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为评价红棕榈油作为烹调用油的安全性，按照GB 15193.22—2014《食品安全国家标准28天经口毒性试验》对马来西亚产红棕榈油进行短期毒性试验。将100只SD大鼠分为5组，按照人体摄入量的5.12、10.24、20.48倍设置红棕榈油低、中、高剂量组，同时设置溶剂对照组（玉米油组）和阴性对照组（棕榈油组）。采用掺入饲料和经口灌胃两种方式同时连续给予大鼠红棕榈油28 d，每天观察大鼠临床表现，每周记录体质量、摄食量，计算食物利用率等指标，试验前和结束时对大鼠进行眼部检查，结束时进行血液学、血生化、尿常规检测，并进行大体解剖，计算脏器系数并进行组织病理学检查。结果表明，红棕榈油以雌性2.04、4.11、8.31 g/kg，雄性2.12、4.23、8.45 g/kg的实际剂量给予大鼠28 d，受试大鼠临床表现良好，体质量、食物利用率、脏器质量、脏器系数均无异常改变；血液学、血生化及尿常规指标均在正常范围；各脏器病理组织学检查均未见与受试样品有关的病理改变。短期毒性试验结果表明红棕榈油未对大鼠产生毒性效应，短期经口食用是安全的。 In order to evaluate the safety of red palm oil as cooking oil, the short-term toxicity test of red palm oil from Malaysia was conducted by GB 15193.22-2014 National food safety standard 28-day oral toxicity test. A total of 100 SD rats were devided into 5 groups, and the high, medium, low dose groups of red palm oil were set according to 20.48, 10.24, 5.12 times of human intake. Solvent control group (corn oil group) and negative control group (palm oil group) were also set. The rats were given both adulterated feed and oral gavage for 28 d. The clinical performance of the rats was observed daily, body weight and food intake were recorded weekly, and food utilization was calculated. Before and at the end of the test, rats′ eyes were examed. At the end of the test, the tests of hematology, blood biochemistry, routine urine, gross anatomy and histopathological examination were carried out on the main organs, and the organ coefficient was calculated. The results showed that giving red palm oil at the real dose of female 2.04, 4.11 g/kg and 8.31 g/kg and male rats 2.12, 4.23 g/kg and 8.45 g/kg for 28 d, the experimental rats were in good clinical performance, with no abnormal changes in body weight, food utilization, organ weight and organ coefficient. The results of hematology and biochemistry and routine urine indexes were within the normal range. The histopathological examination of each organ showed no pathological changes related to the tested sample.The red palm oil has no harmful effects on rat, and is safe for orally intake in a short period of time.

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Copyright of Chinese Medical Equipment Journal is the property of Chinese Medical Equipment Journal Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Feed Industry is the property of Liaoning Provincial Institute of Agricultural Mechanization and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Ferroptosis suppressor protein 1 (FSP1) is a key suppressor in the process of ferroptosis, which can prevent cell death and has important biological functions and potential value in clinical application. In this article, the discovery background, gene localization and structural characteristics of FSP1, as well as its dual role in inhibiting ferroptosis and promoting apoptosis were explicitly discussed. In clinical researches, FSP1 inhibitors, such as iFSP1 and icFSP1, have been developed. Subsequently, the regulatory mechanisms of FSP1 expression, its association with tumor immune escape, and its potential as a monitoring indicator for tumor prognosis and therapeutic response will be investigated. [ABSTRACT FROM AUTHOR]

Copyright of China Brewing is the property of China Brewing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aim: To analyze the influencing factors of adverse cardiovascular events in elderly patients with acute ST-segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI), and to establish a nomogram prediction model. Methods: A total of 216 elderly patients with acute STEMI who underwent PCI in Jinqiu Hospital of Liaoning Province from February 2021 to January 2023 were selected and divided into occurrence group (n = 33) and non-occurrence group (n = 183) according to the occurrence of postoperative adverse cardiovascular events. General data, laboratory indicators, imaging information, and postoperative medication data of all patients were collected. Univariate and multivariate Logistic regression analysis were used to explore independent risk factors for adverse cardiovascular events. A nomogram prediction model was constructed according to independent risk factors of neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), C-reactive protein/albumin ratio (CAR), C-reactive protein to high density lipoprotein cholesterol ratio (CHR), calibration curve was drawn to verify the nomogram model, and receiver operating characteristic (ROC) curve was drawn to analyze the predictive efficacy of the predictive model for column line diagrams. Results The levels of NLR, PLR, CAR, CHR, Gensini score, and platelet aggregation ratio (PAR) were significantly higher in occurrence group than those in non-occurrence group, left ventricular ejection fraction(LVEF) was significantly lower in occurrence group (P<0. 05). Logistic regression analysis showed that Gensini score, LVEF, PAR, NLR, PLR, CAR and CHR were independent risk factors for adverse cardiovascular events after PCI in elderly acute STEMI patients (P<0. 05). The column-line diagram model for predicting the risk of adverse cardiac events after PCI in elderly acute STEMI patients was constructed based on independent risk factors, and the calibration curve of the model was close to the ideal model, and the ROC curve showed that the area under the ROC curve for the prediction of the risk of adverse cardiovascular events in the elderly acute STEMI patients was 0. 