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在新的分数阶导数定义下，运用Bohnenblust-Karlin不动点定理并结合上下解方法研究了一类分数阶非线性微分包含初值问题的可解性.其中，F：J × R → 2R是一个L1-Carathéodary函数，x(α)(t)表示x在t上的α阶导数，α∈（0，1].最后，分别给出了当集值映射F关于第二变量x次线性和至多线性增长时解的存在结果.

OBJECTIVE: To systematically evaluate the efficacy and safety of formula granules of Liangfu pill in the treatment of epigastric pain. METHODS: PubMed, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, CNKI, VIP and CBM were retrieved to collect the randomized controlled trials (RCT) of formula granules of Liangfu pill in the treatment of epigastric pain till Feb. 10th, 2022. Stata 12. 0 software was used to perform Meta-analysis on outcome indicators such as the total effective rate and recovery rate, the pain degree, duration and number of episodes of epigastric pain, and the safety was evaluated. RESULTS: Totally 11 RCT were enrolled, including 1 056 patients. Meta-analysis showed that compared with Liangfu pill decoction, formula granules of Liangfu pill could significantly improve the cure rate and overall effective rate of patients with epigastric pain ( cure rate: RR = 0. 74, 95% CI = 0. 65-0. 84; total effective rate: RR = 0. 87, 95% CI = 0. 83-0. 91 ), the differences were statistically significant(P < 0. 05). Compared with decoction, formula granules of Liangfu pill was more effective in improving the pain degree, duration and frequency of epigastric pain ( pain degree: RR = 0. 86, 95%CI = 0. 71-1. 02; duration of pain: RR = 0. 89,95%CI = 0. 74-1. 04; frequency of pain: RR = 0. 69,95%CI = 0. 54- 0. 84), the differences were statistically significant(P < 0. 05). Meanwhile, compared with Liangfu pill decoction, formula granules of Liangfu pill could significantly reduce the overall incidence of adverse drug reactions in patients, the difference was statistically significant(RR = 0. 41,95%CI = 0. 19-0. 88,P<0. 05). CONCLUSIONS: Compared with Liangfu pill decoction, formula granules of Liangfu pill in the treatment of patients with epigastric pain can further improve the overall efficacy and relieve pain. Limited by the quality of the included literature and the number of samples, the above conclusions still need to be verified by more high-quality, multicenter and large-sample RCT. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Experimental Technology & Management is the property of Experimental Technology & Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Test & Measurement Technology is the property of Publishing Center of North University of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To discuss the temperature regulation nurse of premature infants with jaundice treated by blue light in the incubator. Methods From the premature infants admitted to the hospital from January 2018 to August 2019,80 premature infants diagnosed with jaundice and meeting the inclusion criteria were randomly divided into the control group and the observation group, 40 cases each. Children in the control group were directly treated with blue light in the incubator, while those in the observation group were treated with blue light and nursed with temperature regulation. The rising trends of body temperature, adverse event rate and treatment prognosis were compared. Results After routine blue light treatment and temperature regulation for 3 days, the serum total bilirubin decreased, length of stay and quiet sleep time in the observation group were significantly better than those in the control group, with statistically significant differences (P< 0.05 ). At the beginning of blue light treatment, there was no difference in body temperature between the two groups . From 2 to 12 h after blue light irradiation,the body temperature of the observation group did not rise as much as that of the control group, and the average body temperature in each period was lower than that of the control group, with statistically significant differences (P< 0.05). The incidence of adverse reactions during photo therapy in the observation group was significantly lower than that in the control group, and the difference was statistically significant (P < 0.05) . Conclusion Before the premature jaundice children receive blue light treatment to take temperature measurement, the implementation of temperature regulation nursing, can effectively improve the treatment effect, stabilize the temperature level, effectively reduce the incidence of adverse reactions, to promote the recovery of premature infants, improve the prognosis has important clinical significance, which is worth promoting. [ABSTRACT FROM AUTHOR]

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To investigate the application rationality of antibiotics in Shenzhen Yantian District People's Hospital (hereinafter referred to as " our hospital"), so as to provide reference for standardization of application of antibiotics and establishment of effective intervention measures. METHODS: From 2015 to 2016,10％ medical records were selected randomly from 14 clinical departments in each month (1 150 cases in 2015, 1 139 cases in 2016), with a total of 2 289 cases. Analysis was conducted on application rationality of antibiotics. RESULTS: In 2015 and 2016, the top three departments ranked by number of medical orders were respectively department of pediatrics, obstetrics and respiration medicine;the application rate of antibiotics was 100.00％, with medical orders of 695 and 637 cases. Irrational medical orders were respectively 182 and 125 cases. Compared with 2015, the irrational application rate of antibiotics in type Ⅰ, Ⅱ and Ⅲ incision decreased significantly. The irrational types of medical orders of perioperative prophylactic application of antibiotics mainly performed as improper administration occasion, irrational treatment course, improper drug selection and improper indications. The main types of irrational medical orders of therapeutic application of antibiotics were respectively inappropriate usage and dosage, inappropriate indications, over level of application of antibiotics and improper selection pf drugs. CONCLUSIONS: There are some irrational phenomenon in application of antibiotics in our hospital, after intervention, the level of rational drug application has been increased. The clinicians are suppose to actively play their own advantages and promote the rational drug application in clinic. [ABSTRACT FROM AUTHOR]

Objective: To explore the role of fibroblast growth factor 23 (FGF23) in patients with end-stage renal disease. Methods: 58 cases with end stage renal disease who were treated in our hospital from February 2013 to May 2015 were selected and according to the iPTH values, the patients were divided into two groups: iPTH > 300 pg / mL as the observation group. 150 pg inL< iPHT2 300 pg inL as the control group, with 29 patients in each group. Then the calcium, phosphorus, albumin, blood lipids, and levels of FGF23. iPTH. 1.25 （OH)2D3 in the two groups were observed and compared. Results: The levels of FGF23 and iPTH in the observation group were significantly higher than those of the control group, and the differences were statistically significant (P<0.05). Compared with the control group, the blood urea nitrogen, creatinine and dialysis in the observation group significantly decreased, and the difference was statistically significant (P< 0.01): The FGF23 and iPTH decreased in the two groups, and the difference was statistically significant (P < 0.01). 1.25 （OH)2D3 and serum albumin level were the independent influencing factors of FGF23 Log. Conclusion: FGF23 plays a role in the pathogenesis of secondary parathyroid function in patients with end-stage renal disease. [ABSTRACT FROM AUTHOR]