Objective To retrospectively analyze the preoperative bone mineral density, bone metabolism index status, and osteoporosis treatment in patients with lumbar degenerative diseases. Methods The preoperative bone mineral density, bone metabolism index (including bone turnover markers, serum 250HD) detection status and osteoporosis treatment status of 516 patients with lumbar degenerative disease aged ~ 50 years old were recorded, and the bone mineral density was measured, Analyzed the relationship between bone density and age; for patients who perform bone metabolism index detection and bone density measurement at the same time, analyzed the relationship between bone density and bone metabolism index. Results Among 516 patients, a total of 139 (26.93%) bone mineral density tests were performed, Among them, 65 (46. 7 6%) had osteoporosis and 60 (43. 17%) had bone loss. There was a significant negative correlation between bone density and age (P < 0. 05).A total of 109 (21. 12%) patients were tested for bone metabolism indicators. The specific result were 39 patients (35.78%) with sufficient serum 250HD, 48 patients with insufficient serum 250HD (44. 04%), and 22 patients with deficiency (20. 18%).There was a negative correlation between serum 250HD and bone mineral density in male patients (r -= 0. 467, P -= 0. 021), while the correlation between serum 250HD and bone mineral density in female patients was not statistically significant. The correlation between bone turnover markers (13-CTX and P lNP) and bone mineral density was not statistically significant. Among 65 patients who were diagnosed with osteoporosis, 14 patients (21. 54%) were not treated with any medication, and 12 patients (18. 46%) were treated with basic calcium supplements and/ or ordinary vitamin D, 39 cases (60%) were treated for osteoporosis. Conclusion Patients with degenerative diseases of the lumbar spine have less osteoporosis evaluation before operation, The incidence of osteoporosis is high, the diagnosis rate is low, and the treatment rate is low. The author believes that atention should be paid to the detection of preoperative bone mineral density and bone metabolism in patients with lumbar degenerative diseases, and anti-osteoporosis treatment should be actively carried out. [ABSTRACT FROM AUTHOR]