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Post-stroke patients often show different degrees of limb hemiplegia. Symptoms include muscle weakness, especially hand motor dysfunction. This paper summarized the studies about Traditional Chinese Medicine treatment for hand motor dysfunction in post-stroke hemiplegic patients, and provided reference for rehabilitation treatment and exercise of hand motor function in post-stroke hemiplegic patients. (脑卒中患者会遗留有不同程度的肢体功能损伤, 尤其是手功能障碍。本文就脑卒中偏瘫患者手功能障碍的中医治疗方法进行综述, 旨在为脑卒中患者手功能康复治疗及锻炼提供参考依据。)

Objective To investigate the effect of care bundles in fall risk management of inpatients in Department of Neurology. Methods Totally 260 inpatients with high risk of falling were randomly divided into the control group and observation group, with 130 cases in each group. All patients received routine nursing strategy for fall prevention. Based on the literature review and interview analysis, intervention strategy with care bundles was established to enhance the fall prevention. Incidence of in-hospital fall status and patient satisfaction were measured and compared between two groups. Results The incidence of in-hospital fall status in the observation group was lower than that in the control group (13. 85% vs. 27. 69%, P＜0. 05). The score of satisfaction assessment in the observation group was higher than that in the control group(P＜0. 01). Conclusion Care bundles have proven to be effective in the fall prevention among inpatients in the Department of Neurology. It can reduce the Incidence of in-hospital falls and ensure patient safety during hospitalization (目的 探讨集束化护理干预策略在神经内科住院高危跌倒患者风险管理中的应用。方法 选取2023年1月—5月医院住院的高危跌倒患者260例随机分为对照组和观察组, 各130例。对照组实施防跌倒常规措施; 观察组在常规护理措施基础上, 基于文献阅读和访谈结果制定集束化护理方案。评估两组患者跌倒状态发生情况, 调查患者满意度。结果 观察组跌倒状态发生率13. 85%(18/130), 低于对照组的27. 69%(36/130), 差异有统计学意义(P＜0. 05)。观察组满意度评分高于对照组的, 差异有统计学意义(P＜0. 01)。结论 对神经内科住院患者实施集束化护理干预措施, 能有效降低患者跌倒状态发生率, 提高患者医疗安全。)

