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为了解决当前紫外线吸收剂与活性成分复配应用于体系时，存在刺激性、溶解性、光稳定性方面的问题，通过鸡胚绒毛尿囊膜实验、防晒增效性实验、自由基清除实验研究4种高亚油酸型油脂米糠油、红花籽油、小麦胚芽油和芝麻油的安全性、紫外吸收性、防晒增效性、抗氧化性。结果表明：米糠油、红花籽油、小麦胚芽油和芝麻油安全性高，可应用于光防护类特殊用途化妆品；4种油脂与长波紫外线吸收剂二乙基氨基羟基苯甲酰苯甲酸己酯（APLUS）、中波紫外线吸收剂甲氧基肉桂酸乙基己酯（OMC）及广谱紫外线吸收剂奥克立林相溶性佳，25 ℃放置28 d后未出现溶解性问题；芝麻油与APLUS复配时，长波紫外线吸收增幅比例最高，为17.81%；与OMC复配时，米糠油作为溶剂对于中波紫外线吸收增幅比例最高，可达28.83%；奥克立林复配红花籽油时，全波段紫外线吸收增幅比例最大，达到45.77%；4种高亚油酸型油脂都能有效减缓OMC光降解的速率，其中芝麻油与OMC的复配体系在光照9 h后辐照损失率最小，为2.88%；4种高亚油酸型油脂都具有一定的DPPH自由基及羟自由基清除能力，其中米糠油DPPH自由基清除率最高，EC50值为0.036 49 g/mL，小麦胚芽油羟自由基清除率最高，EC50值为0.053 36 g/mL。米糠油、红花籽油、小麦胚芽油和芝麻油不仅可作为化妆品中一种基质原料，同时由于其安全性、防晒增效性和抗氧化性，可应用于产品中以进一步提高产品的光防护性能。 In order to solve the current problems of irritation, solubility and light stability when the ultraviolet（UV） absorber and active ingredients were compounded in the system, the safety, UV absorption, sunscreen synergism and antioxidation properties of four high linoleic acid oils (rice bran oil, safflower seed oil, wheat germ oil and sesame oil) were investigated through chicken embryo chorioallantoic membrane test, sunscreen potentiation and free radical scavenging test. The results showed that rice bran oil, safflower seed oil, wheat germ oil and sesame oil were highly safe and could be used in photoprotection special purpose cosmetics. The four oils had good solubility with long wave UV absorber diethylaminohydroxybenzoyl hexylbenzoate (APLUS), medium wave UV absorber methoxyethyl hexyl cinnamate (OMC) and broad-spectrum UV absorber aucylin, and there was no stability problem after being stored at 25 ℃ for 28 d. When sesame oil was mixed with APLUS, the increase rate of long wave UV absorption was the highest, which could increased by 17.81%. When compounded with OMC, rice bran oil as solvent had the highest increase rate of medium wave UV absorption, which was 28.83%. When aucylin was compounded with safflower seed oil, the increase rate of absorption of full band UV radiation reached the maximum, which was 45.77%.The four high linoleic acid oils could effectively slow down the rate of OMC photodegradation, and the compound system of sesame oil and OMC had the lowest irradiation loss rate of 2.88% after 9 h of light irradiation.The four high linoleic acid oils had certain DPPH and hydroxyl radical scavenging ability, among which rice bran oil had the highest DPPH radical scavenging rate with EC50 value of 0.036 49 g/mL, and wheat germ oil had the highest hydroxyl radical scavenging rate with EC50 value of 0.053 36 g/mL. Therefore, rice bran oil, safflower seed oil, wheat germ oil and sesame oil not only can be used as a base material in cosmetics, but also can be used in products to further improve their photoprotection properties due to their safety, sunscreen potentiation and antioxidant properties.

