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Copyright of Journal of Shanghai University of Sport is the property of Editorial Department of Journal of Shanghai University of Sport and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Bacillus velezensis is an important representative of biocontrol strains in the genus Bacillus. It is widely used as the core strain of biological pesticide in the biocontrol of plant diseases. B. velezensis has endophytic properties in plants, and its biocontrol mechanism mainly includes three aspects. Firstly, it can produce the secondary metabolites against pathogens. Secondly, it can improve host plant microbial community to promote host nutrition and growth. The last, it can stimulate the plant to produce a defense response and develop systemic resistance. Among them, the production of secondary metabolites is the most important mechanism of biocontrol. B. velezensis contains multiple biosynthesis gene clusters encoding secondary metabolites, including gene clusters encoding polyketide synthase(PKS)and non‑ribosomal peptide synthase(NRPS), as well as gene clusters for ribosomal pathway synthesis of secondary metabolites. B. velezensis can produce plantazolicin, amylocyclicin, and mersacidin through the ribosomal pathway, and produce lipopeptides, polyketides, bacilysin, and bacillibactin through non‑ribosomal pathways. These bioactive secondary metabolites have become repositories of natural new drugs and candidate antibiotics, which is of great significance for analyzing the mechanism of biocontrol action. This paper reviews the naming and alteration, the types of secondary metabolites, synthesis and regulation genes, and target pathogens of B. velezensis. It aims to provide a scientific basis for new theories and applications of strain improvement and plant disease biological control. [ABSTRACT FROM AUTHOR]

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Guangdong Architecture Civil Engineering is the property of Guangdong Architecture Civil Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Synthetic Crystals is the property of Journal of Synthetic Crystals Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Guangdong Architecture Civil Engineering is the property of Guangdong Architecture Civil Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Frontiers of Computer Science & Technology is the property of Beijing Journal of Computer Engineering & Applications Journal Co Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shanghai Physical Education Institute / Shanghai Tiyu Xueyuan Xuebao is the property of Shanghai Physical Education Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shanghai Physical Education Institute / Shanghai Tiyu Xueyuan Xuebao is the property of Shanghai Physical Education Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shanghai Physical Education Institute / Shanghai Tiyu Xueyuan Xuebao is the property of Shanghai Physical Education Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the protective effect of recombinant adeno-associated virus (rAAV) mediated nerve growth factor (NGF) transfection by intramyocardial injection or subarachnoid injection in type 1 diabetic rats. Methods The whole experiment consists of two sub-experiments, experiment A:12 SPF grade male SD rats were randomly divided into control group (group control) and diabetes mellitus group (group DM, n=6). Group DM was given streptozotocin (STZ, 50 mg/kg, i.p) to induce type 1 diabetic rat model. The tail flick latencies were measured one day before STZ injection and 1, 2, 4, 6, 8 and 9 weeks after STZ injection in two groups of rats. The contents of NGF and calcitonin gene-related peptide (CGRP) were measured by ELISA method. Experiment B:24 SPF grade male SD rats were randomly divided into 4 group (n=6): diabetic heart transfection control group (group MC), diabetic heart transfection group (group ME), diabetic spinal cord transfection control group (group SC) and diabetic spinal cord transfection group (group SE). The 2×2 factorial design was used in this study. The diabetic rat model was established by giving STZ (50 mg/kg, i.p) in four groups of rats. At the end of 4 weeks after injection of STZ, rats in group MC and ME were transfected with rAAV-green florescent protein (GFP) and rAAV-NGF-GFP at a titer of 0.8×1013 virus genomes (μg/L) by intramyocardial injection at 100 μL. Rats in group SC and SE were transfected with rAAV-GFP and rAAV-NGF-GFP at a titer of 0.8 × 1012 virus genomes (μg / L) by subarachnoid injection at 25 μL. After 5 weeks, the cardiac function indexes were measured in groups of rats. The expressions of GFP in myocardium, spinal cord and dorsal root ganglion of T1-T5 were observed by fluorescence microscope, and the contents of NGF and CGRP were measured by ELISA method. Results In experiment A, after 4 weeks, the tail flick latency was significantly delayed in group DM compared with that of group control (P＜0.05). The NGF and CGRP protein in myocardium were significantly decreased in group DM compared with those of group control (P＜0.05). In experiment B, both rAAV-NGF-GFP and myocardial tissue as transfection pathway significantly improved the cardiac function of rats (P＜0.05), and up-regulated the contents of NGF and CGRP protein in myocardial tissue (P＜0.05). There was an interaction between transfectants and transfection pathways during the experiment. Combination of both can improve cardiac function and up-regulate NGF and CGRP in myocardium (P＜0.05). The myocardial point injection of rAAV-NGFGFP can significantly improve the cardiac function of rats (P＜0.01), and up-regulate the contents of NGF and CGRP protein in myocardial tissue (P＜0.01). Conclusion Compared with subarachnoid injection, intramyocardial injection of rAAV-NGF can effectively increase the expression of NGF in myocardial tissue of diabetic rats and have a more effective cardioprotective effect. eng [ABSTRACT FROM AUTHOR]

Copyright of Journal of Shanghai Physical Education Institute / Shanghai Tiyu Xueyuan Xuebao is the property of Shanghai Physical Education Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shanghai Physical Education Institute / Shanghai Tiyu Xueyuan Xuebao is the property of Shanghai Physical Education Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Capital Institute of Physical Education is the property of Shoudu Tiyu Xueyuan and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shanghai Physical Education Institute / Shanghai Tiyu Xueyuan Xuebao is the property of Shanghai Physical Education Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Physical Education / Tiyu Xuekan is the property of Journal of Physical Education Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Physical Education / Tiyu Xuekan is the property of Journal of Physical Education Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Physical Education / Tiyu Xuekan is the property of Journal of Physical Education Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Physical Education / Tiyu Xuekan is the property of Journal of Physical Education Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)