Search

目的 分析2013—2023年缺血性卒中和睡眠相关性研究的现状及研究热点。 方法 在Web of Science核心合集中检索2013年1月1日—2023年12月31日缺血性卒中和睡眠相关性研究的文献。使用RStudio的bibliometrix软件包和VOSviewer软件对该领域研究的发文量、国家/地区、机构、作者、期刊、文献引用、关键词和研究热点进行分析，并进行可视化呈现。 结果 共检索到798篇文献。以通信作者分析，中国发文199篇，居全球首位，且与多个国家建立了合作关系。美国发文196篇，位列第2。发文量最多的机构是加拿大多伦多大学，共34篇。发文量前10位的作者中5位来自美国密歇根大学，相互合作较密切，其中美国学者Devin L Brown发表文章数量为28篇，被引频次236次，发文量和被引频次均居首位。发文量最多的期刊是Sleep Medicine（74篇），发表文章被引频次最高的期刊是Stroke（3542次）。关键词可视化分析发现卒中与睡眠呼吸暂停出现频次最高。在卒中与睡眠相关性研究领域，研究主题分析提示失眠、抑郁作为基础课题对该领域发展非常重要，卒中预防、功能结局、脑血流主题研究需要努力开发。 结论 越来越多的研究聚焦于缺血性卒中和睡眠之间的关联性，中国和美国在该领域发表文献较多，睡眠呼吸障碍是主要研究热点。未来在卒中和睡眠领域可探索失眠、抑郁、卒中预防、功能结局、脑血流等主题。 Abstract: Objective To analyze the current status and research hotspots of research on the correlation between ischemic stroke and sleep from 2013 to 2023. Methods A literature search was conducted in the Web of Science core collection for articles related to ischemic stroke and sleep published between January 1, 2013, and December 31, 2023. The bibliometrix package in RStudio and VOSviewer software were utilized to analyze and visualize the number of published studies, contributing countries/regions, institutions, authors, journals, citations, keywords, and research hotspots in this field. Results A total of 798 articles were retrieved. An analysis of corresponding authors revealed that China ranked first globally with 199 publications and established collaborations with multiple countries. The United States followed closely with 196 publications. The University of Toronto (Canada) was the leading institution with 34 publications. Among the top ten authors, five were from the University of Michigan (US), and they had close cooperation with each other. American scholar Devin L Brown published 28 articles and was cited 236 times, ranking first in the number of articles published and the frequency of citations. Sleep Medicine published the most articles on ischemic stroke and sleep (74 articles), while Stroke had the highest citation frequency (3542 times). Through the visual analysis of keywords, it was found that stroke and sleep apnea had the highest occurrence frequency. In the research field of the correlation between stroke and sleep, the analysis of research themes suggests that insomnia and depression are fundamental topics crucial to the development of this field. Stroke prevention, functional outcomes, and cerebral blood flow are potential themes that require further exploration. Conclusions An increasing number of studies have focused on the correlation between ischemic stroke and sleep. China and the United States have published more literature in this field, and sleep-disordered breathing is the major research hotspot. Future research in the field of stroke and sleep should explore themes such as insomnia, depression, stroke prevention, functional outcomes, and cerebral blood flow.

血管性认知障碍患者往往伴有睡眠障碍，睡眠的紊乱进一步降低了患者的生活质量，增加了其脑血管事件的风险，也加重了照料者的负担。有效治疗患者的睡眠障碍不仅可以改善其生活质量，对患者的认知及功能康复也有积极影响。本文对血管性认知障碍患者常见的睡眠紊乱进行综述，着重阐述了睡眠障碍非药物治疗方面的研究成果，并对这些治疗方法未来的研究方向以及在血管性认知障碍患者中的应用前景进行了探讨。 Abstract: Patients of vascular cognitive impairment often suffered from all kinds of sleep problems, which further reduced their quality of life, improved risk of cerebrovascular events and increased their caregiver’s burden. Effective treatment of sleep disorders can not only improve the quality of life of patients, but also have positive effects on the cognitive and functional rehabilitation of patients. In this article, we reviewed the common sleep problems in patients of vascular cognitive impairment, elaborated on the present research results of non-pharmacological treatments to these problems, and discussed the future research fields and application prospects of non-pharmacological therapy for sleep disturbance of vascular cognitive impairment patients.

