Search

目的 比较不同类型脑桥梗死的病因机制和临床特征。 方法 选择脑桥梗死患者75例，分为基底动脉狭窄组9例和基底动脉无狭窄组66例，其中基底动脉 无狭窄组又分为穿支病变组33例和小动脉病变组33例。比较各组的临床特征与影像学变化。 结果 在各组的临床特征中，基底动脉狭窄组的糖尿病、冠状动脉粥样硬化性心脏病、合并其 他颅内血管中重度狭窄、神经功能缺损进展发生率、入院美国国立卫生研究院卒中量表（National Institutes of Health Stroke Scale，NIHSS）评分、出院NIHSS评分、出院改良Rankin量表（modified Rankin Scal e，mRS）评分≥3比例较其他组增高（P＜0.05）。穿支动脉病变组空腹血糖、餐后2 h血糖、糖化血 红蛋白、入院收缩压、梗死灶大小、入院NIHSS、出院NIHSS评分、神经功能缺损进展、出院mRS评分比 例高于小动脉病变组（P＜0.05）。 结论 脑桥梗死存在不同的病因和发病机制。脑桥旁正中动脉梗死及合并基底动脉狭窄的脑桥梗 死病变以动脉粥样硬化为主，病灶大，症状重，易发生进展，预后不良。 Abstract: Objective To compare the clinical features and the pathogenesis of different types of pontine infarction. Methods A total of 75 patients with pontine infarction were divided into basilar artery stenosis group (n =9) and basilar artery non-stenosis group (n =66). Among which , basilar artery nonstenosis group were divided into perforating disease group (n =33) and small artery disease group (n =33). The clinical features and imaging changes of each group were compared. Results The incidence of diabetes mellitus, coronary heart disease, intracranial artery atherosclerotic stenosis, admission National Institutes of Health Stroke Scale (NIHSS) score, discharged NIHSS score and modified Rankin Scale (mRS) score ≥3 were significantly higher in BA stenosis group (P

层绞式海底光缆具有通信容量大的优势,抗压扁性能是海底光缆最重要的性能之一。文章采用有限元分析软件,对两种典型结构的层绞式海底光缆进行抗压扁仿真,对仿真结果进行了对比分析,明确了层绞式海底光缆抗压扁性能的影响因素,得出的结论对层绞式海底光缆的设计有一定的指导意义。

以太网无源光网络（EPON）在光纤到户（FTTH）系统中是一项非常实用的技术,它可以优化网络的结构,提高网络的带宽,充分利用网络的资源。文章首先介绍EPON的网络结构和语音在EPON中实现的一些进展,然后分析EPON系统对传统公共交换电话网（PSTN）和下一代网络（NGN）语音的支持及支持的几种NGN协议,最后简单地分析了实验结果以证明其优势所在。

Objective To analyze the clinical value of oxygen saturation related diffusion index for monitoring oxygen and status in patients with acute respiratory distress syndrome(ARDS). Methods The enrolled cases were 130 patients with ARDS treated in the hospital from May 2017 to January 2020. The oxygen saturation related diffusion indexes were assessed and compared between patients with mild, moderate and severe ARDS. Results Of the 130 patients with ARDS, 38 were mild, accounting for 29. 23%; 55 were moderate, accounting for 42. 31%; and 37 were severe, accounting for 28. 46%. Refers to oxygen saturation-related diffusion index, mild ARDS patients were significantly higher than moderate patients, moderate patients were significantly higher than severe patients(P＜0. 05). Conclusion Finger oxygen saturation-related diffusion index has a negative correlation with the condition of patients with ARDS. Strengthening the monitoring of finger oxygen saturation-related diffusion index is of great significance for assessing the condition, treatment effect and prognosis of ARDS patients. (目的 分析应用指氧饱和度相关弥散指数监测急性呼吸窘迫综合征(ARDS)患者氧合状态的临床价值。方法 选取医院2017年5月—2020年1月收治的130例ARDS患者为研究对象, 对比轻度、中度、重度ARDS患者指氧饱和度相关弥散指数。结果 130例ARDS患者中38(29. 23%)例轻度, 55(42. 31%)例中度, 37(28. 46%)例重度。指氧饱和度相关弥散指数: 轻度ARDS患者明显高于中度患者, 中度患者明显高于重度患者, 差异有统计学意义(P