Objective To establish a comprehensive, scientific, and reasonable smart home automation system for patients with ischemic stroke and functional impairment by conducting a questionnaire survey on the requirements of a smart home automation system. Methods The researchers developed a questionnaire titled "Requirements of a smart home automation system for patients with ischemic stroke and functional impairment" to assess the specific needs of patients who suffered from ischemic stroke and were unable to live independently. A total of 100 patients participated in the survey. Results The results of the questionnaire survey involving 100 individuals revealed that only 43. 00%(43/100)of the respondents were familiar with intelligent home systems, and a mere 21. 00%(21/100)had previous experience with similar smart systems. When asked about their willingness to accept a smart home automation system that could be installed and customized to provide convenience in daily life, including monitoring vital signs and medication usage, as well as aiding in rehabilitation training, 46. 00%(46/100) of the participants expressed their willingness of acceptance. Further investigation revealed that complex operation, impractical function and expensive cost were main reasons behind the reluctance of the rest 54 individuals to accept the system. The respondents expressed the highest demand for the electronic medication box monitoring system, followed by the sleep monitoring system and the vital sign monitoring system. Conclusion The findings indicated that patients with ischemic stroke and functional impairment had limited awareness and acceptance of smart home automation system. In order to ensure that the implementation of this automation system provides tangible benefits to patients, it is crucial to enhance its functionality, actively promote awareness among the target population, and establish an effective foundation for subsequent clinical trials of the intelligent home management system software. (目的 调查脑梗死伴功能障碍患者对智慧居家管理模块的需求, 为进一步建立完善、科学、合理的智慧居家管理模块提供依据。方法 采用自拟“脑梗死伴功能障碍患者对智慧居家模块的需求”调查问卷, 选取2020年4月—2023年4月医院收治的100例脑梗死伴功能障碍中生活不能完全自理的患者进行调查。结果 43(43. 00%)例患者了解智慧居家系统, 但只有21(21. 00%)例患者使用过类似的智能系统。当被问及“有一个智慧居家管理系统, 可在现有居家电器、门、窗等基础上进行安装改造, 旨在为您解决居家不便、进行生命体征及服药监测、帮助您进行康复训练等, 是否愿意接受”时, 46(46. 00%)例患者表示愿意接受, 而不愿意接受的原因包括操作复杂、实用性低、价格昂贵。患者对智慧居家管理系统功能的需求程度排前三位的分别是电子药盒监测系统、睡眠监测系统和生命体征监测系统。结论 脑梗死伴功能障碍患者对于智慧居家模块的了解程度低、接受意愿较低; 应通过加强功能完善、积极宣传普及等措施, 为智慧居家管理系统软件后期投入临床试验提供有效基础, 确保智慧居家模块的实施能够给患者带来确切益处。)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Paint & Coatings Industry (0253-4312) is the property of Paint & Coatings Industry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Rheumatoid arthritis is an inflammatory disease. Many studies have shown that wogonin has a good anti-inflammatory effect on rheumatoid arthritis, but its exact efficacy and specific mechanism of action remain to be clarified. OBJECTIVE: To investigate the mechanism of wogonin ameliorating joint inflammation by regulating endoplasmic reticulum stress pathway in rats with collagen- induced arthritis. METHODS: (1) At the animal level: Female Wistar rats were divided into healthy control group, arthritis model group and wogonin treatment group. Rat models of arthritis in the latter two groups were established by subcutaneous injection of bovine type II collagen and adjuvant. In the wogonin group, wogonin was given by gavage for 28 consecutive days after modeling. During this period, the rats in each group were weighed, and arthritis score and ankle swelling were measured every 7 days. After the experiment, the pathological changes of the joint were observed, the mRNA and protein levels of endoplasmic reticulum stress pathway GRP78 and CHOP were detected by qRT-PCR, western blot, and immunohistochemistry. (2) At the cellular level, cell counting kit-8 was used to detect the cytotoxic effect of wogonin on fibroblast-like synoviocytes from rats with collagen-induced arthritis. The fibroblast-like synoviocytes induced by thapsigargin were treated with different concentrations of wogonin. The levels of interleukin-1β and tumor necrosis factor-α in the cell supernatant were detected by ELISA, and the intracellular reactive oxygen species in each group were determined by DCFH-DA probe method. The mRNA and protein levels of GRP78, IRE1α, XBP1s and CHOP were detected by qRT-PCR and western blot, respectively. RESULTS AND CONCLUSION: Compared with the healthy control group, arthritis index score and ankle swelling degree in the arthritis model group were increased (P < 0.01), synovial hyperplasia, inflammatory cell infiltration, cartilage destruction and bone erosion were observed in pathological sections, and the mRNA and protein expressions of GRP78 and CHOP in the ankle were significantly increased (P < 0.01), which were mainly located in synovial tissue and articular surface. Compared with the arthritis model group, the arthritis index score and ankle swelling degree in the wogonin treatment group were decreased (P < 0.05), synovial hyperplasia and the number of inflammatory cells were decreased, cartilage destruction and bone erosion were alleviated, the mRNA and protein expression levels of GRP78 and CHOP in the ankle were decreased (P < 0.05), particularly in synovial tissue and on the articular surface. There was no significant difference in body mass among the three groups (P > 0.05). In the cell experiment, 200 μmol/L wogonin significantly reduced the survival rate of fibroblast-like synoviocytes (P < 0.01). Compared with the blank control group, the levels of interleukin-1β, tumor necrosis factor-α, content of reactive oxygen species, and mRNA and protein expression of GRP78, IRE1α, XBP1s, and CHOP in the thapsigargin group were significantly increased (P < 0.05); compared with the thapsigargin group, 50 and 100 μmol/L wogonin significantly reduced the levels of interleukin-1β and tumor necrosis factor-α in the cell supernatant (P < 0.05, P < 0.01), and 100 μmol/L wogonin significantly reduced the content of reactive oxygen species (P < 0.01) and down-regulated the mRNA and protein expression levels of GRP78, IRE1α, XBP1s and CHOP (all P < 0.05). These results suggest that wogonin can effectively alleviate joint inflammatory responses in rats with collagen-induced arthritis, and the endoplasmic reticulum stress pathway may be the key target of its intervention. [ABSTRACT FROM AUTHOR]

Nanoscale zinc oxide is a multifunctional nanomaterial extensively utilized across various domains due to its exceptional physicochemical properties. Traditional synthesis methods often face challenges such as high costs, complex procedures, and product instability. The microemulsion synthesis overcomes these issues, offering simplicity, cost-effectiveness, and controllable produce dimensions. Notably, the use of waste soybean oil as an emulsifier in the synthesis process aligns with the principles of green chemistry and sustainable development, highlighting waste material reuse. The nanoscale zinc oxide products were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), and chemical analysis. This approach fosters a comprehensive integration of inorganic synthesis, chemical and instrument analysis, aiming to enhance the holistic experimental capabilities of university students. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Nanjing Medical University: Natural Sciences is the property of Journal of Nanjing Medicial University (NMU) Medical Publications Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Pancreatic cancer is a highly lethal and aggressive tumor that affects the digestive tract，leading to poor prognosis and low survival rate. At present，gemcitabine⁃based chemotherapy is widely used in the clinical treatment of pancreatic cancer. However，the efficacy of chemotherapy has significantly decreased with the emergence of clinical drug resistance. In order to meet its demand of energy and biological materials，tumors always change its metabolic pathway，which is called tumor metabolic reprogramming. The abnormal enhancement of aerobic glycolysis is one of characteristics of glucose metabolic reprogramming in pancreatic cancer cells. The glucose transporter proteins and key enzymes are participated in the processes and regulated chemotherapy resistance through different signal pathways. The purpose of this study is to summarize the relationship between drug resistance and glucose metabolic reprogramming in pancreatic cancer. The mechanisms and regulatory signaling pathways are also analyzed. Furthermore，the pre⁃clinical trials and drug development targeting the glycolysis metabolic pathways are summarized and analyzed. [ABSTRACT FROM AUTHOR]

