Search

为了寻找一种更好的FBG（光纤布拉格光栅）中心波长检测的寻峰算法,采用LabVIEW技术和MATLAB技术完成了FBG解调系统中9种寻峰算法的编写和调试,并对各种算法的参数及其优劣进行了分析比较。通过对仿真信号及实测FBG信号的误差分析,结合实验研究和算法仿真,给出了算法误差及相关影响因素。结果表明,最佳寻峰算法为高斯拟合法。

Copyright of Resources Development & Market is the property of Sichuan Resource Development & Market Magazine Co., Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Control Theory & Applications / Kongzhi Lilun Yu Yinyong is the property of Editorial Department of Control Theory & Applications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Food Science & Technology is the property of Editorial Office of Modern Food Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Materials Science & Engineering (1673-2812) is the property of Journal of Materials Science & Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective　To establish a prediction model for lymph node metastasis and recurrence of thyroid cancer by analyzing patients’ lymph node FNA-Tg values, serum Tg values, and their ratios by binary logit regression. Methods　1. 64 patients with preoperative differentiated thyroid cancer with suspected lymph node metastasis were collected. 2. The diagnostic value of FNA-Tg value, serum Tg value, and their ratios for the differentiation of benign and malignant lymph nodes were initially evaluated by the ROC curve. 3. The diagnostic value of the above three indices was further evaluated by binary logit regression analysis and a prediction model was established. Results　1. ROC curve：the AUC value corresponding to lymph node FNA-Tg was 0.998 (95% CI 99.27%-100.34%), with a cut point value of 0.82; the AUC value corresponding to serum Tg was 0.824 (95% CI 70.64%-94.14%), with a cut point value of 18.27; the AUC value corresponding to lymph node FNA-Tg/serum Tg The AUC value of FNA-Tg/serum Tg in lymph nodes was 1.000 (95% CI 100.00%-100.00%), and the cut point value was 0.461. 2. Binary logit regression all-entry method with the simultaneous presence of three independent variables：i) Binary logit regression all-entry method with the simultaneous presence of three independent variables： FNA-Tg value, serum Tg value and their ratios all had P values > 0.05, and the model The simultaneous presence of three independent variables has no diagnostic value for benign and malignant lymph nodes; ii) Binary Logit regression all-entry method lymph node FNA-Tg single variable results：lymph node FNA-Tg could explain 88% of the variation in benign and malignant lymph nodes, P = 0.038 < 0.05, regression coefficient 2.68, OR value 14.587, prediction model formula was：In (p/1-p) = -4.122 + 2.680* lymph node FNA-Tg, likelihood ratio test P = 0.000 < 0.001, AIC value 14.386, BIC value 18.704, overall prediction accuracy of 95.31%; iii) Binary Logit regression all-entry method serum Tg single variable results：serum Tg explained 27.8% of the variation in benign and malignant lymph nodes, P = 0.000 < 0.001, regression coefficient 0.164, OR 1.179, prediction model formula: In (p/1-p) = -2.466 + 0.164*serum Tg, likelihood ratio test P = 0.000 < 0.001, AIC value 67.33, BIC value 71.648, overall prediction accuracy 75%. Conclusions　1. Preoperative FNA-Tg, serum Tg and their ratios have good diagnostic value in determining the benignity and malignancy of thyroid nodules. 2. The binary logit regression model (stepwise method) formula based on serum Tg can better predict the benignity and malignancy of thyroid nodules. [ABSTRACT FROM AUTHOR]

本文推导出切比雪夫迭代应用于多项式求根的迭代形式，阐述了优函数的一些性质以及优序列的收敛性，给出了切比雪夫迭代应用于多项式求根的变形形式并证明了收敛性定理.

Objective　To explore the diagnostic significance of FNA-Tg for lymph nodes with suspected cervical thyroid papillary carcinoma metastasis on the basis of ultrasonic detection and guidance and accurate biopsy of FNA，and establish the threshold of FNA-TG. Methods　74 lymph nodes with suspected metastasis of thyroid cancer were evaluated by fine needle aspiration and analysed pathologically. Lymph nodes were evaluated by comparing FNA alone，FNA-TG value with serum Tg，and drawing ROC to obtain the best diagnostic value of FNATG， and the sensitivity， specificity and accuracy of positive results were evaluated. Results　There were significant differences in calcification，cortex-medullary boundary，abnormal blood supply and aspect ratio in the diagnosis of cervical lymph node metastasis of papillary thyroid carcinoma （P < 0.05）. The above four indexes had the highest sensitivity in the diagnosis of lymph node metastasis of thyroid cancer. Calcification，multiple hyperecho，cystic changes and elastic imaging had higher hardness specificity，and the accuracy of cortex-medulla boundary and aspect ratio was the highest. The sensitivity，specificity and accuracy of FNA were 75%，100% and 87.84%. The sensitivity，specificity and accuracy of FNA-Tg/ serum Tg value > 1 were 97.22%，100% and 98.65%. ROC curve was drawn to obtain the optimal diagnostic threshold of FNA-Tg as 0.575 ng/mL. Conclusion　FNA-Tg/ serum Tg > 1，as the diagnostic criteria for lymph node metastasis of papillary thyroid cancer，can better avoid the disadvantages caused by many factors and effectively reduce the error rate，and should be the first choice for the auxiliary diagnosis of lymph node metastasis of papillary thyroid cancer. [ABSTRACT FROM AUTHOR]

