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天津妊娠期糖尿病预防项目始于1998年, 监测了市内6区的妊娠期糖尿病（GDM）的患 病率, 探索了GDM的危险因素, 研发了GDM预测模型。该项目发现, 孕15周内生活方式干预可降低 20%的GDM风险;强化生活方式干预GDM可改善妊娠结局, 降低巨大儿发生率;GDM增加母亲产后 糖尿病风险, 其峰值在产后3~6年和40岁之前;妊娠期干预GDM对母亲产后糖尿病无效, 但产后3年 内生活方式干预可降低糖尿病危险因素及43%的糖尿病风险;GDM后代儿童期肥胖增高, 但孕期干 预GDM对后代婴幼儿期及儿童期肥胖无效。我们呼吁建立连续的, 贯穿于孕前、孕中及产后的GDM 综合防控策略。. [ABSTRACT FROM AUTHOR]

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