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Copyright of Journal of China University of Petroleum is the property of China University of Petroleum and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nankai Business Review is the property of Nankai Business Review Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This article reviews the changes in London's industrial space since the 17th century and its interaction with space development strategy, identifies the driving forces that promote the continuous transformation and upgrading of the London city, and interprets London's industrial space-land use interaction experience of growing into a global city. The research finds that: ① The driving force for London's urban transformation stems in the combined effect of market and policy intervention, the result of the gradual adjustment of the urban land use structure and the continuous upgrading of the industrial structure. ② Before 1940, the market driving force was strong, and London spontaneously formed a spatial layout of gradually decreasing population density and industrial level from the city center to the periphery; after 1940, the role of policy became prominent. ③ Since 1940, London's urban industrial space has undergone three significant changes with urban policies: In 1940, London implemented a decentralization strategy, and the green belt restricted land development in the inner city, which caused the migration of population industries and the hollowing of the city; Since the 1980s, it has shifted to the development strategy of compact city, emphasizing the efficient use of inner city land, and the revival of inner city economic space; when in the 21st century, sustainable development strategy has become the main theme, strengthening the functions of the central business district, ensuring the advantages of financial services, and driving the sustained growth of London's economy. The improvement in the quality of production and life has consolidated London's status as a global financial center. [ABSTRACT FROM AUTHOR]

With society’s progression, the rapid advancements in science and technology, and the continual economic growth, a heightened emphasis on health and sports is observed. Sports footwear plays an indispensable role in various sporting activities, and, with the progress in science and technology, these products are continually evolving to cater to diverse requirements. Nevertheless, this evolution has led to the manufacturing and disposal of substantial quantities of sports footwear, thereby adversely impacting the environment. Our Common Future advocates for sustainable development that fulfills the present generation’s needs without jeopardizing those of the future generations. In the contemporary context, global concerns regarding sustainability have made it imperative to tackle the environmental pollution stemming from sports footwear across its life cycle. The research focuses on sports footwear and employs a modular design approach to investigate sustainable solutions for sports shoes from a sustainability perspective.In this examination of existing sustainable and modular shoes, the article aimed to elucidate their strengths and limitations concerning sustainability. Sustainable footwear of the present excels in various aspects, including the utilization of recycled materials, reduction of environmental impact, increased adaptability, and the consideration of social equity concerns. Nevertheless, the use of adhesives in assembly processes impedes recycling efforts and inflates disposal costs. In the meanwhile, modular sports footwear often lacks sustainability considerations. To address these sustainability challenges, the study embraced a comprehensive approach that places significant emphasis on full life-cycle sustainability, modular design, and the enhancement of recovery and recycling processes. The article approached the formulation of a sustainable design strategy for modular footwear from a systematic perspective. It outlined a threefold approach to constructing a sustainable modular sports footwear system. Firstly, it is necessary to create a modular system with detachable structures, tailored to user needs and sustainability. Employing the system-function-structure layering model, the article analyzed the structure and function of sports shoes to provide the foundation for module segmentation, and establish a connection with user needs. The article gathered user needs through desktop research, questionnaires, and interviews, providing the basis for module segmentation and subsequent design. In terms of structure, each module was designed without the use of adhesive, facilitating individual disassembly, thereby enhancing production efficiency and recycling ease. Secondly, material selection guided shall be by life cycle and recycling design principles, and it is necessary to prioritize natural materials with minimal environmental impact and recyclable materials. Thirdly, it is necessary to enhance the end-to-end service system design and business chain to improve the user experience throughout the entire process. From a product and service system design perspective, the article created a systematic process that spans from purchase to recycling and replacement. Finally, from the four design elements of structural division, user demand, material