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Copyright of Plateau Meteorology is the property of Plateau Meteorology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Arid Land Geography is the property of Chinese Academy of Sciences, Xinjiang Institute of Ecology & Geography and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To explore the molecular mechanism of miR-194-5p targeting down regulation of CD44 and inhibiting epithelial mesenchymal transition (EMT) in gastric cancer stem cells (CSCs). Methods: qRT-PCR was used to detect the expression levels of miR-194-5p, CD44, Snail, and membrane matrix metalloproteinase-1 (MT1-MMP) in gastric adenocarcinoma cell lines (SGC-7901, MGC-803, SPAG-9, and MNK-45) and gastric mucosal cells (GES-1). Western blot was used to detect the expression levels of CD44, Snail, and MT1-MMP proteins. miR-194-5p over-expression and low-expression plasmid vectors were constructed in vitro then to transfect with lentivirus. The experiment was divided into over-expression group, control group, and low-expression group. qRT-PCR and Western blot were used to detect changes of miR-194-5p, CD44, Snail, and MT1-MMP; CCK8 assay was used to detect cell proliferation rate, flow cytometry was used to detect cell apoptosis rate, Transwell assay was used to detect cell invasiveness, and Western blot was used to detect the expression levels of EMT markers E-cadherin and N-cadherin proteins. Results: The expression of miR-194-5p was significantly lower in gastric adenocarcinoma cell lines than gastric mucosal cells, while the expression levels of CD44, Snail, and MT1-MMP were significantly higher; what's more, the expression differences of SGC-7901 and MGC-803 compared to gastric mucosal cells were the most (P<0.05). Compared with the control group, miR-194-5p expression in the over-expression group was significantly more, but CD44, Snail, and MT1-MMP expressions were significantly less, cell proliferation and invasiveness were lower, apoptosis rate was higher, E-cadherin was upregulated, and N-cadherin was downregulated (P<0.05). Compared with the control group, the expression level of miR-194-5p was significantly lower in the low-expression group, while the expression levels of CD44, Snail, and MT1-MMP were significantly higher, the cell proliferation rate and invasiveness were more, while the apoptosis rate was less, E-cadherin was down-regulated, and N-cadherin was upregulated (P<0.05). Conclusion: Low expression of miR-194-5p in gastric cancer may exert an anti-tu-mor effect by downregulating the expression of CD44 in CSCs, thereby inhibiting the occurrence of EMT. [ABSTRACT FROM AUTHOR]

Copyright of Food & Fermentation Industries is the property of Food & Fermentation Industries and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food & Fermentation Industries is the property of Food & Fermentation Industries and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Arid Land Geography is the property of Chinese Academy of Sciences, Xinjiang Institute of Ecology & Geography and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Geomatics & Information Science of Wuhan University is the property of Geomatics & Information Science of Wuhan University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

[Abstract] Objective To investigate the short-term efficacy of laparoscopic-assisted gastric cancer surgery in obese patients and the expression of human epidermal growth factor receptor 2 (HER2), and to provide some insights for promoting the surgical treatment of obese gastric cancer patients. Methods The clinical data of 82 cases with gastric cancer who underwent laparoscopic-assisted radical gastrectomy in the Department of General Surgery of the Xiaolan Hospital Affiliated of Southern Medical University from January 2015 to June 2019 were collected retrospectively, and they were divided into the obese group (BMI 25 kg/m2,30 cases) and the non-obese group (BMI<25 kg/m²,52 cases). The indexes of operation-related and postoperative recovery were compared between the two groups, and the influence of obesity on HER2 expression was discussed. Results The operation time of obese patients (330. 10±61, 86) min was significantly longer than that of nonobese patients (296. 37±72. 23) min and the proportion of patients with intestinal type, diffuse type and mixed type classified by Lauren [60. 0% (18/30), 30.0% (9/30) and 10.0% (3/30), respectively] was significantly higher than that of non-obese group [30.7% (16/52), 55.8% (29/52) and 13.5% (7/52), respectively]. The differences were statistically significant (P<0.05). There were no significant differences in intraoperative blood loss (366. 16±98. 55) mL, number of lymph node dissection (21. 56±3.23), postoperative recovery time of exhaust(3.37±0.75)d, postoperative eating time(3. 58±0.45) d, postoperative indwelling time of drainage tube(7.08±1.89) d, postoperative complication rate [23.3% (7/30)], and postoperative hospitalization time (10.73±2. 37)d compared with that of non-obese group [(337. 12±97. 22) mL, (22.67±3.61) pieces, (3.20± 0.73)d, (3.74±0.47)d,7. 21±1. 45)d, (10. 23±2. 71)d, 28.8% (15/52), respectively]. The positive rate of HER2 in the obese group was lower than that in the non-obese group (10% vs. 15. 4%, P > 0.05). Conclusion When BMI 25 kg/m² is taken as the criterion for obesity, the results of current samples cannot exclude the influence of obesity on the expression of HER2 in gastric cancer. The operation time of obese pa- tients assisted by laparoscopy is longer. Intraoperative anatomy should adhere to the principle of individuality, but not affect recent postoperative recovery. [ABSTRACT FROM AUTHOR]

Copyright of Bulletin of Soil & Water Conservation is the property of Bulletin of Soil & Water Conservation Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the effects of laparoscopic preperitoneal hernia repair (TAPP) and Lichtenstein hernia repair for inguinal hernia on serum testosterone concentration and matrix metalloproteinase-2 (MMP-2). Methods: From January 2017 to January 2021, 80 patients with inguinal hernia were selected, and they were divided into TAPP group (n=44) and Lichtenstein group (n=36) by random number table, and the two groups of surgical indicators and surgery were recorded. For post-operative complications and recurrence rates, serum testosterone and MMP-2 levels were measured before and 1 month after surgery. Results: The amount of intraoperative blood loss and postoperative anal exhaust time in TAPP group were lower than those in Lichtenstein group (P<0.05), and there was no difference in the operative time between the two groups (P>0.05). The postoperative hospital stay in TAPP group was shorter than that in Lichtenstein group, and the hospitalization cost was higher than that in Lichtenstein group (P<0.05). There was no difference in postoperative recurrence rate between the two groups (P>0.05). The incidence of scrotal edema in TAPP group was lower than that in Lichtenstein group (P<0.05), but there was no difference in other complications among groups (P>0.05). There was no change in serum testosterone in both groups before and after operation (P<0.05). The level of MMP-2 in both groups was decreased after surgery (P<0.05), but there was no difference between groups (P>0.05). Conclusion: Both surgical methods have no damage to the testicular function of patients with inguinal hernia, and both can effectively reduce the serum MMP-2 level, prevent the recurrence of the inguinal hernia, and are safe and effective. In contrast, the laparoscopic ATPP has less trauma and the operation The recovery is faster, but the operation is more difficult and costly. The two surgical methods have their own advantages and disadvantages. The surgical method needs to be selected according to the actual situation of the patient. [ABSTRACT FROM AUTHOR]

Copyright of International Architecture is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Natural Gas Industry is the property of Natural Gas Industry Journal Agency and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Information & Control is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Arid Zone Research / Ganhanqu Yanjiu is the property of Arid Zone Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Harbin Institute of Technology. Social Sciences Edition / Haerbin Gongye Daxue Xuebao. Shehui Kexue Ban is the property of Harbin Institute of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)