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Objective To explore the feasibility and effectiveness of an online service offering Traditional Chinese Medicine (TCM) physique conditioning under the normalization of epidemic prevention and control. Methods From March 1, 2020 to March 10, 2020, 190 subjects who were judged as "Qi deficiency" by "TCM constitution test" were recruited online. A research team was set up to develop physique conditioning plans, formulate "Ear Massage", construct a physique conditioning WeChat group and public account for Qi-deficiency subjects, and provided online physique conditioning services for 6 months. The conversion score of Qi-deficiency, the frequency of respiratory infection in 6 months and psychological status were compared before and after intervention. Results Compared with before intervention, the conversion score of Qi-deficiency, the frequency of respiratory infection in 6 months, the negative emotion score and total score of the five dimensions of depression, nervous decline, fear, compulsion-anxiety and hypochondria of the subjects decreased, with statistical significance(P

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Copyright of Feed Industry is the property of Liaoning Provincial Institute of Agricultural Mechanization and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Study on Optical Communications / Guangtongxin Yanjiu is the property of Study on Optical Communications Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of University Chemistry is the property of Peking University, College of Chemistry & Molecular Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Computer Measurement & Control is the property of Magazine Agency of Computer Measurement & Control and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Industrial Minerals & Processing / Huagong Kuangwu yu Jiagong is the property of Industrial Minerals & Processing Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To probe int the interactions of pharmacokinetics between flavonoids and synephrine in fructus aurantii immaturus based on ultra performance liquid chromatography-triple quadrupole tandem mass spectrometry (UPLC-MS / MS), so as to provide scientific basis for the introduction of flavonoids as a quality and quantitative control index of fructus aurantii immaturus. METHODS: A total of 24 SD rats were extracted to be randomly divided into six groups ( n = 4), group A was administrated with synephrine + six kinds of categories of flavonoids (neohesperidin, naringin, narirutin, hesperidin, nobiletin and rhoifolin), group B was administrated with synephrine alone, group C was administrated with synephrine + naringin, group D was administrated with synephrine + neohesperidin, group E was administrated with six categories of flavonoids alone, group F was administrated with an equal volume of 0. 9% NaCl solution, all administered by gavage. The plasma was taken at different time points after administration, the contents of naringin, neohesperidin and synephrine in plasma were determined, and DAS 2. 0 software was used to calculate the pharmacokinetic parameters. The blood concentration was determined by using UPLC-MS / MS method. RESULTS: Clearance rate of neohesperidin in group A was (9 337. 88±8 373. 94) L/ (h·kg), significantly higher than (2 558. 22±610. 87) L/ (h·kg) in group E, with statistically significant difference (P<0. 05). The distribution volume of neohesperidin in group A and group D were respectively (2 549. 72±1 381. 42) L / kg and (1 668. 41± 394. 73) L / kg, significantly lower than ( 23 388. 87 ± 6 089. 53) L / kg in group E, with statistically significant differences ( P < 0. 05). The mean detention time of synephrine in group A was ( 2. 50 ± 0. 63) h, in comparison with (1. 62±0. 11) h, (1. 70±0. 17) h and (1. 57±0. 08) h of groups B, C and D, the differences were all statistically significant ( P < 0. 05 ). CONCLUSIONS: Synephrine has great effect on the clearance rate and distribution of neohesperidin, and the flavonoids in fructus aurantii immaturus can prolong the mean detention time of synephrine. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Harbin Institute of Technology. Social Sciences Edition / Haerbin Gongye Daxue Xuebao. Shehui Kexue Ban is the property of Harbin Institute of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of New Building Materials / Xinxing Jianzhu Cailiao is the property of New Building Materials Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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AIM: To investigate the regulatory role of retinoid X receptor （RXR） in oxidative stress response of rat type II alveolar epithelial cells（ AECII） induced by hypoxia/reoxygenation（ HR）. METHODS: The AECII were divided into control （C） group, HR group, HR+solvent dimethyl sulfoxide （DMSO） group （HD group）, HR+RXR agonist 9-cis-retinoic acid （9-RA） group （RA group）, and HR+RXR antagonist HX531 group （HX group）. Cell Counting Kit-8 （CCK-8） method was used to measure the cell viability. Immunofluorescence staining was used to detect the expression of surfactant protein A （SP-A） and RXRα in AECII. Kits were detected to the levels of superoxide dismutase （SOD） and malondialdehyde （MDA） in cells. Transmission electron microscopy was used to observe the ultrastructural changes of the cells. Western blot was used to detect the protein level of nuclear factor E2-related factor 2 （Nrf2）. RT-PCR was used to detect the expression level of Nrf2 mRNA. RESULTS: Compared with C group, the cell viability and SOD activity in HR, HD, RA and HX groups were decreased significantly （P<0. 05）, the MDA content were increased significantly （P<0. 05）, the Nrf2 mRNA and protein expression levels were decreased significantly （P<0. 05 or P<0. 01）, and the immunofluorescence expression of RXRα was significantly increased （P<0. 01）. Compared with HR and HX groups, the cells in RA group showed significantly increased cell viability （P<0. 05）, increased SOD activity（ P<0. 05）, decreased MDA content （P<0. 05）, increased Nrf2 mRNA and protein expression levels （P<0. 01）, and significantly increased immunofluorescence expression of RXRα （P<0. 01）. CONCLUSION: Hypoxia/reoxygenation can aggravate the oxidative stress response of rat AECII, and RXR agonist intervention can alleviate HR-induced rat AECII injury by inhibiting oxidative stress. [ABSTRACT FROM AUTHOR]