selection and system service, the specific design practice was verified. It is found that by applying the proposed design strategy to the specific sports footwear design, the improved solution exhibits enhanced sustainability, with an improved overall evaluation of the design’s ability to better meet user needs while striving for sustainability. Considering that it offers improved repairability but relatively weak durability, subsequent solutions can focus on further optimizing and strengthening the durability to meet evolving user demands.The modular design approach offers a novel avenue for sustainable footwear design, addressing key innovation challenges in the field. It effectively reduces the consumption of non-renewable resources, and mitigates environmental pollution by employing natural and biodegradable materials. The modular structure facilitates easy assembly and recycling, enhances production efficiency, and allows for personalized customization. Compared to traditional sports shoes, sustainable modular sports footwear caters to individual preferences while emphasizing environmental friendliness and recyclability. It preserves the performance characteristics of sports footwear and provides valuable insights for the sustainable design of sports shoes. [ABSTRACT FROM AUTHOR]

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Xi'an Jiaotong University (Social Sciences) is the property of Journal of Xi'an Jiaotong University (Social Sciences) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rolling Stock (1002-7602) is the property of Rolling Stock Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Prataculturae Sinica is the property of Acta Prataculturae Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Soil salinization has been one of the major soil degradation processes threatening the natural ecosystem in the world. Effective utilization of water resources can be used to prevent soil salinization so far. It is of great significance to clarify the spatial distribution characteristics of soil salt leaching quota in the fallow period in the arid region of Northwest China. However, the point-scale salinity leaching quota cannot fully reflect the regional situation, due mainly to the spatial variability of soil salinity and texture. Taking the Alar irrigation district of southern Xinjiang as an example, this study aims to obtain the spatial distribution characteristics of soil salinity and texture using remote sensing images in recent 20 years. Spatial interpolation was also combined to extract the land use data. The hydraulic response unit was then identified with the identical simulation condition using Simultaneous Heat and Water (SHAW) model. An improved distributed model was established to clarify the spatial distribution characteristics of appropriate salt leaching quota under different irrigation modes. The results showed that there was ever-increasing farm land over the past 20 years, in terms of the main land use type and the area in the north of the irrigated areas. An outstanding spatial variability was also found in the soil salinity areas. Specifically, the randomness and variability of the surface layer were higher than those of the deep layer in this case. The soil was mostly at the level of mild salinization in the irrigated areas. In the distribution of soil salt, the soil salt content was larger in the west than in the east, while larger in the south than in the north. The farm land in the north of the irrigation area was mostly formed by the late reclamation of wasteland, indicating the higher content of soil base salt. Meanwhile, the soil salinity was significantly higher than that in the south. Furthermore, the soil texture presented the silt and sandy loam, accounting for about 36.81% and 19.44% of the soil, respectively. As such, the soil salinity and sand content were the main influencing factors on the salt leaching quota. An optimal salt leaching was carried out to fully meet the soil moisture content suitable for the cotton emergence in the next spring. Nevertheless, the high sand content normally led to low soil water retention. Particularly, the smaller quota of winter irrigation cannot provide the soil moisture content that is required by crops in spring. At the same time, only winter irrigation treatment was very necessary to leach the salt into the deeper soil layer using the higher irrigation quota, in order to reduce the soil salt returning. By contrast, only spring irrigation treatment was considered whether the soil condition after irrigation met the hydrothermal and salt conditions required for the cotton seedling emergence. The salt leaching quota of only winter irrigation was generally higher than that of only spring irrigation and winter irrigation + a small amount of spring irrigation. Only spring irrigation treatment was required for the minimum salt leaching quota. But, the salt accumulation resulted in the soil during the growth period during only spring irrigation treatment, due to the limitation of salt leaching depth. The treatment of winter irrigation + a small amount of spring irrigation (300 m3/hm2) was combined with the advantages of the rest of the three irrigation modes (only winter irrigation, only spring irrigation, and winter irrigation + a small amount of spring irrigation). The suitable winter irrigation quota of winter irrigation + a small amount of spring irrigation in the irrigated area was mainly between 1 500 and 2 250 m3/hm2, indicating the most beneficial option for water saving and crop emergence. This finding can also provide a strong reference for the optimal allocation of local water resources in the control of soil salinization. [ABSTRACT FROM AUTHOR]

