Search

Copyright of Chinese Journal of Applied Mechanics is the property of Chinese Journal of Applied Mechanics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Study on Optical Communications / Guangtongxin Yanjiu is the property of Study on Optical Communications Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The improvement of transportation infrastructure can reshape the economic geogra‐ phy patterns. The opening of high-speed railways promotes the flow of innovation elements among regions, enhances the knowledge spillover effect, affects regional innovation activities, or even affects the structure of regional knowledge innovation network. Based on the extant literature, this article summarized the relationship between high-speed railways and knowledge innovation in cities along railway lines in terms of the exact impact, differential performance and the mechanism, and further explained the micro mechanism of the impact of the opening of high-speed railways on regional knowledge innovation from the perspective of enterprises. According to the literature analysis, this article draws the following conclusions. Firstly, high-speed rail‐ ways do have an impact on knowledge innovation, but there are regional differences, which are related to geographical distance and urban heterogeneity. Secondly, the opening of high-speed railways promotes the flow and agglomeration of innovation factors, and expands knowledge spillover effects, which will affect regional knowledge innovation. However, both the agglomeration effect and knowledge spillover effect have two sides, so they show different influence effects in different regions. Thirdly, the opening of high-speed railways is conducive to expanding the commuting field, broadening knowledge channels and increasing temporary agglomeration, so as to increase the opportunities for enterprises to obtain innovative talents, cross-regional co‐ operation and knowledge sharing, and promote their innovative output. Finally, this article puts forward an analytical framework and some topics worthy of in-depth discussion. [ABSTRACT FROM AUTHOR]

Copyright of Mechanical & Electronic Control Engineering is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Carsologica Sinica is the property of Institute of Karst Geology, CAGS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Engineering Science Research & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Science & Technology of Food Industry is the property of Science & Technology of Food Industry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

[Purpose/Significance] At present, governments at different levels in China are faced with some problems and challenges in opening up government data such as lagging policy legislation, data unable to meet public demand, insufficient platform service function and integration, imperfect data openness innovation mechanism, and a lack of unified management institutions. The purpose of this paper aims at construction of a stage maturity model to build an evaluation indicator system to measure government data openness maturity, It is important for the local government to understand which level of development their open data is at and which areas need to be improved, in order to comprehensively understand and grasp the actual level of local government data openness in China, which is important for strengthening the construction of sunshine government and e-government, optimizing the process of government data openness, and promoting the innovative development of government data openness. [Method/Process] Based on the idea of the software capability maturity model Capability Maturity Model (CMM), the Chinese government data openness maturity model was constructed, and then a data openness evaluation indicator system was also established on the basis of the maturity model. The government data openness maturity model includes strategic level, data level, technical level, organizational level and application level, and the levels are divided into five categories: initial level, document level, development level, open level and optimization level. The evaluation indicator system consists of 5 primary indicators, 11 secondary indicators and 35 tertiary indicators. The combination weights of the indicators were calculated by using the AHP-entropy weight method. Then, we designed the scoring rules, set the scoring criteria, and scored the four municipalities directly under the central government of China according to the actual situation. [Results/Conclusions] According to the ratings of the four municipalities, Shanghai has a good overall performance, followed by Beijing, Tianjin, and Chongqing. The municipalities directly under the central government are better in terms of related policies launched, but they are lacking in terms of platform function construction, the degree of perfection of local policies and regulations, and the interaction ability with users, which need to be further strengthened. The open government data evaluation indicator system proposed in this paper needs continuous improvement in terms of indicator selection and scoring criteria. In some aspects, the effect of using one indicator alone may not be satisfactory, and the follow-up study involving more elements will summarize more experiences and collect more experts' opinions in the field of government data openness to further improve the government data openness maturity evaluation indicator system. [ABSTRACT FROM AUTHOR]

To investigate the effect of SP600125 on the proliferation, cell cycle, apoptosis and invasion of human cervical cancer HeLa cells. Methods CCK-8 method was used to detect the proliferation of HeLa cells treated with different concentrations of SP600125 at different time points. The 20 μmol/L of SP600125 was determined for subsequent experiments. Cell proliferation ability was detected using plate clone formation assay; nuclear morphology was observed by DAPI staining; cell cycle and apoptosis were measured by flow cytometry; cell migration and invasion were detected by cell scratch and Transwell methods; the mRNA and protein levels of p53, Mad2L1 and CDC20 were measured by qRT-PCR and Western blot after SP600125 treatment at different time points. Results Compared with control group (0.1%DMSO), cells proliferative activity were reduced by 10, 20, 30, 40 and 50 μmol/L SP600125 treatment for 24h. Compared with control group, the rate of apoptosis was significantly increased in SP600125 treatment groups, and the cell proportion in G2/M phase increased (P<0.001), while the cell proportion in G0/G1 phases cells was reduced after SP600125 treatment for 24h and 48h (P<0.001), and the clonal number, migration and invasion ability of HeLa cells also decreased significantly (P<0.001). qRT-PCR and Western blot results showed a significant decrease in Mad2L1 mRNA and protein expression (P<0.05) and a significant increase in p53 and CDC20 mRNA and protein expression (P<0.01). Conclusion SP600125 can induce cell cycle arrest of cervical cancer HeLa cells in G2/M phase by upregulating p53 and CDC20 and downregulating Mad2L1 expression, and promote cell apoptosis to inhibit cell proliferation, migration and invasion. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Henan University of Technology Natural Science Edition is the property of Henan University of Technology Journal Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of CT Theory & Applications is the property of Editorial Department of CT Theory & Applications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of South China Agricultural University is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Guangxi Normal University - Natural Science Edition is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Lung Cancer is the property of Chinese Journal of Lung Cancer and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Diabetes Mellitus is the property of Chinese Journal of Diabetes Mellitus and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)