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目的总结分析妊娠合并库欣综合征患者的临床特点、诊疗经过和母儿预后，优化其妊娠期管理。方法回顾性收集2006年1月至2022年8月在中山大学附属第一医院住院治疗的8例妊娠合并库欣综合征患者的临床资料并随访新生儿结局，总结其临床特征、治疗方法及妊娠结局。结果8例患者中，并发子痫前期4例，孕前糖尿病2例，妊娠期糖尿病5例，低钾血症8例。实验室检查均发现血清皮质醇升高、昼夜节律消失，24 h尿皮质醇升高，血促肾上腺皮质激素下降；影像学检查肾上腺彩超或MR检查提示肾上腺肿瘤。8例孕妇中3例选择于妊娠中期行腹腔镜手术，4例选择保守治疗，产后行腹腔镜手术，术后病理均提示肾上腺皮质腺瘤。8例患者中自然流产1例，足月产1例和早产6例，7例活产中顺产1例，剖宫产6例。7例新生儿中低出生体重儿3例；新生儿多发畸形1例，新生儿左侧重复肾1例，转儿科4例，死亡2例，随访中发现1例幼儿在2岁时确诊为肾病综合征。结论妊娠合并库欣综合征罕见且高危，需要多学科团队进行确诊、管理和长期随访。

Copyright of Uranium Geology is the property of Uranium Geology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hubei Open Vocational College is the property of Journal of Hubei Open Vocational College Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the effect of sodium‑glucose co‑transporter 2 inhibitor (SGLT2i) on spermatogenesis and the quality of sperm in the mice with type 2 diabetes mellitus (T2DM). Methods Twenty‑one 8‑week‑old male db/db mice were randomized into three groups (seven mice in each group) using a random number table method: db/db group (received vehicle), Dapa group [received dapagliflozin (1 mg·kg-1 ·d-1 ) ], and Cana group [received canagliflozin (10 mg·kg-1 ·d-1 ) ], orally daily for five weeks. Five littermate db/m mice were chosen as the normal control group. Body weight and the blood glucose levels were monitored in all mice. Sperm concentration and motility were analyzed using a computer‑assisted semen analysis system. Testicular morphology was evaluated using HE staining, and testicular cell apoptosis was examined using terminal deoxynucleotidyl transferase‑mediated dUTP nick end labeling (TUNEL) and immunohistochemistry staining. GC‑2 spermatogonia cells, were divided into three groups: normal control (vehicle), PA group (100 μmol/L palmitic acid intervention), and PA+Dapa group (100 μmol/L palmitic acid combined with 30 μmol/L dapagliflozin intervention) and treated for 48 h. Oxidative stress levels and apoptosis‑related indices were assessed using Western blotting, flow cytometry and test kits. One‑way analysis of variance or Brown‑Forsythe/Welch was used to compare between groups. Results Compared with db/db mice, dapagliflozin and canagliflozin significantly reduced fasting and postprandial blood glucose levels and the area under the glucose curve (all P<0.05). Both interventions increased sperm viability and progressive motility, as well as curve velocity and mean path velocity (all P<0.05). They also decreased activated caspase‑3 expression, TUNEL‑positive spermatogenic tubule ratio, and cell ratio (all P<0.05). In GC‑2 cells, intervention with dapagliflozin reduced intracellular reactive oxygen species levels, malondialdehyde content, increased superoxide dismutase activity, decreased apoptosis rate, and increased B‑cell lymphoma 2 (BCL2) expression (all P<0.05) compared with the PA group. Conclusion SGLT2i provide additional protective effects on testicular structure and sperm quality in db/db mice with T2DM in addition to their hypoglycemic effects. SGLT2i may protect against diabetes‑induced spermatogenesis impairment by attenuating testicular oxidative stress and apoptosis. [ABSTRACT FROM AUTHOR]