随着我国“蓝色粮仓”战略的提出，水产品的营养及相关研究日益得到人们关注。除了作为优质蛋白质来源，许多水产品还富含油脂，特别是其油脂中含有对人体生理与健康有重要作用的二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）等长链多不饱和脂肪酸。水产油脂具有较高的营养价值，如磷虾油和微藻油开发前景广阔。但水产油脂极易氧化，其提取和生产加工工艺对其品质均有重要影响。重点围绕水产油脂的提取、精炼和DHA、EPA富集工艺进行综述，分析了不同方法的优缺点以及工业化生产的可行性。介绍了水产油脂的营养、安全，以及提高其氧化稳定性的方法。水产油脂资源的开发利用已成为必然趋势，水产油脂类产品将会更加多元化。 With the proposal of the "blue granary" strategy in China, the nutrition and related research of aquatic products have attracted more and more attention. In addition to being a source of high-quality protein, many aquatic products are also rich in oil, especially long-chain polyunsaturated fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which play an important role in human physiology and health. Aquatic oil has high nutritional value, for example krill oil and microalgae oil have broad prospects for development. However, aquatic oil is easy to be oxidized, and its extraction and processing technology have an important impact on its quality. The extraction and refining of aquatic oil and the enrichment of DHA and EPA were reviewed, the advantages and disadvantages of different methods and the feasibility of applying them to industrial production were also analyzed. The nutrition and safety of aquatic oil, as well as the methods to improve the oxidative stability of aquatic oil were introduced. The development and utilization of aquatic oil resources has become an inevitable trend, and aquatic oil products will be more diversified.

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This article delves into a thorough analysis of the current state of food veterinary drug residue testing and proposes a framework for establishing a scientific and rigorous standard system for veterinary drug residue testing. The main challenges currently faced include inadequate research on pretreatment techniques, limitations in the sensitivity of trace residue detection methods, the accuracy of simultaneous multi-residue detection, and the stability of rapid testing product quality. Additionally, there are issues with the limited variety and quantity of standard substances, as well as insufficient monitoring of their quality and performance. To address these issues, this article proposes a framework for constructing a veterinary drug residue testing standard system that encompasses key elements such as basic general standards, sample management, detection process control, quality tracing, and service management. The objective is to provide a reference framework for the development of a scientific and effective standard system for veterinary drug residue detection. [ABSTRACT FROM AUTHOR]

Objective To investigate the application value of the facial artery perforator pedicled V-Y advancement flap in the treatment of middle and lower facial tumors in the elderly population. Methods A retrospective analysis was performed on the data of 35 elderly patients who underwent extensive resection of middle and lower facial tumors and reconstruction using the facial artery perforator pedicled V-Y advancement flap from January 2017 to December 2023 in Department of Plastic Surgery, Affiliated Hospital of Guangdong Medical University. Collect their basic information, postoperative flap survival rate, incidence of postoperative complications, and patient satisfaction, and conduct retrospective analysis. Results All 35 patients' skin flaps survived, and there were 2 cases of skin flap tip bruising after surgery, with a total complication rate of 5.71%. After a follow-up period of 3 to 6 months postoperatively, there was no significant difference in the color and texture of the recipient skin flap compared to the surrounding skin. The overall patient satisfaction rate was 94.29%. Conclusion The V-Y advancement flap of the perforating branch of the facial artery has reliable blood supply, similar color and texture to the recipient area, low cost in the donor area, and high patient satisfaction. It has high clinical application value in the treatment of lower facial tumors in elderly patients. [ABSTRACT FROM AUTHOR]

Objective To establish a training system for laboratory operators in Biosafety Level 2 laboratories, aimed at enhancing the knowledge level of personnel, standardizing operational skills, and reducing laboratory accidents. Methods The Delphi method was employed to conduct two rounds of consultations with 17 experts in the field of biosafety from Beijing, Shanghai, Xinjiang, Fujian, Anhui, Chongqing, Guangzhou, and Shenzhen to determine the indicator system, while the Analytic Hierarchy Process (AHP) was used to establish the weights of the indicators. Results The response rates for the two rounds of questionnaires were 94.44% and 100.00%, respectively, with expert authority coefficients of 0.962 and 0.944. The Kendall's coefficient of concordance (W) was high (all P < 0.01). Ultimately, the training system was defined to include 5 primary indicators, 21 secondaiy indicators, and 83 tertiary indicators. Conclusion This training system is structurally complete and content-rich, demonstrating strong scientific validity and reliability, and can serve as a reference for the training and assessment of laboratory operators in Biosafety Level 2 laboratories. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Dermatovenereology is the property of Xi'an Jiaotong University Periodicals Center and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of China Surfactant Detergent & Cosmetics (2097-2806) is the property of China Surfactant Detergent & Cosmetics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi is the property of Journal of Clinical Hepatology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Central China Normal University is the property of Huazhong Normal University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

