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目的觀察丙泊酚、芬太尼靜脈全身麻醉復合局部麻醉在小兒包皮套扎術中的臨床應用效果。方法選取2013年7~12月在該院擇期行包皮套扎術的小兒60例,隨機分為全身麻醉復合局部麻醉組(研究組)和單純靜脈全身麻醉組(對照組),各30例。研究組患兒使用丙泊酚2 mg/kg、芬太尼3μg/kg單次靜脈推注誘導,患兒意識消失后再以1%利多卡因行患兒陰莖背神經阻滯麻醉后開始手術;對照組患兒使用丙泊酚2 mg/kg、芬太尼3μg/kg單次靜脈推注誘導,待患兒意識消失后開始手術。觀察兩組患兒手術期間心率(HR)、平均動脈壓(MAP)變化,全身麻醉藥用量、麻醉效果、復蘇時間及術后不良反應等。結果兩組患兒手術期間HR、MAP、麻醉效果比較,差異均無統計學意義(P>0.05)。研究組患兒復蘇時間明顯短于對照組,且呼吸抑制發生率、術后煩躁哭鬧和惡心嘔吐發生率及丙泊酚用藥量均明顯低于對照組,差異均有統計學意義(P<0.05)。結論丙泊酚、芬太尼靜脈全身麻醉復合局部麻醉在小兒包皮套扎術中是一種較為理想的麻醉方式,具有術中生命體征平穩,減少麻醉藥用量,術后麻醉蘇醒快等優點,能減少呼吸抑制、哭鬧躁動和惡心嘔吐等不良反應,達到安全舒適的效果。 [ABSTRACT FROM AUTHOR]