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由于遥感图像具有分辨率高和背景信息复杂的特点，其对目标检测的精确性和鲁棒性要求越来越高，因此遥感图像处理领域逐渐引入了卷积神经网络算法。然而此类算法通常模型复杂且计算量庞大，难以在空间与资源受限的星上平台高效运行。针对这一问题，提出一种基于宇航级现场可编程门阵列（Filed Programmable Gate Array, FPGA）的卷积神经网络硬件加速架构，并选用YOLOv5s作为目标网络，采用输入与输出通道并行展开以及数据流水线控制的策略进行架构设计。实验结果表明，在使用该处理架构加速YOLOv5s的推理阶段，卷积模块的工作频率可以达到200 MHz，其运算性能高达394.4GOPS（Giga Operations Per Second），FPGA的功耗为14.662 W，数字信号处理（Digital Signal Processing, DSP）计算矩阵的平均计算效率高达96.29%。

研究了一类特殊情形(m=1)的重心权Hermite有理插值，证明了该插值函数的二阶导数在插值节点和非插值节点处分别以O(h2d-1)和O(h2d-3)的速度收敛于函数f″(x)。数值例子进一步验证了方法的有效性。

Copyright of Food Science & Technology & Economy is the property of Grain Science & Technology & Economy Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

n-3多不饱和脂肪酸（n-3 PUFA）具有多种生理活性，其主要有3种存在形式，其中甘油酯型n-3 PUFA因其生物利用度高和不易被氧化而优于游离型和乙酯型。然而，目前鲜有对甘油酯型n-3 PUFA进行高纯度富集的方法。为了对甘油酯型n-3 PUFA的高值化更加深入的研究提供参考，综述了富集甘油酯型n-3 PUFA的3种常见方法（物理一步法、两步法和酶一步法）及优缺点。物理一步法可以避免产物氧化，但得率较低；两步法工艺复杂，并有可能产生环境污染；而酶一步法具有简单、高效等优点，成为学者们关注的焦点。现有脂肪酶对甘油酯型n-3 PUFA的富集能力有限，还需进一步发掘富集能力更强的选择性脂肪酶 There are three main forms of n-3 polyunsaturated fatty acids (n-3 PUFA) with a variety of physiological activities, of which glyceride-type n-3 PUFA is superior to free and ethyl ester forms due to its high bioavailability and less susceptibility to oxidation. However, there is few method for the enrichment of glyceride-type n-3 PUFA with high purity. In order to provide a reference for a more in-depth study of the high value of glyceride-type n-3 PUFA, three common methods (physical one-step, two-step and enzymatic one-step), and their advantages and disadvantages of enriching glyceride-type n-3 PUFA were reviewed. The physical one-step method can avoid product oxidation, but the yield is low; the two-step method is complicated and may produce environmental pollution; while the enzymatic one-step method has the advantages of simplicity and high efficiency, which has become the focus of scholars attention. The existing lipases are limited in their ability to enrich glyceride-type n-3 PUFA, and there is a need to further explore selective lipases with higher enrichment capacity.

Copyright of Journal of Vibration, Measurement & Diagnosis is the property of Nanjing Hangkong Daxue and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To systematically review the progress in the application of artificial intelligence in the field of pediatric otolaryngology-head and neck surgery at home and abroad, aiming to provide reference for the development and clinical practice in the future. Methods Literature related to the application of artificial intelligence in otolaryngology, head and neck surgery were searched from PubMed, Web of Science and Embase databases in June 2024, regardless of the research type, publication date and language restrictions. Subsequently, using the National Heart, Lung, and Blood Institute Study Quality Assessment Tools (NHI-SQAT) and the Oxford 2011 Levels of Evidence (LOE), tables were designed to assess the quality of the articles and select authentic and effective literature. Literature content was extracted, and a systematic review of current status and future prospects of artificial intelligence in this field was conducted. Results After preliminary screening of abstracts and titles, full-text reading, supplementary retrieval, and exclusion of literature that did not meet quality standards, a total of 38 articles were finally included. Artificial intelligence has been widely used in the diagnosis and treatment of pediatric otolaryngological diseases in various forms. Significant clinical effects have been achieved through methods such as machine learning and big data processing, enabling surgical assistance and the establishment of diagnostic and treatment models. In recent research, the diagnosis and treatment of pediatric otitis media, assessment of pediatric hearing loss, preoperative planning and postoperative guidance, and telemedicine are becoming the main directions of exploration and application of artificial intelligence. Conclusions Application of artificial intelligence in pediatric otolaryngology head and neck surgery at home and abroad has been gradually extended in recent years. As the use of artificial intelligence in assisted diagnosis and treatment has been gradually accepted by the medical community, the application platform for artificial intelligence will become diversified in the future. [ABSTRACT FROM AUTHOR]

