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Glioma is a common malignant tumor of the central nervous system. Although surgeries, combined with radiotherapy and chemotherapy, can improve patients'quality of life to some extent, the overall survival is still low due to tumor resistance, high mortality and recurrence rates, especially high-grade glioma (HGG), which is the leading cause of death in children and adults with brain tumors. In recent years, with the rise of tumor microenvironment research, it is discovered that tumor tissue and pericellular environment have a large impact on tumor development. This paper reviews the studies related to the neuron-associated tumor microenvironment in promoting glioma progression. [ABSTRACT FROM AUTHOR]

Geospatial data in databases have shifted to conform to the characteristics of big-data in tandem with the development of the Internet，mobile Internet，cloud computing，and especially，spatial data acquisition technologies. Faced with tackling spatial big data， traditional spatial database management techniques based on Relational Database Management Systems have encountered problems including the unstructured characteristics of the spatial object，the high scalability of storage capacity， and the high concurrency in big data application environment. This paper focuses on the mainstream of NoSQL databases that successfully deal with unstructured big data and are widely used in Internet applications ，but lack of spatial characteristics. The data operational and query modes cannot meet the requirments of GIS applications. T o resolve this problem ，this paper proposes a strategy that takes a NoSQL database as a warehouse for spatial big data and a traditional spatial database as the application server. The storage system architecture and the key technology and solutions are discussed. A prototype system was developed based on MongoDB，PostgreSQL and SQ Lite to verify the feasibility and effectiveness of the strategy. [ABSTRACT FROM AUTHOR]

目的 探讨维生素 D(Vit D)营养状态对反复呼吸道感染(RRTI)儿童免疫功能的影响。方法 选取RRTI患儿35例作为观察组,35例健康儿童作为对照组。采用凝集素亲和法检测骨碱性磷酸酶(BALP)、串联质谱法检测25-羟维生素D[25-(OH)D]、散射比浊法检测免疫球蛋白水平,并进行组间比较。观察组给予口服Vit D治疗,2个月后复查免疫球蛋白水平。观察组患儿随访6个月,观察呼吸道感染复发次数。结果观察组与对照组BALP值分别为(231.66±48.59)、(196.37±44.78)U/L,比较差异有统计学意义(t=3.16,P<0.01);其中观察组13例、对照组11例同时行25-(OH)D检测,分别为(25.46±5.01)nmol/L、(65.09±6.64)nmol/L,比较差异有统计学意义(t=16.66,P<0.01);两组Vit D缺乏亚临床状态发生率分别为17.14%(6/35)、14.29%(5/35),差异无统计学意义(χ2=0.11,P>0.05);佝偻病患病率分别为51.43%(18/35)、25.71%(9/35),比较差异有统计学意义(χ2=4.88,P<0.05);观察组治疗前Ig G、Ig A水平均显著低于对照组(t=5.01,P<0.01;t=12.42,P<0.01);观察组治疗后Ig G、Ig A水平均显著高于治疗前(t=3.37,P<0.01;t=8.87,P<0.01);观察组随访6个月,呼吸道感染反复次数为(1.09±0.66)次,较治疗前(4.60±1.44)次明显减少(t=13.14,P<0.01)。结论 Vit D缺乏可使患儿的免疫功能减低,补充足量的Vit D可提高其呼吸道的免疫功能,减少再次患呼吸道感染的概率。 [ABSTRACT FROM AUTHOR]

The Altay Mountains in China comprise an complete natural geographical complex. Its vertical zonation of natural geographical elements is significant and influences pollen transportation, deposition, and preservation. Based on the analysis of the pollen assemblages of 53 surface samples from the western Altay Mountains and species investigations in plant communities, the relationship between surface pollen and modern vegetation distribution in this region was determined using cluster and principal component analysis. The results showed that (1) The pollen assemblages in the surface soil of the western Altay Mountains were consistent with the distribution of modern vegetation, with unique pollen assemblages in each vegetation zone. Artemisia - Chenopodiaceae - Poaceae - Ephedra, Poaceae - Artemisia - Rosaceae - Chenopodiaceae, Picea (Picea + Abies) - Betula - Rosaceae - Poaceae - Cyperaceae, Betula - Poaceae - Salix - Cyperaceae, and Labiatae - Poaceae - Betula - Rosaceae - Cyperaceae pollen assemblages dominated the desert steppe, steppe scrub, mountain forest, subalpine shrub, and alpine meadow vegetation zones, respectively. Cluster analysis identified each vegetation zone accurately, and principal component analysis showed that humidity was the primary factor that controlled their distribution. (2) Picea, Abies, Rosaceae, Betula, Salix, Leguminosae, Ephedra, Poaceae, Artemisia, Chenopodiaceae, Compositae, Labiatae, Cyperaceae, and Thalictrum were the main pollen types in the western Altay Mountains, Picea and Betula were representative of this area, while Poaceae, Abies, and Cyperaceae were less. Chenopodiaceae and Artemisia were strongly representative. In addition to its own factors, pollen content may also be related to preservation conditions. [ABSTRACT FROM AUTHOR]

