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Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer Engineering & Applications is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mycosystema is the property of Mycosystema Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Previous studies have found that cinnamaldehyde can promote the biological properties of osteoblasts in high glucose environment. OBJECTIVE: To observe the effect of cinnamaldehyde on proliferation and differentiation of osteoblasts under high glucose with electrospinning membrane as carrier. METHODS: The polycaprolactone membranes were prepared by electrospinning. MC3T3-E1 cells in logarithmic growth phase were divided into four groups: blank control group was added with high glucose medium. Polycaprolactone group was added with polycaprolactone membrane scaffold and high glucose medium. Drug group was added with high glucose medium containing cinnamaldehyde. Combined group was added with polycaprolactone membrane and high glucose medium containing cinnamaldehyde. CCK-8 method was used to detect cell proliferation and alkaline phosphatase kit was used to detect alkaline phosphatase activity at 1, 4 and 7 days of culture. RT-qPCR was used to detect the expression of osteocalcin mRNA at 7 days. RESULTS AND CONCLUSION: (1) CCK-8 assay showed that the cell proliferation of polycaprolactone group, drug group and combined group was faster than that of blank control group at each time point (P < 0.05). Cell proliferation of combined group was faster than that of polycaprolactone group and drug group at 4 and 7 days (P < 0.05), and cell proliferation of drug group was faster than that of polycaprolactone group at 4 and 7 days (P < 0.05). (2) The alkaline phosphatase activity of polycaprolactone group, drug group, and combined group was higher than that of blank control group at 4 and 7 days (P < 0.05). The alkaline phosphatase activity of combined group was higher than that of polycaprolactone group and drug group at 4 and 7 days (P < 0.05). The alkaline phosphatase activity of drug group was higher than that of polycaprolactone group at 7 days (P < 0.05). (3) The expression of osteocalcin mRNA in the four groups from high to low was the combined group, drug group, polycaprolactone group, and blank control group; there were significant differences between the two groups (P < 0.05). (4) Results suggest that polycaprolactone electrospinning membrane and cinnamaldehyde can promote the proliferation and differentiation of osteoblasts in high glucose environment. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effect of reduced glutathione combined with polyene phosphatidylcholine on liver function, liver fibrosis indexes and serum inflammatory factors in patients with acute drug-induced liver injury (ADILI). Methods: 100 patients with ADILI who were admitted in our hospital from January 2017 to March 2019 were selected, they were divided into control group and combination group by random stratified sampling method, 50 cases in each group. The control group was treated with polyene phosphatidylcholine, the combination group was treated with reduced glutathione combined with polyene phosphatidylcholine, the curative effect, liver function indexes [alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL) and glutamyltranspeptidase (GGT)], liver fibrosis indexes [laminin (LN), procollagen type III (PC-III), type IV collagen (IV-C), hyaluronidase (HA)], serum inflammatory factors [Interleukin-6 (IL-6), tumor necrosis factor -α(TNF-α), interleukin-2 (IL-2)] and adverse reactions were compared between the two groups. Results: The total effective rate of the control group was 79.00% (38 / 50), the total effective rate of the combination group was 94.00% (47/50), the total effective rate of the combination group was higher than that of control group (P<0.05). 4 weeks after treatment, the levels of ALT, AST, TBIL, GGT, LN, PC-III, IV-C, HA, IL-2, TNF-α, IL-6 in the two groups were decreased compared with those of before treatment, and the combination group was lower than the control group (P<0.05). There was no difference in the incidence of adverse reactions between the two groups during treatment (P>0.05). Conclusion: On the basis of polyene phosphatidylcholine, combined with reduced glutathione treat patients with ADILI, the curative effect is good, which can improve liver function and indicators of liver fibrosis, reduce the body's inflammatory response, and it's safe and reliable. [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Tianjin Medical Journal is the property of Tianjin Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)