Search

Copyright of China Condiment is the property of China Condiment and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Condiment is the property of China Condiment and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

随着现代信息技术的飞速发展,社会的发展促进了教育的改革,国内外众多高校在教学改革道 路上不断实践,纷纷开始实施网络课堂教学的新模式。小规模限制性在线课程(SPOC)是在慕课(MOOC)基础 上发展而来的一种新兴的教学模式,其既融合了在线教育的优点,同时也可弥补传统教学方法的缺陷,让在线 教育与传统的教学模式融合,突出“以学生为中心”的新型教育理念。该文构建了SPOC教学模式,并运用在神 经病学教学中,详细论述 SPOC教学模式具体的应用过程,证实了SPOC教学模式适用于神经病学课程。在神 经病学教学中,进行SPOC混合教学模式试点,旨在为高等医学院校在教学实践中应用SPOC教学模式提供范 例和支持,为今后的神经病学教学提供有益的启迪。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Shenyang Pharmaceutical University is the property of Shenyang Pharmaceutical University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To discuss the protective effect of fructus mume total flavonoids(FMF) on the injury of the SH-SY5Y cells induced by 1-methyl-4-phenylpyridinium（MPP+) through regulating microRNA(miR)-145-3p expression, and to clarify the mechanism. Methods The SH-SY5Y cell model of Parkinson’s disease(PD) was established by MPP+ induction. The optimal intervention concentration and action time of MPP+ and FMF were screened out by CCK-8 assay. The cells were divided into control group(untreated), model group(treated with 500 μmol·L-1 MPP+ for 24 h), MPP++mimics group(transfected with miR-145-3p mimics), MPP++NC group(transfected with miR-145-3p NC), MPP++FMF group treated with 0.25 g·L-1FMF for 24 h), MPP++mimics+FMF group(transfected with miR-145-3p mimics and treated with 0.25 g·L-1 FMF for 24 h), and MPP++NC+FMF group(transfected with miR-145-3p NC, and(treated with 0.25 g·L-1 FMF for 24 h). CCK-8 assay was used to detect the proliferation abilities of the cells in various groups； Annexin Ⅴ-FITC/PI staining was used to the detect the apoptotic rates of the cells in various groups； transmission electron microscope was used to observe the ultrastructure morphology of mitochondrial autophagy in the cells in various groups； real-time fluorescence quantitative PCR(RT-qPCR) method was used to detect the expression levels of miR-145-3p in the cells in various groups； Western blotting method was used to detect the expression level of Beclin-1 protein and the ratio of LC3-Ⅱ/ LC3-Ⅰ in the cells in various groups. Results After treated with different concentrations of MPP+, the proliferation ability of the cells was significantly decreased（P<0.01), and the PD cell model was successfully constructed. The optimal concentrations and action time of MPP+ and FMF intervention were 500 μmol·L-1, 24 h, and 0.25 g·L-1 24 h, respectively.The CCK-8 assay results showed that the proliferation ability of the cells in model group was significantly lower than that in control group(P<0.01)； the proliferation abilities of the cells in MPP++mimics group and MPP++FMF group were significantly higher than that in model group（P<0.01)； the proliferation ability of the cells in MPP++mimics+FMF group was significantly higher than that in MPP++FMF group(P<0.01). The Annexin V-FITC/PI staining results showed that the apoptotic rate of the cells in model group was significantly higher than that in control group(P<0.01)； the apoptotic rates of the cells in MPP++mimics group and MPP++FMF group were significantly lower than that in model group(P<0.01)； the apoptotic rate of the cells in MPP++mimics+FMF group was significantly lower than that in MPP++FMF group(P<0.01). The transmission electron microscope results showed that the cells in control group showed the uniform and intact mitochondrial morphology, the cells in model group showed the enlarged and irregular mitochondria with vacuolar changes, and the cells in MPP++mimics group and MPP++FMF group showed the improved mitochondrial structure, compared with model group, the autophagosome numbers of the cells in MPP++mimics group and MPP++FMF group were increased； the cells in MPP++mimics+FMF group showed more intact mitochondrial structure, compared with MPP++FMF group, the autophagosome numbers in the cells was increased. The RT-qPCR results showed that the expression level of miR-145-3p in the cells in model group was significantly lower than that in control group(P<0.01)； the expression levels of miR-145-3p in the cells in MPP++mimics group and MPP++FMF group were significantly higher than that in model group(P<0.01)； the expression level of miR-145-3p in the cells in MPP++mimics+FMF group was significantly higher than that in MPP++FMF group(P<0.01).The Western blotting results showed that the expression level of Beclin-1 protein and the ratio of LC3-Ⅱ/LC3-Ⅰ in the cells in model group were lower than those in control group(P<0.05)； the expression level of Beclin-1 protein and the ratio of LC3-Ⅱ/ LC3-Ⅰ in the cells in MPP++mimics group and MPP++FMF group were significantly higher than those in model group(P<0.01)； the expression level of Beclin-1 protein and the ratio of LC3-Ⅱ/ LC3-Ⅰ in the cells in MPP++mimics+FMF group were significantly higher than those in MPP++FMF group(P<0.01). Conclusion FMF may promote the autophagy, alleviate the mitochondrial dysfunction, and attenuate the injury of the SH-SY5Y cells induced by MPP+, and its mechamism is related to upregulating the miR-145-3p expression. