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为实现“双碳”目标，缓解环境压力，综合能源系统（integrated energy system，IES）已成为能源转型的重要发展方向之一。考虑到电转气（power-to-gas，P2G）技术引入的氢气、合成天然气等多类型供气源混合的问题，传统的IES能量流计算已无法确定混合后的燃气品质是否达标，无法量化其对IES中的节点压力、电压等参数影响。为此，提出了一种计及气体成分变化的电-气-热综合能源系统能量流计算方法。首先，将气体相对密度和热值建模为迭代变量，给出了混合气体的相对密度和热值的节点偏差方程及求解流程，为IES中多种供气源及其混合问题提供了通用模型；其次，提出了扩展牛顿-拉夫逊求解方法，给出反映耦合关系的扩展雅可比矩阵，以实现更全面的能量流结果评估和运行分析；最后，通过算例验证了所提模型和方法可有效反映气体成分变化对耦合系统的影响。

在含高比例可再生能源的新型电力系统中，由于不考虑电力电子变换器的阻抗特性，使得潮流计算的精度降低。为此，需要一种基于本地控制器阻抗特性的由大量分布式发电机组成的新型电力系统潮流计算方法。首先，基于小信号扰动法和dq轴、αβ轴、abc轴之间的等效变换，对变换器的源端等效输出阻抗矩阵进行了估计。然后将总线-分布式电源等效阻抗模型转化为总线-总线的阻抗模型。同时，将等效阻抗模型嵌入雅可比矩阵迭代过程中，提高了潮流计算方法的精度。最后，利用IEEE-4 总线测试系统、PG&E-69 总线测试系统和IEEE-118 总线测试系统对基于本地控制器阻抗特性的潮流计算进行了仿真，表明所提出的潮流计算方法更为准确。

目的探讨小鼠的杏仁核中C1q/C3补体系统在诱导抑郁样行为过程中的作用途径。方法本实验分3部分：① 采用慢性束缚压力方法建立小鼠抑郁模型，将12只8周龄雄性C57BL/6小鼠随机分为对照（WT）组和抑郁模型（CRS）组，各6只，抑郁模型组造模2周。行为学测试系统悬尾实验（TST）、强迫游泳实验（FST）测试小鼠抑郁状态，采用免疫荧光染色法检测小鼠杏仁核中突触素（Syn）和突触后致密物（PSD95）变化情况，小胶质细胞（Iba-1）和星形胶质细胞（GFAP）细胞荧光强度，C1q、C3含量。② 6只8周CX3CR1-GFP雄性鼠，随机分为GFP组以及GFP模型（GFP+CRS）组，各3只，采用免疫荧光染色法观察小胶质细胞及星形胶质细胞相互作用情况。③ 12只8周龄雄性C57BL/6和12只C1q-/-小鼠随机分为对照（WT）组，抑郁模型（CRS）组，C1q敲除（C1q-/-）组，C1q敲除模型（C1q-/-+CRS）组，各6只，模型组组造模2周，行为学TST、FST检测4组小鼠抑郁状态，采用免疫荧光染色法检测四组小鼠杏仁核部位突触Syn和PSD95变化。结果行为学分析结果显示：与WT组比较CRS组在TST和FST中不动时间明显升高（PPP=0.003 8）；与WT组比较CRS组杏仁核内Iba-1和GFAP明显激活（P=0.000 4， P=0.003）且与WT组比较CRS组杏仁核内小胶质细胞与星形胶质细胞相互作用明显；与WT组比较CRS组杏仁核内C1q与C3产生明显增多（P=0.000 2， P=0.011 9）；行为学分析，WT、CRS、C1q-/-、C1q-/-+CRS 4组综合比较，在TST中，与CRS组比较，WT组不动时间明显升高，C1q-/-+CRS组不动时间也明显增高（均PC1q-/-+CRS组不动时间也明显增高（均P<0.001）； 与CRS组比较WT组与C1q-/-+CRS组杏仁核内突触Syn明显增多（PPPC1q基因缺陷阻断CRS诱导的小鼠突触丢失和抑郁样行为。

慢光在未来全光网络通信中具有重要作用。文章提出一种基于零对比度光栅共振诱导透明效应的可实现平面外慢光滤波的设计,该设计兼具优良的透射滤波功能和慢光效应。分析了刻蚀深度和光栅周期对慢光滤波性能的影响,指出刻蚀深度影响波导层对共振诱导模式的束缚,刻蚀深度的改变将显著降低零对比度光栅的慢光滤波性能;而光栅周期主要影响入射光与波导模的相位匹配,选取不同光栅周期可在C波段实现对不同慢光滤波通道的选择。此外,研究了斜入射条件的模式劈裂效应,指出由于斜入射条件下非简并共振波导模的激发,±1级劈裂模式被激发,其虽然导致峰值透射的降低,但可以显著提高透射慢光的群折射率。该研究为慢光器件的设计提供了一种新的解决方案。

