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回顾性分析1例在首都医科大学附属北京潞河医院内分泌科住院的2型糖尿病合并肥 胖患者，由多种口服降糖药物转换为司美格鲁肽降糖治疗的过程并进行文献复习。患者为54岁中年 男性，糖尿病病程15年，院外应用格列美脲、阿卡波糖、二甲双胍3种口服药物治疗，血糖控制不佳，糖 化血红蛋白 12.2%，空腹血糖 13.65 mmol/L，入院后逐步调整治疗方案为卡格列净（100 mg，1 次/d）联 合司美格鲁肽（0.5 mg，1次/周）皮下注射治疗，患者血糖控制良好，体重由 90 kg下降至 62 kg，未出现 低血糖。 [ABSTRACT FROM AUTHOR]

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