914. Conclusion NLR, PLR, CAR and CHR are independent risk factors for adverse cardiovascular events in elderly acute STEMI patients after PCI, and the nomogram model constructed based on these factors can effectively predict the risk of adverse cardiovascular events in elderly acute STEMI patients after PCI. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Immunology is the property of Medical Periodical Society of Jilin and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Obstetrics & Gynecology is the property of TianJin Medical Information Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Intelligent Agriculture Mechanization is the property of Nanjing Institute of Agricultural Mechanization and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Qing History Journal is the property of Renmin University of China, Institute of Qing History and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Agricultural Outlook (1673-3908) is the property of Institute of Agricultural Information, Chinese Academy of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Clean Coal Technology is the property of Clean Coal Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Science & Technology & Economy is the property of Grain Science & Technology & Economy Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Plastics Science & Technology / Suliao Ke-Ji is the property of Plastics Science & Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Diabetes belongs to the category of “diabetes” in traditional Chinese medicine. According to the development process and clinical manifestations of the disease, there are often different syndrome manifestations. In most cases, excessive heat mainly appears in the early stage, which is called excessive heat type diabetes, and deficiency of both qi and yin is mainly present in the middle and late stages, which is called deficiency of both qi and yin type diabetes. OBJECTIVE: To establish a mouse model of interior heat and diabetes by compound method, which can reflect the characteristics of traditional Chinese medicine symptoms, and lay a foundation for studying the evolution of diabetes and related drugs. METHODS: Thirty ICR mice were randomly divided into blank control group, short-term model group and long-term model group. The short-term model group was intraperitoneally injected with 40 mg/kg streptozotocin for 5 consecutive days, and then given 20 g/kg warm drugs via gavage for 14 days to establish the interior heat and diabetes model. On the basis of short-term models, the long-term model group was given the same dose of warm drugs for 21 days. The body mass, fasting blood glucose, water intake, food intake, urine volume and serum insulin levels of mice in each group were measured after modeling. Insulin resistance index and insulin sensitivity index were calculated. The activities of mitochondrial respiratory chain complexes III and V in liver and kidney tissues were measured. Hematoxylin-eosin staining was used to detect the pathological changes of mouse pancreas. The study protocol was approved by the Animal Ethics Committee of Henan University of Chinese Medicine (approval No. DWLL202003270). RESULTS AND CONCLUSION: Compared with the blank control group, the mice in the short-term and long-term model groups showed typical symptoms of diabetes, such as polydipsia, polyuria, body mass loss, rise in the rectal temperature (P < 0.05); the levels of fasting blood glucose and insulin resistance index were significantly increased; the levels of insulin sensitivity index were significantly decreased (P < 0.05); and the activities of mitochondrial respiratory chain complexes III and V in liver and kidney tissues were significantly increased (P < 0.05). The pancreatic tissue of mice in the short-term and long-term model groups was damaged in varying degrees by pathological observation of the pancreas. Compared with the short-term model group, the long-term model group had more drinking, more food, more urine, slower growth of body mass, and significantly lower rectal temperature with the progression of the disease (P < 0.05); the levels of fasting blood glucose and insulin resistance index were significantly increased, while the levels of insulin sensitivity index were significantly decreased (P < 0.05); the activities of mitochondrial respiratory chain complexes III and V in liver and kidney tissues were significantly decreased (P < 0.05). Pathological findings indicated that the pancreatic function was further damaged in the long-term model group as the disease progressed. To conclude, the combination of streptozotocin and warm drugs for modeling can improve the disease-syndrome further combination model of interior heat and diabetes, and in the model, the syndrome is evolved. The short-term model shows excessive heat and the long-term model shows deficiency of both qi and yin. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Shanghai Physical Education Institute / Shanghai Tiyu Xueyuan Xuebao is the property of Shanghai Physical Education Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Clean Coal Technology is the property of Clean Coal Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)