Objective: To discuss the effect of downregulating microRNA-208a (miR-208a) on the resistance of the colorectal cancer cells to 5-fluorouracil (5-FU), and to clarify its related molecular mechanism. Methods: Real-time fluorescence quantitative PCR (RT-qPCR) method was used to detect the expression levels of miR-208a and secreted frizzled-related protein 1(SFRP1) mRNA in the 5-FUresistant colorectal cancer cell line HT-29/5-FU and its parent HT-29 cells. The HT-29/5-FU cells were transfected with miR-208a inhibitor plasmid and its negative control plasmid (inhibitor-NC), and SFRP1 small interfering RNA (si-SFRP1) and its negative control plasmid (si-NC), either separately or in combination, followed by treatment with 5-FU. The cells were divided into inhibitor-NC group, miR-208a inhibitor group, miR-208a inhibitor+si-NC group, and miR-208a inhibitor+si-SFRP1 group. MTT assay was used to detect the proliferation activities of the cells and the resistance indexes were calculated; Annexin Ⅴ-FITC/PI double staining and flow cytometry were used to detect the apoptotic rates of the cells after treated with different concentrations of 5-FU; Western blotting method was used to detect the expression levels of SFRP1, β -catenin, P-glycoprotein (P-gp), and ATP-binding cassette subfamily B member 1(ABCB1) proteins in the cells in various groups; dual-luciferase reporter gene assay was used to validate the targeting relationship between miR-208a and SFRP1. Results: Compared with HT-29 cells, the expression level of miR-208a in the HT-29/5-FU cells was increased (P<0. 05), and the expression level of SFRP1 mRNA was decreased (P<0. 05). Compared with inhibitor-NC group, the proliferation activity of the cells in miR-208a inhibitor group was decreased (P<0. 05), the resistance index was decreased, the apoptotic rate was increased (P<0. 05), and the expression levels of β-catenin, P-gp, and ABCB1 proteins in the cells were decreased (P<0. 05). The dual-luciferase reporter gene assay results showed that SFRP1 was a target gene of miR-208a and miR-208a could negatively regulate the expression of SFRP1. Compared with miR-208a inhibitor+si-NC group, the proliferation activity of the cells in miR-208a inhibitor+si-SFRP1 group was increased (P<0. 05), the resistance index was increased, the apoptotic rate was decreased(P<0. 05), and the expression levels of β -catenin, P-gp, and ABCB1 proteins in the cells were increased (P<0. 05). Conclusion: Downregulation of miR-208a can improve the resistance of the HT-29/5-FU cells to 5-FU by targeting and upregulating the SFRP1 expression, thereby inhibiting the transmission of the Wnt signaling pathway. [ABSTRACT FROM AUTHOR]

Copyright of Industrial Water Treatment is the property of CNOOC Tianjin Chemical Research & Design Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Diamond & Abrasives Engineering is the property of Zhengzhou Research Institute for Abrasives & Grinding and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Journal of Anhui Agricultural Sciences is the property of Journal of Anhui Agricultural Sciences Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