Copyright of Journal of International Reproductive Health/Family Planning is the property of Editorial Board of the Journal of International Reproductive Health/Family Planning and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Plastics Science & Technology / Suliao Ke-Ji is the property of Plastics Science & Technology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hydrobiology / Shuisheng Shengwu Xuebao is the property of Editorial Department of Journal of Hydrobiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the clinical features and gene mutations of a pedigree with Charcot-Marie-Tooth disease（CMT）. Methods A patient with CMT was selected. The clinical characteristics of the patient were analyzed retrospectively and his first-degree relatives were investigated. The mutant genes of the family members were analyzed by multiple ligation-dependent probe amplification technique, and then were verified by first-generation DNA sequencing. Results The patient was in his youth at the onset of CMT. The clinical manifestations were characterized by slow progressive muscle weakness of the distal extremities with muscle atrophy and decrease or disappearance of tendon reflex. The detection of biochemical indexes of cerebrospinal fluid showed that the white blood cell count and total protein increased, and electromyography showed that the sensory and motor conduction velocities of the upper and lower extremities slowed down or could not induce response waves. The family with a total of two generations of four people were permanent residents in Shandong province, Han nationality, and only one case was CMT patient. The disease gene mutation analysis showed that the patient had a GJB1 gene c. 44 G→A（Arg15Gln）hemizygote mutation and a new PRX gene c. 3208 C→G （Arg1070Gly）heterozygous variation. The sister of the patient had both heterozygous mutation of GJB1 gene c. 44 G→A （Arg15Gln）and heterozygous variation of PRX gene c. 3208 C→G（Arg1070Gly）. The mother of the patient had a heterozygous mutation of GJB1 gene c. 44 G→A（Arg15Gln）. The father of the proband had a heterozygous variation of PRX gene c. 3208 C→G（Arg1070Gly）. Conclusions The clinical features of this patient with CMT are slowly progressive distal muscle weakness with muscle atrophy and decrease or disappearance of tendon reflex. The white blood cell count and total protein level increase slightly in the cerebrospinal fluid examination, and the sensory and motor conduction velocity of limbs decrease or could not induce waves by electromyography. Mutation gene analysis shows that there are both GJB1 gene c. 44 G→A hemizygote mutation and PRX gene c. 3208 C→G heterozygote variation. The GJB1 gene c. 44 G→A mutation is the pathogenic mutation of the family. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hydrobiology / Shuisheng Shengwu Xuebao is the property of Editorial Department of Journal of Hydrobiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

At present, most methods need to process face alignment in advance, which not only verifies the continuity of the process, but also seriously affects the efficiency of face verification. In order to solve the above problems, this paper proposes a framework of unaligned face verification based on deep learning. In the process of face verification, SIFT descriptors of face feature is generated synchronously by making full use of the pooling results of deep learning, and these SIFT descriptors are used to cascade verify the unaligned face from coarse granularity to fine granularity, which will greatly improve the speed and accuracy of face verification. In the training stage, utilizing three-tuple samples as input, Triplet loss as loss function to improve the accuracy of face verification. In this paper, according to different application scenarios, two kinds of CNN are designed to meet the needs of smartphone and large devices. After a long time training on WEB-face dataset and experimenting on the LFW, YOUTUBE datasets, the results show that the proposed method has the superior performance compared with some state-of-the art methods． [ABSTRACT FROM AUTHOR]

Functional hypothalamic amenorrhea (FHA) is characterized by the low levels of serum gonadotropin and estrogen in young women, in which the organic lesion of hypothalamus and hypophysis has been excluded. FHA has negative effects on the cardiovascular system, skeletal system, reproductive system and mental health of patients. Many factors may induce FHA, such as excessive exercise, nutritional deficiencies, dieting, and mental stress, or the combination of those factors. The treatment of FHA should be comprehensive, including the increased weight, the reduced strenuous -exercise, gonadotropin releasing hormone pulse therapy, hormone replacement therapy and cognitive behavioral therapy. The research progress of functional hypothalamic amenorrhea is reviewed. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Oncology is the property of Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Tourism Tribune / Lvyou Xuekan is the property of Tourism Institute of Beijing Union University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To analyze the quality of Chuanxiong rhizoma formula granules from different manufacturers. METHODS: According to the requirements of the Pharmacopoeia of the People’s Republic of China(2015 edition), the moisture, particle size, solvency, drug induced moisture, loading, extraction, content and fingerprints were measured on the particles of 6 manufacturers and the quality was examined. RESULTS: The moisture content, particle size, loading, and solvency of the 6 manufacturers were all in compliance with the regulations, yet the gaps between the extraction, contents and fingerprints of different manufacturers’ samples were larger. CONCLUSIONS: The quality of Chuanxiong rhizoma formula granules produced by different manufacturers is quite different, which need to be attached more importance in clinic. [ABSTRACT FROM AUTHOR]

