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目的比较单精子冷冻和常规冷冻对显微取精患者的胚胎培养及妊娠影响。方法回顾性分析自2018年1月至2021年12月于中山大学附属第六医院生殖医学研究中心行显微镜取精术患者的临床资料，行单精子冷冻共39例307枚成熟卵子为单精子冷冻组，通过SPSS统计软件倾向性评分匹配女方基本助孕信息1：1匹配选择对照组，为常规冷冻组，共410枚成熟卵子，分析单精子冷冻与常规冷冻两组的受精、胚胎培养及移植后妊娠情况。结果单精子冷冻组和常规冷冻组的年龄、体质量指数（BMI）、不孕年限、基础基础卵泡刺激素（FSH）、基础黄体生成素（LH）、基础雌二醇（E2）、抗苗勒管激素（AMH）、窦卵泡计数（AFC）、获卵数、移植胚胎数等一般资料的比较，差异均差异无统计学意义（P>0.05）；两组的受精率、可利用胚胎率、优质胚胎率比较分别为65.8% vs. 60.49%、67.82% vs. 58.87%、70.80% vs. 75.34%，差异均无统计学意义；两组的临床妊娠率为45.45% vs. 70.0%，有统计学差异（P=0.049）。结论显微取精患者若获取精子极少，为增加每颗精子利用机会以及保证后续助孕精子解冻后获取精子，单精子冷冻可为有效选择，但临床妊娠率下降，因例数限制，对后续妊娠的影响还需增加例数再观察分析。

综合智慧能源作为能源互联网产业发展的重要业态，已成为促进可再生能源利用、提高能源系统能效与降低用能成本的重要抓手。但当前综合智慧能源概念边界模糊，且具有多元主体博弈、异质能流耦合集成、技术路线复杂多样的特征。因此，科学、系统、可操作的绩效评价是保障综合智慧能源规划设计、优化决策与项目经济效益的必要理论指导。在综述综合智慧能源相关评价体系的基础上，从能源利用、环境友好、经济社会以及综合智慧4个维度，以园区或区域综合智慧能源为对象，归纳评述了当前综合智慧能源绩效评价的多维度指标。一是明确了41个定量及定性绩效评价指标的定义、计算方式以及指标的正逆性，并对指标进行了图形化分类与归纳；二是研判了可再生能源替代率、利用率、渗透率等相似指标的区别及其应用场景，指明了包括能值可持续指数、需求侧互动等综合智慧能源未来应侧重的评价指标。同时，系统阐述了综合智慧能源绩效评价体系的非劣解、归一化和赋权重等架构方式以及绩效评价的步骤，并从学术研究、产业应用以及标准化方面对综合智慧能源绩效指标进行了展望。

城市能源转型的量化评价有助于城市经济社会的可持续发展，特别是对工业型城市能源系统的转型提供指导。但能源转型的综合评价面临多维度变量、多结构耦合以及多层次结构的挑战。以苏州市为例，提出基于解释结构模型及层次分析法的工业型城市能源转型的综合评价体系，在此基础上，通过二元对比，获得用于量化工业城市能源转型的综合评价模型。分析苏州2013—2018年的城市能源转型发展过程，得出苏州城市能源转型程度总体呈上升进步趋势，其中能源效率、能源结构、产业发展的进步最为显著，但电力自给率从79%下降至70%，能源安全压力增加，供能能力的得分呈波动上升趋势。能耗强度得分从2013—2017年逐年下降，2018年有所上升，能耗强度控制的形势严峻；2017年和2018年的研发强度得分低于2016年，需要进一步加大投入。最后，为苏州后续的能源转型发展提出5点建议。

电力能源系统的绿色发展关系经济活动的可持续发展，因此，电力能源系统的定量可持续性评价是“碳中和”目标下能源结构转型评价的关键工作。为定量统一分析不同发电技术的能量、经济及环境效益，首先采用能值分析理论对光伏、风电、水电、燃气及燃煤5种发电模式的能值可持续指数进行分析，发现现有技术经济水平下风电的能值可持续指数最优。其次，综合考虑能值可持续指数、发电效率、全生命周期成本3个维度指标，基于灰色关联分析法构建了计及能值的中国电力能源系统可持续性综合评价体系，量化分析了2020—2050年中国电力结构由以煤炭为主转向以清洁能源风光为主的可持续性。所提的能值可持续性评价方法，能够为区域能源转型的量化研判提供参考。

提出了一种新型光缆实时监测系统的设计方案 .系统通过光耦合器对每根光纤的光信号取样 ,然后对其光功率进行测试 ,将测试结果送到中央控制器进行计算、分析和处理 ,显示出测量数据 ,并根据处理结果控制光开关进行切换 ,再通过波分复用器 （ WDM）使故障光纤接入光时域反射计 （ OTDR）进行上下测试 .