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Practical Medicine / Shiyong Yixue Zazhi is the property of Journal of Practical Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective： To analyze the effective chemical components and their action targets of epimedium in the treatment of hypothalamus-pituitary-adrenal gland/gonad/thyroid gland axis functional damage by using network pharmacology and molecular docking technology, and to preliminarily clarify its mechanism. Methods The effective chemical components and their corresponding target proteins of epimedium were screened by Traditional Chinese Medicine Systems Pharmacology (TCMSP) Database and Analysis Platform combined with the relevant literatures, and the Uniprot Database was used to standardize the target protein informations to get the corresponding standard gene names; the relevant target genes of hypothalamus-pituitary-adrenal gland/gonad/thyroid gland axis function damage were collected from the GeneCards Database and DisGeNET Database；the network of the relationship between the effective chemical components of the epimedium and their action targets was constructed by Cytascape 3.7.1 Software; the protein-protein interaction (PPI) network diagram of drug-disease of effective chemical components and target proteins of hypothalamus-pituitary-adrenal gland/gonad/thyroid gland axis function damage was constructed by STRING Database. Gene Ontology (GO) functional enrichment analysis and Kyoto Encyclopedia of Genes and Genome (KEGG) signaling pathway enrichment analysis were performed by OmicShare Database；molecular simulation docking and visualization were done by Pymol Software and the Autodock Tools Software. Results A total of 27 effective chemical components and 217 corresponding action targets of epimedium, and 465 target genes of hypothalamus-pituitary-adrenal gland/gonad/thyroid gland axis function damage were screened out, of which 62 target genes were closely related to the treatment of hypothalamus-pituitary-adrenal gland/gonad/thyroid gland axis function damage by epimedium.Quercetin，luteolin，kaempferol, and icariin and so on were the key effective chemical components, and the key target proteins were Cysteine protease 3 containing cysteine (Caspase-3), interleukin-6 (IL-6), oligosaccharides (FOS), tumor necrosis factor (TNF), hypoxia inducible factor-1 alpha (HIF1A), vascular endothelial growth factor A (VEGFA), interleukin-1β (IL-1β), estrogen receptor 1 (ESR1) ，recombinant prostaglandin endoperoxide synthase 2 (PTGS2), matric metallopeptidase 9 (MMP-9) ，and so on.The KEGG signaling pathway enrichment analysis results showed that the common targets were mainly concentrated in the pathways related to immune inflammation, hormone regulation, and energy metabolism. The molecular docking results showed that the potential active components of epimedium had a good affinity with IL-6, PTGS2, aldose reductase (AR), and mitogen-activated protein kinase 1 (MAPK1) targets. Conclusion Epimedium may play a potential therapeutic role in the treatment of hypothalamus-pituitary-adrenal gland/gonad/thyroid gland axis function damage in the aspects of anti-inflammatory immunity, hormone regulation, and energy metabolism through multiple targets and pathways. [ABSTRACT FROM AUTHOR]

Copyright of University Chemistry is the property of Peking University, College of Chemistry & Molecular Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Nanjing Medical University: Natural Sciences is the property of Journal of Nanjing Medicial University (NMU) Medical Publications Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Wildlife / Yesheng Dongwu Xuebao is the property of Chinese Journal of Wildlife Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electric Power is the property of Electric Power Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Nanjing Medical University: Natural Sciences is the property of Journal of Nanjing Medicial University (NMU) Medical Publications Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Changzhou University (Natural Science Edition) / Changzhou Daxue Xuebao (Ziran Kexue Ban) is the property of Editorial Department of Journal of Changzhou University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aiming at the defects