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为了对比不同油体富集物理化性质及功能性质的差异，采用水萃离心法从大豆、花生、葵花籽3种大宗油料种子中提取油体富集物，对比研究了油体富集物的得率、基本成分、粒径、Zeta电位、蛋白质组成、黏度、起泡性、乳化性、分层稳定性以及冻融稳定性。结果表明：大豆油体富集物的得率和固形物含量都显著低于葵花籽和花生油体富集物的（p＜0.05），且具有不易掩盖的豆腥味；3种油体富集物的基本成分之间都存在显著性差异（p＜0.05），蛋白质的分子质量分布也不尽相同；3种油体富集物的粒径和Zeta电位绝对值由小到大顺序均为大豆油体富集物

为了探究葵花籽油体富集物在冰淇淋中应用的可行性，以葵花籽油体富集物作为脂肪来源制备低脂冰淇淋，在无均质条件下研究葵花籽油体富集物添加量对低脂冰淇淋浆料和产品品质的影响。结果表明：冰淇淋浆料的黏度、储能模量和损耗模量都随葵花籽油体富集物添加量的增加而增大，当葵花籽油体富集物添加量为3.5%～4.0%时黏度与对照组相当；浆料中不易流动水和结合水的比例随着葵花籽油体富集物添加量的增加逐渐增大,在4.0%时达到最大；冰淇淋的膨胀率和抗融率随着葵花籽油体富集物添加量的增加先增大后减小；添加葵花籽油体富集物的冰淇淋色泽较差；冰淇淋的硬度和咀嚼性变化规律一致，都是随着葵花籽油体富集物添加量的增大呈现先减小后增大的趋势，弹性变化则相反;冰淇淋黏附性随着葵花籽油体富集物添加量的增加而升高；葵花籽油体富集物添加量为2.5%时冰淇淋感官评分最高。合适的葵花籽油体富集物添加量可以起到与棕榈油相似的效果，因此葵花籽油体富集物可以应用在冰淇淋中。In order to investigate the feasibility of using sunflower seed oil body enrichment in ice cream,low fat ice cream was prepared with sunflower seed oil body enrichment as the fat under the condition of non-homogenization. The effect of the dosage of the oil body enrichment on the quality of low fat ice cream slurry and product was explored. The results showed that the viscosity, storage modulus and loss modulus of ice cream slurry increased with the increase of the oil body enrichment dosage. When the dosage of oil body enrichment was 3.5%- 4.0%, the viscosity was equivalent to that of the control group. The proportion of non-flowing water and bound water in the slurry increased gradually with the increase of the dosage of oil body enrichment, reaching the maximum at 4.0%. The expansion rate and anti-melting rate of ice cream products first increased and then decreased as the increase of the oil body enrichment dosage. The color of ice cream with sunflower seed oil body enrichment was poor. The hardness and chewability of ice cream showed the same change law, which first decreased and then increased with the increase of the oil body enrichment dosage,while the elasticity changed in the opposite direction. The adhesion of ice cream increased with the increase of the oil body enrichment dosage. The sensory score of ice cream was the highest when the dosage of oil body enrichment was 2.5%. The appropriate dosage of sunflower seed oil body enrichment can produce a similar effect as palm oil, and sunflower seed oil body enrichment can be applied in ice cream.

【目的】探讨细胞松弛素B和解冻程序对玻璃微细管法（GMP）玻璃化冷冻小鼠卵母细胞的影响。【方法】以小鼠MII期卵母细胞为模型，研究冷冻前细胞松弛素B预处理、不同解冻程序对小鼠卵母细胞冷冻效果的影响；随后对经GMP玻璃化冷冻的卵母细胞直接进行培养以检测冷冻是否诱发孤雌发育。【结果】与对照组相比．细胞松弛素B预处理的卵母细胞存活率、受精率、卵裂率及囊胚率没有显著差异（89．3％vs91．3％．44．0％vs40．4％，30．0％vs27．7％，4．0％vs6．4％；P〉0．05）；采用连续浓度梯度递减解冻法的受精率明显高于间断浓度梯度递减解冻法（57．4％vs40．4％；P〈0．05），且前者的卵裂率和囊胚发育率也相对较高f40，2％vs27，7％，14．5％vs6．4％；P〉0．05）。冷冻复苏后卵母细胞的孤雌发育率稍高于未经冷冻的卵母细胞（17．1％vs3．2％；P〉0．05）。【结论】细胞松弛素B预处理对MII期小鼠卵母细胞的GMP玻璃化冷冻保存效果没有影响：采用连续浓度梯度递减解冻法能明显提高复苏后卵母细胞的体外发育能力。

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Liver failure is a common clinical syndrome with rapid progression and poor prognosis. Currently, there are still limited internal medical treatment methods for liver failure, and artificial liver support therapy is an effective treatment method. Nonbioartificial liver technology is widely used in clinical practice, and clinicians should determine the starting time, mode, and specific parameters of treatment according to the pathophysiological mechanism and dynamic evolution process of the disease, as well as the specific conditions of patients. Compared with non-bioartificial liver, biological artificial liver can better simulate the biological function of liver cells. At present, substantial progress has been made in its core technology, and related clinical studies are being conducted actively, suggesting a vast potential for future development. This article summarizes and discusses the optimization of non-bioartificial liver technology and the advances in biological artificial liver, in order to provide a reference for the clinical application and research of artificial liver technology. [ABSTRACT FROM AUTHOR]

This paper aims to review treatment delay in first-episode schizophrenia, depression, and bipolar disorder, and to compare related factors of treatment delay in the three first-episode mental disorders. It is found that increased patient responsibility, stigma, lack of disease-related knowledge, lack of access to resources, and insufficient medical support lead to delay treatment, and making patients to have longer course, heavier symptoms, and lower social functions. [ABSTRACT FROM AUTHOR]

Objective: To compare demographic characteristics, clinical characteristics, therapeutic characteristics and physiological indicators of patients with bipolar I disorder and bipolar II disorder. Methods: A total of 381 patients with bipolar disorder(BD) diagnosed by the Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5) were selected, including 302 patients with BD-I (79.27%), 74 patients with BD-II (19.42%) and 5 patients with other specific and related disorders (1.31%). Demographic and clinical characteristics were collected with self-designed clinical information questionnaire. Multivariate logistic regression and multivariate linear regression analysis were used for analysis. Results: Compared with patients with BD-II, patients with BD-I had more risk to have psychotic features (OR = 5. 75, 95% CI: 2. 82-11. 76), longer disease duration, and more repeated transcranial magnetic therapy (OR = 3. 09, 95% CI: 1. 02-9.35), higher uric acid, total cholesterol and high-density lipoprotein. BD-I in Han nationality was more common (OR = 11. 50, 95% CI: 1. 76-75.30), and had lower education level (OR = 10. 22, 95% CI: 1. 1689.77), and less family history of psychosis (OR = 2. 34, 95% CI: 1. 01 5. 42). Conclusion: There are significant differences between BD-I and BD-II in demographic and clinical characteristics, treatment status, and physiological indicators, which could provide clues for exploring the pathogenesis of bipolar disorder. [ABSTRACT FROM AUTHOR]

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