[Objectives]This experiment was based on the fertilizer yak as the research object, to explore different dietary concentrate to roughage ratio effect on the body metabolism of fattening yaks. It was expected to provide reference for the regulation and control of diet in Qinghai yaks in the process of large-scale, industrial and modern breeding. [Methods]15 yaks had been randomly divided into 3 groups. The yaks had been fed with different concentrates to roughage ratios(group A:concentrate:roughage=3:7, group B:concentrate:roughage=5:5, group C:concentrate:roughage=7:3). After regular feeding 90 days, these fasting yaks had been slaughtered during early morning. Then we collected the rumen fluid and the rumen epithelial tissue through 16S rRNA high-throughput sequencing, gas chromatography, RT-qPCR, and Western blot test methods to explore the changes of the structure of rumen bacterial flora, rumen fermentation parameters and the expression of volatile fatty acid(VFA)transport vector in rumen epithelium of house fed fattening yak in diets with different concentrate crude ratio. [Results]The ratio of concentrate to roughage significantly affected the structure of rumen bacterial flora. The results showed that the ratio of concentrate to roughage had significant effects on Firmicutes, Bacteroidetes, Spirochaetes, Lentisphaerae and Tenericutes in rumen bacteria of yaks. The relative abundances of Bacteroidetes, Spirochaetes and Lentisphaerae significantly increased with the increase of the proportion of concentrate(P<0.05). The relative abundances of Firmicutes and Tenericutes significantly decreased(P<0.05). On the level of the genus, with the increase of concentrate proportion, the relative abundance of Rikenellaceae RC9 gut group, Christensenellaceae R7 group, Saccharofermentans, Succiniclasticum and Lachnoclostridium significantly increased(P<0.05). Ruminococcus and Bacteroides in group C had a relative abundance significantly lower than group A(P<0.05). Prevotella, Pseudobutyrivibrio and Treponema in group B and group C had a relative abundance significantly higher than group A(P<0.05). The rumen pH and VFA were significantly affected by different concentrate-to-forage ratio diets. With the increase of concentrate-to-forage ratio, the rumen pH value of yak decreased significantly(P<0.05). The concentration of propionic acid, valeric acid and total VFA significantly increased(P<0.05), while the concentration of acetic acid and acetic acid/propionic acid significantly decreased(P<0.05). The concentration of butyric acid and isobutyric acid in group C were significantly higher than those in group A and group B(P<0.05). The results showed that downregulated in adenoma gene(DRA), putative anion transporter 1 gene(PAT1), monocarboxylate transporter 1 gene(MCT1)and monocarboxylate transporter 4 gene(MCT4), which were involved in the absorption and transport of VFA in the rumen epithelium increased significantly in mRNA level with the increase of the proportion of dietary concentrate(P<0.05).The anion exchanger 2 gene(AE2)significantly decreased(P<0.05). And the protein levels were consistent with mRNA. With the increase of the proportion of concentrate and roughage in the diet, the production performance of yaks, including the average daily gain, feed conversion ration and slaughter percentage also increased. And there was a significant difference among them(P<0.05). [Conclusions]High-concentrate diet could increase the relative abundance of non-cellulolytic bacteria in rumen of yak, and rapidly convert a large amount of energy feed and protein feed into VFA, which could provide energy for the body. VFA transporters in rumen epithelial cells are activated to increase their expression, and VFA transporters into the blood to enhance the lipid metabolism substrate, achieving the effect of rapid fattening ultimately. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Guangdong University of Technology is the property of Journal of Guangdong University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Electric Power Automation Equipment / Dianli Zidonghua Shebei is the property of Electric Power Automation Equipment Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Large Electric Machine & Hydraulic Turbine is the property of Large Electric Machine & Hydraulic Turbine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Segmental bone defects are prone to non-unions, and its treatment is a formidable clinical challenge. Additionally, the aging population and prevalence of osteoporosis-related fractures make it urgent to further explore a novel strategy to induce osteogenesis in this special population with limited bone generation ability. OBJECTIVE: To evaluate the novel strategy of bone marrow mesenchymal stem cells-loaded platelet-rich plasma combined with extracorporeal shock wave in reconstruction of segmental bone defects in osteoporosis. METHODS: The bone marrow mesenchymal stem cells pretreated by extracorporeal shock wave were co-cultured with platelet-rich plasma and the cell biocompatibility was tested by CCK-8 and live-death staining. Osteogenic differentiation of bone marrow mesenchymal stem cells was detected by alkaline phosphatase staining, alizarin red staining, and RT-PCR detection. New-Zealand rabbit models of osteoporosis were established and segmental bone defects of the radius were prepared. The combined treatment strategy of bone marrow mesenchymal stem cells-loaded platelet-rich plasma implantation and extracorporeal shock wave was used. The bone regeneration of radius samples was analyzed by Micro-CT and histological evaluation. RESULTS AND CONCLUSION: (1) In vitro, platelet-rich plasma combined with extracorporeal shock wave significantly promoted bone marrow mesenchymal stem cells proliferation and migration, as well as induced osteogenic differentiation of bone marrow mesenchymal stem cells by upregulating the deposition of calcium nodule, and expression of alkaline phosphatase, runt-related transcription factor-2 (Runx-2) and osteocalcin. (2) In vivo, Micro-CT analysis and histological evaluation indicated this combination strategy of bone marrow mesenchymal stem cells-loaded plateletrich plasma implantation combined with extracorporeal shock wave significantly enhanced bone regeneration in osteoporotic segmental bone defects. (3) The results indicated that this novel strategy of bone marrow mesenchymal stem cells-loaded platelet-rich plasma implantation combined with extracorporeal shock wave could improve the poor osteogenic microenvironment associated with osteoporosis and show the potential for enhancing healing in segmental bone defects with osteoporosis. [ABSTRACT FROM AUTHOR]

