Search

Copyright of Journal of Materials Engineering / Cailiao Gongcheng is the property of Journal of Materials Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electronic Components & Materials is the property of Electronic Components & Materials and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electronic Components & Materials is the property of Electronic Components & Materials and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electronic Components & Materials is the property of Electronic Components & Materials and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Electronic Components & Materials is the property of Electronic Components & Materials and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 探讨肺结核患者血清维生素A、视黄醇结合蛋白4(RBP-4)水平及其与肺结核耐药的关系。方法 根据痰液抗酸杆菌培养及药敏试验结果将427例肺结核患者(肺结核组)分为耐药者196例,非耐药者231例;另外选取100例体检健康者作为对照组。采用高效液相色谱法检测血清维生素A,采用ELISA法检测血清RBP-4蛋白。采用Logistic多因素回归分析法分析耐药的影响因素;采用受试者工作特征曲线(ROC曲线)分析血清维生素A和RBP-4蛋白水平预测肺结核患者耐药的价值。结果肺结核组耐药者及非耐药者血清维生素A和RBP-4蛋白水平均低于对照组,且耐药者均低于非耐药者,组间比较P均 <0.05; Logistic 多因素回归分析显示,年龄、BMI、维生素A和 RBP-4均是肺结核患者发生耐药的独立影响因素(P均<0.01)。ROC曲线分析显示,血清维生素A预测耐药的临界值为248.7μg/L,曲线下面积为0.956(95%CI:0.938~0.974),灵敏度为94.4%,特异度为85.7%;RBP-4蛋白预测耐药的临界值为7.4μg/m L,曲线下面积为0.850(95%CI:0.814~0.887),灵敏度为74.0%,特异度为86.2%。结论肺结核患者尤其是出现耐药者血清维生素A和RBP-4蛋白水平均降低,监测肺结核患者血清维生素A和RBP-4蛋白水平有助于预测耐药的发生。 [ABSTRACT FROM AUTHOR]