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Copyright of Journal of Beijing University of Traditional Chinese Medicine is the property of Journal of Beijing University of Traditional Chinese Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal on Communication / Tongxin Xuebao is the property of Journal on Communications Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the expression and clinical significance of G2 and S phase-expressed-1 (GTSE1) in the gastric cancer (GC) tissues and its adjacent normal gastric tissues. Methods The expression of GTSE1 mRNA and protein in 12 cases of fresh GC tissues and adjacent normal gastric tissues were respectively detected by qRT-PCR and Western blotting. The expression of GTSE1 protein in 56 cases of GC tissues and adjacent normal gastric tissues was evaluated by immunohistochemistry. The relationship between the expression levels of GTSE1 protein and clinical pathological characteristics in patients with gastric cancer was analyzed. At last, the prognostic factors for GC patients was assessed by COX regression model. Results Compared with the adjacent nonnal gastric tissues, GTSE1 protein and mRNA were highly expressed in the gastric cancer tissues (both P < 0. 05). The high expression of GTSE1 protein was related to the tumor size, degree of differentiation, depth of tumor invasion, lymph node metastasis, and TNM staging (all P <0.05). COX regression model analysis manifested that TNM staging and GTSE1 expression were important independent prognostic factors for patients with gastric cancer (both P<0.05). Conclusion GTSE1 was highly expressed in the GC tissues, and the overex press ion of GTSE1 protein is closely related to the malignant pathological features and poor prognosis. [ABSTRACT FROM AUTHOR]

Copyright of China Sciencepaper is the property of China Sciencepaper and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Northeastern University (Natural Science) is the property of Dongbei Daxue Xuebao and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)