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急性缺血性卒中再通治疗是一个多因素、多环节作用的复杂临床干预过程。在长期的临床 实践过程中，“时间窗”是一个普遍沿用的概念。早在1996年，3 h内溶栓治疗就已经被证明是急性缺 血性卒中的有效治疗手段，然而获得治疗的患者很少，除了治疗时间窗的限制、未能及时就诊等原因， 单纯的“时间窗”往往提供不了足够的信息以保证溶栓治疗的安全性和有效性。基础血管病变、侧支 循环和缺血耐受的不同，时间窗是否也存在个体差异呢？随着神经影像技术的发展与进步，20多年 来国内外学者一直致力于延长卒中治疗时间窗等方面的研究。 Abstract: Recanalization treatment for acute ischemic stroke is a complicated clinical intervention process, which involves multiple factors and points. Over a long period of time, the concept of “Time Window” is widely used in clinical practice. The efficacy and safety of thrombolytic therapy administered within 3 hours of symptom onset in the treatment of acute ischemic stroke had been proved in 1996. However, beyond the limit of the therapeutic time window and late to medical attention, the safety and validity of recanalization treatment for acute ischemic stroke cannot be ensured by the only “Time Window”. Is there any individual difference in “Time window” based on the different baseline cerebral arterial lesion, collateral circulation and ability of ischemic stroke? With the development and progress of neuroimaging technology, scholars home and abroad have been working on how to extend the therapeutic time window over the past 20 years.

Pheochromocytomas and paragangliomas (extra-adrenal pheochromocytomas) are catecholamine-secreting tumors. The paraganglioma of the urinary bladder is an uncommon neoplasm with a higher malignancy rate. Only about 60% of bladder paragangliomas presented with hematuria, and most of them were microscopic hematuria. Herein, we report two cases of bladder paraganglioma with bladder bloody tamponade. In Case 1, radical cystectomy and regional lymphadenectomy were performed for a huge bladder tumor and left pelvic lymph nodes metastasized. In Case 2, we chose endoscopic transurethral resection of the bladder tumor. Literatures since 1989 were also reviewed to illustrate the clinical characteristics and current treatments.

Rhabdomyosarcoma (RMS) is the most common soft tissue tumor of childhood; about 80% of cases occur before the age of 21 with the remaining 20% evenly spread throughout the remaining decades. A primary paratesticular site is considered to have a good prognosis in comparison with other RMS sites. Histologically, any subtype of RMS, including alveolar, pleomorphic, embryonal, and mixed type, may occur in the paratesticular region, but only a relatively small number of cases are mixed and this variant has a poor prognosis. We report a case of paratesticular RMS (mixed embryonal and alveolar type) in a 16-year-old boy.

BACKGROUND: Osteonecrosis is a common refractory disease in clinical practice, and observational studies have suggested that micronutrients may have a prognostic role in osteonecrosis. However, the specific causal association between micronutrients and osteonecrosis is not known. OBJECTIVE: To explore the causal association between micronutrients and osteonecrosis by Mendelian randomization using summary data from a large population-based genome-wide association study (GWAS) for clinical diagnosis and treatment. METHODS: The required exposure and outcome data (calcium, magnesium, iron, vitamin E, carotenoids, retinol & osteonecrosis) were extracted from the IEU OpenGWAS database, GWAS catalog database, and FinnGen database. Data were analyzed by bidirectional Mendelian randomization with inversevariance weighted as the primary study method, and weighted median method, simple mode method, weighted mode method, and MR-Egger regression to complement the results. The reliability of the data was then verified through sensitivity analyses. RESULTS AND CONCLUSION: (1) The results found a positive correlation between serum iron concentration and osteonecrosis, while no correlation was found for other micronutrients. There was no reverse causality in all the data. (2) The results of sensitivity analysis showed a robust causality. (3) By Mendelian randomization method, this study provided evidence of causality between serum iron concentration and osteonecrosis, and understanding the causality of micronutrient elements on osteonecrosis can help in the clinical diagnosis and treatment of osteonecrosis, which is of great clinical significance. [ABSTRACT FROM AUTHOR]

Copyright of Engineering Mechanics / Gongcheng Lixue is the property of Engineering Mechanics Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Spodoptera frugiperda is a highly destructive pest that can damage crops and pose a serious threat to food security. The S. frugiperda multiple nucleopolyhedrovirus Hubl (SpfrNPV Hubl) represents the pioneering virus specifically targeting S. frugiperda, thereby exhibiting promising prospects for practical applications. This paper aims to assess the impact of various temperature, pH value, and light conditions on the stability of SpfrNPV activity using the residual film method. The stability test results demonstrated that SpfrNPV Hubl exhibited stability at pH 4 and pH 7, as well as at temperatures of 4°C and 25°C. However, it displayed reduced stability at pH 9 and proved to be unstable under conditions of 54°C and 4000 lx illumination. The results of field trials revealed that SpfrNPV Hub1 2 billion PIB(polyhedral inclusion body) /mL SC effectively controlled S. frugiperda. When applied at a dose of 1500-1875 mL/hm², the control efficiency remained consistently high, ranging from 81.18% to 82.57% at 7 days after application and from 81.23% to 83.06% at 14 days after application, indicating long-lasting effect. This study provides valuable insights into the impact of temperature variations, pH levels, and light conditions on the activity of SpfrNPV Hubl while offering essential technical guidance for its application in controlling S. frugiperda. [ABSTRACT FROM AUTHOR]