High quality farmers are cultivated to provide usable rural talents for the implementation of the rural revitalization strategy, one of the ultimate goals of building a strong agricultural country is to significantly increase farmers’ income and achieve agricultural modernization. Whether cultivating high-quality farmers can help increase farmers’ income has not been rigorously confirmed. Therefore, based on the survey data of cultivating high-quality farmers in Hubei Province in 2023 and the data of cultivating professional farmers from 2016 to 2022, regression analysis was conducted using Ologit model and mediation effect model. The results indicated that: ①Regardless of the identity attribute of individual attribute of farmers, participating in high-quality farmer training and increasing the training time limit are beneficial for driving an increase in farmers’ income. ②The cultivation of high-quality farmers promotes the increase of farmers’ income mainly through three intermediate channel variables: skill improvement, theoretical enrichment, and network expansion, all of which have a complete mediating effect. ③The cultivation of high-quality farmers through large-scale production also requires the promotion of “moderate scale operation”. Based on this, suggestions were put forward to strengthen funding expenditures, expand the scale of cultivation, deepen the reform of cultivation courses, enhance professionalism, and establish a sound mechanism for assessing post training income. [ABSTRACT FROM AUTHOR]

Objective To investigate and analyze the distribution of serum cytokeratin 19 fragment antigen 21-1 (CYFRA21-1) and squamous cell carcinoma-associated antigen (SCCA) levels in healthy pregnant women during pregnancy and to assess their diagnostic value for cervical cancer in pregnancy. Methods A total of 441 healthy pregnant women and 69 patients with cervical cancer in pregnancy who attended the Obstetrics and Gynecology Hospital of Fudan University from Jan 2021 to May 2024 were selected, and 165 healthy women in the Physical Examination Center of the Obstetrics and Gynecology Hospital of Fudan University were included in the same period as the control group. The healthy pregnant women were divided into 143 in early pregnancy (T1 group), 147 in middle pregnancy (T2) and 151 in late pregnancy (T3). Serum CYFRA21-1 and SCCA values were detected and analyzed in all groups. Oneway ANOVA, independent samples t-test, Mann-Whitney U-test, Kruskal-Wallis H-test, logistic analysis, and ROC curves were used for comparative analysis. Results The CYFRA21-1 and SCCA values were 1.66 (1.19-2.17) ng/mL and 0.8 (0.6-1.0) ng/mL in the control group, 3.07 (2.11-4.14) ng/mL and 0.9 (0.7-1.3) ng/mL in the healthy pregnant women group, and were 4.33 (2.99-7.60) ng/mL and 1.8 (0.9-8.5) ng/mL in the patients with cervical cancer in pregnancy group, respectively. There was a statistically significant difference in the two serum values between every two groups (P<0.05). CYFRA21- 1 levels were 3.13 (2.46-4.05) ng/mL, 1.89 (1.50-2.53) ng/mL and 4.19 (3.48-5.43) ng/mL in the T1, T2, and T3 groups, respectively; and SCCA levels were 0.9 (0.7-1.1) ng/mL, 0.7 (0.6-1.0) ng/mL and 1.2 (0.8-1.7) ng/mL, respectively. The results of T1 and T3 groups were higher than those of the control group (P<0.05); however, there was no statistically significant difference between the results of the T2 group and those of the control group (P>0.05). The areas under the ROC curves for the diagnosis of cervical cancer in pregnancy for CYFRA21-1, SCCA, human epididymis protein 4 (HE4), anticarcinoembryonic antigen (CEA) and joint indicators were 0.684, 0.724, 0.612, 0.791 and 0.913, with sensitivities of 36%，48%，38%，57% and 73%，specificities of 96%，97%，89%，86% and 99%, respectively. The cut-off values of each indicator were 6.05 ng/mL, 2.60 ng/mL, 51.45 pg/mL and 1.75 ng/mL, respectively. Conclusion Serum CYFRA21-1 and SCCA levels were higher in pregnant women during early and late pregnancy compared with non-pregnant individuals, while they were not statistically different from non-pregnant women during mid-trimester. CYFRA21-1 and SCCA have diagnostic value for patients with cervical cancer during pregnancy. [ABSTRACT FROM AUTHOR]