As a classical physical chemistry experiment, traditional Fe(OH)3 colloid electrophoresis has suffered from the following shortcomings, such as the waste of Fe(OH)3 colloid, the long dialysis operation time, and the lack of inquiry learning. To overcome such shortcomings, we have made the following improvements on the original experiment: 1) realizing the recycling of Fe(OH)3 colloid by regenerating Fe(OH)3 colloid waste via colloid redissolution route; 2) improving the purification efficiency of coarse Fe(OH)3 colloid through optimizing the dialysis procedure; 3) introducing AgI colloid exploratory investigation to enhance the innovation and interestingness of this experiment; 4) introducing paper electrophoresis to cultivate the ability to connect fundamental experiments with practical applications. The above improvements have been fully confirmed and already applied in the colloid electrophoresis experiment performed in our university. As expected, such improvements have aroused enthusiastic responses from the students attended this course, thus providing a valuable reference for us to improve other classical experiments. [ABSTRACT FROM AUTHOR]

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Copyright of Water Conservancy & Electric Power Technology & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的 机械取栓时代，探索如何因地制宜建立急性卒中救治体系，让更多急性卒中患者能在时间窗 内及时到达有条件的医院，从而提高区域性急性卒中急诊救治的整体水平。 方法 从2014年开始，在院内及医院所在的区域，由单位行政部门及区域卫生行政部门牵头协调， 制定卒中救治的相关政策、规定，陆军军医大学第一附属医院神经内科作为技术主导，开展卒中诊治 的培训及帮助各级部门、医院建立相应的卒中救治流程、规范。观察我院卒中救治的关键绩效指标 及协作单位救治水平的改善情况。 结果 ①院内急诊通道的建立：由院长亲自参与，院医疗科作为卫生行政部门进行督导、协调，院内 参与卒中救治的急救部、神经内科、神经外科、神经影像科、检验科、心电图室及护理保障中心积 极参与，使急性缺血性卒中的入院-静脉溶栓（door-to-needle time，DNT）时间由绿色通道建立前的 71 mi n缩短至53 mi n，入院-动脉穿刺（door-to-puncture time，DPT）时间由104 min缩短至82 min，入院-血 运重建（door-to-revascularization time，DRT）时间由144 min缩短至117 min。②区域性卒中救治网络的建 立：极大提高我院急性缺血性卒中的救治能力，2014年本科静脉溶栓及血管内治疗总病例数为7例， 2016年提高到112例，区域内初级卒中中心的卒中防治关键绩效指标明显改善。 结论 院内卒中救治绿色通道及区域性卒中救治网络的建立，能提高卒中救治水平及救治率，改善 区域性卒中救治水平。应进一步改进卒中救治通道及网络并进行更大范围的推广。 Abstract: Objective In the context of current era of mechanical thrombectomy, this study is to explore how to establish acute stroke emergency system suited for local condition, make more stroke patients arrive at the qualified hospitals within the therapy time window, and increase the overall level of regional stroke rescue treatment. Methods Since 2014, the hospital and regional health administrative departments began to assist the local hospitals to make the policy and regulation of stroke rescue. The Department of Neurology of the Third Military University Affiliated First Hospital took the lead in aspect of technique, developed the training of diagnosis and treatment of stroke, provided assistance in establishing rescue workflow and assisted the collaborative hospitals to establish stroke emergency workflow and criterion. The improvement of key performance indicator (KPI) of acute ischemic stroke (AIS) care of our hospital, and change of stroke rescue level of collaborative hospitals were observed. Results (1) Establishment of stroke fast channel: the hospital director participated in the work. The department of medical affairs carried out the monitoring and coordination work. Many departme actively participated in the work, including Emergency, Neurology, Neurosurgery, Neuroimaging, Laboratory Medicine, ECG, and Nursing Security. The door-to-needle time (DNT) was shortened from 71 minutes before to 53 minutes now; the door-to-puncture time (DPT) was shortened from 104 minutes before to 82 minutes now; the door-to-revascularization time (DRT) was shortened from 144 minutes before to 117 minutes now. (2) Establishment of regional stroke rescue network: the level of AIS emergency care of our hospital got greatly improved. The total number of patients treated with IV thrombolysis and endovascular treatment increased from 7 in 2014 to 112 in 2016; the KPIs of stroke care in primary stroke center in this region also got improved significantly. Conclusion The establishment of in-hospital stroke fast channel and regional stroke rescue network can increase the level of stroke emergency care and regional stroke cure rate. It’s worthwhile to be further improved and widely promoted.

