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Copyright of Journal of Sichuan University (Medical Science Edition) is the property of Editorial Board of Journal of Sichuan University (Medical Sciences) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To identify the risk factors of the incidence rate of initial poor graft function (IPGF) in recipients after living donor liver transplantation. Methods Clinical data of 309 patients undergoing living donor liver transplantation were retrospectively analyzed Candidate risk factors; (1) donor factors included age, gender and body mass index (BMI); (2) recipient factors included age, gender, BMI and preoperative Child-Pugh classification, model for end-stage liver disease (MELD) grading, preoperative renal insufficiency, serum total bilirubin elevation, hyponatremia and hypopotassaemia; (3) graft factors included graft cold ischemia time, graft recipient weight ratio (GRWR); (4) recipient surgery factors included total operation time, blood loss volume, blood transfusion volume, platelet transfusion and anhepatic phase ⩾100 min. Single factor analysis was performed to identify the potential risk factors of IPGF. Logistic regression analysis was conducted to explore independent risk factors. Results and Conclusions Child-Pugh C of preoperative recipient liver function, MELD score ⩾20, serum total bilirubin elevation (>68.4 μmol/L), hyponatremia(<135 mmol/L), hypopotassaemia (<3.5 mmol/L) and anhepatic phase ⩾100 min were potential risk factors of IPGF (all P<0.05). Child-Pugh C of preoperative recipient liver function was an independent risk factor of the incidence rate of IPGF following living donor liver transplantation (P=0.019). [ABSTRACT FROM AUTHOR]

Objective To summarize the clinical experience and effect analysis of liver transplantation from donation after citizen's death. Methods Clinical data of 76 donors and 78 recipients of liver transplantation from donation after citizen's death completed in Liver Transplantation Center of West China Hospital, Sichuan University from March 2012 to November 2015 were analyzed retrospectively. The functional recovery of early allografts in liver transplant recipients was observed and the risk factors causing early allograft dysfunction (EAD) were analyzed. In addition, long-term survival of allografts and recipient as well as complications was observed. Results The incidence of postoperative EAD was 36% (28 /78) in 78 recipients. High total bilirubin (TB) and long cold ischemia time constituted the risk factors of EAD. Survival rate of the recipients was 92% (72 /78) during perioperation, and 6 cases died, of which 4 cases died of primary graft dysfunction, 1 case of upper gastrointestinal hemorrhage and 1 case of pulmonary infection. Postoperative abdominal infection occurred in 5 cases, with biliary stricture in 3 cases and vascular thrombosis in 2 cases. One case died, and the rest were improved after corresponding treatment. The 1-year survival rate of the recipients was 84.2% and 2-year survival rate was 80% after operation. Conclusions Liver transplantation from donation after citizen's death realizes favorable short and long-term effects, which can be regarded as a good source of donor livers. Important measures such as controlling the preoperative quality of donor liver and shortening the cold ischemia time can improve the clinical effect. [ABSTRACT FROM AUTHOR]