The reaction between acetone and iodine is a typical dynamic experiment. However, students are often troubled by the failure to record sufficient experimental data. Here, a fading reaction system was introduced based on the oxidation of Evans blue by potassium bromate in the presence of sodium nitrite. The reaction was a first-order reaction for both Evans blue and bromate, while nitrite exhibited a significant catalytic effect. Based on the apparent rate constants in the absence and presence of nitrite under different temperatures, the apparent activation energy was calculated. For students, the proposed experiment helps them acquire a deeper understanding of relevant chemical kinetics knowledge and develop comprehensive experimental ability. In addition, it is also an ideal substitute for the basic experiment, i.e., the reaction between acetone and iodine. [ABSTRACT FROM AUTHOR]

Gitelman综合征（GS）是由SLC12A3 基因突变引起的一种常染色体隐性遗传性肾小管疾 病, 以低钾代谢性碱中毒、低镁血症和低尿钙为特征。近年来越来越多的研究显示, GS患者可合并糖 代谢异常, 其机制尚不明确, 主要考虑与低血钾、低血镁和高醛固酮状态导致的胰岛素抵抗或胰岛素 分泌障碍有关, 低血镁可能在胰岛素抵抗的发生中起关键作用。该文总结了GS合并糖代谢异常的患 病情况、机制、治疗方案的相关进展, 以期引起内分泌科医师对GS合并糖代谢紊乱的重视, 改善GS合 并糖代谢异常患者的生活质量。. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Pathophysiology is the property of Jinan University, School of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Large Electric Machine & Hydraulic Turbine is the property of Large Electric Machine & Hydraulic Turbine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

文章介绍了基于31.786Gbaud/s光收发模块实现的32×100Gbit/s信号速率、2 080km标准单模光纤的实时相干光传输试验,信号采用PM-QPSK（偏振复用四相相移键控）调制格式。信号光源为单个激光器产生的32路波分复用子光载波,频率间隔为32GHz,频谱效率达到3.11bit/s/Hz。信号传输2 080km后,采用20%的FEC（前向纠错）编码时,Q值仍有1.2dB的余量。此外,还研究了光滤波器带宽与OSNR（光信噪比）代价的关系。25h挂机试验结果显示,信号接收纠错前误码率在1E-2以下,表明该传输系统稳定可靠。该系统为国内首个单光源3.2 Tbit/s实时传输试验系统,对提升现有100Gbit/s商用光纤传输系统的传输效率有较大的指导意义。

