1. Risk factors analysis and modeling prediction of non-alcoholic fatty liver disease in asymptomatic young adults (青年无症状体检人群非酒精性脂肪肝危险因素分析及建模预测)
- Author
-
LIU Xiaoliu (刘晓柳), GAO Yunfei (高芸飞), WANG Haibo (王海波), WANG Hui (王慧), HUANG Lijuan (黄丽娟), and ZHANG Lijun (张丽君)
- Subjects
non-alcoholic fatty liver disease ,physical examination ,prediction ,young adults ,triglycerides ,非酒精性脂肪肝病 ,体检 ,预测 ,青年人群 ,甘油三酯 ,Nursing ,RT1-120 - Abstract
Objective To explore the risk factors of non-alcoholic fatty liver disease (NAFLD) in young adults and to establish a model for prediction, in order to provide reference for the early prevention of the disease in young people. Methods A retrospective analysis was performed on the young adults who underwent routine physical examination in the Department of Physical Examination from January 2018 to June 2022. Totally 365 adults with NAFLD were divided into the NAFLD group(observation group), and 273 healthy adults were divided into the Healthy group (control group). The differences in general information and blood drawing results between the two groups were analyzed. Results The proportion of male, smoking and hypertension in the NAFLD group was significantly higher than that in the Healthy group; The mean values of BMI and low density lipoprotein-cholesterol in the NAFLD group were significantly higher than those in the Healthy group; The median values of triglyceride, total cholesterol, uric acid, alanine aminotransferase, aspartate aminotransferase and glycosylated hemoglobin in the NAFLD group were higher than those in the Healthy group, with significant difference(P<0. 05). Multivariate regression analysis showed that BMI increased (OR=1. 429; 95%CI=1. 306~1. 563; P=0. 001), triglyceride (OR=1. 524; 95%CI=1. 086~2. 137; P=0. 015), serum uric acid (OR=1. 005; 95%CI=1. 001~1. 008; P=0. 019), alanine aminotransferase (OR=1. 049; 95%CI=1. 026~1. 071; P=0. 001), aspartate aminotransferase (OR=0. 986; 95%CI = 0. 972~0. 999; P=0. 038), glycosylated hemoglobin (OR=7. 800; 95%CI=3. 666~16. 597; P=0. 001) were independent risk factors for NAFLD(P
- Published
- 2023
- Full Text
- View/download PDF