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为研究碗扣式钢管支撑架不同构造形式节点的转动刚度特性，提出测定支撑架体的角节点、边节点与中间节点转动刚度的试验方案，对应分别插入2根、3根和4根水平杆的节点转动刚度试验。在利用相应扣件式节点试验来验证本方案合理性的基础上，对当地市场随机采购的碗扣式钢管的弹性模量进行测定。采用三折线模型对碗扣式节点的M-θ曲线进行拟合，分析了不同水平杆数量对其转动刚度的影响及其破坏特点。研究结果表明：（1） 碗扣式钢管支撑架角节点、边节点的转动刚度分别为中间节点转动刚度的77.93%、92.14%，且均高于规范给出的建议值25 kN·m∙rad-1；角节点与边节点的转动刚度相对较弱，对架体整体稳定性的影响不可忽略；（2） 当地市场随机采购的碗扣式钢管的弹性模量较新构件有不同程度的下降，最大降幅约为30%；（3） 碗扣式节点的破坏先后顺序为水平杆、上碗扣、立杆和下碗扣；节点的破坏发生在水平杆接头处，应对此处加强质量监管。相关结论可为同类半刚性节点的转动刚度确定提供参考。

Copyright of Inorganic Chemicals Industry is the property of Editorial Office of Inorganic Chemicals Industry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Power Generation Technology is the property of Power Generation Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Multipurpose Utilization of Mineral Resources / Kuangchan Zonghe Liyong is the property of Multipurpose Utilization of Mineral Resources Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The automated intravenous drug dispensing device is an intelligent apparatus designed to imitate the manual dispensing process and realize the allocation of intravenous infusion drugs through corresponding program and mechanical structure. The application of the device accelerates the construction of smart hospitals, improves the efficiency and accuracy of intravenous drug allocation, and reduces the risk of occupational injuries to medical staff. However, compared with the widespread application of this device, there is a lack of up-to-date management consensus, the absence of unified standards, and the yet-unverified correctness of its surgery and safety of drug allocation, which may have potential clinical risks. In order to standardize the management and application of automated intravenous drug dispensing device, under the guidance of National Cancer Center ( NCC ) and in conjunction with multidisciplinary experts, the Clinical Pharmacy Branch of China International Exchange and Promotive Association for Medical and Health Care has formulated the Chinese Expert Consensus on Pharmaceutical Management of Intravenous Drug Automated Dispensing (2023) by adopting the Delphi method and the expert meeting method based on available evidence-based evidence, pharmaceutical administration-related laws and regulations, and pharmaceutical care practices in the field of clinical medication. The consensus expands and extends the connotation of pharmaceutical management of intravenous drug automated dispensing, which has constructed a comprehensive pharmaceutical management system, and provided a scientific basis for pharmacists to carry out pharmaceutical management of intravenous drug automated dispensing. [ABSTRACT FROM AUTHOR]

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Copyright of Multipurpose Utilization of Mineral Resources / Kuangchan Zonghe Liyong is the property of Multipurpose Utilization of Mineral Resources Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Industrial Minerals & Processing / Huagong Kuangwu yu Jiagong is the property of Industrial Minerals & Processing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Advanced Engineering Science / Gongcheng Kexue Yu Jishu is the property of Advanced Engineering Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the effect of astragaloside on the differentiation of bone marrow mesenchymal stem cells into pericytes^ ^^iods: The MSCs were isolated from SD rats (5d-7d) bone marrow by whole bone marrow primary culture method, purified by amplification in vitro, and the fourth and fifth generation were used in this study. The purified cells were divided into three groups: negative control group, incubated in L-DMEM with 15% FBS without drug intervention; positive control group,cultured with TGF-p1 5 ng/mL for 72 hour; Ast group, cultured with 4 滋g/mL Ast for 1 day, 2 day, 3 day, 5 day and 7 day; blocker group,inhibitor ofthe TGF-p1 type I receptor sb431542 being administered prior to Ast exposure,of which samples were collected at 1 day, 2 day, 3 day. Expression levels ofNG2, 琢-SMA were examined by RT-PCR and Western blot. The expression levels of p-Smad2 and Smad2/3 were examined by Western blot. Results: The mRNA and protein expression level of NG2, 琢-SMA was higher in all Ast group. The mRNA and protein expression level of NG2, 琢-SMA was higher in Ast 3d group, compared with the negative control group and the positive control group (p<0.05). The TGF-茁 1/Smad signaling was activated after Ast intervention. The p-Smad2 protein level increased by day 1, reached a maximum at day 3, and then decreased. The protein expression level of p-Smad2 was higher in Ast 3d group,compared with the Ast 0d group (p<0.01). The effect of the astragaloside is blocked by the inhibitor of the TGF-茁 1 type I sb431542 exposure, leading to the down-regulation ofthe mRNA and protein level ofNG2, 琢-SMA. Compared with the Ast group at the same time point, the mRNA and protein expression level of NG2, 琢-SMA reduced significantly in the blocker group at day3 (p<0.001). The signaling pathway was inhibited, as the p-Smad2 protein level decreased. Compared with the Ast 3d group, the protein expression level of p-Smad2 reduced significantly in the sb431542+Ast 3d group (p<0.001). Conclusion: Astragaloside can induce bone marrow mesenchymal stem cells differentiating into pericytes through the TGF-茁1/Smad2 signaling pathway. [ABSTRACT FROM AUTHOR]

Objective: To investigate the isolation, culture and identification methods of rat pulmonary microvessel pericytes RPMPC in the lung of SD rats. Methods: Using mechanical shear, type I collagenase digestion and micropore filtration combined with ultra high speed centrifugation to separate the rat pulmonary microvascular fragments; using medium (DMEM) containing 15% fetal bovine serum (FBS) to culture the RPMPCs; and using inverted microscope to observe the morphology and growth characteristics of RPMPCs. Detecting the expression of neuron glia antigen 2 (NG2), alpha smooth muscle actin (α-SMA), desmin (desmin) and CD31 antigen by the immunofluorescent methods; Detecting the expression of platelet-derived growth factor receptor beta (PDGFR- beta) by immunocytochemistry. The growth curve of pericytes was determined by CCK-8. The tube formation ability of the cells was detected by coculture with pericytes and endothelial cells. Results: The purity of RPMPC was high and could be passaged continuously. RPMPCs climb out after 48 hours of separation, with the shape of fusiform, triangular and irregular form. After 8 ~ 10d, the cells converge and grow as a palisade or vortex, without contact inhibition. In the early stage, a few endothelial cells were found, which were mononuclear or binuclear and rich in cytoplasm. PDGFR- beta, alpha -SMA, NG2 and desmin staining were positive, and CD31 staining was negative. The co culture of pericytes and endothelial cells leads to the formation of luminal structures. Conclusion: The pulmonary microvascular pericytes of higher purity can be obtained by this method, and the acquired cells have the characteristics and functions of pericytes. [ABSTRACT FROM AUTHOR]

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