提出了一种窄刻槽亚波长金属波导光栅透射滤波器的设计,其工作原理是利用窄光栅刻槽取得低透射背景,再利用导模共振与表面等离子激元共振的混合产生峰值透射,进而实现良好的窄带透射滤波效应。研究发现,利用多模共振与表面等离子激元共振的混合模式,通过增加波导厚度即可实现性能良好的双通道透射滤波,在波长1 412和1 653nm处,峰值透射率分别为72.1%和63.6%。进一步分析表明,由于长波处磁场能量较多地局域在金属光栅层,峰值位置和峰值透射率受光栅深度变化影响显著;而短波处磁场能量较多地局域在波导层中,因此短波处峰值漂移对波导层厚度变化更为敏感。

To address the problems of landslide hazard sample selection as well as long-term dependencies, gradient vanishing, and degradation in deep learning models, a CF-CNN-LSTM deep learning model is proposed. This model combines the certainty factor (CF) method, convolution neural network (CNN), and long short-term memory (LSTM) networks. Taking the Wuzhou Municipal District of Zhuang Autonomous Region, Guangxi as the study area, 13 kinds of landslide evaluation factors such as elevation, slope, slope direction, etc. were selected. The CF-CNN-LSTM model was used to evaluate the susceptibility of landslide in the study area, and compared with the CNN model, the LSTM model, the recurrent neural network model, the logistic regression model, and the prediction accuracy of the model were evaluated by six methods such as the working characteristic curve of the subjects and the overall accuracy. The results show that the AUC value of the ROC curve of the CF-CNN-LSTM model is 0.953, higher than that of other single models. At the same time, the other five assessment indexes are all better than that of the single model, which proves that the CF-CNN-LSTM model has a higher accuracy, and it can be used for landslide susceptibility evaluation in the Wuzhou City area, and it can provide scientific suggestions for landslide risk management in the region. [ABSTRACT FROM AUTHOR]

Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To investigate the association between urinary lead and nonalcoholic fatty liver disease (NAFLD) . Methods The participants, aged ≥18 years, were selected from the 2017—2020 National Health and Nutrition Examination Survey (NHANES), with the exclusion of the participants with a lack of liver transient elastography data and urinary lead markers and those with hepatitis B, hepatitis C, and significant alcohol consumption. A total of 2 492 participants were enrolled and divided into NAFLD group with 852 participants and non-NAFLD group with 1 640 participants. High-performance liquid chromatographyelectrospray ionization-tandem mass spectrometry and online solid-phase extraction combined with isotope dilution were used to measure urinary lead level. The independent-samples t test or the Wilcoxon rank sum test was used for comparison of continuous data between two groups, and the chi-square test or the Fisher’s exact test was used for comparison of categorical data between two groups. Multivariate Logistic regression analysis, restricted cubic spline, subgroup analysis, and interaction analysis were used to investigate the association between urinary lead and NAFLD. Results The NAFLD group had a significantly higher urinary lead level than the non-NAFLD group (Z= − 2.023，P=0.043) . After adjustment of the covariates of age, sex, race, marital status, education, family income-to-poverty ratio, body mass index, smoking, drinking, diabetes mellitus, hypertension, and hyperlipidemia，there was a significant increase in the risk of NAFLD in the Q3 urinary lead group (odds ratio [OR] =1.360，95% confidence interval [CI] ：1.019—1.817，P=0.037) . There was a positive dose-response relationship between urinary lead and the risk of NAFLD (P=0.047), which was a non-linear relationship (Pnon-linear=0.037) . There was a significant interaction between urinary lead and race, and for every quartile increase in urinary lead, the risk of NAFLD in Mexican-Americans was increased by 32.40% (OR= 1.324，95%CI：1.017—1.632，P<0.05) . Conclusion Urinary lead level is significantly associated with the risk of NAFLD. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Applied Ecology / Yingyong Shengtai Xuebao is the property of Chinese Journal of Applied Ecology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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[Objective] Increasing the spatial resolution of transcriptome gene expression can improve the accuracy of cell lineage and type changes in genetic development and disease studies, providing more detailed molecular phenotypic information. [Method] Using image segmentation to simulate the spatial distribution of cells in a spatial transcriptomics grid, the high-resolution spatial gene expression using linear interpolation was reconstructed. Graph clustering methods were used to reveal the spatial preferences of cell distribution within tissues. [Result] Application of SpaGMM on the 10X Visium dataset of the mouse posterior brain helped to accurately identify various spatial domains of the mouse brain. Compared with several commonly used methods for spatial transcriptome clustering, the results showed that the clustering results by SpaGMM were more consistent with the annotated histological regions, which were supported by the spatial expression of many marker genes. SpaGMM also recognized layers corresponding to Purkinje cells and Bergmann glial cells from mouse cerebellum, revealing complementary gene expression patterns in different cell layers. [Conclusion] SpaGMM may reveal the fine structure of tissue domains by improving the spatial resolution of spots. [ABSTRACT FROM AUTHOR]

