1. 卵母细胞透明带异常及其对助孕结局影响的研究进展.
- Author
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段超群, 滕璨, 张硕屏, 卢光琇, and 林戈
- Abstract
The human zona pellucida (ZP) is a highly organized structure that is formed during folliculogenesis, and consists of four glycoproteins (ZP1-ZP4) which are secreted by oocytes and granulosa cells. The human ZP is a very vital structure related to oocyte maturation, normal fertilization, embryo development and pregnancy outcome. Many laboratories of assisted reproductive centers found that the oocytes of few patients exhibited abnormal zona pellucida, and the types of abnormal zona pellucida varied from laboratory to laboratory. Many studies found that these abnormal zona pellucida morphologies had a certain correlation with oocyte fertilization, embryo development and the clinical outcome.In this paper, the studies about the zona pellucida and their influence on the fertilization, embryo development potential and the pregnancy outcome were reviewed. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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