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Background Narrative exposure therapy (NET), an integration of narrative therapy and exposure therapy, has been shown to be effective in relieving the symptoms of post-traumatic stress disorder (PTSD), which can help patients gain a deeper understanding of their trauma and is also considered to be quite safe. PTSD is highly prevalent in children and adolescents, while the effectiveness of NET intervention varies among the subjects. Objective To systematically evaluate the effectiveness of NET for PTSD in children and adolescents, so as to provide references for the clinical application of NET. Methods On August 1, 2022, the Cochrane Library, PubMed, Web of Science, CINAHL, China National Knowledge Infrastructure (CNKI), SinoMed, VIP and Wanfang database were searched from their inception to June 2022. Search was conducted with the use of a combination of medical subject heading and free text terms, and randomized controlled trials relevant to NET for PTSD in children and adolescents were collected. Then the quality of the controlled trials was evaluated according to the Cochrane Collaboration's tool for assessing risk of bias (2011), and Meta-analysis was performed using RevMan 5. 4 software. Results Nine randomized controlled trials involving 394 children and adolescents with PTSD were included. Meta-analysis showed that NET and relaxation therapy reported comparable symptom relief in PTSD patients within 1 to 3 months after intervention (SMD=0. 22, 95% CI: -0. 84~1. 28) and at 6 months after intervention (SMD=0. 21, 95% CI: -0. 75~1. 17), while NET provided greater PTSD symptom relief than routine therapy both within 1 to 3 months after intervention (SMD=-0. 66, 95% CI: -1. 04~-0. 27) and at 6 months after intervention (SMD=-0. 77, 95% CI: -1. 36~ -0. 19), with statistically significant differences. Regarding the alleviation of depressive symptoms, the effect was similar between NET and routine therapy within 1 to 3 months after intervention (SMD=-0. 39, 95% CI: -0. 98~0. 21) and at 6 months after intervention (SMD=-0. 74, 95% CI: -2. 23~0. 75). No statistical difference was demonstrated between NET and routine therapy in relieving psychological distress (SMD=-0. 54, 95% CI: -2. 14~1. 07) and suppressing hyperorexia (SMD=-0. 17, 95% CI: -0. 54~0. 19)1 to 3 months after intervention. Conclusion NET yields a better outcome and a medium- and long-term effectiveness in alleviating symptoms of PTSD in children and adolescents compared with routine therapy, while it does not offer any significant advantages in improving depression symptoms, psychological distress and hyperorexia. [ABSTRACT FROM AUTHOR]

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目的 探讨影响食管癌患者术后机械通气时间的相关因素。 方法 选择食管癌术后入住 ICU 患者56 例，收集其性别、年龄、BMI,吸烟指数、合并症，肿瘤长径、部位、病理类型，术前外周血自细胞、血小板计数及血红蛋 自直蛋自、总蛋自、肌酐尿素氮、谷丙转氨酶、乳酸、动脉血氧分压以及手术时间。 选取入住 ICU后24 h 内急性生 理参数最差值，联合年龄、慢性健康情况进行急性生理与慢性健康状况 II (APACHE II )评分，统计患者ICU 机械通 气时间、总住院时间，术后肺部感染、手术部位出血情况，术后低血压需使用血管活性药物情况和冶疗预后情况，筛 选影响食管癌术后延迟撤机拔管的危险因素。 结果 根据术后24 h内是否成功撤机拔管，将食管癌术后入住 ICU 患者分为A组3 3 例和 B组23 例。 两组性别、年龄、BMI,吸烟指数、合并症，肿瘤长径、部位、病理类型以及术前实 验室检查资料比较差异均无统计学意义(P均 ＞0.05)。 A 组手术时间为(315.03 土87.28) min, B 组为(373. 83 土 101. 30) min, B组手术时间长于A组(t= 2. 321,P < 0. 05)。 B 组外周血自细胞计数和乳酸水平高于A组， 自蛋自 水平低于A组(P均<0.05)。 术后24 h 内 B组APACHE II评分高于A组(t=2. 854,P <0. 05)。 术后24 h内，A 组发生肺部感染 2 例、B组发生肺部感染 14 例，B组肺部感染发生率高于A 组(x² =19. 95,P<0.05)。 多因素 Logistic回归分析显示，术后乳酸水平升高、自蛋自水平降低及继发肺部感染是食管癌患者术后机械通气时间延长 的影响因素(P均 <0.05)。结 论 术后乳酸水平升高、自蛋自水平降低和继发肺部感染可导致食管癌患者术后撤 机拔管延迟，机械通气时间延长。 [ABSTRACT FROM AUTHOR]

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