With the popularization of phacoemulsification surgery for cataracts and the widespread use of intraocular lenses (IOL), the incidence of IOL dislocation is increasing. The pathogenesis may be related to progressive zonular dysfunction and capsular contraction. IOL dislocation can be classified into different types according to the timing and location of the IOL dislocation. Management of IOL dislocation includes conservative observation, IOL repositioning, IOL refixation, and IOL replacement. The treatment plan for IOL dislocation is determined by the clinical characteristics of the individual case, such as choosing anterior or pars plana vitrectomy, IOL refixation or replacement, and IOL suture or no suture. There are various surgical treatment methods for IOL dislocation without capsular support. Understanding the disease, early prevention, improving surgical skills, rational use of capsular tension rings, strengthening postoperative follow-up, and mastering treatment methods and the indications for various IOL dislocations can minimize the occurrence and harm of IOL dislocation. [ABSTRACT FROM AUTHOR]

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Coordinating the coordinated development of the ecological environment and social economy is an important content for realizing sustainable development in ecologically fragile areas. In this paper, Lianghe, Yunnan was taken as a typical research area of ecologically vulnerable areas in Southwest China. We used the assessment index and method of “barometer of sustainable” to assess sustainable development of Lianghe County by entropy method and weighted summation model. The results showed that: (1) The humanities welfare index of Lianghe County was increasing year by year from 2012 to 2017, but there were fluctuations in 2018. The per capita grain possession, the per capita net income of farmers and the per capita GDP were the main factors affecting the improvement of humanities welfare index in Lianghe County. (2) In addition to the fluctuation in 2017, the ecological welfare index of Lianghe county was increasing year by year from 2012 to 2018, and the ecological welfare entered a stage of sustainable development in 2018. (3) From 2012 to 2018, the sustainable development status of Lianghe County showed as three different states: unsustainable development, medium development and basic sustainable development. It entered the stage of basic sustainable development of Lianghe County in 2016, but it was not yet in the stage of sustainable development. [ABSTRACT FROM AUTHOR]

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Objective　To investigate the association between urinary thallium （TL） and nonalcoholic fatty liver disease （NAFLD). Methods　Related data were collected from the registered participants aged ≥18 years in National Health and Nutrition Examination Survey from 2017 to 2020， with th exclusion of the individuals with a lack of liver transient elastography data and urinary TL indicators and those with hepatitis B， hepatitis C or significant alcohol consumption. A total of individuals were divided into NAFLD group and non-NAFLD group. Urinary TL level was quantitatively measured using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry and online solid-phase extraction combined with isotope dilution. The two groups were compared in terms of age， sex， race， marital status， education， family income poverty impact ratio （FMPIR), body mass index（ BMI), smoking， alcohol consumption， diabetes mellitus（ DM), （HL), and urinary TL level. The independent-samples t test or the Wilcoxon rank-sum test was used for comparison of continuous data between two groups， and the chi-square test was used for comparison of categorical data between two groups. Descriptive analysis， multivariable Logistic regression， restricted cubic spline regression analysis， subgroup analysis， and interaction analysis were conducted to investigate the risk association between urinary TL and NAFLD. Results　A total of 2 511 individuals were included， with 1 612 （64.20%） in the NAFLD group and 899 （35.80%） in the non-NAFLD group， and the NAFLD group had a significantly higher urinary TL level than the non-NAFLD group ［0.18 （0.11 — 0.26）μg/L vs 0.16 （0.09 — 0.25）μg/L， Z=−2.76， P= 0.01］. After adjustment for the covariates of age， sex， race， education， marital status， FMPIR， BMI， smoking， alcohol consumption， DM， HTN， and HL， the urinary TL Q4 group had a significant increase in the risk of NAFLD （odds ratio ［OR］= 1.90， 95% confidence interval［ CI］： 1.48 — 2.44， P<0.01). There was a positive dose-response relationship（ P<0.01） and a non-linear relationship （P<0.01） between urinary TL and the risk of NAFLD. A significant interaction was observed between urinary TL and smoking/BMI （P<0.05). For individuals taking ≥100 cigarettes in their lifetime， the risk of NAFLD was increased by 50% for every quartile increase in urinary TL （OR=1.50， 95%CI： 1.24 — 1.80), and for individuals taking<100 cigarettes in their lifetime， the risk of NAFLD was increased by 20% for every quartile increase in urinary TL （OR=1.20， 95%CI： 1.03 — 1.40）； for individuals with a BMI of ≥30 kg/m2， the risk of NAFLD was increased by 30% for every quartile increase in urinary TL （OR=1.30， 95%CI： 1.05 — 1.70), with a statistical significance（ P<0.05). Conclusion　Urinary TL level is significantly associated with the risk of NAFLD.hypertension（ HTN), hyperlipidemia [ABSTRACT FROM AUTHOR]