目的 评估绝经激素治疗与卒中发生之间的相关性。 方法 计算机检索PubMed、Embase和Cochrane图书馆从建库到2022年1月5日已经发表的关于绝经后女性采取绝经激素治疗的随机对照试验以及观察性研究，其中随机对照试验治疗方式必须为口服激素治疗，且随访的时间应超过6个月。探索绝经激素治疗与卒中之间的相关性，结局指标为研究人群的卒中发生率。 结果 绝经激素治疗随机对照试验的meta分析纳入了7项研究，35 776例健康女性中共有566例（1.58%）发生卒中，接受绝经激素治疗的18 337例健康女性中共有332例（1.81%）发生卒中，对照组17 439例中共有234例（1.34%）发生卒中，绝经激素治疗的健康女性卒中发病率是对照组的1.40倍（RR 1.40，95%CI 1.19～1.65）。绝经激素治疗观察性研究的meta分析纳入了3项研究，167 770例女性中共有1425例（0.84%）发生卒中，接受绝经激素治疗的61 117例女性中共有513例（0.84%）发生卒中，对照组106 653例女性中共有912例（0.86%）发生卒中，绝经激素治疗组与对照组之间差异无统计学意义（RR 0.96，95%CI 0.86～1.07）。 结论 绝经激素治疗与卒中发生之间可能无明显的相关性。 Abstract: Objective To evaluate the association between menopausal hormone therapy and stroke. Methods The PubMed, Embase and Cochrane Library were retrieved for randomized controlled trials (RCTs) and observational studies on menopause hormone therapy for postmenopausal women published from inception to January 5, 2022. The treatment in RCTs must be oral hormone therapy, and the follow-up time should be over 6 months. The outcome was the incidence of stroke in the subjects of the included studies. The association between menopausal hormone therapy and stroke was analyzed. Results The meta-analysis of RCTs included 7 studies including 35 776 healthy women, and stroke occurred in 566 women (1.58%). Of 18 337 healthy women who received menopausal hormone therapy, stroke occurred in 332 women (1.81%). In the control group, stroke occurred in 234 (1.34%) among 17 439 healthy women. The incidence of stroke in healthy women who received menopausal hormone therapy was 1.40 times higher than that in those who did not receive menopausal hormone therapy (RR 1.40, 95%CI 1.19-1.65). The meta-analysis of observational studies on menopausal hormone therapy showed that 1425 (0.84%) stroke occurred in 167 770 women from 3 studies. Stroke occurred in 513 (0.84%) of 61 117 women receiving menopausal hormone therapy and 912 (0.86%) of 106 653 women in the control group, and there was no statistical difference in the incidence of stroke between the menopausal hormone treatment group and the control group (RR 0.96, 95%CI 0.86-1.07). Conclusions There may be no significant association between menopausal hormone therapy and stroke.

褪黑素具有显著抗衰老作用,其主要机制包括自由基清除和线粒体保护，褪黑素水平的下降可能是人体衰老的表现。此外，研究证实褪黑素具有降脂、降压和减重作用，可预防和延缓动脉粥样硬化进展，改善脑缺血再灌注损伤，在缺血性卒中领域具有良好的应用前景。本文对褪黑素抗衰老、预防卒中相关危险因素和改善卒中预后等方面的作用机制和应用前景进行总结。 Abstract: Melatonin has significant anti-aging effect, and the main action mechanisms includes free radical scavenging and mitochondrial protection. The decline of melatonin level may be the manifestation of human aging. In addition, it has been confirmed that melatonin has the effect of lipid-lowering, antihypertension and weight-loss, which can prevent and delay the progression of atherosclerosis, and reduce ischemia-reperfusion injury, so melatonin has a good application prospect in the field of ischemic stroke. This article summarized the mechanism and application prospect of melatonin in anti-aging, preventing stroke related risk factors and improving stroke prognosis.