Copyright of Forensic Science & Technology is the property of Institute of Forensic Science, Ministry of Public Security and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Research of Soil & Water Conservation is the property of Institute of Soil & Water Conservation, Chinese Academy of Sciences & Ministry of Water Resources and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Refractories / Naihuo Cailiao is the property of Naihuo Cailia (Refractories) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Electric Power Automation Equipment / Dianli Zidonghua Shebei is the property of Electric Power Automation Equipment Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Exploring the evolution of water quality purification triggered by land use change is important for protecting and improving water quality and achieving sustainable development. Taking the “ Two Lakes and One Reservoir” basin as an example, the patch-level land use simulation ( PLUS ) model and the integrated valuation of ecosystem services and tradeoffs ( InVEST ) model ecosystem service water quality purification module were used to simulate changes in the spatial and temporal patterns of land use types as well as the characteristics of water quality purification of the basin under future natural development scenarios and ecological protection scenarios based on the land-use data for the years 2000, 2010 and 2020. The response relationship was quantitatively reveal between land use change and water purification function. The results show that the land type of the “ Two Lakes and One Reservoir” basin is dominated by arable land, and in 2030, the area of arable land, forest land and grassland under the natural development scenario shows a decreasing trend, and the area of construction land shows an increasing trend, and the ecological protection scenario can effectively protect the spatial distribution and area of the basin’ s arable land and forest land, etc. The TN and TP outputs of the “ Two Lakes and One Reservoir” basin are dominated by the low-intensity outputs, and the outputs of TN increase firstly and then decrease, and TP outputs increase year by year during the period of 2000—2020. From 2000 to 2020, TN output first increases and then decreases, TP output increases year by year, and the water purification capacity shows a steady trend. In 2030, TN output continues to decrease under the natural development scenario, and TP output shows an upward fluctuation, and TN and TP output under the eco-protection scenario is reduced compares with that under the natural development scenario, and the eco-protection scenario can increase the water purification capacity. Ecological land types can effectively intercept N and P into the water body, and the ecological protection scenario effectively reduces the rate of change of ecological land types and reduces the output of TN and TP. The future planning of the “ Two Lakes and One Reservoir” basin should increase the proportion of ecological land, and increase the ability of land types to intercept TN and TP. [ABSTRACT FROM AUTHOR]

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Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Using silica aerogels as the matrix material and low-temperature phase change paraffin wax as the phase change material, shaped composite phase change materials were prepared. Characterization and stability tests of the shaped composite phase change materials were conducted using Fourier-transform infrared spectroscopy, differential scanning calorimetry, synchronous thermal analysis, and diffusion-permeation circle tests. The results indicate that the shaped composite phase change material prepared with a wax adsorption mass of 75% is the most stable, with the interaction between silica aerogels and paraffin wax being purely physical adsorption. The phase transition temperature of the shaped composite phase change material is 26.52 °C, and the latent heat of phase transition is 56.2 J/g» By incorporating it into EPS concrete, the cement paste flowability experiment restricts the optimum proportion of shaped composite phase change material to around 16%, yielding optimal working performance of the concrete mixture. Physical-mechanical property tests reveal that with the addition of the shaped composite phase change material, the compressive, flexural, and splitting tensile strengths of the specimens all exhibit a certain degree of improvement. Through thermal storage performance tests in a thermal chamber, specimens with added shaped composite phase change material show a decrease in the slope and peak value of the heating and cooling curves. This indicates that lightweight phase change concrete has excellent temperature control performance and can be used in energy-efficient building envelope systems. [ABSTRACT FROM AUTHOR]

Shaoyang being in charge of bone theory is originally from the Huangdi Neijing. After the continuous deepening and improvement of many generations of doctors in the past, it has now become a comprehensive theoretical system of traditional Chinese medicine for orthopedic diseases. Osteoporosis is a systemic chronic bone metabolic disease. Its main form is the loss of bone mass in the whole body and the destruction of bone microstructure. This characteristic corresponds to flaccidity of bones, bone bi-disease, and other traditional Chinese bone diseases. However, modern doctors rarely treat such diseases from the perspective of Shaoyang. In this paper, the essence of Shaoyang being in charge of bone and the connection between Shaoyang and OP are clearly sorted out. The method of treating OP from the perspective of Shaoyang is discussed. This has practical significance of the theory of Shaoyang being in charge of bone and has extremely great value for guiding the TCM prevention and treatment program of OP patients. [ABSTRACT FROM AUTHOR]

Highly dispersed nano calcium carbonate was prepared using limestone as raw material by low-temperature carbonization method. The nano calcium carbonate samples were characterized by XRD, SEM, TEM, etc. The effects of slurry ratio, carbonization temperature, CO2 aeration rate, aging time, and crystal control agent on the particle size and dispersion degree of nano calcium carbonate were investigated. The process conditions for preparing nano calcium carbonate were obtained as follows: slurry ratio of 5%, carbonization temperature of 15 ℃, CO2 aeration rate of 200 mL/min, aging time of 2 h, and ZnCl2 as the crystal control agent. Under these conditions, cubic nano calcium carbonate with a grain size of 25 ~35 nm and uniform distribution was prepared. The growth mechanism of nano calcium carbonate was analyzed by Materials Studio. The results show that the (104) and (116) crystal planes of calcium carbonate were thermodynamically stable and would eventually become tenacious exposed crystal planes, which promots the generation of cubic nano calcium carbonate. [ABSTRACT FROM AUTHOR]

Copyright of New Building Materials / Xinxing Jianzhu Cailiao is the property of New Building Materials Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)