Objective To optimically prepare for biotin-microbubbles with small diameter and good stability, and evaluate the physical and chemical properties, and the effect of contrast. Methods We prepare lipid vesicles with different proportion for the group A-E. The physical and chemical properties of each group were evaluated by particle size analyzer and Malvern. We evaluated the effect of different solvents on the stability of the group1-3, observed the effect of each group by ultrasonic diagnostic apparatus. Results There were significant differences between groups A, C and E:Lipid located the different layers of the vial； With the increasing of DPPC, MPEG200, DPPA, the average size and concentration decreased gradually, the distribution became uniform gradually, and the Zeta decreased gradually. Complex solution made microbubbles with small size, non-rupture, concentration maintain and good stability. Conclusions DPPC：MPEG200：DPPA：DSPE-PEG2000-Biotin 90:5:5:10 and complex solution can make the best biotin-microbubbles. It is a optimal choice for preparation of target microbubbles. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Shanghai Physical Education Institute / Shanghai Tiyu Xueyuan Xuebao is the property of Shanghai Physical Education Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To determine the difference of serum level of osteoprotegerin( OPG) between Uyghur and Han elder people in Xinjiang,and to explore the correlation between serum OPG and bone mineral density-T( BMD-T) of the lumbar vertebrae and the left proximal femur. Methods Three hundred and twelve elder people( over 60 years old) in the First Affiliated Hospital of Xinjiang Medical University from October 2011 to December 2013 were selected. BMD of the lumbar vertebrae and the left proximal femur was detected using dual energy X-ray absorptiometry( DXA). Serum level of OPG was detected using ELISA method. Results( 1) The serum level of OPG in abnormal bone mass group 1. 588( 1. 559) was lower than that in the normal bone mass group 2. 062( 1. 606)( Z = 1. 531,P = 0. 018).( 2) The serum level of OPG in Uyghur group 1. 503( 1. 033) was lower than that in the Han group 1. 971( 1. 805)( Z = 1. 834,P = 0. 002). When stratified by gender,the serum level of OPG in Uyghur males 1. 474( 0. 729) was lower than that in Han males 2. 062( 1. 712)( Z = 2. 215,P = 0. 000). There was no significant difference in women between the two people( P > 0. 05). By case control stratification,the serum level of OPG in Uyghur population 1. 772( 1. 044) of normal bone mass was lower than that in Han with normal bone mass 2. 303( 2. 031)( Z = 1. 404,P= 0. 039),while there was no significant difference in lowbone mass group between the two ethnics( P > 0. 05).( 3) Spearman partial correlation analysis showed that the serum level of OPG was negatively correlated with BMD-T of L2,L3,L4,L total,Neck,G. T,Inter Tro,and the hip location in female Han( r =- 0. 333- 0. 235,P = 0. 02- 0. 032). The serum level of OPG was positively correlated with BMD-T of G. T( r = 0. 174,P = 0. 026) in male Han. There was no correlation between OPG and BMDT of any location in Uyghur people. After control of age and BMI,the serum level of OPG was still positively correlated with T value of L2,L3,L total,Inter Tro,and the hip in female Han.( 4) Binary linear regression showed that serum OPG was a negative determinant of L1-T,L2-T,L3,L total-T,and Inter Tro-T,which could explain the 0. 8%- 10% variation of the T value.( 5)Fitting curve showed that OPG and BMD-T of L1,L2,L3,L total,and Inter Tro was linearly fit in Han females. Best quadratic polynomial fit was found between serum level of OPG and T value of GT and Hip. There was no fit between serum level of OPG and L4-T and Neck T. Conclusion The serum level of OPG in Uyghur elderly is lower than that in Han population,and especially it is lower in Uygur men. The serum level of OPG could be an influence factor to the variation of BMD-T value in Han female elderly. [ABSTRACT FROM AUTHOR]