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Coal Science & Technology (0253-2336) is the property of Coal Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agriculturae Zhejiangensis is the property of Acta Agriculturae Zhejiangensis Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the association of the clinical features of liver cancer patients, including albumin-bilirubin( ALBI)and neutrophil-lymphocyte ratio( NLR), with the traditional Chinese medicine( TCM) syndrome types of primary liver cancer, and to establish a clinical judgment model for TCM syndrome differentiation of primary liver cancer. Methods A total of 289 previously untreated patients who were admitted to The Affiliated Tumor Hospital of Guangxi Medical University from November 1, 2016 to October 31, 2018 and were diagnosed with primary liver cancer based on pathology or clinical examination were enrolled, and TCM syndrome differentiation was performed for all patients. A one-way analysis of variance was used for comparison of normally distributed continuous data between groups, and the Kruskal-Wallis H test was used for comparison of non-normally distributed continuous data between groups; the chi-square test was used for comparison of categorical data between groups. The data with significant difference in the univariate analysis were included in the logistic regression analysis, and the receiver operating characteristic( ROC) curve was used to evaluate the efficiency of these clinical features in the TCM syndrome differentiation of liver cancer. Results There were significant differences between the patients with different TCM syndrome types of liver cancer in ALBI( F = 5. 487, P < 0. 001), NLR( χ2= 30. 146, P < 0. 001), BCLC stage( χ2= 71. 973, P <0. 001), albumin( Alb)( χ2= 18. 887, P < 0. 001), total bilirubin( TBil)( χ2= 12. 138, P = 0. 007), alanine aminotransferase( ALT)( χ2= 18. 001, P < 0. 001), aspartate aminotransferase( χ2= 12. 067, P = 0. 007), absolute neutrophil count( F = 6. 262, P < 0. 001), absolute lymphocyte count( F = 2. 934, P = 0. 034), diameter of intrahepatic primary tumor( F = 4. 905, P = 0. 002), ascites( χ2=9. 034, P = 0. 021), portal vein tumor thrombus( χ2= 13. 434, P = 0. 004), and number of extrahepatic metastatic lesions( χ2= 2. 529, P= 0. 002). The logistic regression analysis showed that ALT( odds ratio [OR]= 1. 002, 95% confidence interval [CI]: 1. 003-1. 021, P< 0. 05) and BCLC stage( OR = 0. 591, 95% CI: 0. 413-0. 845, P < 0. 05) were independent factors for judging damp-heat accumulation; ALT( OR = 0. 985, 95% CI: 0. 974-0. 997, P < 0. 05) and BCLC stage( OR = 3. 191, 95% CI: 2. 042-4. 986, P < 0. 05) were also independent factors for judging liver depression and spleen deficiency; TBil( OR = 0. 966, 95% CI: 0. 937-0. 995, P < 0. 05), Alb( OR = 1. 259, 95% CI: 1. 064-1. 490, P < 0. 05), and ALBI( OR = 0. 088, 95% CI: 0. 013-0. 607, P < 0. 05) were independent factors for judging Qi stagnation and blood stasis. The ROC curve analysis showed that ALT and BCLC stage had an area under the ROC curve( AUC) of 0. 662( 95% CI: 0. 605-0. 717), a sensitivity of 69. 4%, and a specificity of 58% in judging damp-heat accumulation, at the cut-off values of 36 U/L for ALT and stage C for BCLC stage; ALT and BCLC stage had an AUC of 0. 753( 95% CI: 0. 699-0. 801), a sensitivity of 72. 7%, and a specificity of 68. 2% in judging liver depression and spleen deficiency, at the cut-off values of 64 U/L for ALT and stage B for BCLC stage; TBil, Alb, and ALBI had an AUC of 0. 634( 95% CI: 0. 576-0. 690), a sensitivity of 56. 7%, and a specificity of 65. 3% in judging Qi stagnation and blood stasis, at the cut-off values of 28. 4 μmol/L for TBil, 37. 8 g/L for Alb, and 1. 95 for ALBI. Conclusion The clinical judgment model based on ALT, BCLC stage, TBil, Alb, and ALBI can differentiate between the TCM syndrome types of damp-heat accumulation, liver depression and spleen deficiency, and Qi stagnation and blood stasis for liver cancer, and this model is simple, convenient, and objective and thus holds promise for clinical application. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Prataculturae Sinica is the property of Acta Prataculturae Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Harbin Institute of Technology. Social Sciences Edition / Haerbin Gongye Daxue Xuebao. Shehui Kexue Ban is the property of Harbin Institute of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

