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磁共振（MR）是一种被广泛使用的医学成像方式。针对某些序列的 MR 影像不易直接获得、需要由其他序列的MR影像转换的问题，提出一种基于细节增强的MR序列转换方法。该方法基于条件生成对抗网络构建了残差模板合成模块 ResGAN和细节增强合成模块 EnGAN，设计了一种端到端的网络结构。在一组配准过的神经纤维瘤T1序列影像和STIR序列影像上进行了测试，结果表明，相比于现有方法，提出的方法更好地还原了边界细节和信号强度细节。

Copyright of Journal of Atomic & Molecular Physics (1000-0364) is the property of Journal of Atomic & Molecular Physics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the differences of protein expressions in the primary tumors, adjacent tissues, and metastatic tumors of gastrointestinal neuroendocrine neoplasms. Methods Nine patients with gastrointestinal neuroendocrine tumors (GI-NENs) with liver metastasis who underwent surgery at the National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences from July 2015 to April 2019 were selected. The protein expressions of the primary tissues, liver metastatic tissues, and adjacent tissues were detected by the data independent acquisition (DIA) technology. P<0.05 and | log2FC|>0.5 (FC as the difference multiple) were used as the criteria to identify the differentially expressed proteins in the primary tissues vs adjacent tissues, primary tissues vs liver metastatic tissues, primary tissues with different degrees of differentiation, and liver metastatic tissues with different degrees of differentiation. The differentially expressed proteins were investigated by volcano map analysis, cluster analysis, Gene Ontology (GO) function analysis, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. Results Compared with adjacent tissues, 85 proteins were downregulated and 42 proteins were upregulated in the primary tissues of gastric NENs. The differentially expressed proteins were mainly enriched in the biological processes related to the regulation of guanosidase triphosphate activity and the catabolism of deoxyribonucleoside monophosphate, the glycosaminoglycan biosynthesis chondroitin sulfate/dermatan sulfate, pantothenate, and CoA biosynthesis signaling pathways. 114 proteins were downregulated and 155 proteins were upregulated in the primary tissues of intestinal NENs. The differentially expressed proteins were mainly enriched in the biological processes related to glutathione metabolism and sulfur compound metabolism, collecting duct acid secretion, and taurine and hytaurine metabolism signaling pathways. Compared with the primary tissues of neuroendocrine cancers (NECs), 168 proteins were downregulated and 278 proteins were upregulated in G1-2 differentiation primary tissues. The differentially expressed proteins were significantly enriched in biological processes such as DNA metabolism and DNA replication, as well as replication, mismatch repair, and other pathways. Compared with the metastatic tissues of NECs, 95 proteins were downregulated and 97 proteins were upregulated in G1-2 differentiated metastases. The differentially expressed proteins were significantly enriched in the activity and catalytic activity of transcriptional coactivators, base excision repair, and protein efflux pathways. Compared with G1 differentiated primary tissues, 530 proteins were downregulated and 211 proteins were upregulated in G1 differentiated metastatic tissues. Compared with G2 differentiated primary lesions, 53 proteins were downregulated and 96 proteins were upregulated in G2 differentiated metastatic tissues. Compared with the primary lesions of NECs, 109 proteins were downregulated and 92 proteins were upregulated in the metastatic tissues of NECs. In G1 and G2 differentiated GI-NENs, there are many similar signal pathways enriched in differentially expressed proteins between primary lesions and metastases, while only one signal pathway enriched in differentially expressed proteins between primary and metastatic tissues of NECs is the same as that enriched in differentially expressed proteins between primary and metastatic tissues of GI-NENs, which is the drug metabolism signal pathway. The differentially expressed proteins in G1 differentiated primary and metastatic tissues were mainly expressed in cytoplasm (20.26%), mitochondria (18.67%), and nucleus (15.48%). The differentially expressed proteins in the primary and metastatic tissues of G2 differentiation were mainly expressed in the cytoplasm (20.24%), nucleus (18.25%), and cell membrane (15.08%). The differentially expressed proteins in the primary and metastatic tissues of NECs were mainly expressed in the nucleus (23.78%), cytoplasm (22.7%), and cell membrane (11.35%). Conclusion The protein expressions of GI-NENs in the primary tissues, adjacent tissues, and metastatic tissues were significantly different in different sites and degrees of differentiation. [ABSTRACT FROM AUTHOR]

Copyright of Progress in Modern Biomedicine is the property of Publishing House of Progress in Modern Biomedicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To determine the reasonable stope structural parameters for the sublevel drilling stage open stope and subsequent filling mining method in Hongling Lead Zinc Mine, numerical simulation was employed to study 16 different scenarios with roof thicknesses of 3 m, 5 m, 7 m, and 10 m, and stope lengths of 20 m, 30 m, 40 m, and 60 m, respectively. The stress, displacement, and plastic zone distribution of each scenario with a roof thickness of 3 m were compared. The results indicate that the stability of the stope in Hongling Lead Zine Mine is fairly good when the roof thickness is 3 m and the stope length is 35 m for the sublevel drilling stage open stope and subsequent filling mining method. [ABSTRACT FROM AUTHOR]

Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Experimental Technology & Management is the property of Experimental Technology & Management Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Industrial Water Treatment is the property of CNOOC Tianjin Chemical Research & Design Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

