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Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Anhui Agricultural Sciences is the property of Journal of Anhui Agricultural Sciences Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agronomica Sinica is the property of Crop Science Society of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Bulletin of the Chinese Ceramic Society is the property of Bulletin of the Chinese Ceramic Society Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Digital Education is the property of Haiyan Publishing Co. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food & Machinery is the property of Food & Machinery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of China Pulp & Paper is the property of China Pulp & Paper Magazines Publisher and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Oil Drilling & Production Technology / Shiyou Zuancai Gongyi is the property of Shiyou Zuancai Gongyi Bianjibu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

胰岛β细胞功能障碍是糖尿病发生发展的关键病理生理机制之一。机体代谢稳态失衡 的共同作用最终会导致β细胞功能障碍。胰腺、肝脏、肠道等多个重要器官（组织）可通过与胰岛对 话, 从而调控β细胞功能。深入理解上述调控作用及其机制, 将有助于进一步阐明糖尿病的发病机 制, 促进糖尿病治疗新策略的研发。. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Diabetes Mellitus is the property of Chinese Journal of Diabetes Mellitus and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Anhui Agricultural Sciences is the property of Journal of Anhui Agricultural Sciences Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Neurosurgery / Linchuang Shenjingwaike Zazhi is the property of Editorial Board of Journal of Clinical Neurosurgery and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Advances in Earth Science (1001-8166) is the property of Advances in Earth Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To compare the safety and efficacy of alfentanil and sufentanil in painless gastrointestinal endoscopy. Methods A total of 326 patients who underwent painless gastroenteroscopy from March to September 2021 were selected and divided into the afentanil group (group A,163 cases) and the sufentanil group (group S,163 cases) by random number table method. Before surgery, the group A was intravenously injected with afentanil 5 μg/kg, and the group S was intravenously injected with sufentanil 0. 1 μg/kg, and 1 minute later, propofol 2 mg/kg was slowly injected. The modified observer′s assessment of alert (MOAA/S) was assessed immediately until MOAA/S≤1,and the procedure was initiated. If there was movement during the process, add propofol 0. 5 mg/kg. Anesthesia onset time, recovery time, operation time and the amount of propofol were recorded. Calculating the cost of narcotic drugs for patients; The patients′ satisfaction with the depth of anesthesia, the smooth placement of endoscope and whether there was resistance were recorded to evaluate the anesthetic effect. Pain score after awakening, blood pressure (BP), heart rate (HR), respiratory rate (RR), and percutaneous oxygen saturation (SpO2) were recorded before anesthesia (T0), at the start of surgery (T1), and at exit (T2) . Abnormal signs and indicators were recorded during surgery, and the occurrence of other adverse reactions within 24 h after the completion of surgery. Results The dosage of propofol in the group A[ (143. 10±31. 91) mg] was significantly less than that in the group S[ (168. 19±50. 95) mg],and the cost of narcotic drugs in the group A[ (94. 04±1. 46) yuan] was significantly higher than that in the group S[ (69. 79±6. 01) yuan],with statistical significance (P＜0. 05) . The onset time of anesthesia, recovery time and operation time of the group A[ (1. 28±0. 59), (9. 93±3. 82), (15. 65±7. 57) min] were shorter than those of the group S[ (1. 64±1. 12), (11. 29±4. 02), (19. 68±9. 23) min]. The differences were statistically significant (P＜0. 05) . There was no significant difference in patient and physician satisfaction between the two groups (P＞0. 05) . BP,HR,RR and SpO2 of patients in the group A and group S at T1 and T2 were changed to different degrees, but there was no significant difference in the proportion causing adverse effects on cardiovascular and respiratory system or requiring clinical intervention (P＞0. 05) . There was no statistical significance in the incidence of all kinds of adverse reactions between the two groups within 24 h (P＞0. 05) . Conclusion Alfentanil and sufentanil combined with propofol can be safely and effectively used in painless gastroenteroscopy. The afentanil 5 μg/kg combined with propofol anesthesia is rapid, stable, rapid recovery, and similar to sufentanil in safety, which has obvious advantages in short surgical anesthesia such as examination operation. [ABSTRACT FROM AUTHOR]

近年来细胞死亡方式在前列腺癌中研究的越来越多, 包括凋亡, 自噬和铁死亡. 前列腺癌是男性常见的恶性肿瘤之 一, 细胞死亡在前列腺癌发生发展中起到关键作用, 大部分研究者拟通过抑制前列腺癌细胞增殖并促进细胞死亡寻找新的治 疗方法. 大量研究表明, 铁死亡在前列腺癌发生发展, 肿瘤诊断, 治疗和预后具有极大的研究价值. 本文就铁死亡在前列腺 癌中的机制和治疗前景最新研究进行综述. [ABSTRACT FROM AUTHOR]