ObjectiveTo investigate the risk factors for variceal rebleeding after esophagogastric devascularization and splenectomy in patients with portal hypertension. MethodsA retrospective analysis was performed for the clinical data of 244 patients with portal hypertension who were admitted to Beijing YouAn Hospital from April 2010 to September 2015 and underwent esophagogastric devascularization and splenectomy. According to the presence or absence of variceal rebleeding, these patients were divided into non-rebleeding group and rebleeding group. Preoperative, intraoperative, and postoperative clinical data were compared between the two groups. The t-test was used for comparison of normally distributed continuous data between groups, and the Wilcoxon rank-sum test was used for comparison of non-normally distributed data between groups; the chi-square test was used for comparison of categorical data between groups. A multivariate logistic regression analysis was performed for statistically significant variables identified by the univariate analysis. ResultsOf all 244 patients, 38 (15.6%) experienced variceal rebleeding. The univariate analysis showed that there were significant differences between the two groups in the history of variceal bleeding, preoperative ascites, total bilirubin after surgery, portal venous pressure after devascularization, portal venous pressure before and after splenectomy, and preoperative international normalized ratio (χ2=5.530、4.120，t=3.591、4.098、2.516、2.622、4.278，P=0.016, 0.026, 0.008, 0.002, 0.022, 0.012, and 0.003). The multivariate logistic regression analysis showed that variceal rebleeding after esophagogastric devascularization and splenectomy was associated with the history of variceal bleeding (95%CI:1.113-13.704，P=0.033), preoperative ascites (95%CI:1.257-5.437,P=0.010), and portal venous pressure after devascularization (95%CI:1.022-1.172,P=0.010). ConclusionHistory of variceal bleeding, preoperative ascites, and portal venous pressure after devascularization are independent risk factors for variceal rebleeding after esophagogastric devascularization and splenectomy. [ABSTRACT FROM AUTHOR]

In order to overcome the drawbacks of using either spectral or morphological features for traditional image segmentation methods, a multi-scale image segmentation method using both the spectral and morphological information is proposed. First of all, Differential Morphological Profiles are combined with spectral features to form spectral-morphological characteristics. Then, Hausdorff distance is implemented to calculate the weight of edges based on graph theory and minimum spanning tree algorithm Kruskal is applied to complete the initial segmentation of color images. Finally, the obtained segmentation result is refined by a region merging procedure with the regional heterogeneous criteria proposed in fractal network evolution. Furthermore, object-based Gray Level Co-occurrence Matrix and object-based Pixel Shape Index are proposed on the basis of segmentation results. Experimental results show that the proposed segmentation method is more effective and more efficient than eCognition software 8.0 and Meanshift algorithm. In addition, object-based Gray Level Co-occurrence Matrix and object-based Pixel Shape Index are apparently better than traditional pixel-based methods. [ABSTRACT FROM AUTHOR]

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To compare the effect of the penetrating-suture pancreaticojejimostomy and traditional sumre in pancreaticoduodenectomy(PD), and analyze their application value in PD. Methods: The data of 60 patients underwent PD in our hospital from September 2010 to December 2015 were collected, who were divided into two groups according to the difference of the anastomosis Methods: The penetration group and traditional group, with 30 patients in each group. The penetration group was treated with penetrating-suture pancreaticojejimostomy, while the traditional group was treated with traditional suture. Compared the clinical indexes (time of pancreaticojejimostomy, amount of bleeding during operation and postoperative hospital stay) and perioperative complications (such as pancreatic fistula, lymph leakage, gastric emptying, pulmonary infection, anastomotic bleeding, abdominal abscess, etc). Then compared the rates of re-operation, re-admission between the two groups. Results: The time of pancreaticojejimostomy, amount of bleeding dining operation and postoperative hospital stay in penetration group were lower than the traditional group, the differences were statistically significant (P<0.05). The incidence of perioperative pancreatic fistula was 10.00% in penetratnion group, which was significantly lower than 40.00% in the traditional group, the difference was statistically significant(P<0. 05), and the B grade pancreatic fistula hi penetratnion group was significantly lower than traditional group, the difference was statistically significant (P<0.05). There was no significant difference in the rates of re-operation, re-admission between the two groups (P>0.05). Conclusion: Penetrating-suture pancreaticojejimostomy is good for postoperative recovery of patients with PD. and the incidence of perioperative pancreatic fistula is low, which is a effective mothod of intestinal anastomosis. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Along with the great improvement of the image spatial resolution of the geostationary satellite, elevation correction of geostationary satellite is increasingly attractive. According to the projective mode and imaging pattern of new generation geostationary satellites, in order to address the non-convergent problem caused by traditional iterative searching algorithm, a new algorithm which searches the occlusive points directly on the observing vectors is proposed. Then, a geostationary satellite elevation correction strategy which combines the strong stability of direct searching algorithm and high computational efficiency of iterative searching algorithm is developed. The simulative experiments show that the proposed strategy is valid. