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Copyright of Chinese Journal of Oncology is the property of Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Cancer Research on Prevention & Treatment is the property of Cancer Research on Prevention & Treatment Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

High-risk human papillomavirus ( HPV) -related cancers consist of cervical cancer, anal cancer, penile cancer, vulvar cancer, vaginal cancer, and head and neck cancer ( HNC). Of these, the disease burden of HNC is second only to cervical cancer. HNC mostly originates from malignant lesions of squamous epithelial cells and mainly includes oral cavity cancer, pharyngeal cancer ( including nasopharyngcal cancer, oropharyngeal cancer, and hypopharyngcal cancer), and laryngcal cancer. Tobacco use, alcohol abuse, and HPV infection arc three primary risk factors. Recently, there is an upward trend of HNC incidence globally, especially in high-income countries. In China, the disease burden and trends of HPV-related HNC arc still not clear. A few small sample size and single-center studies suggest a high HPV prevalence and increasing trend in HNC. Methodological differences in HPV testing and regional variabilities still exist among these studies. Among the anatomic sites, oropharyngeal cancer has been shown to be caused by HPV infection, hut the association of HPV with other sites is still under debate. In addition, there is a paucity of relevant studies. Here, this review narrates the association between HPV infection and HNC, compares the differences between global and Chinese studies, and then explores the importance of HPV infection in various anatomical sites. The main objective is to highlight the research on HPV-related HNC and promote relevant prevention and treatment programs. [ABSTRACT FROM AUTHOR]

Copyright of Practical Oncology Journal is the property of Journal of Practical Oncology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Oncology is the property of Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Oncology is the property of Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Oncology is the property of Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Practical Oncology Journal is the property of Journal of Practical Oncology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To evaluate the compliance rate and its impact factors of liver cancer screening for high-risk groups in urban areas of Henan Province from 2013 to 2019. Methods Residents of 40-74 years old in 8 cities of Henan province were selected to investigate the risk factors and liver cancer risk assessment. Subjects with high risk of liver cancer received AFP combined ultrasonography for screening. Chi-square tests were used to compare the differences in liver cancer screening participation rates between groups. Multivariate logistic regression models were applied to explore the potential factors correlating to the compliance of liver cancer screening. Results Overall, 3 6781 participants who met the inclusion criteria were included in this analysis, and 17 241 of them took the following liver cancer screening, yielding a participation rate of 46. 