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Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the clinical efficacy and mechanism of action of retention enema Qing Yi Decoction combined with ERCP in the treatment of acute cholinergic pancreatitis. Methods: 97 cases of patients with acute cholinergic pancreatitis from Jan. 2015 to Dec. 2017 in our hospital were selected and divided into the control group (ERCP, 46 cases) and the observation group (retention enema Qing Yi Decoction combined with ERCP, 53 cases) according to different treatment methods. The clinical efficacy of TCM between the two groups were observed and compared. The levels of serum TNF-α, CRP, IL-6, IL-8, IL-10, amylase, abdominal pain relief time, average hospitalization time and average hospitalization cost were observed and compared before and at 12 h, 24 h, 7 days after treatment. Results: After treatment, the cure rate and markedly effective ratio of observation group were significantly higher than those of the control group (P<0.05). The levels of serum TNF-α, CRP, IL-6, IL-8 and IL-10 in the two groups were significantly lower than those before treatment, and the levels of serum TNF-α, CRP, IL-6 and IL-8 in the observation group were significantly lower than those in the control group (P<0.05); there was no significant difference in the average hospitalization expense between the two groups (P>0.05); the abdominal pain relief time and the average hospitalization time in the observation group were significantly lower than those in the control group (P<0.05). Compared with those before treatment, the serumamylase levels of both groups at 12 h, 24 h and 3 d after treatment were significantly decreased, and the serum amylase levels of observation group at 12 h and 24 h after treatment were significantly lower than those of the control group (P<0.05). Conclusion: Retention enema Qing Yi Decoction combined with ERCP treatment could significantly improve the heal and efficacy rate of acute cholinergic pancreatitis, and its mechanism may be related to the reduction of serum TNF-α, CRP, IL-6, IL-8 and amylase levels. [ABSTRACT FROM AUTHOR]

Objective: To study the effect of shenfukang capsule combined with sodium ferulate on the inflammatory factors and immune function of patients with chronic glomemlonephritis. Methods: 78 patients with chronic glomerulonephritis who admitted in our hospital from February 2015 to January 2016 were divided into the observation group and the control group according to the random number method. The control group was treated with sodium ferulate, and the treatment group was treated with Shenfukang capsule combined with sodium ferulate. The clinical curative effect, serum inflammatory factors levels and immune function before and after treatment were compared between two groups. Results: After treatment, the total clinical efficacy of observation group was significantly higher than that of the control group (P ＜0.05). The serum serum levels of IL-6 observation group, TNF-α and hs-CRP, CD8 in the two groups were significantly higher than those before treatment, which were significantly lower in the observation group than those of the control group (P ＜0.05). After treatment, the levels of CD3, CD4 and CD4 / CD8 in the two groups were significantly higher than those before treatment (P ＜0.05), which were significantly higher in the observation group than those of the control group(P＜0.05). Conclusion: Shenfukang capsule combined with sodium ferulate could effectively relieve the inflammatory response and improve the immune function with good clinical curative effect in the treatment of chronic glomerulonephritis. [ABSTRACT FROM AUTHOR]