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BACKGROUND: Pro-kin balance system guidance has a relatively excellent rehabilitation effect on lower extremity proprioception and trunk control in stroke patients, but its effect on knee proprioception and balance function in patients after anterior cruciate ligament reconstruction has been less reported. OBJECTIVE: To investigate the effect of rehabilitation training guided by Pro-kin balance system on proprioception and balance function of the affected knee after anterior cruciate ligament reconstruction. METHODS: A total of 84 patients who underwent anterior cruciate ligament rupture reconstruction surgery were randomly divided into observation group and control group, with 42 patients in each group. The patients in the control group received routine rehabilitation intervention after surgery, and those in the observation group were given rehabilitation training based on the guidance of Pro-kin balance system. The training in each group lasted for 8 weeks. Lysholm score and International Knee Documentation Committee score were used to evaluate the change of knee joint function before and after the intervention. Average weight-bearing strength difference, trajectory error, swing value and 30°, 45° and 60° passive angulation errors of the affected knee joint were used to evaluate the changes in the proprioception of the affected knee. The area and length of motion trajectory under open and closed eyes were used to evaluate the change of balance function. The satisfaction of patients in both groups with this rehabilitation training was investigated. RESULTS AND CONCLUSION: After training, Lysholm score and International Knee Documentation Committee score of patients in both groups were significantly higher than those before training (P < 0.01), and the above scores in the observation group were significantly higher than those in the control group (P < 0.01). After training, the average weight-bearing strength difference, trajectory error and swing value of the two groups were significantly lower than those before training (P < 0.01), and the above scores in the observation group were significantly lower than those in the control group (P < 0.01). After training, the passive angulation errors of 30°, 45° and 60° of the affected knee joints in both groups were significantly lower than those before training (P < 0.01), and those in the observation group were significantly lower than those in the control group (P < 0.05, P < 0.01). After training, the area and length of motion trajectory in both groups with eyes open were significantly smaller than those before training (P < 0.01), and the above indicators in the observation group were significantly smaller than those in the control group (P < 0.05, P < 0.01). After training, the area and length of the movement track of the patients in both groups with eyes closed were significantly smaller than those before training (P < 0.01), and the above indicators in the observation group were significantly smaller than those in the control group (P < 0.01). The satisfaction of patients in the observation group was 95, which was significantly higher than 81% in the control group (P < 0.05). To conclude, compared with the conventional rehabilitation training, the rehabilitation training based on Pro-kin balance system is more effective in improving the function, proprioception and balance function of the affected knee joints of patients undergoing anterior cruciate ligament rupture reconstruction, and the patients’ satisfaction is higher. [ABSTRACT FROM AUTHOR]

目的观察脓毒症患者外周血单个核细胞中 Yes 相关蛋白 (YAP) mRNA 的表达变化, 分析 YAP mRNA 表达与脓毒症预后的关系。方法选择脓毒症患者 49 例纳入脓毒症组, 入院 28d 内存活 28 例､ 死亡 21 例; 选择 健康体检志愿者 38 例纳入对照组。采用 RT-PCR 法检测两组外周血单个核细胞中的 YAP mRNA, 分析脓毒症组 外周血单个核细胞中 YAP mRNA 表达与 APACHEII 评分､降钙素原 (PCT)、乳酸 (Lac) 水平的相关性。采用受试者 工作特征 (ROC) 曲线评估 YAP mRNA 表达, APACHE II评分、PCT、Lac 水平对脓毒症患者预后的诊断效能。结果 脓毒症组及组内死亡者和存活者外周血单个核细胞中 YAP mRNA 表达均高于对照组, 脓毒症组死亡者 YAP mRNA 表达高于存活者 (P均<0.05)。教毒症组死亡者 APACHEII 评分、Lac 水平高于存活者 (P均<0.05)。旅維 菜組 YAP mRNA 表达水平与 APACHE II评分呈正相关(r=0.982, P<0.05) YAP mRNA 预测脓毒症患者死亡的 灵敏度和特异度分别为 0.810.0.929, ROC 曲线下面积为 0.892 (95%CI0.790 -0.994, P<0.05), 预测效能高于 APACHE II评分和 Lac 水平。结论 脓毒症患者外周血单个核细胞中 YAP mRNA 表达升高, 且死亡患者高于存活 患者 YAP mRNA 表达与 APACHE II评分有关。 YAP mRNA 检测有助于预测脓毒症患者的预后。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of National University of Defense Technology / Guofang Keji Daxue Xuebao is the property of NUDT Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of National University of Defense Technology / Guofang Keji Daxue Xuebao is the property of NUDT Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of the Chinese Society of Rare Earths is the property of Editorial Department of Journal of the Chinese Society of Rare Earths and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of the Chinese Society of Rare Earths is the property of Editorial Department of Journal of the Chinese Society of Rare Earths and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To investigate the incidence and characteristics of adverse drug reaction (ADR) in Linyi Pharmaceutical Industrial School (hereinafter referred to as "our hospital"), so as to provide reference for the rational drug use in clinic. METHODS: 909 cases of adverse drug reaction reports reported to National Monitor Center of ADR from Jan. 2011 to Jun. 2013 were statistically analyzed. RESULTS: Of the 909 cases of ADR reports, the ratio of male to female was 1. 04∶ 1. 606 cases (66. 67%) were induced by the intravenous route of administration; 336 cases (36. 96%) were induced by the infection medication, of which 296 cases (88. 10%) were induced by antibiotics; skin and its accessories damage accounted for the highest percentage of ADR. 52 cases were severe adverse reactions, of which 18 cases (34. 62%) were induced by antibiotics. CONCLUSIONS: Drugs for infectious diseases, especially antibiotics was a common cause of ADR, the main clinical manifestations were skin rash and pruritus. Rational use of antibiotics should be emphasized in the clinical practice in order to prevent and reduce the occurrence of ADR. [ABSTRACT FROM AUTHOR]

Copyright of Geomatics & Information Science of Wuhan University is the property of Geomatics & Information Science of Wuhan University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)