Copyright of Oil Drilling & Production Technology / Shiyou Zuancai Gongyi is the property of Shiyou Zuancai Gongyi Bianjibu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Anhui Agricultural Sciences is the property of Journal of Anhui Agricultural Sciences Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the effects of pristimerin on the proliferation and apoptosis of human bladder cancer HT ⁃ 1376 cells and the related mechanisms. Methods The target protein of pristimerin was predicted by TCMSP, SwissTargetPrediction data⁃ base and PharmMapper database, and the target of bladder cancer was obtained from GeneCards database. The potential targets of pris⁃ timerin in the treatment of bladder cancer were integrated through the Venny 2.1.0 platform; the String database and Cytoscape 3.9.1 software were used to construct a protein⁃protein interaction (PPI) network. GO function and KEGG pathway enrichment analyses were performed by DAVID database. The normal human bladder epithelial cells SV⁃HUC⁃1 and human bladder cancer cell line HT⁃1376 cells were cultured in vitro, and treated with 0-0.8 μmol/L pristimerin. The effects of pristimerin on the proliferation and apoptosis of HT⁃1376 cells were detected by CCK ⁃8 assay, colony formation assay, Hoechst⁃PI staining assay. Western blot was used to detect the expression levels of apoptosis⁃related proteins Bcl⁃2, Bax, Cleaved PARP, PARP, and MEK/ERK signaling pathway⁃related proteins p⁃MEK, p⁃ERK1/2. Results There were 292 targets of pristimerin, among which 114 potential targets were related to bladder cancer treatment, involving 434 biological processes, 54 cellular components and 114 molecular functions, mainly enriched in 132 signaling pathways such as MAPK signaling pathway, lipid and atherosclerosis, etc. The results of in vitro experimental verification showed that pristimerin could significantly inhibit the viability and colony formation ability of HT ⁃ 1376 cells and induce cell apoptosis(all P<0.05). Western blot showed that compared with untreated control group, the expression levels of apoptosis⁃related proteins Bax and Cleaved PARP were in⁃ creased, Bcl⁃2 and PARP were decreased, and MEK/ERK signaling pathway⁃related proteins p⁃MEK and p⁃ERK1/2 were decreased after treated with 0.65 μmol/L pristimerin (all P<0.05). Conclusions Pristimerin may inhibit the proliferation and induce apoptosis of bladder cancer cells by regulating the phosphorylation level of MEK/ERK signaling pathway⁃related proteins. [ABSTRACT FROM AUTHOR]

Copyright of Oil Drilling & Production Technology / Shiyou Zuancai Gongyi is the property of Shiyou Zuancai Gongyi Bianjibu and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of South China Normal University (Natural Science Edition) / Huanan Shifan Daxue Xuebao (Ziran Kexue Ban) is the property of Journal of South China Normal University (Natural Science Edition) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Water Conservancy & Electric Power Technology & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of China University of Petroleum is the property of China University of Petroleum and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Asian Journals of Ecotoxicology is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Multipurpose Utilization of Mineral Resources / Kuangchan Zonghe Liyong is the property of Multipurpose Utilization of Mineral Resources Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Rock & Mineral Analysis is the property of Editorial Board of Rock & Mineral Analysis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Applied Entomology is the property of Chinese Journal of Applied Entomology, Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: For complex knee osteoarthritis, traditional surgical instruments for osteotomy positioning technology can easily lead to poor placement of artificial total knee arthroplasty prostheses. Personalized three-dimensional printed osteotomy guide plate can achieve accurate osteotomy and prosthesis placement. OBJECTIVE: To investigate the early clinical effects of total knee arthroplasty with personalized three-dimensional printed osteotomy guide plates in the treatment of advanced knee osteoarthritis with femoral deformities. METHODS: Thirty-one patients with severe knee osteoarthritis combined with femoral deformity admitted to the Fifth Affiliated Hospital of Guangzhou Medical University from June 2016 to May 2020 were enrolled in the study. There were 14 males and 17 females, which aged 54-88 years old. A personalized three-dimensional printed osteotomy guide plate was used to assist in total knee arthroplasty surgery. Imaging measurement was conducted before treatment and at 3 days after treatment, to measure the included angle between femur and tibia mechanical axis, posterior condylar angle, patella transverse axis-femoral transepicondylar axis angle. American Hospital of Special Surgery score, Visual Analogue Scale score and range of motion of the knee joint were measured and assessed before and at 6 and 12 months after treatment. RESULTS AND CONCLUSION: All the 31 patients were followed up for more than 12 months, and no adverse advents related to implant materials occurred during the trial and follow-up. At 3 days after treatment, the included angles between the femur and tibia mechanical axis, posterior condylar angle, and patella transverse axis-femoral transepicondylar axis angles were lower than those before treatment in all the patients (all P=0.000). At 6 and 12 months after treatment, the American Hospital of Special Surgery score and the range of motion of the knee were higher than those before treatment in all the patients (P < 0.05), while the Visual Analogue Scale scores were lower than those before treatment (P < 0.05). Therefore, total knee arthroplasty with the assistance of three-dimensional printed personalized osteotomy guide plates can relieve joint pain, improve joint function, restore lower limb force lines and femoral rotation alignment, and improve patellar trajectory in patients with advanced knee osteoarthritis combined with femoral deformities. [ABSTRACT FROM AUTHOR]

Copyright of Cotton Textile Technology is the property of Cotton Textile Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food & Machinery is the property of Food & Machinery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

我国成人糖尿病前期（preDM）患病率仍在持续攀升, 目前preDM干预和管理面临诸多 困难和挑战。该文对preDM研究领域的国内外进展进行评述, 并着重对我国社区preDM管理模式和 综合管理体系建设进行讨论。. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Diabetes Mellitus is the property of Chinese Journal of Diabetes Mellitus and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)