Copyright of Shipin Kexue/ Food Science is the property of Food Science Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of University Chemistry is the property of Peking University, College of Chemistry & Molecular Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agriculturae Zhejiangensis is the property of Acta Agriculturae Zhejiangensis Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Wildlife / Yesheng Dongwu Xuebao is the property of Chinese Journal of Wildlife Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Chinese Expert Consensus 2023 on Endovascular Treatment for Acute Large Vessel Occlusion with Mild Stroke is a summary and analysis of the new progress and new evidence obtained from the recent studies on endovascular treatment for acute large vessel occlusion with mild stroke by the experts organized by the Chinese Interventional Neuroradiology Society of Chinese Stroke Association. This expert consensus covers the definition of mild stroke, and intravenous thrombolysis and endovascular treatment for acute large vessel occlusion that begins with mild stroke. The aim is to provide guidance for professionals and social workers engaged in stroke prevention and treatment, especially the endovascular treatment, care and rehabilitation of acute ischemic stroke, as well as relevant governmental agencies, healthcare administrators, pharmaceutical companies, healthcare demand parties, and other stakeholders. [ABSTRACT FROM AUTHOR]

Karst ecological civilization is required to construct for energy production and consumption in the Karst rocky desertification (KRD) area in southern China. It is of great practical significance for rural areas to determine the distribution of animal and poultry manure resources, in order to realize the highly efficient energy utilization. In this study, the research area was selected as Guizhou Province with the serious KRD in southern China. The nine cities/prefectures were collected from the statistical yearbook as the data source. Four types of livestock manure resources were selected to estimate the potential of per capita livestock utilization. The regional characteristics of livestock and poultry resources were defined to quantitatively using mathematical statistics. There was some difference in livestock and poultry manure resources between Karst counties and nonkarst counties, as well as a correlation with the level of KRD. A biogas mode was proposed for the energy utilization of livestock and poultry manure resources. The economic feasibility of the model was measured as well. The following three conclusions were drawn: 1) The theoretical resources of four types of livestock and poultry manure were 52.874 million tons in 2017, and the recoverable resources were 36.358 6 million tons, which was dominated by cow manure and pig manure. Spatially, the growth trend was from the southeast to northwest, with significant differences among counties. 2) The amount of manure fertilizer resources was 18.15 million tons, the amount of energy conversion resources was 18.208 6 million tons, the amount of standard coal was reduced, and the annual energy consumption of firewood was replaced by 15.254 4 million tons, indicating the comparative advantages of energy utilization in livestock manure. Cites of Zunyi and Bijie in the northwest shared the promising potential for large-scale utilization. 3) rural energy was dominated by electrification and gasification in recent years, considering the rural energy development trend, regional resource endowment, population age structure, and population shrinkage. Some recommendations were given to construct the rural energy production and consumption revolution demonstration zone, due to the population shrinkage and population age structure. The large-scale biogas project/bio-gas model was proposed to select livestock manure as the raw material in the plateau mountainous area with potential-mild KRD. The optimal structure of energy consumption with ecologically friendly, social, and economic feasibility can be expected to alleviate the regional energy poverty and economic pressure, and then reduce the incidence of diseases for a better indoor environment. The finding can provide a strong reference to consolidate the rock desertification control for the health and wellbeing of local community households. [ABSTRACT FROM AUTHOR]