that traditional spatial least significant(LSB)image hiding algoritm has poor robustness and obviously visual differences when the amount of embedded secret information is large, a spatial algorithm combining the most significant bits and human visual system is proposed.The most significant bit sequence optimization algorithm is used to match and replace the most significant bits of the carrier image to reduce the space occupied by the secret information. The human visual system is used to construct the information embedded depth table, and the secret information is embedded according to the different degrees of the embedded depth table. The MATLAB development environment is used to simulate several common attacks on hidden images. Experiments show that the algorithm has good robustness, embedding capacity and invisibility. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Computational Mechanics / Jisuan Lixue Xuebao is the property of Chinese Journal of Computational Mechanics Editorial Office, Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Pulp & Paper is the property of China Pulp & Paper Magazines Publisher and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to efficiently solve the shading problem between the upper layer and lower layer in the same cultivation system and between adjacent cultivation systems in multi-layer stereo-cultivation of strawberry, and to improve the fixed A-shaped frame system, a novel sun-tracking cultivation system was developed, which could keep the line of cultivation frame parallel to sunray to make the best use of direct light. In this study, some instruments, including the CANUOL intelligent remote control door opener, supporting multi-function controller, and the time control switch, were installed on the fixed A-shaped frame. So the fixed frame could rotate about its central axis according to a preset procedure, and the door opener revolved through the multi-function controller operation, thus boosting the cultivation frame motion. Time controller may set the start time of cultivation shelf running, running times, running time interval and the time length of operation as cultivation shelf homing according to the different needs of different seasons. The operating parameters of the cultivation frame were determined according to the changes of solar elevation and azimuth of the sun in winter in Beijing, based on the characteristics of the light environment of Beijing. This test set the running time of the sun-tracking frame to be 9: 00-16: 00 every day from November 2015 to March 2016, rotating once every 55 min, and turning 9 times every day. In November and next February and March, the total daily movement angle was 103.5°, each rotation angle was 11.5°, and each exercise took 4 s; the total daily movement angle was 96°, each rotation angle was 10.5°, and each exercise took 3.6 s in December and January next year. Parameters could be adjusted according to the actual situation in the process of actual production and application. In this study, the strawberry planting time was September 8th, 2015, and the harvest time was from January 13th to March 17th, 2016. Experimental design was that 5 sun-tracking frames were set as the test group, and 5 fixed frames were as a control group; then the difference between the 2 light environments was compared, and the temperature of canopy and root, the yield and the profit of strawberry were used to validate whether the sun-tracking frames could improve light environment and increase the production. Results showed that integrated photosynthetic photon flux density (PPFD) of sun-tracking system was higher than that of fixed system on both middle and lower layers. Within 3 months of winter, compared with fixed system, integrated PPFD on upper, middle and lower layer of sun-tracking system increased by 28.0%, 79.3% and 38.6% respectively in the east side and 30.1%, 41.0% and 18.2% respectively in the west side. So, the sun-tracking frame could change the light-shielding. The strawberry canopy and rhizosphere temperature of the sun-tracking cultivation were better than the fixed stereo cultivation frame, and the minimum value of the cultivated strawberry rhizosphere temperature of fixed frame at each layer was lower than the sun-tracking cultivation frame. Meeting the most suitable rhizosphere temperature of 15-20°C for upper, middle and lower layer of west side, the time of the sun-tracking cultivation frame was 60, 40 and 120 min longer than the corresponding position of the fixed cultivation frame, respectively. Accordingly, the time of the former canopy temperature below 5°C was 130, 170, 230 min shorter than the latter, respectively. The strawberry yield per plant on sun-tracking frame was higher than the corresponding position on fixed frame. During the trial, compared with the fixed system, the strawberry output of the sun-tracking system was increased by 214.8 kg/667 m2. Benefits were increased by 6 498.5-12 942.5 yuan. So, the sun-tracking system can improve the light and temperature environment condition, which promotes the output of strawberry and benefit. Therefore, it is valuable cultivation technology and should be widely applied. [ABSTRACT FROM AUTHOR]