In order to solve the problems such as insufficient interaction modeling and low prediction accuracy due to the lack of partial pedestrian modeling ideas, the lack of global vision in time dimension, and the neglect of the diversity of pedestrian interaction modes, this paper proposed an improved model STG-DTBTA based on Social-STGCNN. Firstly, the model constructed PPM module, and pruned the pedestrians inter links that were not meet constraints such as distance threshold for denoising. Secondly, the model introduced the spatio-temporal attention mechanism. Spatial attention dynamically assigned interactive weights, and set up multiple attention heads to deal with the interaction diversity problem. Temporal attention captured temporal dependencies of temporal data. Finally, the model used Bi-TCN to increase global perspective to capture dynamic patterns and trends in trajectory data, and used gating mechanism to incorporate the bidirectional features. The experimental results on the datasets ETH and UCY show that compared with Social-STGCNN, ADE and FDE are decreased by an ave rage of 8% and 16% respectively when the number of parameters and the inference time kept close to it. The STG-DTBTA has good interactive modeling ability, model performance and prediction effect. [ABSTRACT FROM AUTHOR]

Copyright of Nonferrous Metals Engineering is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Liquid Crystal & Displays is the property of Chinese Journal of Liquid Crystal & Displays and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Science & Biotechnology is the property of Journal of Food Science & Biotechnology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Machine Tool & Hydraulics is the property of Guangzhou Mechanical Engineering Research Institute (GMERI) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Mechanical Engineering is the property of Editorial Board of China Mechanical Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Anhui Agricultural Sciences is the property of Journal of Anhui Agricultural Sciences Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nonferrous Metals Engineering is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Teacher Education Research is the property of Teacher Education Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

It is known that SMAD specific E3 ubiquitin protein ligase 1 (SMURF1) mediates autophagy through its E3 ubiquitin ligase activity, but the ubiquitinated substrates of SMURF1 need to be further explored. In this paper, the interacting proteins of SMURF1 in THP-1 cells were captured and identified by co-immunoprecipitation (Co-IP) combined with mass spectrometry. It was found that SMURF1 could physically bind to 222 proteins in THP-1 cells, and Adenosine deaminase acting on RNA 1 (ADAR1) had a higher peptide binding score. SMURF1 overexpression vectors were constructed and transfected into HEK-293T cells, then Co-IP and Western blotting assays verified the interaction between exogenous SMURF1 and endogenous ADAR1. qRT-PCR and Western blotting assays were carried out after transfecting SMURF1 overexpression vectors in HEK-293T cells, which identified that overexpression of SMURF1 attenuated the protein levels of ADAR1 (P＜0.05). However, there was no significant difference in the mRNA level of ADAR1. HEK-293T cells with normal and overexpressing SMURF1 were treated with cycloheximide (CHX), respectively, and Western blotting assays showed a shortened half-life of ADAR1 after overexpression of SMURF1 (P<0.05). Furthermore, overexpression of SMURF1 increased the polyubiquitination level of ADAR1 as detected by Co-IP and Western blot (P＜0.05). After the proteasome inhibitor (MG132) treatment, the Western blotting assay was performed to demonstrate that the negative regulatory effect of SMURF1 on ADAR1 was weakened after the proteasome degradation pathway was attenuated (P<0.05). This study shows that SMURF1 interacts with ADAR1, catalyzes the polyubiquitination of ADAR1 and mediates its degradation through the proteasome pathway, which provides a theoretical basis for exploring the various biological functions of SMURF1 by affecting the stability of ADAR1. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Chongqing University of Posts & Telecommunications (Natural Science Edition) is the property of Chongqing University of Posts & Telecommunications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Nursing in Practice is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shanghai Jiaotong University (Medical Science) is the property of Journal of Shanghai Jiaotong University (Medical Science) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Functional Materials / Gongneng Cailiao is the property of Chongqing Functional Materials Periodical Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Tobacco Science & Technology is the property of Tobacco Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Tobacco Science & Technology is the property of Tobacco Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective·To investigate the expression of tetraspanin 1 (TSPAN1) in breast cancer and its effect on the migration and invasion of breast cancer cells. Methods·Immunohistochemistry staining (IHC) was used to detect the expression of TSPAN1 in breast cancer tissues and para-tumor tissues from 106 clinical patients, and to analyze its correlation with the clinical characteristics of patients. The Cancer Genome Atlas (TCGA) database was used to analyze the expression of TSPAN1 mRNA in breast cancer tissues and para-tumor tissues, and its correlation with the clinical characteristics of patients. After down-regulation of TSPAN1 in breast cancer cells MDA-MB-231 and SUM159PT, the effects of TSPAN1 on migration and invasion of cells were detected by wound healing assay and transwell assay, and the expression of epithelial-mesenchymal transition (EMT) -related proteins (E-cadherin, Ncadherin and vimentin) were detected by Western blotting. Results·IHC results showed that the expression of TSPAN1 in breast cancer tissues was higher than that in para-tumor tissues (P=0.000), and the expression of TSPAN1 in total TNM stages, M stages, N stages and pathological grades of breast cancer tissues showed statistically significant differences (all P<0.05). The results of transcriptome sequencing data from TCGA database showed that the expression of TSPAN1 mRNA in breast cancer tissues was higher than that in para-tumor tissues (P=0.000), and its expression in TNM Ⅲ‒Ⅳ stages was higher than that in TNMⅠ‒Ⅱ stages (P=0.007). After down-regulation of TSPAN1, the migration and invasion ability of MDA-MB-231 and SUM159PT cells were decreased, the expression of E-cadherin was increased and the expressions of N-cadherin and vimentin were decreased (all P<0.05). Conclusion·TSPAN1 is highly expressed in breast cancer tissues, which can promote the migration and invasion of breast cancer cells. [ABSTRACT FROM AUTHOR]