基于LabVIEW虚拟仪器平台,研制了一套可调谐取样光栅分布布拉格反射式（Sampled Grating Distributed Bragg Reflector,SG-DBR）激光器的波长自动测试控制系统。该系统能对四段式SG-DBR激光器进行电流扫描,采集、分析其输出光谱,生成SG-DBR激光器的“波长-电流”数据查询表;并且通过调用数据查询表,实现对SG-DBR激光器输出波长的控制。

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A vegetation buffer strip is an important spatial barrier in rivers and lakes. It is used to alleviate the direct interference of human activities on rivers and lakes and block agricultural nonpoint source pollution. Eight buffer strips were designed in a small watershed Dingyuan in Zhangshan to systematically study the effect of interception provided by different types of buffer strips on pollutants such as N and P in farmland. Combined with natural rainfall methods, the reduction effects of different buffer strips on surface runoff and its main pollutants such as total N (TN), total P (TP), and chemical oxygen demand (COD) were observed for two years. The results showed that forest land and 3° and 8° cross-ridge tillage buffer had the highest runoff interception efficiency, with interception rates of 62.4%, 52.0%, and 60.6% for TN, TP, and COD, respectively. The runoff increased first and then decreased with the increase of rainfall intensity. Compared with the 8° slope treatment, the sediment reduction rates of the cultivated land buffer zone in the downhill (3°) treatment for vertical ridge and cross-ridge were 53.3% and 50.9%. The nutrient loss of rainfall runoff on the slope was mainly composed of N and organic matter, the average interception rate of NH+4-N in the runoff was as high as 95.2%. All buffer strips had good retention effect on TP in the runoff, and the loss of CODMn on the slope of 3° and 8° cross-ridge cultivation was the lowest, and the interception rate reached 53.0% and 58.6%. Our results indicated that the presence of high coverage vegetation and developed roots in the forest buffer strip can effectively slow down the erosion caused by rainfall on the surface and reduce runoff and nutrient loss. The implementation of cross-ridge cultivation in rural hilly and mountainous areas in the south is also an effective measure to retain runoff and reduce the risk of nonpoint source pollution. [ABSTRACT FROM AUTHOR]

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N6-methyladenosine (m6A) is the most prevalent modification that regulates gene expression in eukaryotes. It regulates splicing, degradation, stability, and translation of RNA. Numerous studies have demonstrated the close association between m6A methylation and tumor development, highlighting its crucial role in regulating tumor immune response. The m6A modification actively participates in governing immune cell differentiation and maturation as well as modulating anti-tumor immune responses. Within the tumor microenvironment, m6A modification can also impact the recruitment, activation, and polarization of immune cells, thereby either promoting or inhibiting tumor cell proliferation and metastasis. Consequently, it plays a pivotal role in reshaping the tumor immune microenvironment. In recent years, immunotherapy for tumors has been increasingly applied to clinical practice with notable success achieved through approaches such as immune checkpoint inhibitor therapy and adoptive cell immunotherapy. Targeting m6A modifications to interfere with the immune system, such as targeting dysregulated m6A regulators through small molecule inhibitors and inducing immune cell reprogramming, can improve anti-tumor immune response and strengthen immune cells′ ability to recognize and kill tumor cells. The m6A modification represents a novel avenue for potential clinical application within tumor immunotherapy. This review provides a comprehensive summary of the regulatory impact of m6A methylation modification on immune cells in the context of cancer, while also delving into novel targets for tumor immunotherapy. [ABSTRACT FROM AUTHOR]

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In this paper, the complexation characteristics of CdTe QDs using butyrylcholine and thiocholine as capping agents were studied with density functional theory (DFT). The stable complexation configurations were first optimized, based on which the relevant adsorption energies, charge densities, UV-Vis absorption spectr and frontier molecular orbital were calculated. It is found that the adsorption energy of butyrylcholine on CdTe QDs is very small, and the electron interaction between butyrylcholine and CdTe QDs is quite weak, which therefore can be attributed as to physical adsorption. In the meantime, the absorption intensity of ultraviolet and visible light is weak as well. In contrast, the electron interaction between thiocholine and CdTe QDs is strong, which is chemical adsorption, and the absorption intensity of ultraviolet and visible light is strong. The research results provide theoretical support for the detection of butyrylcholinesterase using CdTe QDs in the experiment. [ABSTRACT FROM AUTHOR]

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The hunting ceremony in the Qing Dynasty played a unique role in the inheritance and innovation of the ancient ritual system and ritual righteousness. The hunting-themed Fu in the dynasty is numerous and unique. These Fu works have rich content and elaborate description while are functional in clarifying classic reasons and expressing ironies. The investigation of these characteristics is beneficial to the study of the ritual and music forms of Fu in the unified state, and also contributes to the in-depth study of the relationship between literature and classics in the Qing Dynasty. [ABSTRACT FROM AUTHOR]