Copyright of Packaging & Food Machinery is the property of Packaging & Food Machinery Magazine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Coal Geology & Exploration is the property of Xian Research Institute of China Coal Research Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To observe the effect of Chinese herbal tea in the treatment of throat pain and swelling after anterior cervical spine surgery. Methods Totally 80 patients undergoing anterior cervical spine surgery were randomly divided into the control group and the observation group, with 40 cases in each group. Both the groups received routine treatment and nursing after surgery, and the observation group was given additional treatment of Chinese herbal tea. The degree of throat pain and swelling was evaluated at 24 h, 3 days and 7 days after surgery. Results The Numerical Rating Scale on throat pain in the observation group was lower than that in the control group at 24 h, 3 days and 7 days after surgery respectively(P＜0. 01). The degree of throat swelling in the observation group was lower than that in the control group at 24 h, 3 days and 7 days after surgery respectively(P＜0. 01). Conclusion The Chinese herbal tea is effect in relief of throat pain and swelling after anterior cervical spine surgery. (目的 观察中药代茶饮治疗颈椎前路术后咽喉部肿痛的临床效果。方法 80例颈椎前路术后的患者随机分为对照组和观察组, 每组40例。对照组手术后给予常规治疗和护理, 观察组在对照组基础上增加中药代茶饮治疗。评估两组术后24 h、术后3 d、术后7 d咽喉部疼痛评分、肿胀程度。结果 观察组患者术后24 h、术后3 d、术后7 d咽喉部疼痛数字评分(NRS)低于对照组, 差异有统计学意义 (P＜0. 01)。观察组患者术后24 h、术后3 d、术后7 d咽喉部肿胀程度低于对照组, 差异有统计学意义 (P＜0. 01)。结论 颈椎前路术后给予中药代茶饮, 能够进一步缓解术后咽喉部疼痛和肿胀程度。)

Inflammatory bowel disease( IBD) is a disease characterized by chronic, recurrent intestinal inflammation, including Crohn's disease( CD) and ulcerative colitis( UC). Etiology and pathogenesis of IBD are unknown, and the treatment is difficult. In recent years, immunocellular therapy represented by regulatory T (Treg) cell therapy and dendritic cell (DC) therapy has developed rapidly in the field of immune-related disease treatment, and some progress has also been made in the treatment of IBD. This review will introduce application and progression of Treg cell therapy and DC therapy in IBD treatment. [ABSTRACT FROM AUTHOR]

Objective: To study the changes of immunoglobulins( IgG, IgA, IgM) and helper T cell Th9 subset, and their correlation with insulin-like growth factor-1 (IGF-1) and S-100B protein in patients with Parkinson's disease (PD). Methods: A total of 108 patients with PD confirmed in Hebei Hospital of Traditional Chinese Medicine were enrolled as study group between December 2020 and December 2022. According to disease severity, they were divided into mild group (35 cases), moderate group (44 cases) and severe group (29 cases); a total of 108 healthy adults were enrolled as control group. Levels of immunoglobulins and Th9 subset were compared between study group and control group, and levels of immunoglobulins, Th9 subset, IGF-1 and S-100B protein were compared among mild group, moderate group and severe group. Correlation between immunoglobulins, Th9 subset and IGF-1, S-100B proteins were analyzed by Pearson correlation analysis. Correlation between disease severity and all differential indexes in PD patients were analyzed by Spearman correlation analysis. Results: IgM level in study group was lower than that in control group, and which was the lowest in severe group, followed by moderate group and mild group (P<0.05). Levels of IgG, IgA, IL-9 and Th9 subset in study group were higher than those in control group, and which were the highest in severe group, followed by moderate group and mild group (P<0.05). IGF-1 level was the lowest in severe group, followed by moderate group and mild group, while level of S-100B protein was on the contrary (P<0.05). Results of Pearson correlation analysis showed that IgM level was positively correlated with IGF-1 level, while negatively correlated with level of S-100B protein. Levels of IgG, IgA, IL-9 and Th9 subset were negatively correlated with IGF-1 level, while positively correlated with level of S-100B protein (P<0.05). Results of Spearman correlation analysis showed that the disease severity was negatively correlated with IgM and IGF-1 levels, while positively correlated with levels of S-100B protein, IgG, IgA, IL-9 and Th9 subset (P<0.05). Conclusion: IgM level is decreased, while levels of IgG, IgA and Th9 subset are increased in PD patients. Changes of the above indexes are significantly correlated with IGF-1 and S-100B, which can be applied to evaluate disease severity. [ABSTRACT FROM AUTHOR]