In the process of facility horticulture cultivation, the model of three-dimensional cultivation has been paid more and more attention. “H” type cultivation frame is widely used in stereo-cultivation of strawberry at present. In practical applications, growers choose the different layers of cultivation for planting. The most common arrangement of planting frame is two or three layers, which way can reduce the costs with higher yields and benefits, we do not know now. Therefore, an experiment aimed to select a better combination of cultivation frame was performed in this study. In this experiment, three combinations of “H” type cultivating shelves were set up, namely, two-layer frames arranged adjacently (T1), two-layer frame and three-layer frame are alternately arranged (T2), three-layer frames are arranged adjacently(T3), to compare the light conditions, growth status and yield differences. The experiment was carried out in a solar greenhouse in Changping district of Beijing from August 2015 to April 2016. The length of the greenhouse is 100 m and the span is 8 m. Strawberry varieties is “Hong Yan”, planting date was August 29, 2015. Photosynthetic photon flux density (PPFD) of strawberry canopy and growth index were measured during the trial. Growth index include strawberry plant height and leaf chlorophyll relative content (SPAD), strawberry yield per plant, the number of fruits per plant, the average weight of fruit. Measured production time was three months. Results showed that under T1 treatment, the strawberries light conditions were the best of the upper and lower cultivars. During the experiment, the trend of light curves of the three cultivars in T2 and T3 were basically the same, but PPFD of the upper, middle and lower layers in T2 were higher than that in T3 corresponding position. During the experiment, the time length that light intensity at strawberry canopy reached light saturation point (LSP) of T2 upper layer was longer than that of T3 corresponding position; the time length of T2 middle layer reached the strawberry LSP was 240 min, and that of T3 middle layer was always below the LSP. In addition, the light intensity at strawberry canopy in the lower layer of T2 reached light compensation point was 230 min, and that of T3 lower layer was always below the light compensation point (LCP) all day. During the experiment, the time length that light intensity at strawberry canopy reached the LSP within two days of T1 and T2 were calculated, results showed that the time length reached LSP in T1 upper layer increased by 40% compared with that of T2. The time length of reaching at LSP in lower of T1 and T2 was 100 min and 0 min, respectively. The time length of reaching the LCP in the upper, lower layers of T1 increased by 9.3%, 21.4% compared with that of T2, respectively. Thus, the light environment of T1 was better than that of T2. Growth index of T1 strawberry was the best, yield per plant and the number of fruits per plant in T1 was higher than that of other treatments. Correlation indexes of strawberry yield were the worst in T3. During the test period, the yield per unit area of T1 was 50.8 kg, and the cost of T1 was the lowest in three treatments, yield per unit area of T1 was increased by 2.8%, 33.7% compared with that of T2 and T3, respectively. Therefore, strawberries of all two layers arrangement of “H” type cultivation frame got better lighting conditions, reduced costs and obtained better economic benefit. All two layers arrangement of “H” type cultivation frame (T1) was suitable for application in actual production. [ABSTRACT FROM AUTHOR]

This paper summarized the integrated traditional Chinese and western medicine in wound care of a patient with erysipelas of lower limbs. Based on the comprehensive nursing assessment on dietary, mental status and infection risks of the patient, basic nursing interventions and Traditional Chinese Medicine nursing techniques such as blood-letting acupuncture, cupping and Tongbian scraping were carried out to unblock the main and collateral channels, create Qi and activate blood, thereby promoting chronic wound healing. (本文总结1例下肢丹毒患者破溃伤口的中西医结合护理经验。基于护理评估, 在常规饮食、情志、抗感染等护理基础上, 采用刺络、拔罐联合铜砭刮痧中医护理技术, 引邪出表、疏通经络、造气活血, 改善伤口及周围皮肤的气血运行, 有效促进患者慢性伤口的愈合。)