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to investigate the bond-slip behavior between steel bars and recycled concrete, the bond-slip properties of 13 reinforced medium/high strength recycled concrete beam-type specimens were tested. The effects of the shape of steel bar, the length of anchorage, the strength of concrete and the replacement ratio of recycled aggregate on the bond-slip behavior between steel bars and recycled concrete were studied. Research shows that ： when the recycled coarse aggregate replacement is 33% - 6 6% and the fine aggregate is natural sand, the bond strength between steel bar and recycled concrete is basically coincident with ordinary concrete. When the replacement rate of recycled coarse aggregate is 100% and the fine aggregate is over 50%，the bond behavior between rebars and recycled concrete is degraded distinctly. Compared with the ordinary concrete specimens，the bond efficiency coefficient of the relative concrete strength of the recycled coarse aggregate concrete specimens is higher. The bond strength between deformed bars and recycled concrete is better than plain ones. The bond strength between steel and recycled concrete decreases with the increase of the anchorage length of reinforcement. The calculated values of the fitted bond-slip constitutive model agree with the experimental values well. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Taiwanese Journal of Agricultural Chemistry & Food Science is the property of Agricultural Chemical Society of Taiwan and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To evaluate the safety of programmed cell death protein 1 (PD-1) inhibitor in the treatment of primary liver cancer (liver cancer) before liver transplantation. Methods Clinical data of 7 recipients given with PD-1 inhibitor before liver transplantation for liver cancer were retrospectively analyzed. The incidence of immune-related adverse event (irAE) and clinical prognosis of the recipients were summarized. The safety of PD-1 inhibitor in recipients prior to liver transplantation for liver cancer was evaluated. Results Seven recipients were treated with PD-1 inhibitor with 1-20 courses before liver transplantation for liver cancer. The time interval from drug withdrawal to liver transplantation was 6-120 d. Five recipients suffered from irAE of different degrees, including fatigue in 3 cases, fever in 2 cases, alopecia in 2 cases, rash in 1 case, nausea in 1 case and myocarditis in 1 case, respectively. A majority of these irAE were classified as grade - . One recipient died from grade irAE (fatal myocarditis). One recipient developed rejection at postoperative 7 d, which were mitigated after glucocorticoid pulse therapy combined with increased dosage of tacrolimus. Conclusions PD-1 inhibitor can be applied in preoperative treatment before liver transplantation for liver cancer. Nevertheless, the incidence of irAE and postoperative rejection should be intimately monitored. [ABSTRACT FROM AUTHOR]

Objective To evaluate the safety and efficacy based on cytochrome P450(CYP)3A5*1 gene polymorphisms in guiding the individualized medication of tacrolimus (FK506) after liver transplantation. Methods Clinical data of 100 consecutively enrolled recipients who underwent liver transplantation for the first time were analyzed and randomly divided into experimental group and control group, with 50 cases in each group. The donors and recipients in the experimental group received preoperative CYP3A5 gene detection, and determined the FK506 medication regimen according to the CYP3A5*1 genotype. The compliance rate of FK506 target blood concentration, the recovery rate of liver function in the two groups of recipients at 7, 14, 28 d and 3, 6, 9, 12 months postoperatively, as well as the number of FK506 dosage adjustment during the follow-up were observed. The 1-year graft survival rate and the incidence of complications were recorded in both groups of recipients, such as acute rejection, infection, acute kidney injury, gastrointestinal symptoms, de novo hypertension, de novo diabetes, colds and rash, etc. Results The differences of the compliance rate of FK506 target blood concentration between the two groups of recipients at 7, 14 d after operation were statistically significant (both P<0.05). There was no statistically significant difference between the two groups in the compliance rate of FK506 target blood concentration at 28 d and 3, 6, 9, 12 months and the recovery rate of liver function at the 7 observation time points after operation (all P>0.05). The difference between the two groups of recipients in number of FK506 dose adjustment during follow-up was statistically significant (P=0.021). There were no statistically significant differences in 1-year graft survival rate and incidence of complications between the two groups of recipients after operation and during follow-up (all P>0.05). Conclusions It is safe to guide individualized medication of FK506 after liver transplantation according to CYP3A5*1 gene polymorphism. It can increase the compliance rate of FK506 target blood concentration of recipients in the early postoperative stage, and can effectively reduce the number of dose adjustment during follow-up. [ABSTRACT FROM AUTHOR]