Copyright of China Pulp & Paper is the property of China Pulp & Paper Magazines Publisher and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Modern Preventive Medicine is the property of Modern Preventive Medicine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Shenyang Pharmaceutical University is the property of Shenyang Pharmaceutical University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

OBJECTIVE: To probe into the effects of national centralized drug volume-based procurement policy, drug negotiation and key monitoring on application of proton pump inhibitors (PPI) in hospitals, so as to provide data support for the rational application of PPI and evaluation of implementation effect on related policies. METHODS: Application data of PPI from 2018 to 2022 were extracted from the drug use database of sample hospitals of the National Pharmaceutical Information Network (including 892 hospitals, with 645 tertiary hospitals and 247 secondary hospitals). Consumption amount and proportion, consumption sum and proportion, daily defined dose system (DDDs) and daily defined dose (DDC) and other indicators were analyzed and compared. RESULTS: From 2018 to 2022, due to the influence of relevant policies, the consumption sum and DDC of PPI in sample hospitals decreased year by year. The reduction of PPI injection was greater than that of PPI oral preparation. The consumption amount structure and consumption sum structure of PPI changed significantly. The consumption amount of PPI injection and DDDs of most injection varieties decreased significantly. CONCLUSIONS: From 2018 to 2022, Consumption sum and consumption amount of PPI injection in sample hospitals decrease significantly, yet the alternative application among different clinical varieties still deserves further evaluation. [ABSTRACT FROM AUTHOR]

Objective To investigate the effectiveness of drug-coated balloons (9DCB) in treating acute coronary lesions and their impact on inflammatory response. Methods A total of 192 patients with acute myocardial infarction who underwent percutaneous coronary intervention (9PCI) within 12 hours of admission were selected. According to the PCI treatment strategy, they were divided into the DCB group (9102 patients) and the drug-eluting stent (9DES) group (990 patients). The study observed the effects of the two treatment plans on acute coronary lesions and inflammatory response. Results There were no statistically significant differences between the two groups in general baseline data, lesion vessels, DCB/DES sizes used, or pre-and post-procedure TIMI flow grades (9P＞0.05). The immediate lumen diameter and lumen gain in the DCB group were inferior to those in the DES group (9P＜0.01), and the incidence of vascular dissection in the DCB group was higher than in the DES group (9P＜0.01). At the 9-month follow-up, the late lumen loss (9LLL) in the DCB group was better than that in the DES group (9P＜0.01), and the fractional flow reserve (9FFR) was similar between the two groups. There were no statistically significant differences in the incidence of major adverse cardiac events (9MACE) and bleeding events caused by dual antiplatelet therapy between the two groups (9P＞0.05). Inflammatory markers in both groups were significantly lower than pre-procedure levels, and at follow-up, the inflammatory markers in the DCB group were significantly lower than those in the DES group (9P＜0.01). Conclusion The efficacy of DCB in treating acute coronary lesions is not inferior to that of DES. Additionally, DCB has a better inhibitory effect on the inflammatory response of local lesions, suggesting potentially better long-term outcomes. [ABSTRACT FROM AUTHOR]

