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Copyright of Journal of Agricultural Science & Technology (1008-0864) is the property of Journal of Agricultural Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Hypoxia inducible factors (HIF) are hypoxia-sensitive transcription factors that are the primary regulators of the cellular response to hypoxia. Hypoxia inducible factors induce inflammation, lipid metabolism, endothelial dysfunction, proliferation of vascular smooth muscle cells (VSMC), and regulate the development of cardiovascular diseases (CVD). This paper reviews the role of hypoxia inducible factors in CVD and the progress of the mechanism of action in recent years, and discusses the role and mechanism of hypoxia inducible factors on vascular constituent cell types and its relationship with the occurrence and development of CVD. It can provide a reference for analyzing the pathogenesis of CVD and discovering new therapeutic targets. The aim is to provide a theoretical reference for further understanding the role and mechanism of hypoxia inducible factors in the pathogenesis of CVD, and to provide a basis for the design of novel effective therapeutic agents targeting hypoxia inducible factors. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Biochemistry & Molecular Biology is the property of Editorial Office of Chinese Journal of Biochemistry & Molecular Biology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Diabetes Mellitus is the property of Chinese Journal of Diabetes Mellitus and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Syzygium grijsii, an evergreen shrub of Myrtaceae and Syzygium, has good prospects for exploitation, but its chloroplast genome characteristics and phylogenetic relationships have not been reported. To fill the gap in the genomics of S. grijsii, a systematic study of the chloroplast genome of S. grijsii was conducted in this paper. Illumina high-throughput sequencing was used to perform complete assembly in the GetOrganelle platform, and the assembled data were also used to analyze the structural features and phylogenetic relationships of the S. grijsii chloroplast genome, including the structure, function and characteristics of the S. grijsii chloroplast genome, codon preference analysis, comparative analysis of the chloroplast genome and phylogenetic analyses. The results were as follows:(1)The chloroplast genome of S. grijsii was 158 591 bp in size, which contained 129 genes. Among them, 8 were rRNA genes, 37 were tRNA genes and 84 were protein-coding genes. The analysis detected 39 repetitive sequences and 84 SSR loci.(2)Codon preference analysis revealed that there was a bias towards A/U at the ends of the S. grijsii chloroplast genome, and the most used codon was the one encoding leucine.(3)In comparison with closely related species, the boundary length of S. grijsii was conserved, and the gene species at the boundary were similar to several Syzygium species; the S. grijsii chloroplast genome had a high degree of variability in the LSC and SSC regions, with 45 sites of 0.010 < Pi < 0.015 and a high level of nucleotide diversity.(4)Phylogenetic analysis showed that S. grijsii was most closely related to S. jambos, S. forrestii and S. cumini, followed by S. malaccense. The study concluded that S. grijsii had a conserved chloroplast genome structure with distinct features, sequence similarity and nucleotide diversity compared to Syzygium species, and affinity between it and various Myrtaceae species. In this paper, the genomic characterization and phylogenetic analysis of the chloroplast genome of S. grijsii are conducted to lay the theoretical foundation for the identification and exploitation of the germplasm resources of S. grijsii. [ABSTRACT FROM AUTHOR]

[Objective] The characteristics of the Syzygium chloroplast genomes, codon usage patterns and phylogenetic analyses were carried out. The phylogenetic relationships and codon preferences of Syzygium were explored to promote the further exploitation of its medicinal value. [Method] In the study, the chloroplast genome sequences of Syzygium rubrum obtained by Illumina high-throughput sequencing technology and the five species of Syzygium obtained directly from NCBI were subjected to analyze the chloroplast genome characteristics, codon usage patterns, and phylogenetic relationships using Rstudio and other software. [Result] The IR region of the chloroplast genome of Syzygium was relatively conservative, the non-coding regions of LSC and SSC regions had lots of variations, and the coding region was relatively conservative, but the ycfl gene in the coding region of six species showed obvious variability; Most species of Syzygium were clustered in the same large branch as eucalyptus; The codon preference analysis showed that the contents of GC, GC1, GC2 and GC3 were all stable around the same value, the lowest content of GC3 was only about 28%, and 29 of the 30 high-frequency codons with RSCU > 1 ended in A/U; The maximum correlation coefficient between GC3 and GC12 was 0. 141, which did not reach a significant level; The ENC ratio was most distributed between 0.05 and 0.15. [Conclusion] The chloroplast genome of Syzygium was highly conserved and closely related to Eucalyptus. The third codon prefered to end with A/U, and the codon use pattern was mainly affected by natural selection as well as mutation. The common optimal codon of six species of Syzygium, such as CGU, AGU, AAA, GCU, GGU, GUA, and GAA, was the optimal codon of the chloroplast genome of Syzygium. [ABSTRACT FROM AUTHOR]

