At present, it is the main method to establish a phosphogypsum centralized reservoir to dispose phosphorus industrial waste by landfill, but the establishment of a phosphogypsum centralized reservoir has extremely high requirements on the hydrogeological conditions of the reservoir area. In order to avoid the leakage of phosphogypsum polluting the local groundwater environment and provide a reference for the actual construction and design of the reservoir as well, taking the phosphogypsum centralized storage project in Liulichong Village, Zhicheng Town, Yidu City, Hubei Province as an example, a field hydrogeological survey, geophysical exploration, karst groundwater tracer test and other methods were comprehensively used in this study to find out the hydrogeological characteristics of the sample area. In addition, Qtacer2 software was used to obtain hydrogeological parameters, which contributed to analyze flow direction of karst groundwater and the structural characteristics of the karst water-bearing medium in the study area. It is found that there is a reverse fault (F2) in the northern part of the reservoir area, which is the main controlling factor of karst development direction in the reservoir area; It is confirmed by geophysical exploration that there are underground flow channels in the karst area. The tracer test data show that the groundwater flow velocity in the reservoir area is slow and there exists a groundwater main runoff zone, controlled by F2 fracture, whose direction is NE70°; By analyzing the characteristics of the tracer concentration duration curve, it is found that the degree of karst development in the reservoir area is uneven, which is characterized by the coexistence of fissures, single small pipelines, and local karst caves, having the characteristics of heterogeneity and anisotropy; Based on the analysis of Qtacer2 data, the hydraulic parameters (including dispersion coefficient, longitudinal dispersion, friction coefficient, Reynolds number, Sherwood number, Schmidt number) were estimated. The research results provide a basis for the site selection and construction of the reservoir area and the protection of water resources. [ABSTRACT FROM AUTHOR]