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Copyright of Chinese Journal of Aesthetic & Plastic Surgery is the property of Chinese Journal of Aesthetic & Plastic Surgery Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Mycosystema is the property of Mycosystema Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To improving the blood compatibility of pure titanium surface，a series of biomimetic polymers containing phosphorylcholine were synthesized and stable bionic coating on the surface of pure titanium was built. The better phosphorylcholine polymer which was more favorable for surface modification of titanium was optimized through a series of experiments，characterization and evaluation. Firstly, the simple free radical polymerization and the reaction of carboxyl and amino were used to synthesize 5 kinds of random copolymers(hereinafter referred to as PMMDA3-Q，PMMDA3-T，PMMDA5-Q，PMMDA5-T, PMMDA7) with different proportions of 2-methacryloyloxyethyl phosphorylcholine(MPC), methacrylic acid (MA) and dopamine (DA) in two steps. The qualitative and quantitative characterization and analysis were characterized by means of FT-IR，1 H NMR, GPC and UV-Vis. The polymers were assembled on titanium surface respectively by self-assembly and the quantity, surface roughness and the ability of inhibit platelet adhesion and activation of the five kinds of polymer on the surface of the titanium were inspected by means of QCM-D and AFM. Results showed that the polymer PMMDA7 is more suitable as the titanium surface modification polymer，and the experimental basis and methods to build the phosphorylcholine bionic multi-functional coating were provided. [ABSTRACT FROM AUTHOR]

Objective To investigate the effects of heat shock protein70 (HSP70) small interfering RNA ( HSP70 siRNA) on the collagen production of the human keloid fibroblasts. Methods Collecting 56 cases of human keloid tissues, isolating the human keloid fibroblasts and culturing them in vitro. The human keloid fibroblasts were divided into the observation group, the negative group and the blank control group. The HSP70 siRNA and the negative siRNA were transfected into the cells of the observation group and the negative group by the liposome, respectively. Moreover, the blank control group was not transfected. At 24 h after the transfection, the mR.NA expression levels of HSP70, collagen I , and collagen HI was detected by the real-time PCR. The protein expression levels of HSP70, collagen I, and collagen HI were detected by Western blotting. The total collagen in the medium was analyzed by the Sircol collagen assay. Results Compared with the negative group and the blank control group, the mRNA and protein expression levels of HSP70, collagen I , and collagen HI decreased in the observation group, as well as the total collagen in the medium (all P <0.05). However, there were no differences between the negative group and the blank control group (all P>0. 05). Conclusion Transfecting the HSP70 siRNA could inhibit the collagen expression in the human keloid fibroblasts. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Harbin Institute of Technology. Social Sciences Edition / Haerbin Gongye Daxue Xuebao. Shehui Kexue Ban is the property of Harbin Institute of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)