Copyright of Plateau Meteorology is the property of Plateau Meteorology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Snowmelt runoff and soil freezing have been combined to seriously exert on the rill networks and soil erosion intensity in the black soil region of northeastern China. The dynamic development of rill networks can be used to quantitatively extract the parameters of erosion. Previous studies have focused primarily on the runoff erosion caused by rainfall. Only a few studies were to consider the combined effects of snowmelt runoff and freezing. Currently, available methods cannot fully meet the high precision of rill morphology. Therefore, it is very necessary to systematically investigate the rill erosion under combined effects using high-precision extraction. This study aims to simulate the snowmelt runoff scouring on the frozen (-20°C freezing) and non-frozen slopes (10°C), refilled with black soil from northeastern China. A 0°C ice-water mixture was used to simulate the snowmelt runoff scouring. Meanwhile, three-dimensional laser scanning was employed to obtain the point cloud data of the slope surface after different times of scouring, until the eroded surface stabilized. The Digital Surface Model (DSM) of Difference (DoD) with point cloud reverse engineering was used to detect and parameterize the micro-topographic pattern (e.g., development of rill networks and erosion area, erosion volume, rill length, and rill density). The results show that there was a significant impact of freezing-induced temperature on the development of rill networks: (1) The frozen slope was more prone to develop the rill networks. The erosion rate after each scouring was significantly higher than that on the nonfrozen slopes. Upon reaching stability, the erosion area, erosion volume, and rill length were 291%, 557%, and 437% of those on the non-frozen slopes, respectively; (2) The cumulative erosion volume of the frozen and non-frozen slopes showed similar patterns during the rill development. But there were noticeable differences along the cross-sectional direction of the rills. On the frozen slopes, the width-depth ratio (RW/D) of the rill cross-sections decreased rapidly at the rill intersections with accelerated downcutting, whereas, the width and depth of rills increased linearly and stably. On the non-frozen slopes, the RW/D at the midslope cross-sections increased with the number of scouring events, thus accelerating lateral erosion, while the RW/D at other sections decreased with the number of scouring events with accelerated downcutting; (3) The relative error range was -12.70% to 4.42% for the Differential Digital Surface Model (DoD) with ArcGIS hydrological processing and GeoMagic point cloud reverse engineering models for the frozen slopes, with an absolute mean relative error of 5.48%, and an extraction accuracy of over 94%. The combined extraction with GeoMagic and ArcGIS showed a great contribution to obtain the rill parameters on the freeze-treated slopes. The finding can serve as a promising potential to the rill development under complex eroding settings. [ABSTRACT FROM AUTHOR]

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Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Drainage & Irrigation Machinery Engineering / Paiguan Jixie Gongcheng Xuebao is the property of Editorial Department of Drainage & Irrigation Machinery Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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全球能源互联网是实现新能源资源在全球范围内合理配置和高效利用的重要发展方向。基于模块化多电平换流器（modular multilevel converter，MMC）的柔性直流输电技术凭借其可以为无源电网提供支撑和控制灵活的特点，正逐渐成为构建全球能源互联网的重要技术手段之一。对柔性直流输电技术在全球能源互联网背景下的应用进行了深入研究。首先梳理了柔性直流输电在全球能源互联网中的3种典型应用场景。接着利用PSCAD/EMTDC仿真研究了传统柔性直流在典型应用场景下的故障特性，分析了其应用于全球能源互联网时的不足。针对这些不足，提出了一种具有解耦运行能力的基于锂电池储能装置的有源型柔性直流输电技术，对其拓扑结构和控制策略进行了介绍。最后在PSCAD中仿真验证了所提出的有源型MMC在全球能源互联网应用场景下隔离交流系统故障对直流侧系统的功率冲击的能力。

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