87%. The participation rate varied greatly across cities, ranging from 62. 50% to 38.59%. Moreover, the participation rate varied greatly across periods, ranging from 52.77% in 2014-2015 to 38.14% in 2013-2014. The multivariate Logistic regression analyses showed that: female, older, high education degree, cigarette and alcohol intake, infrequent physical exercise, chronic hepatitis B, chronic hepatitis C, fatty liver, gallstones and a family history of liver cancer were inclined to accept liver cancer screening (P<0.05). Conclusions The overall participation rate of liver cancer screening among high-risk population is less than 50% in urban areas of Henan Province. Implement of effective interventions targeting the specific high-risk populations might improve the overall compliance rate of liver cancer screening in the future. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Oncology is the property of Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To evaluate the performance of Hybribio human papillomavirus ( HPV) typing test kit for high risk HPV-DNA typing detection in screening of cervical precancer lesions. Methods A total of 9914 women were recruited in Henan, Shanxi, and Guangdong provinces from June to July 2017. All women underwent HPV DNA test. The women who diagnosed as HPV positive and cytological examination ⩾ atypical squamous cells of undetermined significance ( ASCUS) or HPV negative and cytological examination ⩾ low-grade squamous intraepithelial lesions ( LSIL) underwent colposcopy biopsy and pathological examination. Using the pathological diagnosis as the gold standard, the sensitivity, specificity, positive predictive value ( PPV), negative predictive value ( NPV), and 95% confidence interval (Cl) of high-risk HPV and HPV 16/18 tests were calculated. Results The mean age of 9914 subjects was ( 45.0±9.3) years old. Among them,1302 subjects were detected as high risk HPV positive, including 211 of HPV16 positive and 64 of HPV18 positive. According to the pathological gold standard of cervical intraepithelial neoplasia grade 2 ( CIN2 ) or worse, the sensitivity mid specificity of high risk-HPV and HPV 16/18 for triaging ASCUS women were 90.6%· ( 95%CI: 75.8%-96.8%·) and 78.0% ( 95% CI: 74.5%-81. 