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Copyright of Natural Gas & Oil is the property of Editorial Department of Natural Gas & Oil and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the effect and potential mechanism of early exercise intervention on cerebral myelin in cerebral ischemia rats. Methods A total of 18 SD rats were randomly divided into the sham group, the middle cerebral artery occlusion resting group (MCAO-SED) and the middle cerebral artery occlusion exercise group (MCAO-EX), with 6 rats in each group. Except the sham group, the middle cerebral artery occlusion model was prepared by modified Longa line embolization method in other groups. After modeling, rats in the MCAO-EX group were placed on a treadmill for exercise intervention for 28 days. Neurological function was assessed by modified neural function deficit score (mNSS). Infarct volume was detected by MRI scanning (T2), myelin basic protein (MBP) expression was detected by immunofluorescence. Myelin sheath structure was detected by transmission electron microscopy. Western blot assay was used to detect endoplasmic reticulum stress-related protein expression. Apoptosis was detected by TUNEL staining. Results After 28 days of intervention, compared with the MCAO-SED group, the nerve function recovered well in the MCAO-EX group, infarct volume decreased, myelin integrity increased, MBP fluorescence intensity expression increased and MBP expression level increased. The expression levels of ATF6, p-IRE1, p-PERK and cleaved caspase 3 were significantly decreased, and apoptosis was reduced. Conclusion Early exercise can inhibit endoplasmic reticulum stress-induced apoptosis, promote cerebral myelin repair, reduce infarct size and improve nerve function. [ABSTRACT FROM AUTHOR]

Objective：To construct a rabbit model of abdominal aorta atherosclerosis by a modified balloon injury with a high ⁃ cholesterol diet, and evaluate the expression of immune clearance related proteins in early plaques. Methods：A total of 20 New Zealand rabbits were assigned randomly to 3 groups：a sham group, a classical intervention group and a modified intervention group. The high ⁃cholesterol diet and normal diet were given to the intervention groups and the sham group, respectively for one week, after which the model was constructed through the femoral artery. The rabbits in the sham group were given a general diet, anesthetized, skin cut, isolated femoral artery and sutured, but without balloon injury. For the rabbits in the classic intervention group, a balloon was inserted into the abdominal aorta, inflated and unidirectionally pulled 3 times. For the rabbits in the modified intervention group, the balloon was inserted, inflated and a bidirectionally pushed and pulled for 30-40 times. Following the intervention, the two intervention groups received a high⁃cholesterol diet, while the sham group received a normal diet for another 4 weeks. The intravascular ultrasound was performed to examine the abdominal aorta via the femoral artery, and the injured segments of abdominal aorta were sampled for further hematoxylin ⁃ eosin (HE) and immunohistochemistry staining at the end of the study. Results：There was no significant difference in weight gain measured at 4 weeks post intervention among the 3 groups. The intravascular ultrasound demonstrated significant plaque hyperplasia and lumen stenosis in the modified intervention group. HE staining revealed varying degrees of intimal hyperplasia in all samples from both intervention groups. Compared with the classical intervention group, the modified intervention group exhibited significantly increased in maximum intimal thickness [(174.69±53.76) μm vs. (481.50±81.94) μm, P < 0.05］and mean intimal thickness [(77.49±18.02) μm vs (. 262.63±53.04) μm, P < 0.05］, a higher intimal /media area ratio［0.39±0.14 vs. 1.57± 0.30, P < 0.05］and severer vascular stenosis [(19.04±5.90) % vs. (52.13±11.31) %, P < 0.05] The immunohistochemistry staining revealed significantly enhanced macrophage infiltration in the modified intervention group, compared with the classical intervention group. Moreover, a higher expression of the anti ⁃ phagocytic protein CD47 in the proliferative intima was detected in the modified intervention group than the sham group and the classical intervention group. Conclusion： The novel rabbit model of abdominal aorta atherosclerosis was established by the modified balloon injury and the high ⁃ cholesterol diet, further accelerating early plaque development with an enhanced stability and reliability. A significant necrotic cell clearance impairment was detected in early plaque in this novel model. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Shanghai Jiao Tong University (1006-2467) is the property of Journal of Shanghai Jiao Tong University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

About 30%-40% psychiatric patients respond poorly to multimodal comprehensive treatment including drugs, psychotherapy and other treatment methods, and will further progress to refractory psychiatric patient. Neuromodulation technology has been used in the treatment of refractory psychiatric diseases for more than 60 years. More and more neuroimaging studies have found that the pathophysiology of mental disorders is related to the dysfunction of neural circuits. The anterior limb of the internal capsule (ALIC) is a key point in the neural circuit. Regulation ALIC is becoming more and more important in the treatment of refractory obsessive-compulsive disorder (OCD), severe depression, and other mental diseases. This paper reviews the anatomy, neuroimaging and application progress of ALIC in refractory mental diseases. [ABSTRACT FROM AUTHOR]

In vitro screening of functional nucleic acids (FNAs) by SELEX is an essential prerequisite for their various functions. In the SELEX process, the preparation of high-quality single-strand secondary library is one of the most basic and critical technologies, which largely determines the success or failure of screening. Here, we comprehensively summarize the generation strategies of single-strand DNA for FNAs selection, such as amplification-based methods, enzymatic digestion techniques, magnetic separation with streptavidin-coated beads, and secondary library regeneration strategies based on mobility shift. The advantages, disadvantages and key details of various methods are elaborated with aiming to lay a foundation for the further development of efficient FNAs screening methods. [ABSTRACT FROM AUTHOR]

Copyright of Acta Petrologica et Mineralogica / Yanshi Kuangwuxue Zazhi is the property of Acta Petrologica et Mineralogica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Inorganic Chemicals Industry is the property of Editorial Office of Inorganic Chemicals Industry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Neurosurgery / Linchuang Shenjingwaike Zazhi is the property of Editorial Board of Journal of Clinical Neurosurgery and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Bulletin of the Chinese Ceramic Society is the property of Bulletin of the Chinese Ceramic Society Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Neurosurgery / Linchuang Shenjingwaike Zazhi is the property of Editorial Board of Journal of Clinical Neurosurgery and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Neurosurgery / Linchuang Shenjingwaike Zazhi is the property of Editorial Board of Journal of Clinical Neurosurgery and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Hydrographic Surveying & Charting / Haiyang Cehui is the property of Hydrographic Surveying & Charting Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Coal Science & Technology (0253-2336) is the property of Coal Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)