Copyright of Frontiers of Clinical Medicine is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 探究正念减压疗法结合助产士全程护理在初产妇自然分娩中的应用效果和价值. 方法 回顾性分析 2019 年 1 月至 2022 年 6 月于江苏省张家港市第一人民医院进行自然分娩的 92 名初产妇的临床资料,按干预方式的 不同将其分为 2 组,其中,对照组 47 名初产妇开展助产士全程护理,观察组 45 名初产妇在助产士全程护理的基础上 加用正念减压疗法. 对比 2 组产妇的干预效果. 结果 观察组在分娩时的疼痛控制优良率较对照组更高,产后 2 h 和 24 h 的出血量均较同期对照组更少,第一产程、第二产程、第三产程和总产程均比对照组更短,差异均有统计学意 义(P 均 < 0. 05). 分娩结束后,2 组的汉密尔顿焦虑量表和汉密尔顿抑郁量表评分均比分娩前更低,简化版分娩自 我效能量表(CBSEI-C32)评分均比分娩前更高,且观察组均比对照组更优,均有统计学差异(P 均 < 0. 05). 结论 将正念减压疗法结合助产士全程护理应用于初产妇自然分娩中,可改善妊娠结局和初产妇的心理状态,缩短产程,减 少产后出血量,改善其分娩时疼痛控制情况和自我效能. [ABSTRACT FROM AUTHOR]

Copyright of Xinjiang Agricultural Sciences is the property of Xinjiang Agricultural Sciences Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To observe the expression of human β defensin 2（hBD-2）in the human peripheral blood mononuclear cells（PBMCs）stimulated by adenosine triphosphate（ATP）in vitro，and to explore its molecular mechanism through interleukin 1 β（IL-1β）changes in order to improve the body´s anti-infective ability and to provide a basis for the clinical application. Methods Peripheral blood was obtained from healthy volunteers，and PBMCs were isolated and compounded into the cell suspension. PBMCs were then divided into six groups as follows：the blank group which was not treated，and 0，25，50，50，100，and 200 μmol/L ATP groups which were added with HBSS solution and 100 μL each of 25，50，50，100，and 200 μmol/L ATP；hBD-2 and IL-1β in the supernatant were collected at 12 and 24 h of incubation， respectively，and hBD-2 and IL-1β in the supernatant were detected by ELISA. Results Compared with the blank group and 0 μmol/L ATP group，the levels of hBD-2 and IL-1β in the culture supernatant of PBMCs in the ATP groups increased to various degrees（all P<0. 01）. Except for the blank group and 0 μmol ATP group，the levels of hBD-2 and IL-1β in the culture supernatant of PBMCs cultured for 24 h were higher than those cultured for 12 h in the same group（both P<0. 01）. The levels of hBD-2 and IL-1β were positively correlated in the culture supernatants of PBMCs treated with ATP for 12 or 24 h（r=0. 494，0. 725，respectively，both P<0. 01）. Conclusion ATP can induce the up-regulation of hBD-2 expres⁃ sion in the human PBMCs，and the expression change of hBD-2 is consistent with that of IL-1β，suggesting that ATP-in⁃ duced hBD-2 expression is closely related to IL-1β，and they may interact with each other. [ABSTRACT FROM AUTHOR]

Copyright of Piezoelectrics & Acoustooptics is the property of Piezoelectric & Acoustooptic and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Mental Health Journal / Zhongguo Xinli Weisheng Zazhi is the property of Chinese Mental Health Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)