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【目的】了解生存蛋白Survivin在T细胞非霍奇金淋巴瘤（T—NHL）中的表达，以及Survivin表达与预后的关系。【方法】用免疫组化S-P法检测83例T细胞NHL组织Survivin表达情况，分析Survivin表达与预后的关系。【结果】Survivin表达阴性10例（12％），表达阳性73例（88％），Survivin表达与病理类型、性别、年龄、B症状、结外病变数、PS、分期、LDH水平、IPI等临床特征均无相关性（P〉0．05）。78例接受了化疗，大多数采用CHOP方案化疗，全组CR率45％，有效率86％，Survivin阴性者CR率60％，阳性者43％（P〉0．05）。中位随访22月（1—76月），全组5年生存率31％，Survivin表达阳性的T—NHL患者5年生存率明显低于Survivin表达阴性患者（21％比70％，P〈0．001）。多因素分析显示Survivin表达是T细胞NHL的独立预后指标。【结论】Survivin在T细胞NHL表达上调，Survivin阳性T—NHL患者5年生存率低于Survivin阴性者，Survivin表达可能为T细胞NHL预后的独立指标。

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[Objective] The effect of different combined application rates of organic fertilizer and chemical fertilizer on nitrogen supply capacity and greenhouse gas emission of tobacco-growing soil is explored, which provides scientific guide for improvement of yield and quality of tobacco leaves, adjustment and perfection of fertilization method. [Method] Rapeseed cake (RC), pig manure (PM), carbon-based organic fertilizer (BOF) and peanut straw (PS) were selected as the test organic materials, and the nitrogen substitution ratio of chemical fertilizers was set at two levels, 30% and 50% respectively.Through the pot experiment, the differences in agronomic characteristics, biomass, soil mineral nitrogen content, soil organic carbon content, greenhouse gas emissions of flue-cured tobacco between treatments were compared. [Result] Compared with chemical fertilizer treatment (CK), except for BOF treatment, other combined organic fertilizer treatments all reduced the mineral nitrogen content of the soil by 22.9%-57.84% (resettling growth stage), 4.97%-66.04% (prosperous growth period), 25.59%-83.82% (budding period), 33.58%-68.90% (mature period) .Except for peanut straw treatment, other organic fertilizer treatments did not significantly reduce the biomass of flue-cured tobacco roots, stems and leaves.Only the combined application of pig manure and peanut straw treatment significantly increased CO2 emissions by 23.74%-33.40% and 61.75%-87.54% respectively.Only when the proportion of organic materials was 50%, the N2O emission was significantly increased, and the increase was 7.73-21.89 times.The combined application of organic materials increased the total nitrogen content of the soil by 1.56%-20.68%, and also significantly increased the total soil carbon content by 2.77%-16.63%.Rapeseed cake treatment significantly reduced soil C/N ratio, while peanut straw treatment significantly increased soil C/N ratio, but pig manure and carbon-based organic fertilizer treatment had no significant effect on soil C/N ratio. [Conclusion] Comprehensive comparison showed that carbon-based organic fertilizer was suitable for tobacco planting.From the aspects of nitrogen supply capacity of tobacco soil, biomass of tobacco plant and N2O emission, the proportion of organic materials should be 30%, and shouldnot be higher than 50%.In order to maintain the carbon and nitrogen balance of tobacco planting soil, rapeseed cake with low C/N ratio and peanut straw with high C/N ratio should not be applied separately and continuously. [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Agro-Environment Science is the property of Journal of Agro-Environment Science Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Agricultural Resources & Environment / Nongye Ziyuan yu Huanjing Xuebao is the property of Journal of Agricultural Resources & Environment Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agricultural Resources & Environment / Nongye Ziyuan yu Huanjing Xuebao is the property of Journal of Agricultural Resources & Environment Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Southwest China Journal of Agricultural Sciences is the property of Editorial Department of Southwest China Journal of Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Agricultural Resources & Environment / Nongye Ziyuan yu Huanjing Xuebao is the property of Journal of Agricultural Resources & Environment Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)