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao is the property of Journal of Chinese Institute of Food Science & Technology Periodical Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Lubrication Engineering (0254-0150) is the property of Editorial Office of LUBRICATION ENGINEERING and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To explore the correlation of disease perception status, hope level and quality of life in patients with liver cancer. 126 patients with liver cancer in our hospital from October 2017 to October 2020 were selected. The perception status of patients was assessed by the brief illness perception questionnaire (BIPQ), the hope level was assessed by Herth hope index (HHI), and the quality of life was assessed by the 36-item medical outcomes study short-form (SF-36). The relationship between BIPQ, HHI scores and clinical data of liver cancer patients was analyzed. According to the BIPQ scores of patients with liver cancer, they were divided into BIPQ≥ 48 scores group and BIPQ＜48 scores group. According to HHI scores, they were divided into HHI≥ 24 scores group and HHI＜ 24 scores group. The SF-36 scores of patients with different BIPQ and HHI scores were compared, and the correlation between BIPQ, HHI scores and SF-36 scores in patients with liver cancer. were analyzed. The BIPQ score of patients with educational years <9 years, clinical stage III and combined with liver cirrhosis were higher than those of patients with educational years ≥ 9 years, clinical stage I-II and patients without liver cirrhosis. And the HHI score of patients with educational years <9 years, clinical stage III, family monthly income <3000 yuan and combined with liver cirrhosis were lower than those of patients with educational years ≥ 9 years, clinical stage I-II, family monthly income ≥ 3000 yuan and patients without liver cirrhosis (P<0.05). The social function, physical function, mental health, physical pain, energy, physical role function, emotional role function and overall health scores of the BIPQ≥ 48 scores group were lower than those in the BIPQ<48 scores group, and the scores of the HHI≥ 24 scores group were higher than those in the HHI<24 scores group (P<0.05). The BIPQ score was negatively correlated with the SF-36 dimension scores, and the HHI score was positively correlated with the SF-36 dimension scores (P<0.05). The disease perception status and hope level of liver cancer patients are affected by many factors, and they are closely related to the quality of life. The lower the negative perception of disease and the higher the hope level of patients with liver cancer, the better the quality of life. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Shanghai Jiaotong University (Medical Science) is the property of Journal of Shanghai Jiaotong University (Medical Science) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Tobacco Science & Technology is the property of Tobacco Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hydrobiology / Shuisheng Shengwu Xuebao is the property of Editorial Department of Journal of Hydrobiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Northern Agriculture / Beifang Nongye Xuebao is the property of Journal of Northern Agriculture Editorial and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Henan Agricultural Sciences is the property of Editorial Board of Journal of Henan Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food & Machinery is the property of Food & Machinery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)