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Objective: To study the influence of electromyographic biofeedback therapy（EMGBFT) combined with mirror therapy（MT) on lower limb motor and balance function in stroke patients. Method: Sixty patients with hemiplegia after stroke were randomly divided into two groups: MT based EMGBFT group and EMGBFT group, 30 patients in each group. On the basis of conventional rehabilitation, the patients in the EMGBFT group received sham MT stimulation combined with EMGBFT, and the patients in the MT based EMGBFT group received MT combined with EMGBFT. Before and after treatment, the lower limb motor function of the patients was evaluated using Fugl-Meyer assessment scale-lower extremity (FMALE) and surface electromyography - integrated electromyography (iEMG) of knee flexion and ankle dorsiflexion, co-contraction ratio (CR) . Plantar pressure - symmetry index (SI) of mean pressure and contact area of both feet, elliptical area of body center of gravity, anteroposterior (AP) and mediolateral (ML) displacement distance of body center of gravity under eye- opening and eye- closed states were calculated to evaluate patients’weight-bearing and balance function. Result: After treatment, FMA-LE, CR and iEMG of biceps femoris and rectus femoris under knee flexion, tibialis anterior and medial gastrocnemius under ankle dorsiflexion were markedly ameliorated in the two groups (P<0.01) . After treatment, in the eye-opening state, the SI of mean pressure and contact area of both feet, elliptical area of body center of gravity, AP and ML displacement distances of body center of gravity were greatly enhanced in the two groups (P<0.05, P<0.01), in the eye-closed state, the SI of mean pressure and contact area of both feet, ML displacement distances of body center of gravity were observably ameliorated in the two groups (P<0.05, P<0.01) . Compared with the EMGBFT group, the FMA-LE, iEMG of biceps femoris and tibialis anterior muscles, elliptical area of body center of gravity, AP and ML displacement distance of body center of gravity with eyes open, SI of contact area of both feet with eyes closed had more significant changes in the MT based EMGBFT group after treatment（P<0.05, P<0.01) . Conclusion: Electromyographic biofeedback therapy combined with mirror therapy can improve lower limb motor and balance function in stroke patients, the underlying mechanism of which may be the activation of lower limb weak muscle motor units, the relief of lower limb spasm, and the improvement of standing static balance ability. [ABSTRACT FROM AUTHOR]

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