An active passive hybrid control system (MRTMD) was proposed to combine a magnetorheological damper (MRD) and a tuned mass damper (TMD). The vibration of water supply and drainage pipelines was controlled when passing through embankments caused by the operation of pumping station units. Linear quadratic regulator (LQR) based optimal control algorithm was utilized to optimize the parameters of the active passive hybrid vibration control system, in order to minimize the acceleration of the structure. Magnetorheological damper damping was stable enough to change the damping frequency in the new system, compared with the traditional single-tuned mass damper. Firstly, a simulation signal was constructed to simulate the load excitation of pump station units during operation, the vibration response of pump station pipeline was also used to compare with a single TMD and MRD control, in order to verify the applicability and effectiveness of the MRTMD for pump station pipeline vibration reduction. Secondly, shock waves were used as excitation to simulate and analyze the control effect of pipeline dynamic response, in response to the phenomenon of water hammer during opening and closing of the unit or the abnormal vibration under extreme working conditions. The damping force and displacement hysteresis curve were used to explore the robustness and vibration reduction of the output resistance force; Finally, MRTMD was applied to the water supply and drainage pipeline project in the Beijiang Dam in Guangdong Province. The simplified two-degree-of-freedom mass, stiffness, and damping matrices of the pipeline were solved using load inversion and then established the pipeline vibration dynamics equation. Taking the vibration reduction efficiency as the evaluation index, the vibration reduction efficiency of the new system on the water supply and drainage pipeline structure passing through the embankment was analyzed from the time domain perspective. The effective vibration reduction frequency range and energy reduction efficiency of each main frequency of MRTMD were also analyzed from the frequency domain perspective. The results show that the damping force provided by MRTMD shared a wide range, stable output, and strong energy dissipation. Better control was achieved in the acceleration response of pipeline structure, when passing through the embankment, with a damping efficiency of 37.56%-38.07%. There was a slightly better control in the displacement response of the structure, compared with the acceleration response, with a damping efficiency of 40.23%-41.38%, and a damping effect of 33.9% at the pipeline passing through the embankment. The vibration reduction was superior to single TMD and MRD control; There was the weakening effect of MRTMD on the main frequency energy of various vibration sources during operation in a frequency domain. Among them, the mechanical vibration energy caused by the rotation of the main shaft (such as rotation frequency and doubling frequency) was reduced to 27.46% and 75.88%, respectively, while the vibration energy was significantly reduced to 36.46% for medium to low frequency vibration that caused by water flow impact and axial vortices formed in the impeller. [ABSTRACT FROM AUTHOR]

Copyright of Laser Technology is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Science Technology & Engineering is the property of Chinese Society of Technology Economics and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Acoustic wave logging technology is an effective means to find out the underground rock mass structure and crack distribution law. In the logging engineering of deep thermal reservoir, the sensor needs to work continuously in a high temperature environment. High temperature factors are the main cause of sensor failure, and the relationship between the probability of sensor failure and the temperature increase is an exponential trend. Reasonable thermal design is an effective means to improve the high temperature resistance of the sensor. The data acquisition and processing circuit of the ultrasonic imaging sensor was designed according to the actual application environment, and the design method of the sensor internal elements was proposed. According to the heat transfer theory, the heat transfer coupling model of the circuit board was established, and COMSOL software was used to simulate the thermal analysis of the circuit, which provides a reliable basis for the structural design, circuit layout and temperature resistance evaluation of the sensor. Sensor performance tests were conducted in well D35 and well D22 which located in the Xiongan New Area. The experimental results show that the proposed thermal design method can effectively improve the temperature resistance of the sensor, and the heat transfer model can effectively simulate the actual environment, which can be widely used in the temperature resistance design of the sensor under thermal radiation conditions. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Zhengzhou University: Engineering Science is the property of Editorial Office of Journal of Zhengzhou University: Engineering Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to scientifically undertake industrial transfer and promote coordinated economic and environmental development, the relative index of environmental pollution, response intensity measurement model and geographic detector were used to study the environmental pollution in Henan municipalities and its relationship with undertaking industrial transfer from 2007-2018. The results show that the environmental pollution index of most cities in Henan Province from 2007 to 2018 show a decreasing trend and the environmental situation is improved, and the spatial pattern of environmental pollution does not change much, forming a pattern of “high in the northwest and low in the southeast”. There are regional differences in the environmental pollution effects of undertaking industrial transfer, with Xinyang City having a strong response, Anyang City and Xuchang City having a stronger response, the cities of Zhoukou, Luohe, Hebi and Sanmenxia having a weak response, and other cities having a general response. The influence of undertaking industrial transfer on the spatial differentiation of environmental pollution is larger, while the influence of technological innovation level and infrastructure status is smaller. [ABSTRACT FROM AUTHOR]

Copyright of China Sciencepaper is the property of China Sciencepaper and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

There are problems such as cumbersome process, long processing time, and poor detection effect when the traditional image recognition algorithm is used to recognize the numbers in the instrument dial. Aiming at the above problems, a lightweight instrument dial detection method based on deep learning is proposed. Based on a single-shot multi-scale detection method (SSD), the proposal uses deep separable convolution instead of standard convolution to design feature extraction networks to improve feature expression capabilities and lightweight performance. At the same time, an anchor boxes construction process based on the distribution of ground truth boxes is proposed. In the process, an index that can quantify the matching degree of anchor frames (matching rate) is designed, and an anchor box scheme with a higher matching rate and a smaller number is constructed. Experimental results show that the proposed algorithm has less model parameters and computation, higher detection accuracy, and can obtain real-time processing speed in CPU environment. [ABSTRACT FROM AUTHOR]

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Materiae Compositae Sinica is the property of Acta Materiea Compositae Sinica Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Computer-Aided Design & Computer Graphics / Jisuanji Fuzhu Sheji Yu Tuxingxue Xuebao is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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