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BACKGROUND: Previous studies have shown that knee joint moment changes in patients with knee osteoarthritis, but there are few reports on the correlation of moment changes with knee extensor muscle strength and gait spatiotemporal parameters. OBJECTIVE: To explore the correlation of knee extensor muscle strength and gait spatiotemporal parameters with peak knee flexion moment and knee adduction moment in female patients with knee osteoarthritis. METHODS: Twenty knee osteoarthritis female patients with single knee disease hospitalized in Guizhou Hospital, Beijing Jishuitan Hospital from February to August 2022 were selected as the knee osteoarthritis group, and an additional 20 healthy females without musculoskeletal disease were selected as the control group. The knee extensor force at 60 (°)/s was measured with the Biodex isokinetic instrument. The gait spatiotemporal parameters and peak knee flexion moment and knee adduction moment were collected with the Italian BTS infrared motion capture system and force measuring platform. Pearson correlation analysis was used to explore the correlation of muscle strength and gait spatiotemporal parameters with peak knee adduction moment and knee flexion moment, and the variables significantly related to knee joint moment were further included in the multiple stepwise regression analysis. RESULTS AND CONCLUSION: (1) Compared with the control group, the knee osteoarthritis group had significantly lower knee extensor force, step speed, step frequency, step length, step width, peak knee adduction moment and knee flexion moment at 60 (°)/s (P < 0.05). (2) Pearson correlation analysis showed that the 60 (°)/s centripetal extensor force, step speed, step frequency and step length were positively correlated with the peak knee flexion moment, and negatively correlated with the peak knee adduction moment, with a statistically significant difference (P < 0.05). (3) The results of multiple stepwise regression showed that step speed and 60 (°)/s knee extensor force were the strongest predictors of peak knee flexion moment, and the total R² value of the two factors was 0.426, indicating that 42.6% of the total variance of this parameter could be explained. Step length and 60 (°)/s centripetal extensor force were the strongest predictors of peak knee adduction moment. The total R² value of the two factors was 0.602, indicating that 60.2% of the total variance of this parameter could be explained. (4) It is concluded that knee extensor strength, step speed and step length are the main variables affecting peak knee adduction moment and knee flexion moment. Therefore, these variables can be used for clinical gait monitoring and guidance to change knee joint load during knee osteoarthritis rehabilitation. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Irrigation & Drainage is the property of Journal of Irrigation & Drainage Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective:To analyze the influences of secreted protein acidic and rich in cysteines-like protein 1 (SPARCL1) on the proliferation,apoptosis and invasion of non-small cell lung cancer (NSCLC) cells,and to explore the role of Mitogen activation inhibitor(MEK)/Extracellular regulated protein kinase (ERK) pathway in it.Methods:From September 2019 to June 2021,the cancer tissues and corresponding adjacent tissues of 84 NSCLC patients who received surgical treatment in our hospital were collected,real time quantitative reverse transcription polymerase chain reaction (qRT-PCR) method was applied to measure and compare the expression level of SPARCL1 messenger RNA (m RNA) in tissues and normal lung epithelial cells HBEpiC and NSCLC cells A549,HCC827,H1299 and H292.A549 and HCC827 were selected for culture and grouping,they were divided into control group,NC si RNA group,SPARCL1si RNA group,U0126 group (MEK/ERK specific inhibitor),and SPARCL1 si RNA plus U0126 group.Cell counting kit 8 (CCK8) method and the plate cloning method were used to measure the proliferation of A549 and HCC827 cells,flow cytometry was applied to determine the apoptosis of A549 and HCC827 cells,Transwell chamber method was applied to determine the invasive ability of A549 and HCC827cells,Western blot was applied to detect the protein expression of SPARCL1,p-MEK,MEK,p-ERK1/2,ERK1/2.Results:The SPAR-CL1 m RNA expression level in NSCLC tissues was lower than that in adjacent tissues (P＜0.05).Compared with HBEpiC cells,the SPARCL1 m RNA expression level in NSCLC cells A549,HCC827,H1299 and H292 cells decreased (P＜0.05).Compared with the control group,the SPARCL1 m RNA expression level,protein expression and apoptosis rate of A549 and HCC827 cells in SPARCL1 si RNA group decreased (P＜0.05),the OD450,number of colonies formed,number of invasive cells,p-MEK/MEK,and p-ERK1/2/ERK1/2 protein expression increased (P＜0.05),the SPARCL1 m RNA expression level,protein expression and apoptosis rate of A549 and HCC827 cells in the U0126 group increased (P＜0.05),the OD450,number of colonies formed,number of invasive cells,p-MEK/MEK,and p-ERK1/2/ERK1/2 protein expression decreased(P＜0.05).Compared with the SPARCL1 si RNA group,the SPARCL1 m RNA expression level,protein expression and apoptosis rate of A549 and HCC827 cells in SPARCL1 si RNA plus U0126 group increased (P＜0.05),the OD450,number of colonies formed,number of invasive cells,p-MEK/MEK,and p-ERK1/2/ERK1/2 protein expression decreased (P＜0.05)Conclusion:SPARCL1 may affect the proliferation,invasion and apoptosis of A549 and HCC827 cells by regulating MEK/ERK pathway. [ABSTRACT FROM AUTHOR]