This article gives a review on domestic and foreign researches on the non-drug intervention for patients with perimenopausal depression published from 2012 to 2022, so as to provide a reference for clinical treatment and nursing. Currently, pharmacotherapy is the mainstay of treatment for perimenopausal depression, while many existing problems remain to be solved such as the variation in treatment effect and the difficulty in maintaining emotional stability. however, high safety and relatively low cost are the characteristics of non-drug intervention, so this article expounds on the non-drug intervention measures for perimenopausal depression, such as music therapy, dietary therapy, exercise therapy, acupuncture therapy and repetitive transcranial magnetic stimulation （rTMS）. [ABSTRACT FROM AUTHOR]

Aiming at the problems of large vibration quality, poor moisture performance and low work efficiency of traditional planar two-di-mensional vibrating screen, a new hydraulic vibration mode which could generate controllable multi-point excitation and multi-degree of freedom vibration in pipe network was proposed. A hydraulic vibration testing system based on pipe network excitation was developed. The simulation model based on AMESim was established. The effect of set pressure of relief valve, reversing frequency of rotary valve on excitation pressure and amplitude of piston rod were studied. Then, vibration test of the hydraulic excitation system was carried out by using displacement sensor, signal conditioner and data acquisition card, the vibration signal was filtered and smoothed. The results indicate that the excitation pressure increases with the rising system pressure, but decreases with the descent of the valve reversing frequency. Besides, the amplitude of piston rod increases with the rising system pressure but decreases with the descent of the valve reversing frequency. The measured vibration curves basically coincide with the simulation curves, which reveals the coupling relationship among the reversing frequency of the rotary valve, the system pressure, and the cylinder amplitude, indicates the controllability of the hydraulic excitation parameters, demonstrates the feasibility of exciting the pipe network to generate multi-point excitation and multi-degree-of-freedom vibration. The pipe network hydraulic excitation system model based on AMESim can truly reveal the dynamic characteristics of the system, which provides a new way for the design and analysis of the hydraulic excitation system. [ABSTRACT FROM AUTHOR]

[ Objective) This paper aimed to the quantification of the detailed ranges and dynamics of the environmental factors of the light, temperature, air and moisture in morel cultivation. ( Methods ] Environmental factors in greenhouses for Morchella importuna cultivation were collected in Chengdu plain area using Internet of Things (IoT) technologies. Illumination intensity, air temperature, air relative humidity, oxygen percentage in the air, carbon dioxide concentration in the air, soil temperature and soil water content were recorded every ten mi nutes, in greenhouses with different layers of sunshade-net. Fluctuation models in 24-hour cycle were established for the environmental fac tors at different stages. [ Results] The sunlight in the greenhouses showed a dynamic that indirectly regulated the fluctuating features of the ox Oxygen percentage, relative humidity and temperature in the air, while the average illumination intensity in the greenhouse with the highest mo rel yield were about 2500 - 3500 ks at the noon of sunny days. Sunshade-net effectively prevented over-heating during daytime and over-chill ing during night., diminishing the occurrence of extreme values of air temperature and soil temperature, whereas the cumulative temperatures of the air and the soil, as well as the cumulative values of the relative humidity. oxygen percentage and carbon dioxide concentration in the air, and the soil water content, showed no significant difference between the regimes of different sunshade net layers. The effects of the sunshade-net layers were attenus ting the fluctuations of the environmental factors, The air tem perature was either higher than or similar to the soil temperature during the fruiting stage. (Conclusion) Field conditions ideal for morel cultivation were summarized from the analytical results of the environmental factors, for the reference of field management of morel cul tivation in plain area of southwestern China, which further provided some inspirations for the engineers hoping to develop factory-mode tech nologies of morel production. [ABSTRACT FROM AUTHOR]