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Based on memory protection key hardware extensions, a lightweight and fine-grained page protection mechanism is proposed. This mechanism overcomes the technical limitations of traditional page protection methods that only support page-grained memory access monitoring, and achieves finegrained page protection that can intercept each memory access operation. By fully utilizing the user-level thread-local page access permission control provided by memory protection keys, the performance overhead is reduced by more than 30% compared to traditional page protection. Through the integration of fine-grained page protection and compiler instrumentation, the limitations of traditional compiler instrumentation methods that cannot cover non-recompilable portions of programs are addressed. [ABSTRACT FROM AUTHOR]

The 14th Five-Year Plan states the following: "Accelerate the construction of digital countryside, build a comprehensive information service system for agriculture and rural areas, establish an inclusive service mechanism for agriculture-related information, and promote the digitalization of rural management services." As an important combination of "Digital China" and "rural revitalization" strategies, the so-called digital countryside not only helps promote the development of digital agriculture but also is an important aspect of rural digital governance, which is significant in the modernization of agriculture and rural areas. The spatial collaborative development of a county digital countryside needs to re-examine the spatial and temporal patterns related to the development of a county digital countryside. Accordingly, this study adopts an exploratory spatial data analysis method to study the spatial autocorrelation characteristics related to the development of a county digital countryside. The three-stage nested Theil index method is used to measure the spatial difference characteristics regarding the development of a county digital countryside. The driving factors behind the development of the digital countryside are determined via the geographic detector analysis method. Subsequently, this study presents that the development level of China's county-level digital villages shows obvious "gradient" characteristics, and the development level of digital villages gradually decreases from east to west. Moreover, the digital villages show "flake distribution" in the Yangtze River Delta region, and "dot distribution" in the western and northeast regions. China's county-level digital villages exhibit the spatial characteristics of "large agglomeration and small dispersion." The regions with high development level of digital villages are mainly distributed in the Yangtze River Delta urban agglomeration and spread around Jiangsu and Zhejiang provinces as the center. The spatial autocorrelation index between county digital countryside, rural financial infrastructure, rural digital infrastructure, rural economy digitization, rural governance digitization, and rural life digitization is significantly positive, indicating that the development of digital countryside has significant spatial autocorrelation characteristics and is affected by geographical proximity. For example, a county unit with high digital rural development level is commonly adjacent to another county unit with the same high digital rural development level. The development of China's county-level digital villages exhibits obvious spatial agglomeration characteristics, forming "highhigh" agglomeration in the Yangtze River Delta region with higher economic development level and relatively perfect network infrastructure. Digital rural development presents a "center-periphery" structure with sub-hot spots and hot spots clustered around high hot spots. A T-shaped strip is formed between the hot and cold spot areas to separate them. The overall Gini coefficient of rural digital development at the county level in China is 0.035 9, and the regional gap in rural digital development is the main source of this gap. The industrial economy, population, education, finance, and infrastructure strongly influence the spatial distribution of the digital countryside. The contribution of this study is mainly reflected in revealing the spatial pattern, spatial difference, spatial agglomeration, and driving factors behind the development of the digital countryside from the perspective of a county level, which enriches the relevant research on the spatial analysis of the digital countryside and provides empirical evidence for promoting the collaborative development of the digital countryside. [ABSTRACT FROM AUTHOR]

Copyright of Oil Drilling & Production Technology / Shiyou Zuancai Gongyi is the property of Shiyou Zuancai Gongyi Bianjibu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)