Copyright of Information & Control is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mycosystema is the property of Mycosystema Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Guangxi Normal University - Natural Science Edition is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Guangxi Normal University - Natural Science Edition is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Environmental Science & Technology (10036504) is the property of Editorial Board of Environmental Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal on Communication / Tongxin Xuebao is the property of Journal on Communications Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Interferometric synthetic aperture radar( In SAR) has become one of the key technologies to obtain highprecision Digital Orthophoto Map( DOM) and Digital Surface Model( DSM).It is not affected by weather conditions and can acquire data in all day and weather conditions. Airborne dual-antenna millimeter-wave InSAR is independent of loss-of-correlation which has the characteristics of small size,high resolution,high flexibility,etc.And it can obtain large-scale and high-precision images.This paper uses airborne dual-antenna millimeter-wave InSAR to acquire high-precision DOM and DSM in Shibing experimental area of Guizhou( mountainous) and Qionglai experimental area of Sichuan( alpine) through interference processing,block adjustment,geocoding,and image mosaic.Besides,the ground control points( GCPs) are used to verify the accuracy. The results show that the accuracy of DSM obtained meets the requirement of 1: 5000 terrain mapping.It has been proven that the airborne dual-antenna millimeter-wave InSAR has the ability to generate DOM/DSM with different terrains,which provides a new technical means for solving the lack of DOM/DSM data in tough areas. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of China University of Petroleum is the property of China University of Petroleum and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Natural Gas Geoscience is the property of Natural Gas Geoscience and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Petroleum Geology & Recovery Efficiency is the property of Petroleum Geology & Recovery Efficiency and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to study the pyrolysis behavior of loquat leaf extract that pyrolysates effect to the component of cigarette smoke,the pyrolysates were investigated in N2,N2 containing 10% O2 and at three temperature levels of 300 °C,600 °C and 900 °C,respectively. The pyrolysates were directly introduced into GCMS,qualitative analysis of the pyrolysates by mass spectrometry,and a semi-quantitative analysis by area normalization were made. The results showed that loquat leaf extract anaerobic pyrolysis products were mainly the aldehydes,alcohols and phenols,and aerobic pyrolysis products were mainly carboxylic acids,ketones and phenols,etc. The pyrolysis products could produce grassy,spicy,fragrant baked,caramel aroma,nutty aroma,sweet,floral and other rhyme tune,which could enrich the aroma of cigarettes. The amount of these pyrolysates under aerobic conditions was more than anaerobic pyrolysates,the oxygen introduced could exacerbate the pyrolysis of loquat leaf extract. With the increase of temperature,pyrolysis wasmore and more complex,benzenes and polycyclic aromatic hydrocarbons substances released was found to inerease. [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A double-ring truss deployable antenna mechanism, which is used as the support and deployment mechanism for large-diameter space-borne antenna, is proposed to improve the stiffness of the single-ring truss deployable antenna with large diameter. The structural decomposition of double-ring truss deployable antenna mechanism is conducted, the screw constraint topology graph of the closed-loop deployable mechanism unit is drawn, and the degree of freedom (DOF) of the mechanism is analyzed. The analyzed result shows that the double-ring truss deployable mechanism has only one DOF. The screw velocity of each component in the mechanism is analyzed based on screw theory, the angular velocity and centroid linear velocity of each component are obtained through vector operation, and the Jacobian matrixes are also obtained. Furthermore, the screw accelerations of the components in the mechanism are derived based on the screw derivative, and the angular acceleration and centroid linear acceleration of each component in the double-ring truss mechanism are obtained. A dynamic model of the double-ring truss mechanism is established based on Newton-Euler equation and virtual work principle, and the numerical calculation and simulation verification are carried out. The research results show that the theoretical analysis is correct. The proposed double-ring truss deployable antenna mechanism has a simple structure, and can be smoothly deployed with only one input drive, the kinematic and dynamic analysis method based on screw theory used in this paper has a clear physical meaning, the analysis process is relatively stylized and is easy to program. [ABSTRACT FROM AUTHOR]