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Copyright of Mechanical & Electronic Control Engineering is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The food additive titanium dioxide is commonly utilized to enhance the appearance and flavor of food products. However, this substance has been linked to gastrointestinal disorders. The aim of this study was to investigate the impact of dietary exposure of titanium dioxide E171 on Listeria monocytogenes infection in mice. Mice were mainly divided into the control, LM group (L. monocytogenes infection), and E171+LM groups (E171 supplementation before L. monocytogenes infection). Pre-exposure to E171 resulted in increased bacterial counts in the liver, spleen, ileum, colon, mesenteric lymph nodes, and feces of mice after L. monocytogenes infection. Moreover, E171 exposure increased the levels of pro-inflammatory cytokines while attenuating the levels of anti-inflammatory cytokines in mice infected with L. monocytogenes. Meanwhile, mice in the E171+LM group exhibited considerably more severe colonic inflammation and worse intestinal barrier function than mice in the LM group. The 16S rRNA gene sequencing revealed a shift in the composition of the gut microbiota of mice in the E171+LM group, characterized by a decrease in the relative abundance of Firmicutes and a decrease in the Firmicutes-to-Bacteroidetes ratio. The levels of acetate, butyrate, and isobutyrate were markedly decreased within the cecum of mice in the E171+LM group in comparison to mice in the LM group. In conclusion, these results suggest that E171 exposure could exacerbate L. monocytogenes infection in mice, which may provide useful information for future risk assessment of this commonly used food additive. [ABSTRACT FROM AUTHOR]

Copyright of Storage & Process is the property of Tianjin Academy of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the clinical value of serum progranulin (PGRN) in non-traumatic osteonecrosis of femoral head (NONFH). Methods A total of 75 patients with NONFH were selected as the NONFH group, and 67 healthy individuals matched for sex and age were selected as the healthy group. Serum PGRN concentration was detected by enzymelinked immunosorbent assay. The visual analogue scale (VAS) and Harris score were used to evaluate the hip joint pain and function. The general data and imaging results were compared between the two groups. The serum PGRN levels of NONFH patients with different clinical characteristics were compared. The correlation between PGRN and clinical indicators was analyzed. Receiver operating characteristic (ROC) curve was used to analyze the diagnostic value of serum PGRN level in NONFH. Results The level of serum PGRN was significantly higher in the NONFH group than that in the healthy group (P＜0.05). There was no significant difference in PGRN levels between NONFH patients with different etiologies. The level of PGRN was significantly higher in NONFH patients with bilateral necrosis than that in patients with unilateral necrosis, and the level of PGRN was significantly higher in NONFH patients with femoral head collapse than that in patients without collapse (P＜0.05). The level of serum PGRN was positively correlated with ARCO stage (rs=0.645) and VAS score of pain (r=0.694), but negatively correlated with Harris score (r=-0.732, P＜0.01). ROC curve results showed that the area under the curve of PGRN for the diagnosis of NONFH was 0.786 (95%CI: 0.710-0.862, P＜0.01), the optimal cut-off value was 14.55 µg/L, the sensitivity was 0.640 and the specificity was 0.910. Conclusion Serum PGRN level can reflect the severity of NONFH and has certain value in the diagnosis of NONFH. [ABSTRACT FROM AUTHOR]

髋关节发育不良（DDH）是成人髋关节骨关节炎的最常见原因之一，临界性髋关节发育不良（BDH）是介 于正常骨盆与典型髋关节发育不良骨盆的一种“过渡性”的髋臼覆盖状态。DDH的诊断主要依靠外侧中心边缘角 （LCEA），BDH通常被定义为LCEA在20°~25°。当LCEA<20°时，临床上一般应用髋臼周围截骨术（PAO）治疗，而临 界性髋关节发育不良的最佳治疗方法（PAO或关节镜手术）尚无统一定论 [ABSTRACT FROM AUTHOR]

Copyright of Experimental Technology & Management is the property of Experimental Technology & Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Geomatics & Information Science of Wuhan University is the property of Geomatics & Information Science of Wuhan University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)