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Copyright of Nonferrous Metals Engineering is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The development of adjacent homogeneous tourism resource sites not only has the effect of enhancing tourism attraction with regional commonality, but also has obvious regional tourism substitution effect. Therefore, different models are often adopted in tourism development and operation to achieve different tourist experience effects and obtain better revenue. Based on the field survey and data analysis of Xidi and Hongcun villages in Yixian County, which are located in the same Hui cultural region, this paper finds that the development and operation models of the two villages have their own advantages and disadvantages, and different development models have an important impact on the perception of tourists and villagers. Combined with the new trend of tourism development, this paper discusses the strategy of protective development of ancient villages in the new stage, hoping to provide demonstration and reference for similar ancient village tourism development. [ABSTRACT FROM AUTHOR]

Molecular imprinting technology is a technology that simulates the interaction between enzymes, substrates, antigens and antibodies, and specifically identifies imprinted molecules, which can specifically identify templates or analogues, and is often used in the pretreatment of analytical samples for efficient extraction and purification of samples. Macrolides are one of the commonly used antibiotics in animal husbandry, which are widely used in the prevention and treatment of respiratory tract and gastrointestinal infections in livestock and poultiy, but non-standard use may lead to residues in the production of animal products and the environment, posing a threat to human health. The paper reviews the research progress of molecular imprinting technology for the detection of macrolide drag residues, focusing on the introduction of molecularly imprinted solid phase extraction and magnetic molecularly imprinted solid phase extraction, and prospects for the application of molecular imprinting technology in the pretreatment of macrolide drag residue analysis, so as to provide reference for optimi方ng the pretreatment method of macrolide antibiotics detection. [ABSTRACT FROM AUTHOR]

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Copyright of Science & Technology of Food Industry is the property of Science & Technology of Food Industry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The aircraft surface icing changes the flight dynamics characteristics of the aircraft and seriously threatens flight safety. Therefore, aircraft anti-icing technology is of great significance for safe flight. The basic principle, type, and influence of aircraft icing methods were analyzed and the existing anti-icing technology methods were summarized and compared. At the same time, the research status of superhydrophobic materials was comprehensively reviewed, and its specific conditions ( superhydrophobic property failure) were analyzed, especially the existing problems and challenges. Secondly, based on the defects of a single anti-icing system, a composite anti-icing system was proposed, and several composite anti-icing systems were introduced and compared with a single antiicing system. In addition, aiming at the possible problems in the application of superhydrophobic materials, an aircraft anti-icing system combining loop heat pipe and superhydrophobic materials was proposed. Finally, the problems of superhydrophobic coating surfaces and composite anti-icing and deicing systems were analyzed and prospected. It can be seen that the hybrid anti-icing and deicing system has good application potential. [ABSTRACT FROM AUTHOR]

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自然环境是场地的构成要素之一，也是建筑物赖以存在的物质前提.有关自然环境与建筑之间的关系，通常存在2类观点，即认为两者为异质系统以及将两者视为有机整体.将此2种观点引入景观构筑物这类特殊景观建筑的设计中，深入剖析不同视角主导下截然不同的结构构思与表现方法，并以翔实而丰富的案例进行佐证.研究表明，场地自然环境是景观构筑物结构构思的制约因素与结构形态的外在形式动力，而景观构筑物以最终的结构形态反作用于自然环境，表达不同的环境主张.两者之间的互动有效拓展了景观构筑物的设计思想与方法，推动自然环境与建筑的关系朝着良性、可持续的方向发展.

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Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Tungsten disulfide has become a very potential anode material for sodium ion batteries because of its unique layered structure and large interlayer spacing. However, its further wide application is limited by its poor conductivity and easy volume expansion during charging and discharging. In this paper, using tungsten hexachloride, thioacetamide and self-made hollow carbon shell as raw materials, a hollow rod-shaped C/WS2 composite material was synthesized by solvothermal method, and it was used in sodium ion battery to improve the above problems. The results show that the specific capacity of C/WS2, electrode can still reach 417. 1 mAh g-1 after 90 cycles at the current density of 2 A g-1. Under the high current density of 10.0 A g-1, it also has a specific capacity of 343. 3 mAh g-1. Therefore, the hollow rod-shaped C/WS2, composite material has excellent sodium storage performance. [ABSTRACT FROM AUTHOR]

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