Objective To explore the safety application of organs from infectious donors. Methods Clinical data of 67 donors and recipients undergoing orthotopic liver transplantation were retrospectively analyzed. According to the occurrence of infections and infection sites in donors, all recipients were divided into the bloodstream infection group (n=16, donors with non-drag resistant bacterial infections), non-bloodstream infection group («=20, donors with other site infections) and non-infection group («=31). Perioperative clinical parameters including preoperative model for end-stage liver disease (MELD) score, operative time, anhepatic phase, intraoperative blood loss and intraoperative blood transfusion were statistically compared among three groups. The recovery of liver function and coagulation function in the recipients was observed at postoperative 1, 3, 7,14 and 21 d. The incidence rate of complications and mortality rate in the recipients were recorded within 1 month after liver transplantation. The recovery of postoperative infection-related parameters including white blood cell (WBC), neutrophil pet (NE%) and procalcitonin (PCT) level in the recipients was observed. The application rate and application time of restricted antibiotics were recorded. Results Perioperative clinical parameters in the recipients did not significantly differ among three groups (all P>0.05). At each time point after liver transplantation, the liver function, coagulation function, incidence rate of complications and mortality rate in the recipients did not significantly differ among three groups (all P>0.05). The NE% of recipients at postoperative 3 and 7 d in the bloodstream infection group was significantly higher than those in non-bloodstream infection and non-infection groups (all P<0.05). The PCT levels of recipients at postoperative 3, 7 and 14 d in the bloodstream infection group were significantly higher than those in the non-bloodstream infection and non-infection groups (all P<0.05). The application rate and application time of restricted antibiotics in the recipients with bloodstream infections were significantly higher or longer than their counterparts in the non-bloodstxeam infection and non-infection groups (all P<0.05). Conclusions It is safe to apply liver grafts from donors with bloodstream infection of non-drug resistant bacteria or other site infections when antibiotics are applied as early as possible. [ABSTRACT FROM AUTHOR]

Hepatic artery reconstruction is one of the key procedures in liver transplantation. Accidental dissection of the hepatic artery to be reconstructed caused by donor and recipient factors or surgical factors will disrupt the surgical plan, increase the difficulty of arterial reconstruction, significantly prolong the operation time, increase the risk of postoperative arterial stenosis and thrombosis and probably lead to acute allograft failure, which requires emergency surgical interventions or even secondary liver transplantation. Understanding of how to avoid dissection of the artery to be anastomosed during liver transplantation and corresponding treatment will contribute to preventing the incidence of arteryrelated complications during liver transplantation and improving clinical prognosis of liver transplant recipients. In this article, the causes, prevention and treatment of hepatic artery dissection and hepatic artery reconstruction in donors and recipients during liver transplantation were illustrated. [ABSTRACT FROM AUTHOR]

To investigate the deformation performance of high strength recycled reinforced concrete beams under long-term loading, the long-term deflection tests of six recycled reinforced concrete beams were carried out. The beam cross section was 200mm×300mm, and the length was 3300mm and the span was 3000mm. The reinforcement details of specimens were the same. The longitudinal reinforcement ratio was 1.13% and the stirrup volumetric ratio was 0.54%. The concrete cover depth of longitudinal reinforcement was 20mm. The strength level of recycled concrete was C55~C60. The concrete was recycled coarse aggregate (RCA) concrete, and the fine aggregate was natural sand. The replacement ratio of RCA included 0%, 33%, 66%, 100%, and there were two loading levels. The test has already continued under long-term loading, and the load value, deflection, temperature and humidity have been recorded. The developing rule of beams’ deflection of different loading levels and different replacement ratios of RCA were analyzed. The formula between deflection and time was obtained by fitting curves. Results show that: the creep deflection of high strength recycled reinforced concrete beams is slightly larger than the creep deflection of natural aggregate concrete beams under low loading level (The ratio of loading moment to yield moment is 0.29). The deflection increasing coefficient under low loading level is slightly higher than that under high loading level (The ratio of loading moment to yield moment is 0.46 and 0.47). The deflection increasing coefficient of recycled concrete beams could adopt 1.1 times of the deflection increasing coefficient of normal concrete beam. The calculated values of deflection obtained by curve fitting and piecewise linear fitting are in good agreement with the measured values. [ABSTRACT FROM AUTHOR]