-VMD combined with MOMEDA can effectively extract the fault characteristic signal of rolling bearing under the condition of low signal-to-noise ratio and extract the fault characteristic frequency from the reconstructed signal. [ABSTRACT FROM AUTHOR]

Objective: To study the genetic variation characteristics of HPV56 E6, E7 and L1 in patients with precancerous lesions infected with HPV56, and to obtain the molecular epidemiological data of HPV56 in patients with precancerous lesions of cervical cancer in Yunnan. Methods: A total of 300 cervical intraepithelial neoplasia patients were enrolled and HPV genotyping kit was used to detect the types of HPV infection in the patients. The HPV E6, E7, and L1 genes in patients infected with HPV 56 were sequenced. Finally, the lineage distribution of HPV 56 and the genetic variations of HPV 56 E6, E7, and L1 genes in the study subjects were analyzed. Results: In this study, the HPV56 virus infected by the study subjects mainly belonged to the A lineage, with more than 90% belonged to the A lineage, and about 10% belonged to the B lineage. There were 13 mutation loci in the E6, E7 and L1 genes of HPV56, including 6 in the E6 gene, 4 in the E7 gene and 3 in the L1 gene. Among the 6 mutation sites of HPV56 E6 gene, 2 were synonymous mutations (T158C (S19S), G437A (P112P)), and 4 were non-synonymous mutations (A141C (S14R), A241G (N47S), A263C (K54N), G279A (D60N)). The four mutation sites of HPV56 E7 gene were all non-synonymous mutations (C601A (D10E), G605A (V12I), G770C (E67Q), G802C (Q77H)). Among the three mutation sites of HPV56 L1 gene, two were synonymous mutations (G6454T (P321P), A6868C (I459I)), and one was non-synonymous mutation (A5867G (N126D)). Conclusion: This study obtained preliminary data on the genetic variations of HPV 56 E6, E7, and L1 genes in CIN patients in Yunnan area, and obtained the molecular epidemiological characteristics of HPV 56 E6, E7, and L1 genes. It provides necessary data for further analysis of the molecular epidemiological characteristics of HPV 56 E6, E7, and L1 genes in CIN patients in Yunnan area. [ABSTRACT FROM AUTHOR]

Copyright of Inorganic Chemicals Industry is the property of Editorial Office of Inorganic Chemicals Industry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Dalian Ocean University is the property of Journal of Dalian Ocean University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background and purpose: The interaction of CXC motif chemokine receptor (CXCR) on the cell surface of multiple myeloma (MM) with chemokines in the bone marrow microenvironment is involved in proliferation, survival and extramedullary invasion of MM cells. Sinomenine derivative YL064 exerts its biological effects by targeting intracellular signaling regulators in MM cells. This study aimed to explore possible modulating and biological effects of sinomenine derivative YL064 on CXCR3 in MM cells. Methods: The MM cell lines H929 and MM1.S were used as in vitro models. H929-OE and MM1.S-OE cells with stable overexpression of CXCR3 were constructed with lentivirus vector. The effects of CXCR3 on clonal formation and migration of MM cells were detected by clone spot formation and transwell migration assay. Meanwhile, flow cytometry was used to analyze apoptotic rates of H929, H929-OE, MM1.S and MM1.S-OE cells treated with different concentrations of YL064. Furthermore, real-time fluorescence quantitative polymerase chain reaction (RTFQ-PCR) and Western blot assay were applied to detect expression levels of CXCR3 and its downstream signal regulators extracellular regulated protein kinase (ERK) and p-protein kinase B (p-AKT) in H929 and MM1.S cells before and after the treatment with YL064. Results: The clonal formation rates of H929-OE and MM1.S-OE cells with CXCR3 overexpression reached to 81.33%±5.79% and 73.00%±4.90%, which were significantly higher compared with H929 (58.33%±3.30%) and MM1.S cells (41.00%±3.14%). The migration proportion of H929-OE and MM1.S-OE cells were 7.90%±0.81% and 23.00%±1.63%, which were significantly higher compared with H929 (4.63%±0.37%) and MM1.S cells (14.63%±1.04%). After treatment with YL064, the apoptotic rates of H929-OE and MM1.S-OE cells were 29.80%±0.30% and 14.20%±0.26%, which were lower than those of H929 (33.40%±0.25%) and MM1.S cells (21.60%±0.21%). It was also shown that YL064 could reduce clonal formation and migration, inhibit CXCR3 gene transcription and downregulate expressions of CXCR3, ERK and AKT in H929 and MM1.S cells. Conclusions: CXCR3 might promote proliferation and invasion of MM cells. Sinomenine derivative YL064 could downregulate expressions of CXCR3 and its downstream signal regulators in MM cells, reduce abilities of clonal formation and migration, and induce apoptosis. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Capital Institute of Physical Education is the property of Shoudu Tiyu Xueyuan and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electric Drive is the property of Electric Drive Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Polycystic ovary syndrome (PCOS) is one of the most common reproductive disorders in women worldwide, and its symptoms are mainly manifested as ovulation, endocrine and metabolic abnormalities. Although the pathogenesis of PCOS is not yet clear, more and more studies have demonstrated that high-concentration androgen-induced neuroendocrine disorders play a role in the pathogenesis of PCOS. The KNDy neurons in the hypothalamus play an important role in regulating female reproductive function. Recent studies have found that excessive concentrations of androgens may alter the regulation of GnRH by the KNDy neuronal network in the hypothalamus region, interfering with the hypothalamic -pituitary -ovarian/adrenal/ adipocyte axis, which may increase the production of downstream target organs. The vicious cycle of excess androgens, aggravates the symptoms of PCOS. Therefore, it may be possible to treat PCOS patients by reducing androgen effects on neuroendocrine, restoring sensitivity to steroid feedback, and normalizing LH/FSH pulses by modulating GnRH secretion during critical developmental windows. [ABSTRACT FROM AUTHOR]