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Copyright of Gold (1001-1277) is the property of Gold Magazine Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This study is to investigate the effect and mechanism of Stellera chamaejasme L. (SCL) on inhibiting proliferation of hepatocellular carcinoma cells, providing basis for the pathological mechanism study and clinical treatment of primary hepatocellular carcinoma. Firstly, CCK-8 assay was performed to illustrate the ability of tumor growth in the HepG2215 cells treated with SCL serum containing blood. Western blot was used to detect the expression of YAP1 (yes-associated protein 1) protein in the HepG2215 cells. Secondly, Yap1flox/flox and Yap1LKO mice were induced to form liver tumors in situ by DEN (diethylnirtosamine) /TCPOBOP (3,5-dichloro-2- [4- (3,5-dichloropyridin-2-yl) oxyphenoxy] pyridine). SCL decoction was given to the stomach of the mice for 7 d, the liver was taken out, and the general shape of the liver tumor was observed. H&E was performed to observe the pathological morphology in tumor tissue. Western blot was to detect the expressions of YAP1 in the liver tumor tissues. The results from cell experiment demonstrated that SCL inhibited the proliferation of HepG2215 cells and decreased YAP1 expression. Moreover, animal experiment revealed that SCL reduced tumor volume and YAP1 expression both in Yap1flox/flox and Yap1LKO mice with tumors in liver. The hepatocellular carcinoma tumor volume of Yap1LKO mice in NS group reduced when compared with Yap1flox/ flox mice. Yap1 knockdown reduced the effect of SCL inhibiting tumor growing in SCL group when compared with Yap1flox/flox mice. LC-MS was used to detect the active components of SCL drug-containing serum and water decoction, and molecular docking was carried out with YAP1 protein. LC-MS results showed that the active ingredients were caffeic acid 3-sulfate, 5-benzyloxolan-2-one, 3,4,5-trihydroxy-6- [ (2-oxo-2h-chromen-5- yl) oxy] oxane-2-carboxylic acid and isoscopoletin in SCL. Among them, caffeic acid 3-sulfate, 3,4,5-trihydroxy-6- [ (2-oxo-2h-chromen-5-yl) oxy] oxane-2-carboxylic acid and isoscopoletin directly formed stable docking with YAP1 protein. These results suggest that SCL inhibits liver tumor cell proliferation by reducingYAP1 expression. [ABSTRACT FROM AUTHOR]

Preventive environmental public interest litigation contains the inherent mechanism of risk prevention, which can help improve the regulatory system against environmental risks and respond to the public’s demand for preventing environmental risks. Currently, although China has adopted the expression of ‘significant risk’ at the legislative level, legislators have not provided relatively comprehensive and specific explanations on its inherent nature, specific judicial identification methods, and proof standards for specific causal relationships. How to correctly identify and confirm ‘significant risks that harm public interests’ is left to the discretion of the courts: either by uniformly recognizing administrative actions as references, directly adopting risk assessment results from scientific and technological evaluations, or independently evaluating significant risks. It is also unclear whether the term applies to environmental pollution or ecological destruction. Fundamentally, due to a lack of a unified understanding of ‘significant risks,’ judges mostly make judgments based on environmental risk assessment reports, which cannot properly handle the relationship between preventive environmental judicial powers and environmental administrative powers, resulting in judicial discretion becoming formalistic. Fundamentally, the judicial determination of significant risks faces limitations such as inconsistent connotations, misplaced recognition subjects and unclear standards, and rigid confidence mechanisms, making it difficult for lawsuits to correctly handle the dialectical relationship between judicial initiative and restraint. To solve the confusion caused by unclear concepts and mechanical judgments and to properly give play to the judiciary’s initiative, this article responds to practical problems in three ways: first, defining the connotations of ‘significant risks,’ clarifying their concepts, and confirming their basic objects by taking a literal decomposition and responsibility backtracking approach; second, defining the identification criteria for significant risks, using dynamic adjustments under risk assessment uncertainty as the premise for defining identification criteria and using the high probability of serious harm consequences as the causal requirement for identification criteria; and third, optimizing the confidence mechanism of significant risks, using the organic combination of objective scientific rationality and subjective social rationality as the inherent logic of the confidence mechanism and adopting a phased confidence mechanism arrangement for two different levels of significant risk identification. [ABSTRACT FROM AUTHOR]

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