Objective To investigate the clinical value of ultrasonic tissue dispersion quantitative analysis in the assessment of chronic hepatitis B liver fibrosis， in order to provide a method to assess liver disease and early prevention. Methods 47 patients with chronic hepatitis B infection were choose from the First Affiliated Hospital of Kunming Medical University branch in October 2014 - February 2014 as experimental research objects. Using the liver biopsy and according to the pathological staging of liver fibrosis standard，the patients were divided into five periods （S0 - S4） . The other selected 10 cases of healthy people as control group. All research objects underwent routine line of conventional ultrasound and inspection organization dispersion quantitative analysis，and calculation of liver fibrosis index （LFI） . Using single factor variance analysis and comparison of liver fibrosis stage between groups of LFI values of statistical significance，combined with the pathological results using Spearman correlation analysis，and comparing two further the LSD - t test and SNK test to calculate LFI the accuracy of the diagnosis of liver fibrosis，ultrasonic quantitative indicators at dispersion degrees and draw the receiver-operating characteristic curve （ROC） . Results The pathological staging differences were statistically significant （ < 0.001）, suggested the different staging of 5 groups patients with liver disease had different dispersion degree or not completely the same. Pairwise comparison of LSD - t test， SNK test， the differences between groups were statistically significant. The AUC area under the curve （AUC） of the 5 groups were 0.896， 0.909， 0.918， 0.963，and 0.950， respectively. Conclusion （1） LF RTE index and degree of liver fibrosis were positively correlated，and the LF reference level thresholds were S0 1.78 0.35，S1 2.24 0.45，S2 2.77 0.29， S3 3.25 0.59，and S4 3.80 0.21； （2） The RTE was in conformity with the pathological staging of liver fibrosis， which can be used to evaluate the degree of liver fibrosis in clinical， avoid or reduce the liver biopsy， and was more suitable for follow-up. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Southern Agriculture is the property of Journal of Southern Agriculture and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 通过联合应用颅脑常规MRI、高分辨磁共振血管壁成像3D CUBE T1序列及SWI对颅内静脉窦 及其内血栓的显像，评价3D CUBE T1序列和SWI对颅内静脉窦血栓（cerebral venous sinus thrombosis， CVST）的诊断效能及应用价值。 方法 本研究为前瞻性研究，连续纳入山东第一医科大学第一附属医院神经内科2016年3月-2017 年9月临床疑诊CVST的34例患者。行颅脑MRI平扫、MRV、SWI、3D CUBE T1序列检查。将颅脑平扫与 MRV的诊断结果作为确诊CVST的参照诊断，应用ROC曲线分析评估3D CUBE T1序列及SWI在患者及静 脉窦血管节段水平诊断CVST的敏感性、特异性。 结果 以参照诊断为依据评判CVST的阳性患者共9例，共累计24处病变静脉窦节段。3D CUBE T1序 列在患者水平诊断CVST的敏感度和特异度分别为100%和95.2%，ROC曲线下面积为0.98；在静脉窦 节段水平诊断CVST的敏感度和特异度分别为95.8%和97.7%，ROC曲线下面积为0.97。SWI在患者水平 诊断CVST的敏感度和特异度分别为66.7%和76.2%，ROC曲线下面积为0.71；在静脉窦节段水平诊断 CVST的敏感度和特异度分别为70.8%和95.4%，ROC曲线下面积为0.83。 结论 与SWI相比，高分辨磁共振血管壁成像3D CUBE T1序列对CVST的诊断具有更高的敏感性及 特异性，准确性高，能够为CVST的临床诊断及治疗提供可靠的诊断信息，具有很好的临床实用价值及 应用前景。 Abstract: Objective To evaluate the diagnosis value of HR MR vessel wall imaging 3D CUBE T1 sequence and SWI for cerebral venous sinus thrombosis (CVST). Methods This was a prospective study. 34 consecutive suspected CVST patients from Department of Neurology, the First Affiliated Hospital of Shandong First Medical University from March 2016 to September 2017 were included in this study. All the patients underwent MRI plain scan, MRV, SWI and 3D CUBE T1 sequence imaging examination. The diagnostic accuracy for CVST of 3D CUBE T1 and SWI on per patient and per venous sinus segment level were evaluated by calculating their sensitivity, specificity, and the area under the ROC curve (AUC), with referential diagnostic criteria of CVST diagnosis based on the combination of MRI plain scan and MRV. Results Finally, a total of 9 CVST patients were diagnosed according to the referential criteria,including 24 venous sinus stenosis segments. For 3D CUBE T1 sequence, the sensitivity and specificity of were 100% and 95.2% per patient, and were 95.8% and 97.7% per venous sinus segment, and AUC was 0.98 per patient and 0.97 per venous sinus segment, respectively. For SWI, the sensitivity and specificity were 66.7% and 76.2% per patient, and were 70.8% and 95.4% per venous sinus segment, and AUC was 0.71 per patient and 0.83 per venous sinus segment, respectively. Conclusions Compared with SWI, HR MRI 3D CUBE T1 sequence has a higher sensitivity and specificity in diagnosing CVST, which can provide reliable information for diagnosis and treatment of CVST.