Copyright of Acta Prataculturae Sinica is the property of Acta Prataculturae Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agricultural Big Data is the property of Journal of Agricultural Big Data Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agricultural Big Data is the property of Journal of Agricultural Big Data Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Experimental Technology & Management is the property of Experimental Technology & Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Engineering Geology / Gongcheng Dizhi Xuebao is the property of Journal of Engineering Geology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Applied Ecology / Yingyong Shengtai Xuebao is the property of Chinese Journal of Applied Ecology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Storage & Process is the property of Tianjin Academy of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of China University of Petroleum is the property of China University of Petroleum and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Experimental Technology & Management is the property of Experimental Technology & Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Education Exploration is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Oil Drilling & Production Technology / Shiyou Zuancai Gongyi is the property of Shiyou Zuancai Gongyi Bianjibu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

对比观察不同阈值下腔静脉塌陷指数（IVC-CI）导向补液预防骨科手术患者腰麻后低血压的效果， 并从血流动力学、容量反应、容量状态及血管活性物质等方面分析其原因。方法选取拟行骨科腰麻手术患者201 例，按随机数字表法分为三组各67例；对照组常规补液，不进行超声检查和液体预补充；IVC-1组、IVC-2组均行下腔 静脉超声监测，分别以IVC-CI>50%、>40%为阈值导向补液。观察腰麻后低血压发生情况，记录血管活性药物使用 情况；比较三组入手术室（T0）、麻醉即刻（T1）、麻醉后5 min（T2）、麻醉后10 min（T3）时的血流动力学［心率（HR）、平均 动脉压（MAP）］、容量反应［心输出量（CO）］，T3时容量状态［每搏量变异度（SVV）］，腰麻前补液量、总补液量，T0、T3 时血清血管活性物质血栓素B2（TXB2）、血管紧张素Ⅱ（AngⅡ）、内皮素（ET）。结果腰麻后低血压发生率、血管活 性药物使用率IVC-2组IVC-1组、对照组（P 均<0. 05）。三组T2、T3时CO较T0、T1时呈下降趋势（P 均<0. 05），且IVC-2组>IVC-1组>对照 组（P 均<0. 05）。T3时SVV IVC-2组< IVC-1组< 对照组（P 均<0. 05）。腰麻前补液量IVC-2组>IVC-1组，总补液量 IVC-2组>IVC-1组>对照组（P 均<0. 05）。三组T3时血清TXB2、AngⅡ、ET水平均低于T0时（P 均<0. 05），且IVC-2组> IVC-1组>对照组（P 均<0. 05）。结论以IVC-CI>40%或>50%为阈值导向补液均能降低骨科手术患者腰麻后低血 压发生率，但前者更显著；这可能与其更能稳定血流动力学，改善容量反应、容量状态，提高腰麻前补液量、总补液 量，降低缩血管活性物质波动幅度，减少血管活性药物使用有关。 [ABSTRACT FROM AUTHOR]

Because feature selection in an unsupervised environment lacks dependence on category information, this paper proposed a disagreement measure (DAM) with the use of the fuzzy rough set theory. DAM measured the degree of difference in meaning of fuzzy equivalence of any two feature sets or features. On this basis, this paper proposed the DAMUFS unsupervised feature selection algorithm. The DAMUFS algorithm could select feature subsets that contained more information under unsupervised conditions, while also ensuring that the attribute redundancy in the feature subset was as small as possible. The experiment compared the classification performance of DAMUFS algorithm with some unsupervised and supervised feature selection algorithms on multiple data sets. And the results prove the effectiveness of DAMUFS algorithm. [ABSTRACT FROM AUTHOR]

Copyright of Experimental Technology & Management is the property of Experimental Technology & Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Fudan University Journal of Medical Sciences is the property of Fudan University Journal of Medical Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Experimental Technology & Management is the property of Experimental Technology & Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)