Copyright of Chinese Journal of Stroke is the property of Chinese Journal of Stroke Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 了解神经病学专业硕士研究生对睡眠专业知识的掌握现状,探讨在带教过程中的知识传播重点。 方法 对首都医科大学附属北京天坛医院2021年在读的神经病学硕士研究生50人，开展轮转睡眠中心前后的睡眠医学知识问卷调查并比较轮转前后的差异。 结果 神经病学硕士研究生在轮转睡眠中心前对失眠的非药物治疗方式、评估方法、指南等专业知识的知晓率较低，其中对经颅直流电刺激治疗失眠、睡眠时间与卒中风险的曲线关系这两方面知晓程度最低，分别为2%和10%。经过1个月的轮转学习后，研究生对睡眠障碍专业知识的知晓程度显著提升，与轮转前相比，除音乐和芳香疗法的知晓程度差异未达到统计学意义外，其他知识点的知晓率差异均有统计学意义。 结论 神经病学专业硕士研究生对睡眠专业知识的知晓率偏低，短期的临床教学即可弥补其睡眠医学知识短板。 Abstract: Objective To understand the current status of neurology graduate students on sleep medicine knowledge, and to discuss the critical teaching knowledge in clinical teaching. Methods A questionnaire survey on sleep medicine was conducted on 50 neurology graduate students in Beijing Tiantan Hospital, Beijing Medical University in 2022 before and after their rotation to the Sleep Center. The differences in sleep medicine knowledge between before and after their rotation were compared. Results The awareness rates of non-drug treatments evaluation methods, and guidelines of insomnia for neurology graduate students were relatively low before rotation, with the lowest rates of transcranial direct current stimulation for insomnia at 2% and the curvilinear relationship between sleep duration and stroke risk at 10%. After the 1-month rotation, the degree of mastering the knowledge of sleep disorders for neurology graduate students were significantly improved. The differences in awareness rates of the other knowledge except for music and aromatherapy between before and after the rotation were statistically significant. Conclusions The awareness rate of professional knowledge of sleep medicine among graduate students in neurology was low. Short-term clinical teaching can make up for the deficiency of sleep medicine knowledge.

Copyright of Chinese Journal of Stroke is the property of Chinese Journal of Stroke Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

[Objective]A rhizobacterium with salt-resistant and growth-promoting effects was screened from the saline-alkali soil in Yellow River Delta to prepare an agent for alleviating high-salt stress of maize seedlings.[Method]The salt-resistant and growth-promoting functions of the strain were identified on functional mediums, and the species of the strain was determined by 16S rDNA sequence and whole genome analysis. The strain was applied to maize rhizosphere to verify the salt-resistant and growth-promoting effects of the strain on maize seedlings.[Result]A strain Bacillus atrophaeus CNY01 was screened from the saline-alkali soil of Yellow River Delta. Strain CNY01 grew normally under the condition of 0-16% NaCl and pH 5-8. Strain CNY01 had the ability of degrading protein and dissolving potassium, and inhibited the growth of plant pathogens such as Ralstonia solanacearum and Fusarium moniliforme. The application of strain CNY01 promoted the growth of maize seedlings under high-salt condition and alleviated the stress of high salt on maize seedlings. When strain CNY01 was applied to maize seedlings in nutrient solution containing 100 mmol/L NaCl for 8 d, the physiological plant height, root length, and fresh weight of maize seedlings increased by 38.80%(P<0.01), 23.73%, and 28.19%(P<0.01), respectively. When strain CNY01 was applied to maize seedlings in pot experiments adding 100 mmol/L NaCl for 28 d, the physiological plant height, the aboveground fresh weight, and the underground fresh weight of maize seedlings increased by 10.84%, 41.87%(P<0.01), and 23.29%, respectively. Genes that maintain cell osmotic pressure and synthesize stress proteins to alleviate high salt stress were also predicted in the genome sequence of this strain.[Conclusion]A strain of B. atrophaeus CNY01 is screened from saline-alkali soil of Yellow River Delta, which has the function of preventing disease and promoting growth, and has significant salt-resistant and promoting growth effect on maize plants. Meanwhile, strain CNY01 contains genes related to salt-resistant and growth-promoting. B. atrophaeus CNY01 is an important strain resource. [ABSTRACT FROM AUTHOR]