2%) as well as 56.3% (95%CI: 39.3%-71.8%) and 95.7% ( 95%CI: 93.8%-97.1%), respectively. The sensitivity and specificity of high risk-HPV and HPV 16/18 for cervical precancer lesions screening were 95.1% ( 95%CI: 88.1%-98.1%) and 87.6%·(95%CI: 86.9%-88.2%) as well as 65.9% (95%·CI: 55.1%-75.2%) and 97 .8% ( 95% CI: 97. 5%-98.1 %), respectively. Conclusions The Hybribio HPV test kit has a relative high sensitivity and specificity for cervical precancer lesions screening and ASCUS triaging. It is reliable for HPV DNA detection mid cervical cancer screening. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Oncology is the property of Chinese Journal of Oncology / Zhonghua Zhongliu Zazhi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Ｏｂｊｅｃｔｉｖｅ　Ｔｏ ａｎａｌｙｚｅ ｔｈｅ ｅｆｆｉｃａｃｙ ｏｆ ｅｎｄｏｓｃｏｐｉｃ ｓｃｒｅｅｎｉｎｇ ｆｏｒ ｇａｓｔｒｉｃ ｃａｎｃｅｒ ｉｎ ｒｕｒａｌ ｐｏｐｕｌａｔｉｏｎ ｉｎ ｈｉｇｈ ｒｉｓｋ ａｒｅａｓ ｏｆ ｕｐｐｅｒ ｇａｓｔｒｏｉｎｔｅｓｔｉｎａｌ ｃａｎｃｅｒ ｉｎ Ｈｅｎａｎ ｐｒｏｖｉｎｃｅ． Ｍｅｔｈｏｄｓ　Ｓｕｂｊｅｃｔｓ ａｇｅｄ ４０⁃６９ ｙｅａｒｓ ｉｎ ｔｈｅ ｈｉｇｈ ｒｉｓｋ ａｒｅａｓ ｗｅｒｅ ｓｅｌｅｃｔｅｄ ｔｏ ｐａｒｔｉｃｉｐａｔｅ ｉｎ ｔｈｅ ｅｎｄｏｓｃｏｐｉｃ ｓｃｒｅｅｎｉｎｇ ｂａｓｅｄ ｏｎ ｔｈｅ ｃｌｕｓｔｅｒ ｓａｍｐｌｉｎｇ， ａｎｄ ｓｃｒｅｅｎｉｎｇ⁃ｐｏｓｉｔｉｖｅ ｓｕｂｊｅｃｔｓ ｗｅｒｅ ｓａｍｐｌｅｄ ｆｏｒ ｐａｔｈｏｌｏｇｉｃａｌ ｅｘａｍｉｎａｔｉｏｎ． Ｔｈｅ ｄａｔａ ｏｆ ｓｃｒｅｅｎｉｎｇ ｗｅｒｅ ｓｕｍｍａｒｉｚｅｄ ａｎｄ ｔｈｅ ｄｅｔｅｃｔｉｏｎ ｒａｔｅｓ ｏｆ ｓｅｖｅｒｅ ｃｈｒｏｎｉｃ ａｔｒｏｐｈｉｃ ｇａｓｔｒｉｔｉｓ， ｓｅｖｅｒｅ ｉｎｔｅｓｔｉｎａｌ ｍｅｔａｐｌａｓｉａ， ｌｏｗ ｇｒａｄｅ ｉｎｔｒａｅｐｉｔｈｅｌｉａｌ ｎｅｏｐｌａｓｉａ， ｈｉｇｈ ｇｒａｄｅ ｉｎｔｒａｅｐｉｔｈｅｌｉａｌ ｎｅｏｐｌａｓｉａ， ｅａｒｌｙ ａｎｄ ｍｉｄｄｌｅ⁃ｌａｔｅ ｃａｎｃｅｒ ｗｅｒｅ ｃａｌｃｕｌａｔｅｄ， ａｎｄ ｔｈｅ ｃｏｎｓｔｉｔｕｅｎｔ ｒａｔｉｏ ｏｆ ｅａｒｌｙ ｃａｎｃｅｒ ｃａｓｅｓ ｗａｓ ｃａｌｃｕｌａｔｅｄ． Ｔｈｅ ｄｅｔｅｃｔｉｏｎ ｒａｔｅｓ ａｎｄ ｅａｒｌｙ ｄｉａｇｎｏｓｉｓ ｒａｔｅｓ ｆｏｒ ｔｈｅ ｆｉｒｓｔ ｒｏｕｎｄ ｓｃｒｅｅｎｉｎｇ ａｎｄ ｆｏｌｌｏｗ⁃ｕｐ ｓｃｒｅｅｎｉｎｇ ｗｅｒｅ ｃｏｍｐａｒｅｄ． Ｒｅｓｕｌｔｓ　Ｉｎ ｔｈｅ ５ ｙｅａｒｓ， ａ ｔｏｔａｌ ｏｆ ８８ ２６３ ｓｕｂｊｅｃｔｓ ｗｅｒｅ ｅｎｄｏｓｃｏｐｉｃａｌｌｙ ｅｘａｍｉｎｅｄ ｉｎ ｔｈｅ ｆｉｒｓｔ ｒｏｕｎｄ ｓｃｒｅｅｎｉｎｇ ａｎｄ ４ ００４ ｓｕｂｊｅｃｔｓ ｗｅｒｅ ｄｉａｇｎｏｓｅｄ ｗｉｔｈ ｌｏｗ ｇｒａｄｅ ｉｎｔｒａｅｐｉｔｈｅｌｉａｌ ｎｅｏｐｌａｓｉａ ｏｒ ａｂｏｖｅ （ｔｈｅ ｄｅｔｅｃｔｉｏｎ ｒａｔｅ ｗａｓ ４．５４％）， ｉｎ ｗｈｉｃｈ ３ ２５６ ｃａｓｅｓ ｗｅｒｅ ｗｉｔｈ ｌｏｗ ｇｒａｄｅ ｉｎｔｒａｅｐｉｔｈｅｌｉａｌ ｎｅｏｐｌａｓｉａ （ｔｈｅ ｄｅｔｅｃｔｉｏｎ ｒａｔｅ ｏｆ ３．６９％）， ３６６ ｃａｓｅｓ ｗｉｔｈ ｈｉｇｈ ｇｒａｄｅ ｉｎｔｒａｅｐｉｔｈｅｌｉａｌ ｎｅｏｐｌａｓｉａ （ｔｈｅ ｒａｔｅ ｏｆ ０．４１％）， １９９ ｃａｓｅｓ ｗｉｔｈ ｅａｒｌｙ ｃａｎｃｅｒ （ｔｈｅ ｒａｔｅ ｏｆ ０．２２％） ａｎｄ １８３ ｃａｓｅｓ ｗｉｔｈ ｍｉｄｄｌｅ⁃ｌａｔｅ ｃａｎｃｅｒ （ｔｈｅ ｒａｔｅ ｏｆ ０．２１％）． Ｔｈｅ ｎｕｍｂｅｒ ｏｆ ｃａｓｅｓ ｏｆ ｈｉｇｈ ｇｒａｄｅ ｉｎｔｒａｅｐｉｔｈｅｌｉａｌ ｎｅｏｐｌａｓｉａ ａｎｄ ｅａｒｌｙ ｃａｎｃｅｒ ｗａｓ ５６５ ａｎｄ ｔｈｅ ｅａｒｌｙ ｄｉａｇｎｏｓｉｓ ｒａｔｅ ｗａｓ ７５．５３％． １ ８９４ ｓｕｂｊｅｃｔｓ ｗｉｔｈ ｓｅｖｅｒｅ ｃｈｒｏｎｉｃ ａｔｒｏｐｈｉｃ ｇａｓｔｒｉｔｉｓ， ｓｅｖｅｒｅ ｉｎｔｅｓｔｉｎａｌ ｍｅｔａｐｌａｓｉａ ａｎｄ ｌｏｗ ｇｒａｄｅ ｉｎｔｒａｅｐｉｔｈｅｌｉａｌ ｗｅｒｅ ｆｏｌｌｏｗｅｄ ｕｐ ｗｉｔｈ ａ ｃｏｍｐｌｉａｎｃｅ ｏｆ ６６．３２％． Ａ ｔｏｔａｌ ｏｆ ４５ ｃａｓｅｓ ｏｆ ｅａｒｌｙ ｃａｎｃｅｒ ｗｅｒｅ ｄｉａｇｎｏｓｅｄ， ｗｉｔｈ ａ ｄｅｔｅｃｔｉｏｎ ｒａｔｅ ｏｆ ２．３８％ ａｎｄ ｅａｒｌｙ ｄｉａｇｎｏｓｉｓ ｒａｔｅ ｏｆ １００％． Ｔｈｅ ｄｅｔｅｃｔｉｏｎ ｒａｔｅ ａｎｄ ｅａｒｌｙ ｄｉａｇｎｏｓｉｓ ｒａｔｅ ｉｎ ｔｈｅ ｆｏｌｌｏｗ⁃ｕｐ ｓｃｒｅｅｎｉｎｇ ｗｅｒｅ ｂｏｔｈ ｓｔａｔｉｓｔｉｃａｌｌｙ ｓｉｇｎｉｆｉｃａｎｔｌｙ ｈｉｇｈｅｒ ｔｈａｎ ｔｈａｔ ｉｎ ｔｈｅ ｆｉｒｓｔ ｒｏｕｎｄ ｓｃｒｅｅｎｉｎｇ （Ｐ＜０．０１ ｆｏｒ ｂｏｔｈ）． Ｃｏｎｃｌｕｓｉｏｎ Ｔｈｅ ｅｆｆｉｃａｃｙ ｏｆ ｅｎｄｏｓｃｏｐｉｃ ｓｃｒｅｅｎｉｎｇ ｆｏｒ ｇａｓｔｒｉｃ ｃａｎｃｅｒ ｉｓ ｓｉｇｎｉｆｉｃａｎｔ ｉｎ ｈｉｇｈ ｒｉｓｋ ａｒｅａｓ ｏｆ ｕｐｐｅｒ ｇａｓｔｒｏｉｎｔｅｓｔｉｎａｌ ｃａｎｃｅｒ， ａｎｄ ｉｍｐｒｏｖｉｎｇ ｔｈｅ ｑｕａｌｉｔｙ ｏｆ ｆｏｌｌｏｗ⁃ｕｐ ｓｃｒｅｅｎｉｎｇ ｗｉｌｌ ａｃｈｉｅｖｅ ａ ｂｅｔｔｅｒ ｐｅｒｆｏｒｍａｎｃｅ ｏｆ ｔｈｅ ｓｃｒｅｅｎｉｎｇ． [ABSTRACT FROM AUTHOR]