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Based on local records, documents and archival data, this paper investigated the introduction and popularization of maize in Anhui Province in the Qing Dynasty as a whole, then analyzed the reasons that cause the promotion difference in different regions. It was found that maize was first introduced to Anhui Province from Zhejiang Province during the reign of Yongzheng period, and Lujiang County in middle Anhui was the first place to introduce maize. The first peak period of maize popularization in Anhui happened during the reign Qianlong period when the population pressure was great, and the large-scale popularization was in the reign Jiaqing-Daoguang periods. The popularization of maize in Anhui showed a decreasing trend from the middle to the north and south in terms of the introduction time. From the point of view of the propagation speed, it presented an increasing trend from the north to south. The main reason why the introduction time and propagation speed of maize showed such a trend was the differences of natural environment, dietary customs and contradiction between people and land in various communities in Anhui Province. Among these factors, the contradiction between people and land was the fundamental reason for affecting its propagation speed. [ABSTRACT FROM AUTHOR]

AIM: To evaluate the role of nucleotide-binding oligomerization domain-like receptor protein 3 （NLRP3） inflammasome-mediated pyroptosis in rat lung ischemia/reperfusion injury （LIRI） and the intervention effects of ischemic post-conditioning （I-post-C） treatment. METHODS: Twenty SPF grade male SD rats aged 6 to 8 weeks were randomly divided into 4 groups: control group, LIRI group, I-post-C group, and INF39+LIRI group. After the experiment, the rats were sacrificed, and tissue samples from the left lung were harvested. The morphological changes of the lung tissues were examined by ordinary light microscopy. The level of reactive oxygen species （ROS） was evaluated by dihydroethidium staining. The changes of oxidative stress indicators malondialdehyde（ MDA）, glutathione（ GSH） and myeloperoxidase（ MPO）, as well as the level of caspase-1, were detected using commercially available kits. The levels of interleukin-1β （IL-1β） and IL-18 in the lung tissue were detected by ELISA. The mRNA levels of NLRP3, IL-1β, IL-18 and thioredoxin-interacting protein （TXNIP） were detected by RT-qPCR. The protein levels of NLRP3, N-terminal fragment of gasdermin D （GSDMD-N）, cleaved caspase-1 and TXNIP were detected by Western blot. The TXNIP expression was also detected by immunofluorescence. RESULTS: The surface of the left lung in LIRI group was interspersed with dark red and light red, with brittle texture, obvious rupture of the alveolar wall, deformation and collapse of the alveoli, infiltration of neutrophils and red blood cells, and interstitial edema. The LIRI caused the production of a large number of ROS （P<0. 01）. Compared with control group, LIRI group showed significant increases in MDA content of and MPO activity, and a significant decrease in GSH content （P<0. 01）. The mRNA and protein levels of TXNIP were significantly up-regulated （P<0. 05）. The mRNA levels of IL-1β and IL-18 in the lung tissue were noticeably increased （P<0. 01）, and the mRNA and protein levels of NLRP3 were significantly increased （P<0. 05）. The protein levels of GSDMD-N and cleaved caspase-1 were significantly increased, and the activity of caspase-1 in the lung tissue was dramatically increased （P< 0. 01）. Compared with LIRI group, lung tissue injury in I-post-C group was significantly attenuated. The ROS accumulation was significantly reduced, the MDA content and MPO activity in I-post-C group were decreased （P<0. 05）, and the content of GSH was increased significantly （P<0. 01）. The mRNA and protein levels of TXNIP were down-regulated （P< 0. 05）. Compared with LIRI group, the mRNA level and tissue content of IL-1β and IL-18 in the lung tissue of I-post-C and INF39+LIRI groups were significantly decreased （P<0. 05）. The NLRP3 mRNA and protein levels in the lung tissue were significantly down-regulated, and the protein levels of GSDMD-N and cleaved caspase-1 were significantly decreased （P<0. 05）. CONCLUSION: The I-post-C alleviates LIRI in rats, and its mechanism may be related to the regulation of ROS-TXNIP-NLRP3-GSDMD signaling pathway. [ABSTRACT FROM AUTHOR]

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