Copyright of Mechanical & Electronic Control Engineering is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 探讨颅内外动脉粥样硬化的相关因素是否存在差异。 方法 在中国颅内动脉粥样硬化研究的数据库中，将患者分为4组：无显著颅内外动脉狭窄或闭塞组、 单纯颅内动脉病变组、单纯颅外动脉病变组及颅内合并颅外动脉病变组。以无显著颅内外动脉狭窄 或闭塞组作为参考，应用多元Logistic回归分析，评估颅内外动脉病变的相关因素。 结果 共入组2864例缺血性脑血管病患者，其中无显著颅内外动脉狭窄或闭塞组1388例（48.5%）、 单纯颅内动脉病变组1074例（37.5%）、单纯颅外动脉病变组141例（4.9%）、颅内合并颅外动脉 病变组261例（9.1%）。多因素分析显示，单纯颅内动脉病变的独立相关因素包括：白质病变[比值比 （odds ratio，OR）1.359，95%（confidence interval，CI）1.109～1.666，P =0.0031] 、白细胞计数（OR 1.045， 95%CI 1.007～1.084，P =0.0210）、空腹血糖（OR 1.054，95%CI 1.009～1.101，P =0.0182）、高密度脂 蛋白（OR 0.644，95%CI 0.480～0.864，P =0.0034）；单纯颅外动脉病变的独立相关因素包括：高龄 （OR 1.047，95%CI 1.026～1.069，P

目的 分析大脑中动脉（middle cerebral artery，MCA）分布区非心源性缺血性卒中患者的临床和影像 学特征及复发的危险因素。 方法 连续入选发病7 d以内的MCA分布区非心源性缺血性卒中患者。收集患者的人口学信息、血管 病的危险因素和发病时的主要症状及体征，评价患者的头颅磁共振影像包括急性梗死灶的部位、 数量、分布特征、责任动脉有无狭窄、缺血性卒中的病因分型。随访患者1年内有无缺血性卒中或短暂 性脑缺血发作（transient ischemic attack，TIA）复发，通过多元Logistic回归分析患者复发的危险因素。 结果 研究共入组926例患者，责任MCA狭窄≥70%的患者（447例）常见多发梗死灶（338例，75.6%） 和分水岭梗死（317例，70.9%），而责任MCA无狭窄或狭窄程度

目的 分析非心源性缺血性卒中患者1年复发的危险因素。 方法 连续入选1978例发病7 d内的非心源性缺血性卒中患者。收集患者的人口学信息、血管病危险 因素和发病时的主要症状及体征，评价患者的头颅磁共振成像结果，包括梗死灶的部位、数量、急 性梗死灶的分布特征及责任动脉、责任动脉有无严重狭窄、缺血性卒中的病因分型。随访患者1年内 有无缺血性卒中或短暂性脑缺血发作（transient ischemic attack，TIA）的复发，通过多元Cox回归分析缺 血性卒中患者复发的危险因素。 结果 95例(4.8%)患者1年内缺血性卒中或TIA复发。冠状动脉粥样硬化性心脏病病史、缺血性卒中病 史、缺血性卒中发病前3个月内反复TIA、责任脑动脉狭窄程度≥70%和后循环缺血性卒中是1年内复发 的危险因素。 结论 后循环梗死、有责任脑动脉严重狭窄及缺血性心脑血管病病史的非心源性缺血性卒中患者复 发的风险较高。 Abstract: Objective To investigate the risk factors of noncardiogenic ischemic stroke (IS) recurrence at 1 year after onset of IS. Methods A total of 1978 noncardiogenic IS patients with onset of symptoms