In order to solve the problems of loss of moving targets due to the flight status of the unmanned aerial vehicle (UAV) itself, the interference of the environment the randomness of the target and other reasons in the process of collecting moving target image information by the UAV platform, a deep deterministic policy gradient (DDPG) algorithm UAV following method based on moving target recognition was proposed. Facing the vehicle target on the highway, the relationship among the height, posture and high-speed vehicle motion of the UAV was analyzed. the velocity adaptive model of the target detection frame rate of the mobile platform was estab lished, and the flight attitude and speed of the UAV were corrected in real time according to the motion state of the target, so that the UAV could maintain the relative position and angle with the target. Then, based on the value network of DDPG algorithm, the value of UAV taking spe- cific actions in different states was estimated; the strategy network generates the strategy of UAV taking actions in a given state, and gives UAV flight altitude and speed control parameters for target tracking, so that the UAV could automatically adjust the flight state according to the movement change of the target, and realize the adaptive tracking of the moving target. Simulation experiments show that the DDPG algorithm can provide stable flight attitude data and a reliable control basis for the UAV following task, and the UAV can track the ground moving target in a circular area with a speed range of 0~33 m/s and a radius of 120 m in real time, and can achieve continuous and stable tracking within the endurance range. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Shanghai University / Shanghai Daxue Xuebao is the property of Journal of Shanghai University (Natural Sciences) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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以菜籽分离蛋白为原料，在琥珀酸酐酰化改性的基础上采用3种多糖（羧甲基壳聚糖、氧化葡聚糖、羧甲基纤维素）协同TG酶催化对菜籽蛋白进行了糖基化修饰，再通过热诱导制备改性菜籽蛋白凝胶，研究不同多糖与酰化协同修饰对菜籽蛋白凝胶结构和功能性质的影响。结果表明：糖基化-酰化修饰菜籽蛋白，形成了致密且均匀的凝胶网络结构，使其溶胀性能、流变性能和凝胶强度均得到了改善。其中，羧甲基壳聚糖协同琥珀酸酐酰化修饰菜籽蛋白，获得的菜籽蛋白凝胶硬度最大，为92.337 g，弹性较好，为0.960，溶胀率为8.432 g/g；其表面疏水性最高，为1 305.1，自由巯基含量最低，为1.73 μmol/g；其内部形成的网络结构整齐，呈规则且密集的圆形。糖基化-酰化修饰后，菜籽蛋白功能性质的改变可能与其二级结构中α-螺旋、β-折叠、β-转角和无规则卷曲含量均有不同程度的变化有关。 Based on the acylation modification with succinic anhydride, rapeseed protein isolate was modified with three kinds of polysaccharides(carboxymethyl chitosan, oxidized dextran, carboxymethyl cellulose) and TG enzyme. Modified rapeseed protein gel was prepared by heat induction to study the effects of different polysaccharides and acylation modification on the structure and functional properties of rapeseed protein gel. The results showed that glycosylation-acylation modified rapeseed protein to form a compact and uniform gel network structure, which improved its swelling properties, rheological properties and gel strength. When the rapeseed protein was modified with carboxymethyl chitosan and succinic anhydride, the hardness of rapeseed protein gel was the best (92.337 g), elasticity was better (0.960), the swelling rate was 8.432 g/g, the surface hydrophobic was the highest(1 305.1), the free sulfhydryl group content was the lowest (1.73 μmol/g), and the internal network formed uniform structure with regular and dense circle. After the modification of glycosylation-acylation, the change of functional properties of rapesecd protein was possibly related to the changes of the contents of α -helix, β -folding, β -turning and random coil.

Objective: To retrospectively analyze the effect of Bailing capsule on microinflammation and renal function in patients with diabetic nephropathy. Methods: From January 2021 to September 2022, the clinical data of 120 patients with diabetic nephropathy admitted to our hospital were retrospectively collected and divided into the hypoglycemic and lipid-lowering group (56 cases) and the Bailing capsule group (64 cases) according to the treatment methods. The hypoglycemic and lipid-lowering group was treated with metformin tablets and rosuvastatin calcium tablets. The bailing capsule group was treated with bailing capsules on the basis of the hypo- glycemic and lipid-lowering group. The curative effect after 3 months of treatment, glucose and lipid metabolism index, micro-inflammatory state and renal function before and after 3 months of treatment were compared between the two groups. Results: The therapeutic effect of the Bailing capsule group after 3 months was higher than that of the hypoglycemic and lipid-lowering group (P<0.05). After 3 months of treatment, level of serum fasting blood glucose (FBG), glycated hemoglobin (HbA1c), total cholesterol (TC), triglyceride (TG), interleukin-6 (IL-6), hypersensitive C-reactive protein (hs-CRP), serum levels of creatinine (SCr), urea nitrogen (BUN) and 24 h urinary albumin (24 h) in both groups UTP) and urinary albumin excretion rate (UAER) were lower than before treatment, and the Bailing capsule group was lower than the hypoglycemic and lipid-lowering group (P<0.05). The level of serum interleukin-10 (IL-10) in the two groups was higher than that before treatment, and that in the Bailing capsule group was higher than that in the hypoglycemic and lipid-lowering group (P<0.05). Conclusion: Bailing capsule coyld effectively improve glucose and lipid metabolism, renal function and microinflammation in patients with diabetic nephropathy, with good curative effect. [ABSTRACT FROM AUTHOR]

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