Copyright of Agricultural Archaeology is the property of Agricultural Archaeology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Stroke is the property of Chinese Journal of Stroke Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Multi-label answer aggregation problem aims to estimate the ground truth labels of samples by aggregating a large number of non-expert annotations collected by crowdsourcing. Due to the high annotation cost, multiple sample categories and uneven distribution of digital cultural heritage data, it brings great challenges to multi-label answer aggregation of datasets. Previous methods mainly focused on single-label problems, ignoring the label relevance of multi-label tasks; To some extent, most multi-label aggregation methods consider label correlations but are sensitive to noises and outliers. To solve these problems, this paper proposed a multi-label answer aggregation method based on adaptive graph regularization and joint low rank matrix factorization AGR-JMF. Firstly, it divided the input annotation matrix into two parts: pure annotations and noise annotations; Then, it constructed the association matrix between labels by adaptive graph regularization method for pure annotations; Finally, to realize the multi-label answer aggregations, it used labeling quality, label relevance, and the behavior attributes similarity between annotators to guide the low rank matrix factorization. Experiments on real-world datasets and MGF dataset show that AGR-JMF has obvious advantages over existing algorithms in terms of aggregating accuracy and identifying unreliable annotators. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Mental Health Journal / Zhongguo Xinli Weisheng Zazhi is the property of Chinese Mental Health Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

For the reasons of the vast territory and abundant species resources, fish remains are one of the most common animal remains in China. On the premise of a relatively small number of overall studies on fish compared with mammals, there are some kinds of monographic studies on fish remains including species identification, bone surface modifications, reconstruction of size, estimation of meat yield, inference of fishing gears and environmental reconstruction etc. But studies on the validation of dead age are even more relatively sparser and research materials are mainly skeletal elements such as spines, opercular series, scales and fin rays etc. Otolith is consisted of calcium carbonate which continuously deposited and immersed in the labyrinth endolymph. Relatively isolated environment, annual periodicity and continuity of sedimentation make otolith become a kind of ideal materials on age validation. Moreover, age validation and aging method comparisons have been examined for nearly a century by now and a great quantity of results indicate that otolith has obvious superiority over other skeletal elements in aging individuals and the application of such aging method in Archaeology has been much more and more general. This passage will make efforts to introduce otolith especially its value in age validation and will be going to start with three aspects including brief research history on age validation of fish, basic features and method of retrieving of otolith and basic method of age validation on otolith. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Mental Health Journal / Zhongguo Xinli Weisheng Zazhi is the property of Chinese Mental Health Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Ecology & Rural Environment is the property of Journal of Ecology & Rural Environment Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Endometrial receptivity (ER), one of important factors related to the successful implantation of embryo, refers to the ability of endometrium to accept the embryo. Benifited from the development of assisted reproductive technology, the number of high-quality embryos has increased. However, the success rate of embryo implantation has not reached a high level. Most studies on the implantation process are focused on embryo, while the study on endometrial factors is less. It is necessary to pay attention to ER, and how to improve ER, so as to improve the embryo implantation rate and the clinical pregnancy rate. Heparin as an anticoagulant plays an important role in anticoagulant, inhibition of platelet aggregation and anti-inflammation. Heparin was also widely used in the field of obstetrics and gynecology, such as the prevention of postoperative thrombosis and recurrent abortion, and the treatment of gestational hypertension and other diseases. In addition, heparin has also been used to improve the success rate of embryo implantation in the clinical practice of reproductive medicine due to its positive effect on ER. The clinical application of heparin in reproductive medicine, as well as the mechanism related to ER, was reviewed. [ABSTRACT FROM AUTHOR]

Copyright of Southwest China Journal of Agricultural Sciences is the property of Editorial Department of Southwest China Journal of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Mental Health Journal / Zhongguo Xinli Weisheng Zazhi is the property of Chinese Mental Health Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Southwest China Journal of Agricultural Sciences is the property of Editorial Department of Southwest China Journal of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to carry out more comprehensive accident analysis and prevention work via accident causation model 24Model, the authors analyze the relationship between hazards and accidents. Then the system characteristics of 24Model is expounded. The study shows that the hazards are the sources of the accident which equates to the accident causations. 24Model is a systematic accident causation model which involves features of integrity, relevance, hieraichy and dynamic. The characteristics of integrity, relevance, hierarchy and dynamic of 24Model are illustrated with an example which is the capsized accident of the "Eastern Stax" ferry analyzed via 24Model. [ABSTRACT FROM AUTHOR]